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5VMW
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BU of 5vmw by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2017-04-28
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMU
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BU of 5vmu by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2017-04-28
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.346 Å)
主引用文献CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
5VMZ
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BU of 5vmz by Molmil
Kaiso (ZBTB33) E535Q mutant zinc finger DNA binding domain in complex with a double CpG-methylated DNA resembling the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*(5CM)P*GP*(5CM)P*GP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*(5CM)P*GP*(5CM)P*GP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2017-04-28
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.319 Å)
主引用文献CH···O Hydrogen Bonds Mediate Highly Specific Recognition of Methylated CpG Sites by the Zinc Finger Protein Kaiso.
Biochemistry, 57, 2018
1CUR
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BU of 1cur by Molmil
REDUCED RUSTICYANIN, NMR
分子名称: COPPER (II) ION, CU(I) RUSTICYANIN
著者Botuyan, M.V, Dyson, H.J.
登録日1996-04-19
公開日1996-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential.
J.Mol.Biol., 263, 1996
2M9E
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BU of 2m9e by Molmil
NMR solution structure of Pin1 WW domain mutant 5-1
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
登録日2013-06-07
公開日2013-06-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2M9I
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BU of 2m9i by Molmil
NMR solution structure of Pin1 WW domain variant 6-1
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W.
登録日2013-06-10
公開日2013-06-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
J.Am.Chem.Soc., 135, 2013
2PRT
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BU of 2prt by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-05-04
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
4H6J
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BU of 4h6j by Molmil
Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain protein-protein interaction.
分子名称: ARYL HYDROCARBON NUCLEAR TRANSLOCATOR, HYPOXIA INDUCIBLE FACTOR 1-ALPHA
著者Cardoso, R, Love, R.A, Nilsson, C, Bergqvist, S, Nowlin, D, Yan, J, Liu, K, Zhu, J, Chen, P, Deng, Y.-L, Dyson, H.J, Greig, M.J, Brooun, A.
登録日2012-09-19
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction.
Protein Sci., 21, 2012
1IE5
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BU of 1ie5 by Molmil
NMR STRUCTURE OF THE THIRD IMMUNOGLOBULIN DOMAIN FROM THE NEURAL CELL ADHESION MOLECULE.
分子名称: NEURAL CELL ADHESION MOLECULE
著者Atkins, A.R, Chung, J, Deechongkit, S, Little, E.B, Edelman, G.M, Wright, P.E, Cunningham, B.A, Dyson, H.J.
登録日2001-04-06
公開日2001-08-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?
J.Mol.Biol., 311, 2001
1LO1
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BU of 1lo1 by Molmil
ESTROGEN RELATED RECEPTOR 2 DNA BINDING DOMAIN IN COMPLEX WITH DNA
分子名称: 5'-D(*CP*GP*TP*GP*AP*CP*CP*TP*TP*GP*AP*GP*C)-3', 5'-D(*GP*CP*TP*CP*AP*AP*GP*GP*TP*CP*AP*CP*G)-3', Steroid hormone receptor ERR2, ...
著者Gearhart, M.D, Holmbeck, S.M.A, Evans, R.M, Dyson, H.J, Wright, P.E.
登録日2002-05-05
公開日2003-04-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Monomeric Complex of Human Orphan Estrogen Related Receptor-2 with DNA: A Pseudo-dimer Interface Mediates Extended Half-site Recognition
J.Mol.Biol., 327, 2003
1L8C
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BU of 1l8c by Molmil
STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE
分子名称: CREB-binding protein, Hypoxia-inducible factor 1 alpha, ZINC ION
著者Dames, S.A, Martinez-Yamout, M, De Guzman, R.N, Dyson, H.J, Wright, P.E.
登録日2002-03-19
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.
Proc.Natl.Acad.Sci.USA, 99, 2002
1NO8
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BU of 1no8 by Molmil
SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN
分子名称: ALY
著者Perez-Alvarado, G.C, Martinez-Yamout, M, Allen, M.M, Grosschedl, R, Dyson, H.J, Wright, P.E.
登録日2003-01-15
公開日2003-08-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Nuclear Factor ALY: Insights into Post-Transcriptional Regulatory and mRNA Nuclear Export Processes
Biochemistry, 42, 2003
1KDX
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BU of 1kdx by Molmil
KIX DOMAIN OF MOUSE CBP (CREB BINDING PROTEIN) IN COMPLEX WITH PHOSPHORYLATED KINASE INDUCIBLE DOMAIN (PKID) OF RAT CREB (CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN), NMR 17 STRUCTURES
分子名称: CBP, CREB
著者Radhakrishnan, I, Perez-Alvarado, G.C, Dyson, H.J, Wright, P.E.
登録日1997-09-16
公開日1998-11-25
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions.
