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3BDW
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Human CD94/NKG2A
分子名称: NKG2-A/NKG2-B type II integral membrane protein, Natural killer cells antigen CD94
著者Sullivan, L.C, Clements, C.S.
登録日2007-11-15
公開日2008-01-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Heterodimeric Assembly of the CD94-NKG2 Receptor Family and Implications for Human Leukocyte Antigen-E Recognition
Immunity, 27, 2007
3ZVU
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BU of 3zvu by Molmil
Structure of the PYR1 His60Pro mutant in complex with the HAB1 phosphatase and Abscisic acid
分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABSCISIC ACID RECEPTOR PYR1, MANGANESE (II) ION, ...
著者Betz, K, Dupeux, F, Santiago, J, Rodriguez, P.L, Marquez, J.A.
登録日2011-07-27
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Thermodynamic Switch Modulates Abscisic Acid Receptor Sensitivity.
Embo J., 30, 2011
6FX7
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BU of 6fx7 by Molmil
Crystal structure of in vitro evolved Af1521
分子名称: [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, [Protein ADP-ribosylglutamate] hydrolase AF_1521
著者Karlberg, T, Thorsell, A.G, Nowak, K, Hottiger, M.O, Schuler, H.
登録日2018-03-08
公開日2019-09-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins.
Nat Commun, 11, 2020
6N3R
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BU of 6n3r by Molmil
Sheep Galectin-11 (LGALS11) complex with galactose
分子名称: Galectin, beta-D-galactopyranose
著者Beddoe, T.C, Sakthivel, D.
登録日2018-11-16
公開日2020-05-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Sheep Galectin-11 (LGALS11) complex with galactose
To be Published
3HUJ
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Crystal structure of human CD1d-alpha-Galactosylceramide in complex with semi-invariant NKT cell receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, MAGNESIUM ION, ...
著者Pang, S.S.
登録日2009-06-14
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors
Immunity, 31, 2009
4I4W
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Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Wooldridge, L, Cole, D.K.
登録日2012-11-28
公開日2013-01-02
最終更新日2015-11-25
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood, 121, 2013
3HMV
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Catalytic domain of human phosphodiesterase 4B2B in complex with a tetrahydrobenzothiophene inhibitor
分子名称: (6S)-6-methyl-2-{[(2-nitrophenyl)carbonyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, GLYCEROL, MAGNESIUM ION, ...
著者Somers, D.O, Neu, M.
登録日2009-05-29
公開日2010-06-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode
Bioorg.Med.Chem., 17, 2009
6GSS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH GLUTATHIONE
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE P1-1
著者Oakley, A, Parker, M.
登録日1997-08-13
公開日1998-09-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
5N29
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An improved model of the Trypanosoma brucei CTP synthase glutaminase domain:acivicin complex.
分子名称: CHLORIDE ION, CTP synthase
著者de Souza, J, Dawson, A, Hunter, W.
登録日2017-02-07
公開日2017-04-05
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An Improved Model of the Trypanosoma brucei CTP Synthetase Glutaminase Domain-Acivicin Complex.
ChemMedChem, 12, 2017
6XQA
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BU of 6xqa by Molmil
Crystal Structure of HLA A*2402 in complex with TYQWVLKNL, an 9-mer epitope from Influenza B virus
分子名称: Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ...
著者Nguyen, A.T, Szeto, C, Gras, S.
登録日2020-07-09
公開日2021-04-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Nat Commun, 12, 2021
6C3R
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Cricket paralysis virus RNAi suppressor protein CrPV-1A
分子名称: Cricket paralysis virus 1A protein
著者Nayak, A, Kim, D.Y, Andino, R, Gross, J.
登録日2018-01-10
公開日2018-10-17
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.
Cell Host Microbe, 24, 2018
2G3O
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The 2.1A crystal structure of copGFP
分子名称: green fluorescent protein 2
著者Wilmann, P.G.
