2L89
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6VXP
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4EQ8
| Crystal structure of PA1844 from Pseudomonas aeruginosa PAO1 | 分子名称: | GLYCEROL, Putative uncharacterized protein | 著者 | Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L. | 登録日 | 2012-04-18 | 公開日 | 2012-09-12 | 最終更新日 | 2013-07-24 | 実験手法 | X-RAY DIFFRACTION (1.392 Å) | 主引用文献 | Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function. Biochem.J., 448, 2012
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6WDN
| Cryo-EM structure of mitochondrial calcium uniporter holocomplex in low Ca2+ | 分子名称: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | 著者 | Feng, L, Zhang, J, Fan, M. | 登録日 | 2020-04-01 | 公開日 | 2020-05-27 | 最終更新日 | 2020-06-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex. Nature, 582, 2020
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7CL0
| Crystal structure of human SIRT6 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ... | 著者 | Song, K, Zhang, J. | 登録日 | 2020-07-20 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Reply to: Binding site for MDL-801 on SIRT6. Nat.Chem.Biol., 17, 2021
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7CL1
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6WDO
| Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+ | 分子名称: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | 著者 | Feng, L, Zhang, J, Fan, M. | 登録日 | 2020-04-01 | 公開日 | 2020-05-27 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex. Nature, 582, 2020
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3GGQ
| Dimerization of Hepatitis E Virus Capsid Protein E2s Domain is Essential for Virus-Host Interaction | 分子名称: | BROMIDE ION, Capsid protein | 著者 | Li, S.W, Tang, X.H, Seetharaman, J, Yang, C.Y, Gu, Y, Zhang, J, Du, H.L, Shih, J.W.K, Hew, C.L, Sivaraman, J, Xia, N.S. | 登録日 | 2009-03-02 | 公開日 | 2009-08-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction Plos Pathog., 5, 2009
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4EQA
| Crystal structure of PA1844 in complex with PA1845 from Pseudomonas aeruginosa PAO1 | 分子名称: | Putative uncharacterized protein | 著者 | Shang, G, Li, N, Zhang, J, Lu, D, Yu, Q, Zhao, Y, Liu, X, Xu, S, Gu, L. | 登録日 | 2012-04-18 | 公開日 | 2012-09-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function. Biochem.J., 448, 2012
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7VVP
| Crystal structure of SARS-Cov-2 main protease in complex with PF07304814 | 分子名称: | 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate | 著者 | Zhou, X.L, Zhong, F.L, Lin, C, Zeng, P, Zhang, J, Li, J. | 登録日 | 2021-11-07 | 公開日 | 2022-08-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814 J.Mol.Biol., 434, 2022
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8TV9
| Inner Mat-T4P complex | 分子名称: | Fimbrial protein, Maturation protein | 著者 | Meng, R, Xing, Z, Thongchol, J, Zhang, J. | 登録日 | 2023-08-17 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (8.15 Å) | 主引用文献 | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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8TVA
| Outer Mat-T4P complex | 分子名称: | Fimbrial protein, Maturation protein | 著者 | Meng, R, Xing, Z, Thongchol, J, Zhang, J. | 登録日 | 2023-08-17 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (8.55 Å) | 主引用文献 | Structural basis of Acinetobacter type IV pili targeting by an RNA virus. Nat Commun, 15, 2024
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6JZO
| Structure of the mouse TRPC4 ion channel | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | 著者 | Duan, J, Li, Z, Li, J, Zhang, J. | 登録日 | 2019-05-03 | 公開日 | 2020-10-21 | 最終更新日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Structure of the mouse TRPC4 ion channel To Be Published
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8I29
| Crystal structure of butanol dehydrogenase A (YqdH) in complex with NADH from Fusobacterium nucleatum | 分子名称: | CHLORIDE ION, COBALT (II) ION, NADH-dependent butanol dehydrogenase A, ... | 著者 | Bai, X, Lan, J, Bu, T.T, Wang, L.L, He, S.R, Zhang, J, Xu, Y.B. | 登録日 | 2023-01-14 | 公開日 | 2023-02-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Crystal structure of butanol dehydrogenase A (YqdH) in complex with NADH from Fusobacterium nucleatum To Be Published
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8IU2
| Cryo-EM structure of Long-wave-sensitive opsin 1 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Peng, Q, Cheng, X.Y, Li, J, Lu, Q.Y, Li, Y.Y, Zhang, J. | 登録日 | 2023-03-23 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cryo-EM structure of Long-wave-sensitive opsin 1 To Be Published
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8J3B
| Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF00835231 | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | 著者 | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | 登録日 | 2023-04-16 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
S46F mutant in complex with PF00835231 To Be Published
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8J38
| Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with PF00835231 | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | 著者 | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | 登録日 | 2023-04-16 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
P132H mutant in complex with PF00835231 To Be Published
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8J3A
| Crystal structure of SARS-Cov-2 main protease Y54C mutant in complex with PF00835231 | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | 著者 | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | 登録日 | 2023-04-16 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
Y54C mutant in complex with PF00835231 To Be Published
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8J34
| Crystal structure of MERS main protease in complex with PF00835231 | 分子名称: | N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, ORF1a | 著者 | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | 登録日 | 2023-04-16 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of MERS main protease in complex with PF00835231 To Be Published
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8J35
| Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with PF00835231 | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | 著者 | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | 登録日 | 2023-04-16 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
G15S mutant in complex with PF00835231 To Be Published
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8J32
| Crystal structure of SARS-Cov-2 main protease in complex with PF00835231 | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | 著者 | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | 登録日 | 2023-04-16 | 公開日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease in complex with PF00835231 To Be Published
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1Z28
| Crystal Structures of SULT1A2 and SULT1A1*3: Implications in the bioactivation of N-hydroxy-2-acetylamino fluorine (OH-AAF) | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Phenol-sulfating phenol sulfotransferase 1 | 著者 | Lu, J, Li, H, Liu, M.C, Zhang, J, Li, M, An, X, Chang, W. | 登録日 | 2005-03-07 | 公開日 | 2006-05-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of SULT1A2 and SULT1A1 *3: insights into the substrate inhibition and the role of Tyr149 in SULT1A2. Biochem.Biophys.Res.Commun., 396, 2010
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8J36
| Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with PF00835231 | 分子名称: | 3C-like proteinase nsp5, N-[(2S)-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide | 著者 | Zhou, X.L, Lin, C, Zou, X.F, Zhang, J, Li, J. | 登録日 | 2023-04-16 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal structure of SARS-Cov-2 main protease
M49I mutant in complex with PF00835231 To Be Published
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8TWC
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4DDL
| PDE10a Crystal Structure Complexed with Novel Inhibitor | 分子名称: | 2-{1-[5-(6,7-dimethoxycinnolin-4-yl)-3-methylpyridin-2-yl]piperidin-4-yl}propan-2-ol, SULFATE ION, ZINC ION, ... | 著者 | Chmait, S, Jordan, S, Zhang, J. | 登録日 | 2012-01-18 | 公開日 | 2012-03-21 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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