8BNZ
| BAM-EspP complex structure with BamA-G431C/EspP-N1293C mutations in nanodisc | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | 著者 | Shen, C, Chang, S, Luo, Q, Zhang, Z, Xie, T, Luo, B, Lu, G, Zhu, X, Wei, X, Dong, C, Zhou, R, Zhang, X, Tang, X, Dong, H. | 登録日 | 2022-11-14 | 公開日 | 2023-04-26 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of BAM-mediated outer membrane beta-barrel protein assembly. Nature, 617, 2023
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1G55
| Structure of human DNMT2, an enigmatic DNA methyltransferase homologue | 分子名称: | BETA-MERCAPTOETHANOL, DNA CYTOSINE METHYLTRANSFERASE DNMT2, GLYCEROL, ... | 著者 | Dong, A, Yoder, J.A, Zhang, X, Zhou, L, Bestor, T.H, Cheng, X. | 登録日 | 2000-10-30 | 公開日 | 2001-01-17 | 最終更新日 | 2018-06-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA. Nucleic Acids Res., 29, 2001
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1RKU
| Crystal Structure of ThrH gene product of Pseudomonas Aeruginosa | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, homoserine kinase | 著者 | Singh, S.K, Yang, K, Subramanian, K, Karthikeyan, S, Huynh, T, Zhang, X, Phillips, M.A, Zhang, H. | 登録日 | 2003-11-23 | 公開日 | 2004-03-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity. J.Biol.Chem., 279, 2004
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1I42
| NMR STRUCTURE OF THE UBX DOMAIN FROM P47 | 分子名称: | P47 | 著者 | Yuan, X, Shaw, A, Zhang, X, Kondo, H, Lally, J, Freemont, P.S, Matthews, S. | 登録日 | 2001-02-19 | 公開日 | 2001-08-29 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and interaction surface of the C-terminal domain from p47: a major p97-cofactor involved in SNARE disassembly. J.Mol.Biol., 311, 2001
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1RKV
| Structure of Phosphate complex of ThrH from Pseudomonas aeruginosa | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Singh, S.K, Yang, K, Subramanian, K, Karthikeyan, S, Huynh, T, Zhang, X, Phillips, M.A, Zhang, H. | 登録日 | 2003-11-23 | 公開日 | 2004-03-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity. J.Biol.Chem., 279, 2004
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6Z3A
| Mec1-Ddc2 (wild-type) in complex with AMP-PNP | 分子名称: | DNA damage checkpoint protein LCD1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase MEC1, ... | 著者 | Yates, L.A, Zhang, X. | 登録日 | 2020-05-19 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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6Z2W
| Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | 分子名称: | DNA damage checkpoint protein LCD1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Yates, L.A, Zhang, X. | 登録日 | 2020-05-18 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase. Nat.Struct.Mol.Biol., 28, 2021
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6Z2X
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6D2K
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5OQ4
| PQR309 - a Potent, Brain-Penetrant, Orally Bioavailable, pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology | 分子名称: | 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION | 著者 | Williams, R.L, Zhang, X. | 登録日 | 2017-08-10 | 公開日 | 2017-09-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine (PQR309), a Potent, Brain-Penetrant, Orally Bioavailable, Pan-Class I PI3K/mTOR Inhibitor as Clinical Candidate in Oncology. J. Med. Chem., 60, 2017
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1U2Z
| Crystal structure of histone K79 methyltransferase Dot1p from yeast | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Sawada, K, Yang, Z, Horton, J.R, Collins, R.E, Zhang, X, Cheng, X. | 登録日 | 2004-07-20 | 公開日 | 2004-09-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase J.Biol.Chem., 279, 2004
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1V92
| Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97 | 分子名称: | NSFL1 cofactor p47 | 著者 | Yuan, X, Simpson, P, Mckeown, C, Kondo, H, Uchiyama, K, Wallis, R, Dreveny, I, Keetch, C, Zhang, X, Robinson, C, Freemont, P, Matthews, S. | 登録日 | 2004-01-19 | 公開日 | 2004-04-06 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97 Embo J., 23, 2004
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3KH8
| Crystal structure of MaoC-like dehydratase from Phytophthora Capsici | 分子名称: | MaoC-like dehydratase | 著者 | Wang, H, Zhang, K, Guo, J, Zhou, Q, Zheng, X, Sun, F, Pang, H, Zhang, X. | 登録日 | 2009-10-30 | 公開日 | 2010-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of MaoC-like dehydratase from Phytophthora Capsici To be Published
