1VHK
| |
1VH2
| |
1VH9
| |
3BZ3
| |
3V81
| Crystal structure of HIV-1 reverse transcriptase (RT) with DNA and the nonnucleoside inhibitor nevirapine | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(ATM))-3'), DNA (5'-D(*AP*TP*GP*GP*AP*AP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ... | 著者 | Das, K, Martinez, S.E, Arnold, E. | 登録日 | 2011-12-22 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8503 Å) | 主引用文献 | HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism. Nat.Struct.Mol.Biol., 19, 2012
|
|
6HAQ
| AFGH61B WILD-TYPE COPPER LOADED | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, COPPER (II) ION, ... | 著者 | Lo Leggio, L, Poulsen, J.C.N, Weihe, C.D. | 登録日 | 2018-08-08 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant. Carbohydr. Res., 469, 2018
|
|
6HA5
| AFGH61B L90V/D131S/M134L/A141W VARIANT | 分子名称: | ACETATE ION, COPPER (II) ION, Endoglucanase, ... | 著者 | Lo Leggio, L, Poulsen, J.C.N. | 登録日 | 2018-08-07 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant. Carbohydr. Res., 469, 2018
|
|
6H1Z
| AFGH61B WILD-TYPE | 分子名称: | ACETATE ION, COPPER (II) ION, Endoglucanase, ... | 著者 | Lo Leggio, L, Poulsen, J.C.N. | 登録日 | 2018-07-12 | 公開日 | 2018-08-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant. Carbohydr. Res., 469, 2018
|
|
6DKJ
| human GIPR ECD and Fab complex | 分子名称: | 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... | 著者 | Min, X, Wang, Z. | 登録日 | 2018-05-29 | 公開日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models. Sci Transl Med, 10, 2018
|
|
5I2T
| |
3MVM
| P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V | 分子名称: | 4-{[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14 | 著者 | Sack, J.S. | 登録日 | 2010-05-04 | 公開日 | 2010-10-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38? Map Kinase Inhibitor for the Treatment of Inflammatory Diseases J.Med.Chem., 53, 2010
|
|
3MVL
| P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7K | 分子名称: | 4-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14 | 著者 | Sack, J.S. | 登録日 | 2010-05-04 | 公開日 | 2010-10-13 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38 Map Kinase Inhibitor for the Treatment of Inflammatory Diseases J.Med.Chem., 53, 2010
|
|
5E06
| |
5E05
| |
5E04
| |
6DND
| Crystal structure of wild-type (WT) human Glutamate oxaloacetate transaminase 1 (GOT1) | 分子名称: | Aspartate aminotransferase, cytoplasmic, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | 登録日 | 2018-06-06 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry, 57, 2018
|
|
6DNB
| Crystal structure of T110A:S256A mutant human Glutamate oxaloacetate transaminase 1 (GOT1) | 分子名称: | Aspartate aminotransferase, cytoplasmic, GLYCEROL, ... | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | 登録日 | 2018-06-06 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry, 57, 2018
|
|
6DNA
| Crystal structure of T110A mutant human Glutamate oxaloacetate transaminase 1 (GOT1) | 分子名称: | Aspartate aminotransferase, cytoplasmic, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | 登録日 | 2018-06-06 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry, 57, 2018
|
|
6SHB
| Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 1, in the presence of ssDNA | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | 著者 | Sofos, N, Montoya, G, Stella, S. | 登録日 | 2019-08-06 | 公開日 | 2020-07-08 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas. Mol.Cell, 79, 2020
|
|
6S8E
| Cryo-EM structure of the type III-B Cmr-beta complex bound to non-cognate target RNA | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | 著者 | Sofos, N, Montoya, G, Stella, S. | 登録日 | 2019-07-09 | 公開日 | 2020-07-08 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas. Mol.Cell, 79, 2020
|
|
6SH8
| Cryo-EM structure of the Type III-B Cmr-beta bound to cognate target RNA and AMPPnP, state 2, in the presence of ssDNA | 分子名称: | CRISPR-associated RAMP protein, Cmr4 family, Cmr6 family, ... | 著者 | Sofos, N, Montoya, G, Stella, S. | 登録日 | 2019-08-06 | 公開日 | 2020-07-08 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas. Mol.Cell, 79, 2020
|
|
6A50
| structure of benzoylformate decarboxylases in complex with cofactor TPP | 分子名称: | MAGNESIUM ION, THIAMINE DIPHOSPHATE, benzoylformate decarboxylases | 著者 | Guo, Y, Wang, S, Nie, Y, Li, S. | 登録日 | 2018-06-21 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Synthetic Pathway for Acetyl-Coenzyme A Biosynthesis Nat Commun, 2019
|
|
7E8O
| |
7E8K
| |
7E8J
| |