2PB6
| Crystal structure of PH0725 from Pyrococcus horikoshii OT3 | 分子名称: | FORMIC ACID, GLYCEROL, Probable diphthine synthase, ... | 著者 | Yamamoto, H, Taketa, M, Ono, N, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-28 | 公開日 | 2007-10-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of PH0725 from Pyrococcus horikoshii OT3 To be Published
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2P6O
| Crystal structure of TTHB049 from Thermus thermophilus HB8 | 分子名称: | Alpha-ribazole-5'-phosphate phosphatase | 著者 | Yamamoto, H, Taketa, M, Tanaka, Y, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-19 | 公開日 | 2007-09-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of TTHB049 from Thermus thermophilus HB8 To be Published
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3D5Q
| Crystal Structure of 11b-HSD1 in Complex with Triazole Inhibitor | 分子名称: | 3-[1-(4-fluorophenyl)cyclopropyl]-4-(1-methylethyl)-5-[4-(trifluoromethoxy)phenyl]-4H-1,2,4-triazole, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wang, Z, Liu, J, Sudom, A, Walker, N.P.C. | 登録日 | 2008-05-16 | 公開日 | 2008-10-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. Bioorg.Med.Chem., 16, 2008
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4P1W
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4P1N
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4RYD
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6SWA
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7JLQ
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7JLO
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7JLP
| cryo-EM structure of human ATG9A in nanodiscs | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Autophagy-related protein 9A | 著者 | Maeda, S, Otomo, T. | 登録日 | 2020-07-30 | 公開日 | 2020-10-28 | 最終更新日 | 2020-12-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure, lipid scrambling activity and role in autophagosome formation of ATG9A. Nat.Struct.Mol.Biol., 27, 2020
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2D5G
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3VX8
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1UK1
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3VU4
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8HAR
| SAH-bound C-Methyltransferase Fur6 from Streptomyces sp. KO-3988 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fur6, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Noguchi, T, Nagata, R, Tomita, T, Kuzuyama, T. | 登録日 | 2022-10-26 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Reductive biosynthesis of meroterpenoids via transient diazotization To Be Published
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5Z5S
| Crystal structure of the PPARgamma-LBD complexed with compound 13ab | 分子名称: | 3-{[6-(4-chloro-3-fluorophenoxy)-1-methyl-1H-benzimidazol-2-yl]methoxy}benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... | 著者 | Matsui, Y, Hanzawa, H. | 登録日 | 2018-01-19 | 公開日 | 2018-10-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of DS-6930, a potent selective PPAR gamma modulator. Part I: Lead identification. Bioorg. Med. Chem., 26, 2018
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5Z6S
| Crystal structure of the PPARgamma-LBD complexed with compound DS-6930 | 分子名称: | 3-[[6-(3,5-dimethylpyridin-2-yl)oxy-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid, CHLORIDE ION, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, ... | 著者 | Matsui, Y, Hanzawa, H. | 登録日 | 2018-01-25 | 公開日 | 2018-10-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of DS-6930, a potent selective PPAR gamma modulator. Part II: Lead optimization. Bioorg. Med. Chem., 26, 2018
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3WW6
| Crystal Structure of hen egg white lysozyme mutant N46D/D52S | 分子名称: | CHLORIDE ION, Lysozyme C | 著者 | Abe, Y, Kubota, M, Ito, Y, Imoto, T, Ueda, T. | 登録日 | 2014-06-17 | 公開日 | 2015-06-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme. Protein Sci., 25, 2016
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3WW5
| Crystal Structure of hen egg white lysozyme mutant N46E/D52S | 分子名称: | CHLORIDE ION, Lysozyme C | 著者 | Abe, Y, Kubota, M, Ito, Y, Imoto, T, Ueda, T. | 登録日 | 2014-06-17 | 公開日 | 2015-06-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme. Protein Sci., 25, 2016
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3W6X
| Yeast N-acetyltransferase Mpr1 in complex with CHOP | 分子名称: | (4S)-4-hydroxy-L-proline, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | 著者 | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | 登録日 | 2013-02-25 | 公開日 | 2013-08-07 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism Proc.Natl.Acad.Sci.USA, 110, 2013
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3W6S
| yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism | 分子名称: | HEXAETHYLENE GLYCOL, MAGNESIUM ION, MPR1 protein | 著者 | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | 登録日 | 2013-02-21 | 公開日 | 2013-07-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism Proc.Natl.Acad.Sci.USA, 110, 2013
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2EQQ
| Solution structure of growth-blocking peptide of the armyworm, Pseudaletia separata | 分子名称: | Growth-blocking peptide, long form | 著者 | Umetsu, Y, Aizawa, T, Kamiya, M, Kumaki, Y, Demura, M, Kawano, K. | 登録日 | 2007-03-30 | 公開日 | 2008-04-01 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | C-terminal elongation of growth-blocking peptide enhances its biological activity and micelle binding affinity J.Biol.Chem., 284, 2009
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2EQH
| Solution structure of growth-blocking peptide of the armyworm, Pseudaletia separata | 分子名称: | Growth-blocking peptide, short form | 著者 | Umetsu, Y, Aizawa, T, Kamiya, M, Kumaki, Y, Demura, M, Kawano, K. | 登録日 | 2007-03-30 | 公開日 | 2008-04-01 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | C-terminal elongation of growth-blocking peptide enhances its biological activity and micelle binding affinity J.Biol.Chem., 284, 2009
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2EQT
| Micelle-bound structure of growth-blocking peptide of the armyworm, Pseudaletia separata | 分子名称: | Growth-blocking peptide, long form | 著者 | Umetsu, Y, Aizawa, T, Kamiya, M, Kumaki, Y, Demura, M, Kawano, K. | 登録日 | 2007-03-30 | 公開日 | 2008-04-01 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | C-terminal elongation of growth-blocking peptide enhances its biological activity and micelle binding affinity J.Biol.Chem., 284, 2009
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7C3N
| Crystal structure of JAK3 in complex with Delgocitinib | 分子名称: | 3-[(3S,4R)-3-methyl-7-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrile, Tyrosine-protein kinase JAK3 | 著者 | Doi, S, Otira, T, Kikuwaka, M, Nomura, A, Noji, S, Adachi, T. | 登録日 | 2020-05-13 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders. J.Med.Chem., 63, 2020
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