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6D21
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1VAZ
| Solution structures of the p47 SEP domain | 分子名称: | NSFL1 cofactor p47 | 著者 | Yuan, X, Simpson, P, Mckeown, C, Kondo, H, Uchiyama, K, Wallis, R, Dreveny, I, Keetch, C, Zhang, X, Robinson, C, Freemont, P, Matthews, S. | 登録日 | 2004-02-20 | 公開日 | 2004-04-06 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97. Embo J., 23, 2004
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1SVU
| Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions | 分子名称: | Modification methylase HhaI, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | 著者 | Dong, A, Zhou, L, Zhang, X, Stickel, S, Roberts, R.J, Cheng, X. | 登録日 | 2004-03-30 | 公開日 | 2004-06-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions Biol.Chem., 385, 2004
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1WE1
| Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC6803 in complex with heme | 分子名称: | CHLORIDE ION, Heme oxygenase 1, ISOPROPYL ALCOHOL, ... | 著者 | Sugishima, M, Migita, C.T, Zhang, X, Yoshida, T, Fukuyama, K. | 登録日 | 2004-05-21 | 公開日 | 2004-12-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of heme oxygenase-1 from cyanobacterium Synechocystis sp. PCC 6803 in complex with heme Eur.J.Biochem., 271, 2004
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1JQE
| Crystal Structure Analysis of Human Histamine Methyltransferase (Ile105 Polymorphic Variant) Complexed with AdoHcy and Antimalarial Drug Quinacrine | 分子名称: | Histamine N-Methyltransferase, QUINACRINE, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X. | 登録日 | 2001-08-06 | 公開日 | 2002-08-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons. Structure, 9, 2001
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1JQD
| Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine | 分子名称: | HISTAMINE, Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Horton, J.R, Sawada, K, Nishibori, M, Zhang, X, Cheng, X. | 登録日 | 2001-08-06 | 公開日 | 2002-08-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons. Structure, 9, 2001
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1KHC
| Crystal Structure of the PWWP Domain of Mammalian DNA Methyltransferase Dnmt3b | 分子名称: | DNA cytosine-5 methyltransferase 3B2, UNKNOWN ATOM OR ION | 著者 | Qiu, C, Sawada, K, Zhang, X, Cheng, X. | 登録日 | 2001-11-29 | 公開日 | 2002-02-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds. Nat.Struct.Biol., 9, 2002
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1NGN
| Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 | 分子名称: | methyl-CpG binding protein MBD4 | 著者 | Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X. | 登録日 | 2002-12-17 | 公開日 | 2003-03-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4 J.Biol.Chem., 278, 2003
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6S8F
| Structure of nucleotide-bound Tel1/ATM | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1,Serine/threonine-protein kinase TEL1 | 著者 | Yates, L.A, Williams, R.M, Ayala, R, Zhang, X. | 登録日 | 2019-07-09 | 公開日 | 2019-10-30 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM Structure of Nucleotide-Bound Tel1ATMUnravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations. Structure, 28, 2020
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1MVX
| structure of the SET domain histone lysine methyltransferase Clr4 | 分子名称: | CRYPTIC LOCI REGULATOR 4, NICKEL (II) ION, SULFATE ION, ... | 著者 | Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M. | 登録日 | 2002-09-26 | 公開日 | 2002-10-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the SET domain histone lysine methyltransferase Clr4. Nat.Struct.Biol., 9, 2002
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1MVH
| structure of the SET domain histone lysine methyltransferase Clr4 | 分子名称: | Cryptic loci regulator 4, NICKEL (II) ION, SULFATE ION, ... | 著者 | Min, J.R, Zhang, X, Cheng, X.D, Grewal, S.I.S, Xu, R.-M. | 登録日 | 2002-09-25 | 公開日 | 2002-10-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the SET domain histone lysine methyltransferase Clr4. Nat.Struct.Biol., 9, 2002
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1FZX
| NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAAAAACGG | 分子名称: | 5'-D(*CP*CP*GP*TP*TP*TP*TP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*AP*AP*AP*AP*CP*GP*G)-3' | 著者 | MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P. | 登録日 | 2000-10-04 | 公開日 | 2001-03-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of an A-tract DNA bend. J.Mol.Biol., 306, 2001
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