7KKH
 
 | | P1A4 Fab in complex with ARS1620 | | 分子名称: | (S)-1-{4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl] piperazin-1-yl}propan-1-one, P1A4 Fab Heavy Chain, P1A4 Fab Light Chain, ... | | 著者 | Basu, K, Rohweder, P.J, Zhang, Z, Bohn, M.-F, Shokat, K, Craik, C.S. | | 登録日 | 2020-10-27 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy.
Cancer Cell, 40, 2022
|
|
8EOJ
 | | Microsomal triglyceride transfer protein | | 分子名称: | Microsomal triglyceride transfer protein large subunit, Protein disulfide-isomerase | | 著者 | Zhang, Z. | | 登録日 | 2022-10-03 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
|
|
8ENE
 | |
8EOR
 | | Liver carboxylesterase 1 | | 分子名称: | ETHYL ACETATE, Liver carboxylesterase 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Zhang, Z, Yu, E. | | 登録日 | 2022-10-04 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
|
|
3PX7
 | |
1AQC
 | |
1TPU
 | | S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE | | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D. | | 登録日 | 1994-11-07 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry, 35, 1996
|
|
1TPV
 | | S96P CHANGE IS A SECOND-SITE SUPPRESSOR FOR H95N SLUGGISH MUTANT TRIOSEPHOSPHATE ISOMERASE | | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D. | | 登録日 | 1994-11-07 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry, 35, 1996
|
|
1X11
 | | X11 PTB DOMAIN | | 分子名称: | 13-MER PEPTIDE, X11 | | 著者 | Lee, C.-H, Zhang, Z, Kuriyan, J. | | 登録日 | 1997-07-28 | | 公開日 | 1998-01-14 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
|
|
7UZM
 | |
5H6V
 | |
5H99
 | |
5H9I
 | | Crystal structure of Geobacter metallireducens SMUG1 with xanthine | | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, Geobacter metallireducens SMUG1, ... | | 著者 | Xie, W, Cao, W, Zhang, Z, Shen, J. | | 登録日 | 2015-12-28 | | 公開日 | 2016-04-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1
Acs Chem.Biol., 11, 2016
|
|
5H93
 | |
5H98
 | |
3KAE
 | | Cdc27 N-terminus | | 分子名称: | CHLORIDE ION, GLYCEROL, Possible protein of nuclear scaffold, ... | | 著者 | Barford, D, Zhang, Z, Roe, S.M. | | 登録日 | 2009-10-19 | | 公開日 | 2010-03-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | | 主引用文献 | Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture
J.Mol.Biol., 397, 2010
|
|
8X3E
 | | CYP725A4-Taxa-4,11-diene complex | | 分子名称: | (1~{R},3~{R},8~{R})-4,8,12,15,15-pentamethyltricyclo[9.3.1.0^{3,8}]pentadeca-4,11-diene, PROTOPORPHYRIN IX CONTAINING FE, Taxadiene 5-alpha hydroxylase | | 著者 | Chang, Z, Wang, Q. | | 登録日 | 2023-11-13 | | 公開日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Unraveling the Catalytic Mechanism of Taxadiene-5alpha-hydroxylase from Crystallography and Computational Analyses.
Acs Catalysis, 14, 2024
|
|
8X1W
 | | CYP725A4 apo structure | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Taxadiene 5-alpha hydroxylase | | 著者 | Chang, Z, Wang, Q. | | 登録日 | 2023-11-09 | | 公開日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Unraveling the Catalytic Mechanism of Taxadiene-5alpha-hydroxylase from Crystallography and Computational Analyses.
Acs Catalysis, 14, 2024
|
|
7DEU
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | | 著者 | Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y. | | 登録日 | 2020-11-05 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
|
|
8JHB
 | | FZD6 Gs complex | | 分子名称: | Frizzled-6, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, F, Zhang, Z. | | 登録日 | 2023-05-23 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
|
|
8JHI
 | | FZD3-Gs complex | | 分子名称: | Frizzled-3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, F, Zhang, Z. | | 登録日 | 2023-05-23 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
|
|
8JH7
 | | FZD6 in inactive state | | 分子名称: | Frizzled-6,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | | 著者 | Xu, F, Zhang, Z. | | 登録日 | 2023-05-22 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
|
|
8JHC
 | | FZD3 in inactive state | | 分子名称: | Frizzled-3,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ... | | 著者 | Xu, F, Zhang, Z. | | 登録日 | 2023-05-23 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways.
Cell Discov, 10, 2024
|
|
7XR4
 | |
7XR6
 | | Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with WAY-213613 | | 分子名称: | (2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acid, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Zhao, Y, Zhang, Z. | | 登録日 | 2022-05-09 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of ligand binding modes of human EAAT2.
Nat Commun, 13, 2022
|
|