Cell(Cambridge,Mass.), 91, 1997
1R8U
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BU of 1r8u by Molmil
NMR structure of CBP TAZ1/CITED2 complex
分子名称: CREB-binding protein, Cbp/p300-interacting transactivator 2, ZINC ION
著者De Guzman, R.N, Martinez-Yamout, M, Dyson, H.J, Wright, P.E.
登録日2003-10-28
公開日2004-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
J.Biol.Chem., 279, 2004
1KBH
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BU of 1kbh by Molmil
Mutual Synergistic Folding in the Interaction Between Nuclear Receptor Coactivators CBP and ACTR
分子名称: CREB-BINDING PROTEIN, nuclear receptor coactivator
著者Demarest, S.J, Martinez-Yamout, M, Chung, J, Chen, H, Xu, W, Dyson, H.J, Evans, R.M, Wright, P.E.
登録日2001-11-06
公開日2002-02-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.
Nature, 415, 2002
1RGO
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BU of 1rgo by Molmil
Structural Basis for Recognition of the mRNA Class II AU-Rich Element by the Tandem Zinc Finger Domain of TIS11d
分子名称: Butyrate response factor 2, RNA (5'-R(*UP*UP*AP*UP*UP*UP*AP*UP*U)-3'), ZINC ION
著者Hudson, B.P, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
登録日2003-11-12
公開日2004-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d.
NAT.STRUCT.MOL.BIOL., 11, 2004
1RXR
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BU of 1rxr by Molmil
HIGH RESOLUTION SOLUTION STRUCTURE OF THE RETINOID X RECEPTOR DNA BINDING DOMAIN, NMR, 20 STRUCTURE
分子名称: RETINOIC ACID RECEPTOR-ALPHA, ZINC ION
著者Holmbeck, S.M.A, Foster, M.P, Casimiro, D.R, Sem, D.S, Dyson, H.J, Wright, P.E.
登録日1998-06-12
公開日1998-11-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献High-resolution solution structure of the retinoid X receptor DNA-binding domain.
J.Mol.Biol., 281, 1998
1F62
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BU of 1f62 by Molmil
WSTF-PHD
分子名称: TRANSCRIPTION FACTOR WSTF, ZINC ION
著者Pascual, J, Martinez-Yamout, M, Dyson, H.J, Wright, P.E.
登録日2000-06-19
公開日2000-12-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor.
J.Mol.Biol., 304, 2000
1G7O
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BU of 1g7o by Molmil
NMR SOLUTION STRUCTURE OF REDUCED E. COLI GLUTAREDOXIN 2
分子名称: GLUTAREDOXIN 2
著者Xia, B, Vlamis-Gardikas, A, Holmgren, A, Wright, P.E, Dyson, H.J.
登録日2000-11-10
公開日2001-07-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Escherichia coli glutaredoxin-2 shows similarity to mammalian glutathione-S-transferases.
J.Mol.Biol., 310, 2001
1F81
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BU of 1f81 by Molmil
SOLUTION STRUCTURE OF THE TAZ2 DOMAIN OF THE TRANSCRIPTIONAL ADAPTOR PROTEIN CBP
分子名称: CREB-BINDING PROTEIN, ZINC ION
著者De Guzman, R.N, Liu, H.L, Martinez-Yamout, M, Dyson, H.J, Wright, P.E.
登録日2000-06-28
公開日2000-10-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP.
J.Mol.Biol., 303, 2000
1I17
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BU of 1i17 by Molmil
NMR STRUCTURE OF MOUSE DOPPEL 51-157
分子名称: PRION-LIKE PROTEIN
著者Mo, H, Moore, R.C, Cohen, F.E, Westaway, D, Prusiner, S.B, Wright, P.E, Dyson, H.J.
登録日2001-01-31
公開日2001-03-07
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Two different neurodegenerative diseases caused by proteins with similar structures.
Proc.Natl.Acad.Sci.USA, 98, 2001
1F68
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BU of 1f68 by Molmil
NMR SOLUTION STRUCTURE OF THE BROMODOMAIN FROM HUMAN GCN5
分子名称: HISTONE ACETYLTRANSFERASE
著者Wright, P.E, Hudson, B.P, Dyson, H.J.
登録日2000-06-20
公開日2000-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.
J.Mol.Biol., 304, 2000
1COU
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BU of 1cou by Molmil
ANTICOAGULANT PROTEIN FROM THE NEMATODE ANCYLOSTOMA CANINUM
分子名称: PROTEIN (NEMATODE ANTICOAGULANT PROTEIN C2)
著者Duggan, B.M, Dyson, H.J, Wright, P.E.
登録日1999-05-28
公開日1999-10-20
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Inherent flexibility in a potent inhibitor of blood coagulation, recombinant nematode anticoagulant protein c2.
Eur.J.Biochem., 265, 1999
4F6N
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BU of 4f6n by Molmil
Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
分子名称: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F6M
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BU of 4f6m by Molmil
Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012

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