2BE7
| Crystal structure of the unliganded (T-state) aspartate transcarbamoylase of the psychrophilic bacterium Moritella profunda | 分子名称: | Aspartate Carbamoyltransferase Catalytic Chain, Aspartate Carbamoyltransferase Regulatory Chain, SULFATE ION, ... | 著者 | De Vos, D, Savvides, S.N, Van Beeumen, J. | 登録日 | 2005-10-23 | 公開日 | 2006-10-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural investigation of cold activity and regulation of aspartate carbamoyltransferase from the extreme psychrophilic bacterium Moritella profunda. J.Mol.Biol., 365, 2007
|
|
2GJK
| Structural and functional insights into the human Upf1 helicase core | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Regulator of nonsense transcripts 1 | 著者 | Cheng, Z, Muhlrad, D, Parker, R, Song, H. | 登録日 | 2006-03-31 | 公開日 | 2007-01-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and functional insights into the human Upf1 helicase core Embo J., 26, 2007
|
|
2GOU
| Structure of wild type, oxidized SYE1, an OYE homologue from S. oneidensis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, FLAVIN MONONUCLEOTIDE, ... | 著者 | Savvides, S.N, van den Hemel, D. | 登録日 | 2006-04-14 | 公開日 | 2006-07-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Ligand-induced conformational changes in the capping subdomain of a bacterial old yellow enzyme homologue and conserved sequence fingerprints provide new insights into substrate binding. J.Biol.Chem., 281, 2006
|
|
2GQA
| |
2GUZ
| Structure of the Tim14-Tim16 complex of the mitochondrial protein import motor | 分子名称: | CITRATE ANION, Mitochondrial import inner membrane translocase subunit TIM14, Mitochondrial import inner membrane translocase subunit TIM16 | 著者 | Mokranjac, D, Bourenkov, G, Hell, K, Neupert, W, Groll, M. | 登録日 | 2006-05-02 | 公開日 | 2006-10-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor. Embo J., 25, 2006
|
|
2H16
| Structure of human ADP-ribosylation factor-like 5 (ARL5) | 分子名称: | ADP-ribosylation factor-like protein 5A, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION | 著者 | Rabeh, W.M, Tempel, W, Yaniw, D, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2006-05-16 | 公開日 | 2006-06-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of human ADP-ribosylation factor-like 5 (ARL5) To be Published
|
|
2GZO
| NMR structure of UPF0301 PROTEIN SO3346 from Shewanella oneidensis: Northeast Structural Genomics Consortium target SOR39 | 分子名称: | UPF0301 protein SO3346 | 著者 | Singarapu, K.K, Liu, G, Eletsky, A, Xu, D, Sukumaran, D.K, Mei, J, Xiao, R, Cunningham, K, Ma, L.C, Ritu, S, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-05-11 | 公開日 | 2006-06-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of UPF0301 PROTEIN SO3346 from Shewanella oneidensis: Northeast Structural Genomics Consortium target SOR39 To be Published
|
|
2H85
| Crystal Structure of Nsp 15 from SARS | 分子名称: | Putative orf1ab polyprotein | 著者 | Ricagno, S, Egloff, M.P, Ulferts, R, Coutard, B, Nurizzo, D, Campanacci, V, Cambillau, C, Ziebuhr, J, Canard, B. | 登録日 | 2006-06-06 | 公開日 | 2006-08-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2HBH
| Crystal structure of Vitamin D nuclear receptor ligand binding domain bound to a locked side-chain analog of calcitriol and SRC-1 peptide | 分子名称: | 1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z), ... | 著者 | Rochel, N, Hourai, S, Moras, D. | 登録日 | 2006-06-14 | 公開日 | 2007-05-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol Arch.Biochem.Biophys., 460, 2007
|
|
2HC4
| Crystal structure of the LBD of VDR of Danio rerio in complex with calcitriol | 分子名称: | 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, SRC-1 from Nuclear receptor coactivator 1, Vitamin D receptor | 著者 | Ciesielski, F, Rochel, N, Moras, D. | 登録日 | 2006-06-15 | 公開日 | 2007-05-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation J.Steroid Biochem.Mol.Biol., 103, 2007
|
|
2HCD
| Crystal structure of the ligand binding domain of the Vitamin D nuclear receptor in complex with Gemini and a coactivator peptide | 分子名称: | 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E), ... | 著者 | Ciesielski, F, Rochel, N, Moras, D. | 登録日 | 2006-06-16 | 公開日 | 2007-05-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation J.Steroid Biochem.Mol.Biol., 103, 2007
|
|
2GMO
| NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2 | 分子名称: | Polymerase basic protein 2 | 著者 | Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J. | 登録日 | 2006-04-07 | 公開日 | 2007-02-27 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat.Struct.Mol.Biol., 14, 2007
|
|
2GK6
