3X00
| Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with bis iminobiotin long tail (Bis-IMNtail) at 1.3 A resolution | 分子名称: | 6-({5-[(2E,3aS,4S,6aR)-2-iminohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)hexanoic acid, ETHANE-1,2-DIAMINE, Streptavidin | 著者 | Kawato, T, Mizohata, E, Shimizu, Y, Meshizuka, T, Yamamoto, T, Takasu, N, Matsuoka, M, Matsumura, H, Kodama, T, Kanai, M, Doi, H, Inoue, T, Sugiyama, A. | 登録日 | 2014-10-09 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure-based design and synthesis of a bivalent iminobiotin analog showing strong affinity toward a low immunogenic streptavidin mutant. Biosci.Biotechnol.Biochem., 79, 2015
|
|
3WII
| Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1. | 分子名称: | anti-human ROBO1 antibody B2212A Fab heavy chain, anti-human ROBO1 antibody B2212A Fab light chain | 著者 | Nakayama, T, Mizohata, E, Yamashita, T, Nagatoishi, S, Nakakido, M, Iwanari, H, Mochizuki, Y, Kado, Y, Yokota, Y, Sato, R, Tsumoto, K, Fujitani, H, Kodama, T, Hamakubo, T, Inoue, T. | 登録日 | 2013-09-12 | 公開日 | 2015-01-21 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses Protein Sci., 24, 2015
|
|
8XE4
| norbelladine 4'-O-methyltransferase complexed with Mg, SAH, and norbelladine | 分子名称: | GLYCEROL, MAGNESIUM ION, Norbelladine, ... | 著者 | Saw, Y.Y.H, Nakashima, Y, Morita, H. | 登録日 | 2023-12-11 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
|
|
8Z8O
| |
8XDT
| |
8ZFW
| |
7VI4
| Electron crystallographic structure of TIA-1 prion-like domain, A381T mutant | 分子名称: | TIA-1 prion-like domain | 著者 | Takaba, K, Maki-Yonekura, S, Sekiyama, N, Imamura, K, Kodama, T, Tochio, H, Yonekura, K. | 登録日 | 2021-09-24 | 公開日 | 2022-09-28 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.95 Å) | 主引用文献 | ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7VI5
| Electron crystallographic structure of TIA-1 prion-like domain, wild type sequence | 分子名称: | TIA-1 prion-like domain | 著者 | Takaba, K, Maki-Yonekura, S, Sekiyama, N, Imamura, K, Kodama, T, Tochio, H, Yonekura, K. | 登録日 | 2021-09-24 | 公開日 | 2022-09-28 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.761 Å) | 主引用文献 | ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
6A77
| Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the Fab fragment of murine monoclonal antibody B5209B | 分子名称: | Heavy chain of the anti-human Robo1 antibody B5209B Fab, Light chain of the anti-human Robo1 antibody B5209B Fab, Roundabout homolog 1 | 著者 | Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. | 登録日 | 2018-07-02 | 公開日 | 2019-01-30 | 最終更新日 | 2019-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
|
|
6A76
| Crystal structure of the Fab fragment of B5209B, a murine monoclonal antibody specific for the fifth immunoglobulin domain (Ig5) of human ROBO1 | 分子名称: | GLYCEROL, Heavy chain of the anti-human Robo1 antibody B5209B Fab, Light chain of the anti-human Robo1 antibody B5209B Fab, ... | 著者 | Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. | 登録日 | 2018-07-02 | 公開日 | 2019-01-30 | 最終更新日 | 2019-03-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
|
|
6A78
| Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the scFv fragment of murine monoclonal antibody B5209B | 分子名称: | Heavy chain and linker region of the anti-human Robo1 antibody B5209B scFv, Light chain region of the anti-human Robo1 antibody B5209B scFv, Roundabout homolog 1, ... | 著者 | Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. | 登録日 | 2018-07-02 | 公開日 | 2019-01-30 | 最終更新日 | 2019-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
|
|
6A79
| Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the mutant scFv fragment (P103A) of murine monoclonal antibody B5209B | 分子名称: | Heavy chain of the anti-human Robo1 antibody B5209B scFv, Light chain region of the anti-human Robo1 antibody B5209B scFv, Roundabout homolog 1, ... | 著者 | Mizohata, E, Nakayama, T, Kado, Y, Yokota, Y, Inoue, T. | 登録日 | 2018-07-02 | 公開日 | 2019-01-30 | 最終更新日 | 2019-03-20 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
|
|
7XVJ
| |
5B0D
| Polyketide cyclase OAC from Cannabis sativa, Y27W mutant | 分子名称: | Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B09
| Polyketide cyclase OAC from Cannabis sativa bound with Olivetolic acid | 分子名称: | 2,4-bis(oxidanyl)-6-pentyl-benzoic acid, Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B0G
| Polyketide cyclase OAC from Cannabis sativa, H78S mutant | 分子名称: | Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B0F
| Polyketide cyclase OAC from Cannabis sativa, Y72F mutant | 分子名称: | GLYCEROL, Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B0C
| Polyketide cyclase OAC from Cannabis sativa, Y27F mutant | 分子名称: | Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B0B
| Polyketide cyclase OAC from Cannabis sativa, I7F mutant | 分子名称: | ACETATE ION, Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.187 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B08
| Polyketide cyclase OAC from Cannabis sativa | 分子名称: | Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.325 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B0A
| Polyketide cyclase OAC from Cannabis sativa, H5Q mutant | 分子名称: | Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
5B0E
| Polyketide cyclase OAC from Cannabis sativa, V59M mutant | 分子名称: | GLYCEROL, Olivetolic acid cyclase | 著者 | Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H. | 登録日 | 2015-10-28 | 公開日 | 2016-01-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.603 Å) | 主引用文献 | Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa Febs J., 283, 2016
|
|
3AOX
| X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802 | 分子名称: | 1,2-ETHANEDIOL, 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, ALK tyrosine kinase receptor | 著者 | Nagel, S, Moertl, M, Jestel, A, Fukami, T.A. | 登録日 | 2010-10-08 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant Cancer Cell, 19, 2011
|
|
7Y3V
| Crystal structure of CdpNPT in complex with harmane | 分子名称: | 1-methyl-9H-pyrido[3,4-b]indole, Cyclic dipeptide N-prenyltransferase, PHOSPHATE ION | 著者 | Nakashima, Y, Morita, H. | 登録日 | 2022-06-13 | 公開日 | 2023-04-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Catalytic potential of a fungal indole prenyltransferase toward beta-carbolines, harmine and harman, and their prenylation effects on antibacterial activity. J.Biosci.Bioeng., 134, 2022
|
|
7FFH
| Diarylpentanoid-producing polyketide synthase (N199L mutant) | 分子名称: | Type III polyketide synthase | 著者 | Morita, H, Wong, C.P, Liu, Q, Takeshi, K, Lee, Y, Nakashima, Y. | 登録日 | 2021-07-23 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood. Nat Commun, 13, 2022
|
|