5WDQ
 
 | | H-Ras mutant L120A bound to GMP-PNP at 100K | | 分子名称: | ACETATE ION, CALCIUM ION, GTPase HRas, ... | | 著者 | Bandaru, P, Gee, C.L, Kuriyan, J. | | 登録日 | 2017-07-05 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
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5WDS
 | | Choanoflagellate Salpingoeca rosetta Ras with GDP bound | | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kondo, Y, Gee, C.L, Kuriyan, J. | | 登録日 | 2017-07-05 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
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5WGP
 | | Human Carbonic Anhydrase IX-mimic complexed with AceK | | 分子名称: | Acesulfame, Carbonic anhydrase 2, ZINC ION | | 著者 | Murray, A.B, Lomelino, C.L, Supuran, C.T, McKenna, R. | | 登録日 | 2017-07-14 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | "Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms.
J. Med. Chem., 61, 2018
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4V9I
 | | Crystal structure of thermus thermophilus 70S in complex with tRNAs and mRNA containing a pseudouridine in a stop codon | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S Ribosomal protein S10, ... | | 著者 | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | | 登録日 | 2013-04-04 | | 公開日 | 2014-07-09 | | 最終更新日 | 2014-12-10 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
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4V4M
 | | 1.45 Angstrom Structure of STNV coat protein | | 分子名称: | CALCIUM ION, Coat protein | | 著者 | Lane, S.W, Dennis, C.A, Lane, C.L, Trinh, C.H, Rizkallah, P.J, Stockley, P.G, Phillips, S.E.V. | | 登録日 | 2011-04-28 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Construction and crystal structure of recombinant STNV capsids.
J.Mol.Biol., 413, 2011
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5WLV
 | | Carbonic Anhydrase II in complex with aryloxy-2-hydroxypropylammine sulfonamide | | 分子名称: | 4-{(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}-N-[2-(4-sulfamoylphenyl)ethyl]benzamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Lomelino, C.L, Andring, J.T, McKenna, R. | | 登録日 | 2017-07-27 | | 公開日 | 2018-08-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Discovery of beta-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.
J. Med. Chem., 61, 2018
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5WDR
 | | Choanoflagellate Salpingoeca rosetta Ras with GMP-PNP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras protein, ... | | 著者 | Kondo, Y, Gee, C.L, Kuriyan, J. | | 登録日 | 2017-07-05 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Deconstruction of the Ras switching cycle through saturation mutagenesis.
Elife, 6, 2017
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4V5K
 | | Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | | 著者 | Ng, C.L, Lang, K, Meenan, N.A.G, Sharma, A, Kelley, A.C, Kleanthous, C, Ramakrishnan, V. | | 登録日 | 2010-05-29 | | 公開日 | 2014-07-09 | | 最終更新日 | 2019-07-31 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3.
Nat.Struct.Mol.Biol., 17, 2010
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2ROC
 | | Solution structure of Mcl-1 Complexed with Puma | | 分子名称: | Bcl-2-binding component 3, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | | 著者 | Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G. | | 登録日 | 2008-03-17 | | 公開日 | 2008-07-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.Mol.Biol., 380, 2008
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2ROD
 | | Solution Structure of MCL-1 Complexed with NoxaA | | 分子名称: | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Noxa | | 著者 | Day, C.L, Smits, C, Fan, F.C, Lee, E.F, Fairlie, W.D, Hinds, M.G. | | 登録日 | 2008-03-17 | | 公開日 | 2008-07-08 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.Mol.Biol., 380, 2008
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1NKI
 | | CRYSTAL STRUCTURE OF THE FOSFOMYCIN RESISTANCE PROTEIN A (FOSA) CONTAINING BOUND PHOSPHONOFORMATE | | 分子名称: | MANGANESE (II) ION, PHOSPHONOFORMIC ACID, POTASSIUM ION, ... | | 著者 | Rife, C.L, Pharris, R.E, Newcomer, M.E, Armstrong, R.N. | | 登録日 | 2003-01-03 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA.
Biochemistry, 43, 2004
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1NNR
 | | Crystal structure of a probable fosfomycin resistance protein (PA1129) from Pseudomonas aeruginosa with sulfate present in the active site | | 分子名称: | MANGANESE (II) ION, SULFATE ION, probable fosfomycin resistance protein | | 著者 | Rife, C.L, Pharris, R.E, Newcomer, M.E, Armstrong, R.N. | | 登録日 | 2003-01-14 | | 公開日 | 2004-01-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Phosphonoformate: a minimal transition state analogue inhibitor of the fosfomycin resistance protein, FosA.
Biochemistry, 43, 2004
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5YNX
 | | Structure of house dust mite allergen Der f 21 in PEG400 | | 分子名称: | Allergen Der f 21, BETA-MERCAPTOETHANOL, GLYCEROL, ... | | 著者 | Ng, C.L, Chew, F.T, Pang, S.L, Ho, K.L, Teh, A.H, Waterman, J, Rambo, R, Mathavan, I, Beis, K, Say, Y.H. | | 登録日 | 2017-10-25 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Crystal structure and epitope analysis of house dust mite allergen Der f 21.
Sci Rep, 9, 2019
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5YNY
 | | Structure of house dust mite allergen Der F 21 in PEG2KMME | | 分子名称: | Allergen Der f 21 | | 著者 | Ng, C.L, Chew, F.T, Pang, S.L, Ho, K.L, Teh, A.H, Waterman, J, Rambo, R, Mathavan, I. | | 登録日 | 2017-10-25 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure and epitope analysis of house dust mite allergen Der f 21.
Sci Rep, 9, 2019
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6CIP
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6CNK
 | | Structure of the 3alpha2beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Hibbs, R.E. | | 登録日 | 2018-03-08 | | 公開日 | 2018-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor.
Nature, 557, 2018
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6CBQ
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6CIN
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6CCD
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6CNJ
 | | Structure of the 2alpha3beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Walsh Jr, R.M, Roh, S.H, Gharpure, A, Morales-Perez, C.L, Teng, J, Hibbs, R.E. | | 登録日 | 2018-03-08 | | 公開日 | 2018-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor.
Nature, 557, 2018
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6CC0
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6CIQ
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3LT8
 | | A non-biological ATP binding protein with a single point mutation (D65V), that contributes to optimized folding and ligand binding, crystallized in the presence of 100 mM ATP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-D65V, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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3LT9
 | | A non-biological ATP binding protein with a single point mutation (D65V), that contributes to optimized folding and ligand binding | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-D65V, CHLORIDE ION, ... | | 著者 | Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C. | | 登録日 | 2010-02-15 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
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6CGA
 | | Structure of the PR-DUB complex | | 分子名称: | Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso | | 著者 | Foglizzo, M, Middleton, A.J, Day, C.L, Mace, P.D. | | 登録日 | 2018-02-19 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.
Nat Commun, 9, 2018
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