2IHQ
| |
3BEN
| |
2K3U
| Structure of the tyrosine-sulfated C5a receptor N-terminus in complex with the immune evasion protein CHIPS. | 分子名称: | C5a anaphylatoxin chemotactic receptor 1, Chemotaxis inhibitory protein | 著者 | Ippel, J.H, Bunschoten, A, Kemmink, J, Liskamp, R. | 登録日 | 2008-05-16 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureus. J.Biol.Chem., 284, 2009
|
|
5K9A
| Sortase A from Corynebacterium diphtheriae | 分子名称: | Putative fimbrial associated sortase-like protein, SULFATE ION | 著者 | Osipiuk, J, Huang, I.-H, Ma, X, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-05-31 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking. Proc.Natl.Acad.Sci.USA, 115, 2018
|
|
5KRE
| Covalent inhibitor of LYPLAL1 | 分子名称: | (2~{R})-2-phenylpiperidine-1-carbaldehyde, Lysophospholipase-like protein 1, NITRATE ION | 著者 | Pandit, J. | 登録日 | 2016-07-07 | 公開日 | 2016-07-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. Acs Chem.Biol., 11, 2016
|
|
1MAF
| |
1MAE
| |
7SSJ
| |
7TMW
| Cryo-EM structure of the relaxin receptor RXFP1 in complex with heterotrimeric Gs | 分子名称: | Camelid antibody VHH fragment Nb35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Erlandson, S.C, Rawson, S, Kruse, A.C. | 登録日 | 2022-01-20 | 公開日 | 2023-02-15 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nat.Chem.Biol., 19, 2023
|
|
1BT7
| THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES | 分子名称: | NS3 SERINE PROTEASE, ZINC ION | 著者 | Barbato, G, Cicero, D.O, Nardi, M.C, Steinkuhler, C, Cortese, R, De Francesco, R, Bazzo, R. | 登録日 | 1998-09-01 | 公開日 | 1999-06-22 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism. J.Mol.Biol., 289, 1999
|
|
6ZUJ
| Human serine racemase holoenzyme from 20% DMSO soak (XChem crystallographic fragment screen). | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Koulouris, C.R, Bax, B.D, Roe, S.M, Atack, J.R. | 登録日 | 2020-07-23 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
|
|
6ZSP
| Human serine racemase bound to ATP and malonate. | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | 著者 | Koulouris, C.R, Bax, B.D, Roe, S.M, Atack, J.R. | 登録日 | 2020-07-16 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5, 2022
|
|
1CEG
| CEPHALOTHIN COMPLEXED WITH DD-PEPTIDASE | 分子名称: | CEPHALOTHIN GROUP, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRANSPEPTIDASE | 著者 | Knox, J.R, Kuzin, A.P. | 登録日 | 1995-01-12 | 公開日 | 1996-10-14 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry, 34, 1995
|
|
1CEF
| CEFOTAXIME COMPLEXED WITH THE STREPTOMYCES R61 DD-PEPTIDASE | 分子名称: | CEFOTAXIME, C3' cleaved, open, ... | 著者 | Knox, J.R, Kuzin, A.P. | 登録日 | 1995-01-12 | 公開日 | 1996-10-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Binding of cephalothin and cefotaxime to D-ala-D-ala-peptidase reveals a functional basis of a natural mutation in a low-affinity penicillin-binding protein and in extended-spectrum beta-lactamases. Biochemistry, 34, 1995
|
|
1L34
| |
2WJO
| |
8QZG
| 1,3 L,D-transpeptidase from Gluconobacter oxydans | 分子名称: | CHLORIDE ION, SODIUM ION, YkuD domain-containing protein | 著者 | ter Beek, J, Berntsson, R.P. | 登録日 | 2023-10-27 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha- and Betaproteobacteria. Nat Commun, 15, 2024
|
|
3EZX
| |
1L21
| |
1L24
| |
1L18
| |
7R7H
| Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors | 分子名称: | 3C-like proteinase, N-[(2S)-1-({(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | 著者 | Khan, M.B, Lu, J, Young, H.S, Lemieux, M.J. | 登録日 | 2021-06-24 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitors. Rsc Med Chem, 12, 2021
|
|
1L33
| |
1L17
| |
1L19
| |