7KJW
| Structure of HIV-1 reverse transcriptase initiation complex core with efavirenz | 分子名称: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 viral RNA fragment, MAGNESIUM ION, ... | 著者 | Ha, B, Larsen, K.P, Zhang, J, Fu, Z, Montabana, E, Jackson, L.N, Chen, D.H, Puglisi, E.V. | 登録日 | 2020-10-26 | 公開日 | 2021-03-17 | 最終更新日 | 2021-05-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs. Nat Commun, 12, 2021
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7XF3
| The structure of HLA-B*1501/BM58-66AF9 | 分子名称: | 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen | 著者 | Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L. | 登録日 | 2022-03-31 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape. J Immunol., 210, 2023
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7DJZ
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ... | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2020-11-22 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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7DR8
| Crystal structure of MERS-CoV 3CL protease in spacegroup P212121 | 分子名称: | 3C-like proteinase | 著者 | Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J. | 登録日 | 2020-12-26 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.338149 Å) | 主引用文献 | Crystal structure of MERS-CoV 3CL protease in spacegroup P212121 To Be Published
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7DPM
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2020-12-20 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | 主引用文献 | Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV. Mabs, 13, 2021
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7N97
| State 2 of TcdB and FZD2 at pH5 | 分子名称: | Frizzled-2, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-17 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structural Basis for Receptor Recognition of the Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N8X
| Partial C. difficile TcdB and CSPG4 fragment | 分子名称: | Chondroitin sulfate proteoglycan 4, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-16 | 公開日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N9Q
| State 3 of TcdB and FZD2 at pH5 | 分子名称: | Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7DRA
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7N9S
| TcdB and frizzled-2 CRD complex | 分子名称: | Frizzled-2, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N9R
| state 4 of TcdB and FZD2 at pH5 | 分子名称: | Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N9Y
| Full-length TcdB and CSPG4 (401-560) complex | 分子名称: | Chondroitin sulfate proteoglycan 4, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-18 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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7N95
| state 1 of TcdB and FZD2 at pH5 | 分子名称: | Frizzled-2, Toxin B | 著者 | Jiang, M, Zhang, J. | 登録日 | 2021-06-16 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
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8TS1
| Cryo-EM structure of human MRS2 with Mg2+ | 分子名称: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial, ... | 著者 | He, Z, Mount, J.W, Zhang, J, Yuan, P. | 登録日 | 2023-08-10 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Human mitochondrial MRS2 is a Ca2+-regulated nonselective cation channel To Be Published
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8TS3
| Cryo-EM structure of human MRS2 with Ca2+ | 分子名称: | CALCIUM ION, Magnesium transporter MRS2 homolog, mitochondrial, ... | 著者 | He, Z, Mount, J.W, Zhang, J, Yuan, P. | 登録日 | 2023-08-10 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Human mitochondrial MRS2 is a Ca2+-regulated nonselective cation channel To Be Published
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8TS2
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7X68
| CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone | 分子名称: | (3aR,5S,8R,8aR,9aR)-5,8a-dimethyl-3-methylidene-8-oxidanyl-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one, Dihydropyrimidinase-related protein 2, SODIUM ION | 著者 | Zhang, S.D, Ma, Y.F, Zhang, J. | 登録日 | 2022-03-06 | 公開日 | 2022-05-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone To Be Published
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7Y78
| Crystal structure of Cry78Aa | 分子名称: | 1,2-ETHANEDIOL, AMMONIUM ION, Toxin | 著者 | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | 登録日 | 2022-06-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7Y79
| Crystal structure of Cry78Aa | 分子名称: | Toxin | 著者 | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | 登録日 | 2022-06-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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8J2P
| Crystal structure of PML B-box2 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Zhou, C, Zang, N, Zhang, J. | 登録日 | 2023-04-15 | 公開日 | 2023-09-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function. Cancer Discov, 13, 2023
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8J25
| Crystal structure of PML B-box2 mutant | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Zhou, C, Zang, N, Zhang, J. | 登録日 | 2023-04-14 | 公開日 | 2023-09-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function. Cancer Discov, 13, 2023
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7YRZ
| Crystal structure of HCoV 229E main protease in complex with PF07321332 | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase | 著者 | Zhou, Y.R, Zeng, P, Zhou, X.L, Lin, C, Zhang, J, Yin, X.S, Li, J. | 登録日 | 2022-08-11 | 公開日 | 2023-08-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structural basis of main proteases of HCoV-229E bound to inhibitor PF-07304814 and PF-07321332. Biochem.Biophys.Res.Commun., 657, 2023
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7WQH
| Crystal structure of HCoV-NL63 main protease with PF07304814 | 分子名称: | 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate | 著者 | Zhong, F.L, Zhou, X.L, Lin, C, Zeng, P, Li, J, Zhang, J. | 登録日 | 2022-01-25 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814 J.Mol.Biol., 434, 2022
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7WQJ
| Crystal structure of MERS main protease in complex with PF07304814 | 分子名称: | 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate | 著者 | Lin, C, Zhang, J, Li, J. | 登録日 | 2022-01-25 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814 J.Mol.Biol., 434, 2022
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7XB3
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