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8T9D
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BU of 8t9d by Molmil
CryoEM structure of TR-TRAP
分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
著者Zhao, H, Asturias, F.
登録日2023-06-23
公開日2024-07-03
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (4.66 Å)
主引用文献An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Mol.Cell, 84, 2024
5J5D
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BU of 5j5d by Molmil
Crystal structure of Dihydrodipicolinate Synthase from Mycobacterium tuberculosis in complex with alpha-ketopimelic acid
分子名称: 2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase, SODIUM ION
著者Navratna, V, Gopal, B.
登録日2016-04-02
公開日2016-08-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues
Sci Rep, 6, 2016
7RGG
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BU of 7rgg by Molmil
Room temperature serial crystal structure of Glutaminase C in complex with inhibitor BPTES
分子名称: Glutaminase kidney isoform, mitochondrial 68 kDa chain, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
著者Milano, S.K, Finke, A, Cerione, R.A.
登録日2021-07-15
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
J.Biol.Chem., 298, 2022
7REN
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BU of 7ren by Molmil
Room temperature serial crystal structure of Glutaminase C in complex with inhibitor UPGL-00004
分子名称: 2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}amino)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide, Glutaminase kidney isoform, mitochondrial
著者Milano, S.K, Finke, A, Cerione, R.A.
登録日2021-07-13
公開日2022-05-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
J.Biol.Chem., 298, 2022
3V00
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BU of 3v00 by Molmil
Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(t) subunit alpha-1/ Guanine nucleotide-binding protein G(i) subunit alpha-1 chimeric protein
著者Singh, G, Cerione, R.A.
登録日2011-12-07
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A constitutively active G-alpha subunit provide insights into the mechanism of G protein activation
Biochemistry, 51, 2012
1A19
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BU of 1a19 by Molmil
BARSTAR (FREE), C82A MUTANT
分子名称: BARSTAR
著者Ratnaparkhi, G.S, Varadarajan, R.
登録日1997-12-25
公開日1998-04-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Discrepancies between the NMR and X-ray structures of uncomplexed barstar: analysis suggests that packing densities of protein structures determined by NMR are unreliable.
Biochemistry, 37, 1998
6ULA
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BU of 6ula by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00012
分子名称: 2-cyclopropyl-N-{5-[4-({5-[(cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide, Glutaminase kidney isoform, mitochondrial
著者Huang, Q, Cerione, R.A.
登録日2019-10-07
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00030
To Be Published
6UL9
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BU of 6ul9 by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00023
分子名称: 2-phenyl-N-{5-[(1-{5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}azetidin-3-yl)oxy]-1,3,4-thiadiazol-2-yl}acetamide, Glutaminase kidney isoform, mitochondrial
著者Huang, Q.Q, Cerione, R.A.
登録日2019-10-07
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00012
To Be Published
6UJM
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BU of 6ujm by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00013
分子名称: Glutaminase kidney isoform, mitochondrial, N-{5-[(3R)-3-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]amino}pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide
著者Huang, Q, Cerione, R.A.
登録日2019-10-03
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00013
To Be Published
3N75
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BU of 3n75 by Molmil
X-ray Crystal Structure of the Escherichia coli Inducible Lysine Decarboxylase LdcI
分子名称: GLYCEROL, GUANOSINE-5',3'-TETRAPHOSPHATE, HEXAETHYLENE GLYCOL, ...
著者Kanjee, U, Alexopoulos, E, Pai, E.F, Houry, W.A.
登録日2010-05-26
公開日2011-02-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase.
Embo J., 30, 2011
3Q16
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BU of 3q16 by Molmil
Linkage between the Bacterial Acid Stress and Stringent Responses: The Structure of the Inducible Lysine Decarboxylase
分子名称: Lysine decarboxylase, inducible
著者El Bakkouri, M, Pai, E.F, Houry, W.A.
登録日2010-12-16
公開日2011-02-16
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase.
Embo J., 30, 2011
6ULJ
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BU of 6ulj by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00012
分子名称: 2-phenyl-N-{6-[4-({6-[(phenylacetyl)amino]pyridazin-3-yl}oxy)piperidin-1-yl]pyridazin-3-yl}acetamide, Glutaminase kidney isoform, mitochondrial
著者Huang, Q, Cerione, R.A.
登録日2019-10-08
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00045
To Be Published
6UK6
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BU of 6uk6 by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00018
分子名称: 5-{4-[(5-amino-1,3,4-thiadiazol-2-yl)oxy]piperidin-1-yl}-1,3,4-thiadiazol-2-amine, Glutaminase kidney isoform, mitochondrial
著者Huang, Q, Cerione, R.A.
登録日2019-10-04
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00018
To Be Published
6UJG
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BU of 6ujg by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00012
分子名称: Glutaminase kidney isoform, mitochondrial, N-{5-[(3S)-3-{[5-(acetylamino)-1,3,4-thiadiazol-2-yl]amino}pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide
著者Huang, Q, Cerione, R.A.
