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6J1U
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BU of 6j1u by Molmil
influenza virus nucleoprotein with a specific inhibitor
分子名称: Nucleoprotein, ~{N}-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide
著者Pang, B, Zhang, W.Z, Zhang, H.M, Hao, Q.
登録日2018-12-29
公開日2020-01-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle.
J.Virol., 95, 2021
3P08
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BU of 3p08 by Molmil
Crystal structure of the human BTK kinase domain
分子名称: Tyrosine-protein kinase BTK
著者Yu, C.L, Hymowitz, S.G.
登録日2010-09-27
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A novel, specific BTK inhibitor antagonizes BCR and FcgR signaling and suppresses inflammatory arthritis
To be Published
5GJU
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BU of 5gju by Molmil
DEAD-box RNA helicase
分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD
著者Xu, L, Li, F, Wang, L, Shi, Y.
登録日2016-07-02
公開日2017-05-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
6IYA
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BU of 6iya by Molmil
Structure of the DNA binding domain of antitoxin CopASO
分子名称: Transcriptional regulator CopG family
著者Zhao, R, Li, F, Liu, L, Zhang, X.
登録日2018-12-14
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and allosteric coupling of type II antitoxin CopASO.
Biochem.Biophys.Res.Commun., 514, 2019
5GI4
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BU of 5gi4 by Molmil
DEAD-box RNA helicase
分子名称: ATP-dependent RNA helicase DeaD
著者Xu, L, Wang, L, Li, F, Wu, L, Shi, Y.
登録日2016-06-22
公開日2017-05-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.244 Å)
主引用文献Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
Structure, 25, 2017
3PL9
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BU of 3pl9 by Molmil
Crystal structure of spinach minor light-harvesting complex CP29 at 2.80 angstrom resolution
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
著者Pan, X.W, Li, M, Wan, T, Wang, L.F, Jia, C.J, Hou, Z.Q, Zhao, X.L, Zhang, J.P, Chang, W.R.
登録日2010-11-14
公開日2011-02-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into energy regulation of light-harvesting complex CP29 from spinach.
Nat.Struct.Mol.Biol., 18, 2011
5WWW
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BU of 5www by Molmil
Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA
分子名称: RNA (5'-R(*GP*UP*UP*UP*AP*G)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C
著者Yang, L, Wang, C, Li, F, Gong, Q.
登録日2017-01-05
公開日2017-08-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWZ
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BU of 5wwz by Molmil
Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C
分子名称: RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION
著者Yang, L, Wang, C, Li, F, Gong, Q.
登録日2017-01-05
公開日2017-08-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWX
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BU of 5wwx by Molmil
Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA
分子名称: NICKEL (II) ION, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C
著者Yang, L, Wang, C, Li, F, Gong, Q.
登録日2017-01-05
公開日2017-08-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5XGP
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BU of 5xgp by Molmil
structure of Sizzled from Xenopus laevis at 2.08 angstroms resolution
分子名称: CHLORIDE ION, SULFATE ION, Secreted Xwnt8 inhibitor sizzled
著者Liu, H, Li, Z, Xu, F.
登録日2017-04-15
公開日2017-08-23
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.077 Å)
主引用文献The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins
J. Biol. Chem., 292, 2017
5Y9F
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BU of 5y9f by Molmil
Crystal structure of HPV59 pentamer in complex with the Fab fragment of antibody 28F10
分子名称: Major capsid protein L1, heavy chain of Fab fragment of antibody 28F10, light chains of Fab fragment of antibody 28F10
著者Li, S.W, Li, Z.H.
登録日2017-08-24
公開日2017-10-25
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5Y9C
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BU of 5y9c by Molmil
Crystal structure of HPV58 pentamer in complex with the Fab fragment of antibody A12A3
分子名称: Major capsid protein L1, heavy chain of Fab fragment of antibody A12A3, light chain of Fab fragment of antibody A12A3
著者Li, S.W, Li, Z.H.
登録日2017-08-24
公開日2017-10-25
実験手法X-RAY DIFFRACTION (3.443 Å)
主引用文献Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
5Y9E
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BU of 5y9e by Molmil
Crystal structure of HPV58 pentamer
分子名称: GLYCEROL, MAGNESIUM ION, Major capsid protein L1
著者Li, S.W, Li, Z.H.
登録日2017-08-24
公開日2017-10-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.042 Å)
主引用文献Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus.