登録日2006-02-20
公開日2006-08-15
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The 2.1A crystal structure of copGFP, a representative member of the copepod clade within the green fluorescent protein superfamily
J.Mol.Biol., 359, 2006
2JVB
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BU of 2jvb by Molmil
Solution Structure of Catalytic Domain of yDcp2
分子名称: mRNA-decapping enzyme subunit 2
著者Deshmukh, M, Gross, J.
登録日2007-09-16
公開日2008-03-04
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献mRNA Decapping Is Promoted by an RNA-Binding Channel in Dcp2.
Mol.Cell, 29, 2008
5N1Y
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BU of 5n1y by Molmil
HLA-A02 carrying MVWGPDPLYV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
登録日2017-02-06
公開日2017-02-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J. Clin. Invest., 126, 2016
2DUT
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BU of 2dut by Molmil
Crystal structure of a M-loop deletion variant of MENT in the native conformation
分子名称: Heterochromatin-associated protein MENT
著者Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A.
登録日2006-07-26
公開日2006-08-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation
Embo J., 25, 2006
3EYH
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BU of 3eyh by Molmil
Crystal structures of JAK1 and JAK2 inhibitor complexes
分子名称: 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Tyrosine-protein kinase
著者Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E.
登録日2008-10-20
公開日2009-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
10GS
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BU of 10gs by Molmil
HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH TER117
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE P1-1, L-gamma-glutamyl-S-benzyl-N-[(S)-carboxy(phenyl)methyl]-L-cysteinamide
著者Oakley, A, Parker, M.
登録日1997-08-14
公開日1998-09-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution.
J.Mol.Biol., 274, 1997
2EYR
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A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
分子名称: NKT12
著者Kjer-Nielsen, L, Borg, N.A.
登録日2005-11-09
公開日2006-03-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
J.Exp.Med., 203, 2006
2EYS
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A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
分子名称: ACETIC ACID, NKT15
著者Kjer-Nielsen, L, Borg, N.A.
登録日2005-11-09
公開日2006-03-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
J.Exp.Med., 203, 2006
3EYG
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BU of 3eyg by Molmil
Crystal structures of JAK1 and JAK2 inhibitor complexes
分子名称: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase
著者Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E.
登録日2008-10-20
公開日2009-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
2FZ3
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The role of T cell receptor alpha genes in directing human MHC restriction
分子名称: 11-mer peptide from Epstein-Barr nuclear antigen 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Miles, J.J, Borg, N.A.
登録日2006-02-09
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.
J Immunol., 177, 2006
2EYT
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A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
分子名称: NKT15
著者Kjer-Nielsen, L, Borg, N.A.
登録日2005-11-09
公開日2006-03-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition
J.Exp.Med., 203, 2006
2FYY
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The role of T cell receptor alpha genes in directing human MHC restriction
分子名称: 11-mer peptide from Epstein-Barr nuclear antigen 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Miles, J.J, Borg, N.A.
登録日2006-02-08
公開日2006-12-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.
J Immunol., 177, 2006
4K55
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Structure of the extracellular domain of butyrophilin BTN3A1 in complex with (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP)
分子名称: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, Butyrophilin subfamily 3 member A1
著者Kumar, A, Mori, L, De Libero, G.
登録日2013-04-13
公開日2013-07-24
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Butyrophilin 3A1 binds phosphorylated antigens and stimulates human gamma delta T cells.
Nat.Immunol., 14, 2013
4JKW
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Structure of the extracellular domain of butyrophilin BTN3A1 in complex with Isopentenyl pyrophosphate (IPP)
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Butyrophilin subfamily 3 member A1
著者Kumar, A, Mori, L, De Libero, G.
登録日2013-03-12
公開日2013-07-24
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Butyrophilin 3A1 binds phosphorylated antigens and stimulates human gamma delta T cells.
Nat.Immunol., 14, 2013

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