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5MLU
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BU of 5mlu by Molmil
Crystal structure of the PFV GAG CBS bound to a mononucleosome
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B, ...
著者Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P.
登録日2016-12-07
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6GHM
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BU of 6ghm by Molmil
Structure of PP1 alpha phosphatase bound to ASPP2
分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Apoptosis-stimulating of p53 protein 2, ...
著者Mouilleron, S, Bertran, T.M, Tapon, N, Zhou, Y.
登録日2018-05-08
公開日2019-02-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail.
Nat Commun, 10, 2019
5LI9
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BU of 5li9 by Molmil
Structure of a nucleotide-bound form of PKCiota core kinase domain
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ivanova, M.E, Purkiss, A.G, McDonald, N.Q.
登録日2016-07-14
公開日2016-09-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
5LXI
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BU of 5lxi by Molmil
GABARAP-L1 ATG4B LIR Complex
分子名称: 1,2-ETHANEDIOL, Cysteine protease ATG4B, DI(HYDROXYETHYL)ETHER, ...
著者Mouilleron, S, Skytte Rasmussen, M, Kumar Shrestha, B, Wirth, M, Bowitz Larsen, K, Abudu Princely, Y, Sjottem, E, Tooze, S, Lamark, T, Johansen, T, Lee, R.
登録日2016-09-21
公開日2017-02-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy, 13, 2017
5LXH
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BU of 5lxh by Molmil
GABARAP-L1 ATG4B LIR Complex
分子名称: Cysteine protease ATG4B, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1, ...
著者Mouilleron, S, Skytte Rasmussen, M, Kumar Shrestha, B, Wirth, M, Bowitz Larsen, K, Abudu Princely, Y, Sjottem, E, Tooze, S, Lamark, T, Johansen, T, Lee, R.
登録日2016-09-21
公開日2017-02-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.
Autophagy, 13, 2017
6ZYF
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BU of 6zyf by Molmil
Notum_Ghrelin complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Palmitoleoyl-protein carboxylesterase NOTUM, ...
著者Zhao, Y, Jones, E.Y.
登録日2020-07-31
公開日2021-03-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Notum deacylates octanoylated ghrelin.
Mol Metab, 49, 2021
4CAD
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BU of 4cad by Molmil
Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DODECYL-BETA-D-MALTOSIDE, ...
著者Kulkarni, K, Manolaridis, I, Dodd, R.B, Cronin, N, Ogasawara, S, Iwata, S, Barford, D.
登録日2013-10-08
公開日2013-11-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of Farnesylated Caax Protein Processing by the Intramembrane Protease Rce1
Nature, 504, 2013
6YA6
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BU of 6ya6 by Molmil
Minimal construct of Cdc7-Dbf4 bound to XL413
分子名称: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, BORIC ACID, CHLORIDE ION, ...
著者Dick, S.D, Cherepanov, P.
登録日2020-03-11
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
6YA8
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BU of 6ya8 by Molmil
Cdc7-Dbf4 bound to ADP-BeF3
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, ...
著者Dick, S.D, Cherepanov, P.
登録日2020-03-11
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
6YA7
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BU of 6ya7 by Molmil
Cdc7-Dbf4 bound to an Mcm2-S40 derived bivalent substrate
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase,Cell division cycle 7-related protein kinase, DNA replication licensing factor MCM2, ...
著者Dick, S.D, Cherepanov, P.
登録日2020-03-11
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Structure, 28, 2020
2VWF
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BU of 2vwf by Molmil
Grb2 SH3C (2)
分子名称: GRB2-ASSOCIATED-BINDING PROTEIN 2, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
著者Harkiolaki, M, Tsirka, T, Feller, S.M.
登録日2008-06-24
公開日2009-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2W10
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BU of 2w10 by Molmil
Mona SH3C in complex
分子名称: GRB2-RELATED ADAPTOR PROTEIN 2, PHOSPHATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23
著者Harkiolaki, M, Feller, S.M.
登録日2008-10-13
公開日2009-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2VVK
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BU of 2vvk by Molmil
Grb2 SH3C (1)
分子名称: GLYCEROL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
著者Harkiolaki, M, Tsirka, T, Feller, S.M.
登録日2008-06-09
公開日2009-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
2W0Z
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BU of 2w0z by Molmil
Grb2 SH3C (3)
分子名称: GRB2-ASSOCIATED-BINDING PROTEIN 2, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
著者Harkiolaki, M, Tsirka, T, Feller, S.M.
登録日2008-10-13
公開日2009-05-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17, 2009
3U23
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BU of 3u23 by Molmil
Atomic resolution crystal structure of the 2nd SH3 domain from human CD2AP (CMS) in complex with a proline-rich peptide from human RIN3
分子名称: 1,2-ETHANEDIOL, CD2-associated protein, Ras and Rab interactor 3
著者Simister, P.C, Rouka, E, Janning, M, Muniz, J.R.C, Kirsch, K.H, Knapp, S, von Delft, F, Filippakopoulos, P, Arrowsmith, C.H, Krojer, T, Edwards, A.M, Weigelt, J, Bountra, C, Feller, S.M, Structural Genomics Consortium (SGC)
登録日2011-09-30
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
J.Biol.Chem., 290, 2015
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