1R3J
 
 | | potassium channel KcsA-Fab complex in high concentration of Tl+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
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1R3I
 | | potassium channel KcsA-Fab complex in Rb+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
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1R3L
 | | potassium channel KcsA-Fab complex in Cs+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, CESIUM ION, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
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1R3K
 | | potassium channel KcsA-Fab complex in low concentration of Tl+ | | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | | 著者 | Zhou, Y, MacKinnon, R. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates
J.Mol.Biol., 333, 2003
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8W6P
 | | Crystal structure of dimeric murine SMPDL3A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid sphingomyelinase-like phosphodiesterase 3a, ... | | 著者 | Zhang, C, Liu, P, Fan, S, Hou, Y. | | 登録日 | 2023-08-29 | | 公開日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Immunity, 56, 2023
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3WJM
 | | Crystal structure of Bombyx mori Sp2/Sp3 heterohexamer | | 分子名称: | Arylphorin, Silkworm storage protein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Yuan, Y.A, Hou, Y. | | 登録日 | 2013-10-11 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of Bombyx mori arylphorins reveals a 3:3 heterohexamer with multiple papain cleavage sites
Protein Sci., 23, 2014
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6J4C
 | | Crystal structure of MarH, an epimerase for biosynthesis of Maremycins in Streptomyces, under 10 mM ZnSO4 | | 分子名称: | ACETIC ACID, Cupin superfamily protein, GLYCEROL, ... | | 著者 | Hou, Y, Liu, B, Hu, K, Zhang, R. | | 登録日 | 2019-01-08 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structural basis of the mechanism of beta-methyl epimerization by enzyme MarH.
Org.Biomol.Chem., 17, 2019
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6J4B
 | | Crystal structure of MarH, an epimerase for biosynthesis of Maremycins in Streptomyces, under 400 mM Zinc acetate | | 分子名称: | ACETIC ACID, Cupin superfamily protein, GLYCEROL, ... | | 著者 | Hou, Y, Liu, B, Hu, K, Zhang, R. | | 登録日 | 2019-01-08 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structural basis of the mechanism of beta-methyl epimerization by enzyme MarH.
Org.Biomol.Chem., 17, 2019
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3UST
 | | Structure of BmNPV ORF075 (p33) | | 分子名称: | AcMNPV orf92, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Yuan, Y.A, Hou, Y, Xia, Q. | | 登録日 | 2011-11-23 | | 公開日 | 2012-10-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of Bombyx mori nucleopolyhedrovirus ORF75 reveals a pseudo-dimer of thiol oxidase domains with a putative substrate-binding pocket
J.Gen.Virol., 93, 2012
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6J4D
 | | Crystal structure of MarH, an epimerase for biosynthesis of Maremycins in Streptomyces, under pH 4.7, without Zn | | 分子名称: | CITRATE ANION, Cupin superfamily protein, GLYCEROL | | 著者 | Hou, Y, Liu, B, Hu, K, Zhang, R. | | 登録日 | 2019-01-08 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural Basis for the Isomerization Mechanism of MarH
To Be Published
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6LUI
 | | Crystal structure of the SAMD1 WH domain and DNA complex | | 分子名称: | Atherin, DNA (5'-D(*AP*CP*CP*TP*GP*CP*GP*CP*AP*CP*CP*AP*T)-3'), DNA (5'-D(*AP*TP*GP*GP*TP*GP*CP*GP*CP*AP*GP*GP*T)-3') | | 著者 | Zhou, Y, Cao, Y, Wang, Z. | | 登録日 | 2020-01-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-07-07 | | 実験手法 | X-RAY DIFFRACTION (1.781 Å) | | 主引用文献 | The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands.
Sci Adv, 7, 2021
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6LT9
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6DCX
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7M42
 | | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989 | | 分子名称: | REGN10985 antibody Fab fragment heavy chain, REGN10985 antibody Fab fragment light chain, REGN10989 antibody Fab fragment heavy chain, ... | | 著者 | Zhou, Y, Romero Hernandez, A, Saotome, K, Franklin, M.C. | | 登録日 | 2021-03-19 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies.
Cell, 184, 2021
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3M8L
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3RIG
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2HVJ
 | | Crystal structure of KcsA-Fab-TBA complex in low K+ | | 分子名称: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, NONAN-1-OL, POTASSIUM ION, ... | | 著者 | Zhou, Y. | | 登録日 | 2006-07-28 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel.
J.Mol.Biol., 366, 2007
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2HVK
 | | crystal structure of the KcsA-Fab-TBA complex in high K+ | | 分子名称: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, Antibody Fab heavy chain, Antibody Fab light chain, ... | | 著者 | Zhou, Y. | | 登録日 | 2006-07-28 | | 公開日 | 2007-02-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel.
J.Mol.Biol., 366, 2007
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3RIY
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3U3D
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3U31
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7VO5
 | | Pimaricin type I PKS thioesterase domain (holo Pim TE) | | 分子名称: | (1R,3S,5E,7S,11R,13E,15E,17E,19E,21R,23S,24R,25S)-11,24-dimethyl-1,3,7,21,25-pentakis(oxidanyl)-10,27-dioxabicyclo[21.3.1]heptacosa-5,13,15,17,19-pentaen-9-one, ScnS4 | | 著者 | Bai, L, Zhou, Y. | | 登録日 | 2021-10-12 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain
Acs Catalysis, 12, 2022
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7VO4
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8W07
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-402 | | 分子名称: | (1R,2S,4R)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, (1S,2R,4S)-N-cyclohexyl-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.K, Nettles, K.W. | | 登録日 | 2024-02-13 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8VYX
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-410 | | 分子名称: | 4,4'-[(1S,4S,5R)-5-(3,4-dihydroquinoline-1(2H)-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2024-02-09 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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