5IS8
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![BU of 5is8 by Molmil](/molmil-images/mine/5is8) | Crystal structure of mouse CARM1 in complex with inhibitor SA0271 | 分子名称: | 1,2-ETHANEDIOL, 5'-{[(3S)-3-amino-3-carboxypropyl](2-chloroethyl)amino}-5'-deoxyadenosine, Histone-arginine methyltransferase CARM1, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.709 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with inhibitor SA0271 To Be Published
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5ISH
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![BU of 5ish by Molmil](/molmil-images/mine/5ish) | Crystal structure of mouse CARM1 in complex with inhibitor SA0765 | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with inhibitor SA0765 To Be Published
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5ISE
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![BU of 5ise by Molmil](/molmil-images/mine/5ise) | Crystal structure of mouse CARM1 in complex with inhibitor SA0649 | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... | 著者 | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of mouse CARM1 in complex with SAH at 1.8 Angstroms resolution To Be Published
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4C4A
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![BU of 4c4a by Molmil](/molmil-images/mine/4c4a) | Crystal structure of mouse protein arginine methyltransferase 7 in complex with SAH | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, PROTEIN ARGININE N-METHYLTRANSFERASE 7, ... | 著者 | Cura, V, Troffer-Charlier, N, Bonnefond, L, Wurtz, J.M, Cavarelli, J. | 登録日 | 2013-09-02 | 公開日 | 2014-07-02 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Insight Into Arginine Methylation by the Mouse Protein Arginine Methyltransferase 7: A Zinc Finger Freezes the Mimic of the Dimeric State Into a Single Active Site. Acta Crystallogr.,Sect.D, 70, 2014
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4C04
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![BU of 4c04 by Molmil](/molmil-images/mine/4c04) | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with inhibitor | 分子名称: | PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | 登録日 | 2013-07-31 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.576 Å) | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6. J.Struct.Biol., 191, 2015
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4C08
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![BU of 4c08 by Molmil](/molmil-images/mine/4c08) | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with CaCl2 at 1.34 Angstroms | 分子名称: | CALCIUM ION, PENTAETHYLENE GLYCOL, PROTEIN ARGININE N-METHYLTRANSFERASE 6 | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | 登録日 | 2013-07-31 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.338 Å) | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6. J.Struct.Biol., 191, 2015
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4C06
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![BU of 4c06 by Molmil](/molmil-images/mine/4c06) | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with MgCl2 | 分子名称: | MAGNESIUM ION, PROTEIN ARGININE N-METHYLTRANSFERASE 6 | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | 登録日 | 2013-07-31 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6. J.Struct.Biol., 191, 2015
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4C05
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![BU of 4c05 by Molmil](/molmil-images/mine/4c05) | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with SAH | 分子名称: | PROTEIN ARGININE N-METHYLTRANSFERASE 6, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | 登録日 | 2013-07-31 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.195 Å) | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6. J.Struct.Biol., 191, 2015
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4C07
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![BU of 4c07 by Molmil](/molmil-images/mine/4c07) | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with CaCl2 at 1.5 Angstroms | 分子名称: | CALCIUM ION, PROTEIN ARGININE N-METHYLTRANSFERASE 6 | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | 登録日 | 2013-07-31 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6. J.Struct.Biol., 191, 2015
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4C03
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![BU of 4c03 by Molmil](/molmil-images/mine/4c03) | Crystal structure of M. musculus protein arginine methyltransferase PRMT6 reduced | 分子名称: | PROTEIN ARGININE N-METHYLTRANSFERASE 6, SINEFUNGIN | 著者 | Bonnefond, L, Cura, V, Troffer-Charlier, N, Mailliot, J, Wurtz, J.M, Cavarelli, J. | 登録日 | 2013-07-31 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Functional Insights from High Resolution Structures of Mouse Protein Arginine Methyltransferase 6. J.Struct.Biol., 191, 2015
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2OQB
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![BU of 2oqb by Molmil](/molmil-images/mine/2oqb) | |
4Z9V
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![BU of 4z9v by Molmil](/molmil-images/mine/4z9v) | TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL | 分子名称: | BICARBONATE ION, Bcl-2-like protein 1,APOPTOSIS REGULATOR BCL-XL, SODIUM ION, ... | 著者 | Cura, V, Agez, M, Thebault, S, Cavarelli, J. | 登録日 | 2015-04-12 | 公開日 | 2016-02-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL. Sci Rep, 6, 2016
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7NUE
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![BU of 7nue by Molmil](/molmil-images/mine/7nue) | Crystal structure of mouse PRMT6 in complex with inhibitor EML736 | 分子名称: | Protein arginine N-methyltransferase 6, methyl 6-[5-[[~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]carbamimidoyl]amino]pentylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylate | 著者 | Bonnefond, L, Cavarelli, J. | 登録日 | 2021-03-11 | 公開日 | 2022-03-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach. J.Med.Chem., 65, 2022
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7NUD
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![BU of 7nud by Molmil](/molmil-images/mine/7nud) | Crystal structure of mouse PRMT6 in complex with inhibitor EML734 | 分子名称: | Protein arginine N-methyltransferase 6, methyl 6-[3-[[~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl]carbamimidoyl]amino]propylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylate | 著者 | Bonnefond, L, Cavarelli, J. | 登録日 | 2021-03-11 | 公開日 | 2022-03-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach. J.Med.Chem., 65, 2022
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7P2R
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![BU of 7p2r by Molmil](/molmil-images/mine/7p2r) | Crystal structure of mouse PRMT6 in complex with inhibitor EML980 | 分子名称: | Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, methyl 6-[4-[[N-[2-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl]carbamimidoyl]amino]butylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylate | 著者 | Bonnefond, L, Cavarelli, J. | 登録日 | 2021-07-06 | 公開日 | 2022-05-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach. J.Med.Chem., 65, 2022
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5FQO
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![BU of 5fqo by Molmil](/molmil-images/mine/5fqo) | |
5FQN
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![BU of 5fqn by Molmil](/molmil-images/mine/5fqn) | |