8XVA
| Human TOM complex with whole Tom20 | 分子名称: | Mitochondrial import receptor subunit TOM20 homolog, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ... | 著者 | Tian, X.Y, Su, J.Y, Sui, S.F. | 登録日 | 2024-01-14 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (5.92 Å) | 主引用文献 | Structure of the intact Tom20 receptor in the human translocase of the outer membrane complex. Pnas Nexus, 3, 2024
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8JZN
| Structure of a fungal 1,3-beta-glucan synthase | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, C, You, Z, Chen, D, Hang, J, Wang, Z, Meng, J, Wang, L, Zhao, P, Qiao, J, Yun, C, Bai, L. | 登録日 | 2023-07-05 | 公開日 | 2023-10-04 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | 主引用文献 | Structure of a fungal 1,3-beta-glucan synthase. Sci Adv, 9, 2023
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3RDY
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8ISK
| Pr conformer of Zea mays phytochrome A1 - ZmphyA1-Pr | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | 登録日 | 2023-03-20 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
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8ISJ
| Pr conformer of Arabidopsis thaliana phytochrome A - AtphyA-Pr | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | 登録日 | 2023-03-20 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
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8ISI
| Photochromobilin-free form of Arabidopsis thaliana phytochrome A - apo-AtphyA | 分子名称: | Phytochrome A | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | 登録日 | 2023-03-20 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
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7MY2
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7MY3
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3RDZ
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3NBP
| HIV-1 reverse transcriptase with aminopyrimidine inhibitor 2 | 分子名称: | 4-(4-{[4-(4-cyano-2,6-dimethylphenoxy)pyrimidin-2-yl]amino}piperidin-1-yl)benzenesulfonamide, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... | 著者 | Harris, S.F, Villasenor, A.G. | 登録日 | 2010-06-03 | 公開日 | 2010-08-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Bioorg.Med.Chem.Lett., 20, 2010
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8Q6T
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4NSC
| Crystal Structure of CBARA1 in the Apo-form | 分子名称: | Calcium uptake protein 1, mitochondrial | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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8SLR
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1QUI
| PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 137 REPLACED BY GLY COMPLEX WITH BROMINE AND PHOSPHATE | 分子名称: | BROMIDE ION, PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN | 著者 | Yao, N, Choudhary, A, Ledvina, P.S, Quiocho, F.A. | 登録日 | 1995-11-11 | 公開日 | 1996-07-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Modulation of a salt link does not affect binding of phosphate to its specific active transport receptor. Biochemistry, 35, 1996
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4NSD
| Crystal Structure of CBARA1 in the Ca2+ Binding Form | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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1QUJ
| PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 137 REPLACED BY GLY COMPLEX WITH CHLORINE AND PHOSPHATE | 分子名称: | CHLORIDE ION, PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN | 著者 | Yao, N, Choudhary, A, Ledvina, P.S, Quiocho, F.A. | 登録日 | 1995-11-11 | 公開日 | 1996-07-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Modulation of a salt link does not affect binding of phosphate to its specific active transport receptor. Biochemistry, 35, 1996
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1QUL
| PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 137 REPLACED BY THR COMPLEX WITH CHLORINE AND PHOSPHATE | 分子名称: | CHLORIDE ION, PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN | 著者 | Yao, N, Choudhary, A, Ledvina, P.S, Quiocho, F.A. | 登録日 | 1995-11-11 | 公開日 | 1996-07-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Modulation of a salt link does not affect binding of phosphate to its specific active transport receptor. Biochemistry, 35, 1996
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1QUK
| PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 137 REPLACED BY ASN COMPLEX WITH PHOSPHATE | 分子名称: | PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN | 著者 | Yao, N, Choudhary, A, Ledvina, P.S, Quiocho, F.A. | 登録日 | 1995-11-11 | 公開日 | 1996-07-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Modulation of a salt link does not affect binding of phosphate to its specific active transport receptor. Biochemistry, 35, 1996
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8XN7
| Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f | 分子名称: | 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1 | 著者 | Huang, W.X, Liu, R, Ding, K. | 登録日 | 2023-12-29 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors. Eur.J.Med.Chem., 269, 2024
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6W44
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6W45
| Crystal structure of HAO1 in complex with biaryl acid inhibitor - compound 3 | 分子名称: | 2-chloranyl-4-[2-[[(6-chloranyl-1~{H}-indol-2-yl)carbonyl-methyl-amino]methyl]-5-fluoranyl-phenyl]benzoic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1 | 著者 | Ferguson, A.D. | 登録日 | 2020-03-10 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. J.Med.Chem., 64, 2021
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6W4C
| Crystal structure of HAO1 in complex with indazole acid inhibitor - compound 5 | 分子名称: | 5-[[3-[3-(dimethylamino)-1,2,4-oxadiazol-5-yl]-2-oxidanyl-phenyl]methylamino]-2~{H}-indazole-3-carboxylic acid, FLAVIN MONONUCLEOTIDE, Hydroxyacid oxidase 1 | 著者 | Ferguson, A.D. | 登録日 | 2020-03-10 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening. J.Med.Chem., 64, 2021
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6XP9
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8WE7
| Human L-type voltage-gated calcium channel Cav1.2 in the presence of calciseptine at 3.2 Angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gao, S, Yao, X, Yan, N. | 登録日 | 2023-09-17 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for human Ca v 1.2 inhibition by multiple drugs and the neurotoxin calciseptine. Cell, 186, 2023
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8WE6
| Human L-type voltage-gated calcium channel Cav1.2 at 2.9 Angstrom resolution | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gao, S, Yao, X, Yan, N. | 登録日 | 2023-09-17 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for human Ca v 1.2 inhibition by multiple drugs and the neurotoxin calciseptine. Cell, 186, 2023
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