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5N2G
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BU of 5n2g by Molmil
Structure of the E9 DNA polymerase from vaccinia virus in complex with manganese
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Tarbouriech, N, Burmeister, W.P, Iseni, F.
登録日2017-02-07
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
Nat Commun, 8, 2017
5EPI
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CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT
分子名称: CRNA 5' END, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Guilligay, D, Cusack, S.
登録日2015-11-11
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.
Mol.Cell, 61, 2016
5FML
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BU of 5fml by Molmil
Crystal structure of the endonuclease from the PA subunit of influenza B virus bound to the PB2 subunit NLS peptide
分子名称: GLYCEROL, MAGNESIUM ION, PA SUBUNIT OF INFLUENZA B POLYMERASE, ...
著者Guilligay, D, Gaudon, S, Cusack, S.
登録日2015-11-06
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Mol.Cell, 61, 2016
5FMZ
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BU of 5fmz by Molmil
Crystal structure of Influenza B polymerase with bound 5' vRNA
分子名称: 5'-R(*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP)-3', POLYMERASE ACIDIC PROTEIN, POLYMERASE BASIC PROTEIN 2, ...
著者Guilligay, D, Cusack, S.
登録日2015-11-10
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains.
Mol.Cell, 61, 2016
1YRP
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BU of 1yrp by Molmil
Catalytic domain of human ZIP kinase phosphorylated at Thr265
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Death-associated protein kinase 3
著者Kursula, P, Vahokoski, J, Wilmanns, M.
登録日2005-02-04
公開日2006-06-20
最終更新日2016-05-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites
Structure, 2016
2A2A
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BU of 2a2a by Molmil
High-resolution crystallographic analysis of the autoinhibited conformation of a human death-associated protein kinase
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Death-associated protein kinase 2, ...
著者Kursula, P, Wilmanns, M.
登録日2005-06-22
公開日2006-10-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites
Structure, 2016
4UAF
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BU of 4uaf by Molmil
Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain
分子名称: Importin subunit alpha-1, PHOSPHATE ION, Polymerase basic protein 2
著者Pumroy, R.A, Cingolani, G.
登録日2014-08-08
公開日2015-02-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Molecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7.
Structure, 23, 2015
5KE1
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BU of 5ke1 by Molmil
Structure of a C-terminal fragment of the IcsA/VirG passenger-domain
分子名称: NICKEL (II) ION, Outer membrane protein IcsA autotransporter
著者Leupold, S, Scrima, A.
登録日2016-06-09
公開日2017-03-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the architecture of the Shigella flexneri virulence factor IcsA/VirG and motifs involved in polar distribution and secretion.
J. Struct. Biol., 198, 2017
6ZYC
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Solution structure of the C-terminal domain of the vaccinia virus DNA polymerase processivity factor component A20.
分子名称: DNA polymerase processivity factor component A20
著者Bersch, B, Iseni, F, Burmeister, W, Tarbouriech, N.
登録日2020-07-31
公開日2021-05-19
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution Structure of the C-terminal Domain of A20, the Missing Brick for the Characterization of the Interface between Vaccinia Virus DNA Polymerase and its Processivity Factor.
J.Mol.Biol., 433, 2021
6ZXP
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BU of 6zxp by Molmil
Solution structure of the C-terminal domain of the vaccinia virus DNA polymerase processivity factor component A20 fused to a short peptide from the viral DNA polymerase E9.
分子名称: DNA polymerase processivity factor component A20,DNA polymerase processivity factor component E9
著者Bersch, B, Tarbouriech, N, Burmeister, W, Iseni, F.
登録日2020-07-30
公開日2021-05-19
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Solution Structure of the C-terminal Domain of A20, the Missing Brick for the Characterization of the Interface between Vaccinia Virus DNA Polymerase and its Processivity Factor.
J.Mol.Biol., 433, 2021
5MQH
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BU of 5mqh by Molmil
Structure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilis in a crystal form without domain swapping
分子名称: Serine phosphatase
著者Levdikov, V.M, Wilkinson, A.J, Blagova, E.V.
登録日2016-12-20
公開日2017-05-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.
Elife, 6, 2017
1FHG
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BU of 1fhg by Molmil
HIGH RESOLUTION REFINEMENT OF TELOKIN
分子名称: TELOKIN
著者Tomchick, D.R, Minor, W, Kiyatkin, A, Lewinski, K, Somlyo, A.V, Somlyo, A.P.
登録日2000-08-01
公開日2000-08-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 A resolution.
J.Mol.Biol., 227, 1992
2SFP
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BU of 2sfp by Molmil
ALANINE RACEMASE WITH BOUND PROPIONATE INHIBITOR
分子名称: PROPANOIC ACID, PROTEIN (ALANINE RACEMASE), PYRIDOXAL-5'-PHOSPHATE
著者Morollo, A.A, Petsko, G.A, Ringe, D.
登録日1999-02-16
公開日1999-02-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase.