| Structural and Functional insights into the human Upf1 helicase core | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Cheng, Z, Muhlrad, D, Parker, R, Song, H. | 登録日 | 2006-03-31 | 公開日 | 2007-01-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional insights into the human Upf1 helicase core Embo J., 26, 2007
|
|
2GW8
| Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 resolution | 分子名称: | PII signal transduction protein | 著者 | Nichols, C.E, Sainsbury, S, Berrow, N.S, Alderton, D, Stammers, D.K, Owens, R.J, Oxford Protein Production Facility (OPPF) | 登録日 | 2006-05-04 | 公開日 | 2006-06-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of the P(II) signal transduction protein of Neisseria meningitidis at 1.85 A resolution. Acta Crystallogr.,Sect.F, 62, 2006
|
|
2GSO
| Structure of Xac Nucleotide Pyrophosphatase/Phosphodiesterase in Complex with Vanadate | 分子名称: | VANADATE ION, ZINC ION, phosphodiesterase-nucleotide pyrophosphatase | 著者 | Zalatan, J.G, Fenn, T.D, Brunger, A.T, Herschlag, D. | 登録日 | 2006-04-26 | 公開日 | 2006-08-01 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution Biochemistry, 45, 2006
|
|
2H3S
| cis-Azobenzene-avian pancreatic polypeptide bound to DPC micelles | 分子名称: | (3-{(Z)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone | 著者 | Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D. | 登録日 | 2006-05-23 | 公開日 | 2006-09-12 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide Angew.Chem.Int.Ed.Engl., 45, 2006
|
|
2HAF
| Crystal structure of a putative translation repressor from Vibrio cholerae | 分子名称: | Putative translation repressor | 著者 | Sugadev, R, Seetharaman, J, Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2006-06-12 | 公開日 | 2006-07-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Crystal structure of a putative translation repressor from Vibrio cholerae To be Published
|
|
2HAM
| Crystal structure of VDR LBD complexed to 2alpha-propyl-calcitriol | 分子名称: | 2ALPHA-PROPYL-1ALPHA,25-DIHYDROXYVITAMIN D3, Vitamin D3 receptor | 著者 | Hourai, S, Rochel, N, Moras, D. | 登録日 | 2006-06-13 | 公開日 | 2006-08-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing a Water Channel near the A-Ring of Receptor-Bound 1alpha,25-Dihydroxyvitamin D3 with Selected 2alpha-Substituted Analogues J.Med.Chem., 49, 2006
|
|
2KQC
| Second PBZ domain of human APLF protein | 分子名称: | Aprataxin and PNK-like factor, ZINC ION | 著者 | Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J. | 登録日 | 2009-11-04 | 公開日 | 2010-01-19 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose). Nat.Struct.Mol.Biol., 17, 2010
|
|
2KQB
| First PBZ domain of human APLF protein | 分子名称: | Aprataxin and PNK-like factor, ZINC ION | 著者 | Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J. | 登録日 | 2009-11-04 | 公開日 | 2010-01-19 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose). Nat.Struct.Mol.Biol., 17, 2010
|
|
2M6T
| NMR solution structure ensemble of 3-4D mutant domain 11 IGF2R | 分子名称: | Insulin-like growth factor 2 receptor variant | 著者 | Strickland, M, Williams, C, Richards, E, Minnall, L, Crump, M.P, Frago, S, Hughes, J, Garner, L, Hoppe, H, Rezgui, D, Zaccheo, O.J, Prince, S.N, Hassan, A.B, Whittaker, S. | 登録日 | 2013-04-09 | 公開日 | 2014-10-15 | 最終更新日 | 2016-06-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4X2G
| Selection of fragments for kinase inhibitor design: decoration is key | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[(4-aminophenyl)amino]pyrido[2,3-d]pyrimidin-5(6H)-one, SULFATE ION, ... | 著者 | Czodrowski, P, Hoelzemann, G, Barnickel, G, Greiner, H, Musil, D. | 登録日 | 2014-11-26 | 公開日 | 2015-08-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Selection of fragments for kinase inhibitor design: decoration is key. J.Med.Chem., 58, 2015
|
|
4X3C
| |
4WX7
| Crystal structure of adenovirus 8 protease with a nitrile inhibitor | 分子名称: | 3-[2-(3,5-dichlorophenyl)-2-methylpropanoyl]-N-(2-{[(2Z)-2-iminoethyl]amino}-2-oxoethyl)-4-methoxybenzamide, PVI, Protease | 著者 | Grosche, P, Sirockin, F, Mac Sweeney, A, Ramage, P, Erbel, P, Melkko, S, Bernardi, A, Hughes, N, Ellis, D, Combrink, K, Jarousse, N, Altmann, E. | 登録日 | 2014-11-13 | 公開日 | 2015-01-14 | 最終更新日 | 2015-01-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based design and optimization of potent inhibitors of the adenoviral protease. Bioorg.Med.Chem.Lett., 25, 2015
|
|
6CY7
| Human Stimulator of Interferon Genes | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GLYCEROL, IMIDAZOLE, ... | 著者 | Fernandez, D, Li, L, Ergun, S.L. | 登録日 | 2018-04-04 | 公開日 | 2019-03-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition. Cell, 178, 2019
|
|