登録日2019-10-03
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00012
To Be Published
6UMD
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BU of 6umd by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00012
分子名称: 2-(pyridin-3-yl)-N-(5-{4-[(5-{[(pyridin-3-yl)acetyl]amino}-1,3,4-thiadiazol-2-yl)amino]piperidin-1-yl}-1,3,4-thiadiazol-2-yl)acetamide, Glutaminase kidney isoform, mitochondrial
著者Huang, Q, Cerione, R.A.
登録日2019-10-09
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00012
To Be Published
6UME
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BU of 6ume by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00012
分子名称: 2-(pyridin-3-yl)-N-(5-{4-[(5-{[(pyridin-3-yl)acetyl]amino}-1,3,4-thiadiazol-2-yl)amino]piperidin-1-yl}-1,3,4-thiadiazol-2-yl)acetamide, Glutaminase kidney isoform, mitochondrial
著者Huang, Q, Cerione, R.A.
登録日2019-10-09
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00012
To Be Published
6UMC
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BU of 6umc by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00012
分子名称: 2-phenyl-N-{5-[(3R)-3-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide, Glutaminase kidney isoform, mitochondrial
著者Huang, Q, Cerione, R.A.
登録日2019-10-09
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00012
To Be Published
6UMF
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BU of 6umf by Molmil
Crystal structure of human GAC in complex with inhibitor UPGL00012
分子名称: Glutaminase kidney isoform, mitochondrial, N-(5-{[1-(5-amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy}-1,3,4-thiadiazol-2-yl)-2-phenylacetamide
著者Huang, Q, Cerione, R.A.
登録日2019-10-09
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Crystal structure of human GAC in complex with inhibitor UPGL00012
To Be Published
2QRZ
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BU of 2qrz by Molmil
Cdc42 bound to GMP-PCP: Induced Fit by Effector is Required
分子名称: Cell division control protein 42 homolog precursor, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Phillips, M.J, Calero, G, Chan, B, Cerione, R.A.
登録日2007-07-30
公開日2008-03-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Effector Proteins Exert an Important Influence on the Signaling-active State of the Small GTPase Cdc42.
J.Biol.Chem., 283, 2008
1A0K
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BU of 1a0k by Molmil
PROFILIN I FROM ARABIDOPSIS THALIANA
分子名称: PROFILIN
著者Shigeta Junior, R, Huddler, D, Lindberg, U, Schutt, C.E.
登録日1997-12-02
公開日1998-03-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of a major allergen from plants.
Structure, 5, 1997
2K0U
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BU of 2k0u by Molmil
High Resolution Solution NMR Structures of Oxaliplatin-DNA Adduct
分子名称: CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II), DNA (5'-D(*DCP*DCP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DTP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DAP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DGP*DG)-3')
著者Bhattacharyya, D, King, C.L, Chaney, S.G, Campbell, S.L.
登録日2008-02-15
公開日2009-02-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links.
Plos One, 6, 2011
2K0V
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BU of 2k0v by Molmil
High Resolution Solution NMR Structures of Undamaged DNA Dodecamer Duplex
分子名称: DNA (5'-D(*DCP*DCP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DTP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DAP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DGP*DG)-3')
著者Bhattacharyya, D, King, C.L, Chaney, S.G, Campbell, S.L.
登録日2008-02-15
公開日2009-02-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links.
Plos One, 6, 2011
2K0T
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BU of 2k0t by Molmil
High Resolution Solution NMR Structures of Oxaliplatin-DNA Adduct
分子名称: CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II), DNA (5'-D(*DCP*DCP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DTP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DAP*DGP*DAP*DCP*DCP*DAP*DGP*DAP*DGP*DG)-3')
著者Bhattacharyya, D, King, C.L, Chaney, S.G, Campbell, S.L.
登録日2008-02-14
公開日2009-02-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links.
Plos One, 6, 2011
3NUL
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BU of 3nul by Molmil
Profilin I from Arabidopsis thaliana
分子名称: GLYCEROL, PROFILIN I, SULFATE ION
著者Thorn, K, Christensen, H.E.M, Shigeta, R, Huddler, D, Chua, N.-H, Shalaby, L, Lindberg, U, Schutt, C.E.
登録日1996-11-27
公開日1997-12-03
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of a major allergen from plants.
Structure, 5, 1997
2MQ1
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BU of 2mq1 by Molmil
Phosphotyrosine binding domain
分子名称: E3 ubiquitin-protein ligase Hakai, ZINC ION
著者Mukherjee, M, Jing-Song, F, Sivaraman, J.
登録日2014-06-11
公開日2014-08-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric switch of Hakai-truncated monomers during substrate recognition: insights from solution studies and NMR structure.
J.Biol.Chem., 289, 2014

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