Biochemistry, 38, 1999
1MRA
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BU of 1mra by Molmil
MANDELATE RACEMASE MUTANT D270N CO-CRYSTALLIZED WITH (S)-ATROLACTATE
分子名称: ATROLACTIC ACID (2-PHENYL-LACTIC ACID), MAGNESIUM ION, MANDELATE RACEMASE
著者Clifton, J.G, Petsko, G.A.
登録日1996-03-12
公開日1996-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the D270N mutant.
Biochemistry, 35, 1996
3F6X
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BU of 3f6x by Molmil
c-Src kinase domain in complex with small molecule inhibitor
分子名称: Proto-oncogene tyrosine-protein kinase Src, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile
著者Seeliger, M.A, Statsuk, A.V, Maly, D.J, Patrick, P.Z, Kuriyan, J, Shokat, K.M.
登録日2008-11-06
公開日2008-12-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Tuning a three-component reaction for trapping kinase substrate complexes.
J.Am.Chem.Soc., 130, 2008
4PHV
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BU of 4phv by Molmil
X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY
分子名称: HIV-1 PROTEASE, N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE
著者Bone, R.
登録日1991-10-04
公開日1993-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry
J.Am.Chem.Soc., 113, 1991
1MDL
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BU of 1mdl by Molmil
MANDELATE RACEMASE MUTANT K166R CO-CRYSTALLIZED WITH (R)-MANDELATE
分子名称: (R)-MANDELIC ACID, (S)-MANDELIC ACID, MAGNESIUM ION, ...
著者Clifton, J.G, Petsko, G.A.
登録日1996-03-29
公開日1996-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the K166R mutant.
Biochemistry, 34, 1995
2F4J
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BU of 2f4j by Molmil
Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680
分子名称: CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, Proto-oncogene tyrosine-protein kinase ABL1
著者Young, M.A, Shah, N.P, Chao, L.H, Zarrinkar, P, Sawyers, P, Kuriyan, J.
登録日2005-11-23
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.
Cancer Res., 66, 2006
1DTN
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BU of 1dtn by Molmil
MANDELATE RACEMASE MUTANT D270N CO-CRYSTALLIZED WITH (S)-ATROLACTATE
分子名称: ATROLACTIC ACID (2-PHENYL-LACTIC ACID), MAGNESIUM ION, MANDELATE RACEMASE
著者Clifton, J.G, Petsko, G.A.
登録日1996-03-28
公開日1996-10-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of the reaction catalyzed by mandelate racemase: importance of electrophilic catalysis by glutamic acid 317.
Biochemistry, 34, 1995
1TUL
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BU of 1tul by Molmil
STRUCTURE OF TLP20
分子名称: TLP20
著者Rayment, I, Holden, H.M.
登録日1996-08-17
公開日1997-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular structure of a proteolytic fragment of TLP20.
Acta Crystallogr.,Sect.D, 52, 1996
1TLK
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X-RAY STRUCTURE DETERMINATION OF TELOKIN, THE C-TERMINAL DOMAIN OF MYOSIN LIGHT CHAIN KINASE, AT 2.8 ANGSTROMS RESOLUTION
分子名称: TELOKIN
著者Holden, H.M, Rayment, I.
登録日1992-07-20
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 A resolution.
J.Mol.Biol., 227, 1992
1CKP
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BU of 1ckp by Molmil
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B
分子名称: 1,2-ETHANEDIOL, PROTEIN (CYCLIN-DEPENDENT PROTEIN KINASE 2), PURVALANOL B
著者Gray, N.S, Thunnissen, A.M.W.H, Schultz, P.G, Kim, S.H.
登録日1998-07-14
公開日1999-01-13
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Science, 281, 1998
1PSA
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BU of 1psa by Molmil
STRUCTURE OF A PEPSIN(SLASH)RENIN INHIBITOR COMPLEX REVEALS A NOVEL CRYSTAL PACKING INDUCED BY MINOR CHEMICAL ALTERATIONS IN THE INHIBITOR
分子名称: N-(ethoxycarbonyl)-L-leucyl-N-[(1R,2S,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-leucinamide, PEPSIN A
著者Chen, L, Abad-Zapatero, C.
登録日1991-10-22
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of a pepsin/renin inhibitor complex reveals a novel crystal packing induced by minor chemical alterations in the inhibitor.
Acta Crystallogr.,Sect.B, 48, 1992
1SFT
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BU of 1sft by Molmil
ALANINE RACEMASE
分子名称: ACETATE ION, ALANINE RACEMASE, PYRIDOXAL-5'-PHOSPHATE
著者Shaw, J.P, Petsko, G.A, Ringe, D.
登録日1996-09-20
公開日1997-02-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution.
Biochemistry, 36, 1997
1BD0
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ALANINE RACEMASE COMPLEXED WITH ALANINE PHOSPHONATE
分子名称: ALANINE RACEMASE, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID
著者Stamper, G.F, Morollo, A.A, Ringe, D.
登録日1998-05-12
公開日1998-10-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine.
Biochemistry, 37, 1998

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