MBio, 8, 2017
6LAD
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BU of 6lad by Molmil
Crystal structure of Amuc_1100 from Akkermansia muciniphila
分子名称: Amuc_1100
著者Wang, J, Xiang, R, Zhang, M, Wang, M.
登録日2019-11-12
公開日2020-08-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The variable oligomeric state of Amuc_1100 from Akkermansia muciniphila.
J.Struct.Biol., 212, 2020
6LAF
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BU of 6laf by Molmil
Crystal structure of the core domain of Amuc_1100 from Akkermansia muciniphila
分子名称: Amuc_1100, SULFATE ION
著者Wang, J, Xiang, R, Zhang, M, Wang, M.
登録日2019-11-12
公開日2020-08-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献The variable oligomeric state of Amuc_1100 from Akkermansia muciniphila.
J.Struct.Biol., 212, 2020
1MJT
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BU of 1mjt by Molmil
CRYSTAL STRUCTURE OF SANOS, A BACTERIAL NITRIC OXIDE SYNTHASE OXYGENASE PROTEIN, IN COMPLEX WITH NAD+ AND SEITU
分子名称: ETHYLISOTHIOUREA, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NITRIC-OXIDE SYNTHASE HOMOLOG, ...
著者Bird, L.E, Ren, J, Stammers, D.K.
登録日2002-08-28
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of SANOS, a Bacterial Nitric Oxide Synthase Oxygenase Protein from Staphylococcus aureus
Structure, 10, 2002
3L95
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BU of 3l95 by Molmil
Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus notch homolog protein 1, ...
著者Hymowitz, S.G, de Leon, G.P.
登録日2010-01-04
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Therapeutic antibody targeting of individual Notch receptors.
Nature, 464, 2010
3VEY
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BU of 3vey by Molmil
glucokinase in complex with glucose and ATPgS
分子名称: 6-methoxy-N-(1-methyl-1H-pyrazol-3-yl)quinazolin-4-amine, Glucokinase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Liu, S.
登録日2012-01-09
公開日2012-02-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Insights into Mechanism of Glucokinase Activation: OBSERVATION OF MULTIPLE DISTINCT PROTEIN CONFORMATIONS.
J.Biol.Chem., 287, 2012
5Y4U
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BU of 5y4u by Molmil
Crystal structure of Grx domain of Grx3 from Saccharomyces cerevisiae
分子名称: Monothiol glutaredoxin-3
著者Chi, C.B, Tang, Y.J, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z.
登録日2017-08-05
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
J.Mol.Biol., 430, 2018
5Y4T
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BU of 5y4t by Molmil
Crystal structure of Trx domain of Grx3 from Saccharomyces cerevisiae
分子名称: GLYCEROL, Glutaredoxin
著者Chi, C.B, Tang, Y.J, Zhang, J.H, Dai, Y.N, Abdalla, M, Chen, Y.X, Zhou, C.Z.
登録日2017-08-05
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Biochemical Insights into the Multiple Functions of Yeast Grx3.
J.Mol.Biol., 430, 2018
8BYP
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BU of 8byp by Molmil
Botulinum neurotoxin serotype X in complex with NTNH/X
分子名称: Botulinum neurotoxin type X, NTNH/X
著者Martinez-Carranza, M, Skerlova, J, Stenmark, P.
登録日2022-12-15
公開日2023-02-08
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structure and activity of botulinum neurotoxin X.
Biorxiv, 2023
4AGW
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BU of 4agw by Molmil
Discovery of a small molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromet hyl)phenyl}benzamide, GLYCEROL, ...
著者Weisberg, E, Choi, H.G, Seeliger, M, Gray, N, Griffin, J.D.
登録日2012-02-01
公開日2012-02-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of a Small-Molecule Type II Inhibitor of Wild-Type and Gatekeeper Mutants of Bcr-Abl, Pdgfralpha, Kit, and Src Kinases: Novel Type II Inhibitor of Gatekeeper Mutants.
Blood, 115, 2010
5WE4
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BU of 5we4 by Molmil
70S ribosome-EF-Tu wt complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-07
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WE6
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BU of 5we6 by Molmil
70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-07
公開日2018-04-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
5WDT
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BU of 5wdt by Molmil
70S ribosome-EF-Tu H84A complex with GppNHp
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Brown, Z, Frank, J.
登録日2017-07-06
公開日2018-04-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018

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