6LR7
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7BQA
| Crystal structure of ASFV p35 | 分子名称: | 60 kDa polyprotein | 著者 | Li, G.B, Fu, D, Chen, C, Guo, Y. | 登録日 | 2020-03-24 | 公開日 | 2020-06-24 | 最終更新日 | 2021-05-05 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Crystal structure of the African swine fever virus structural protein p35 reveals its role for core shell assembly. Protein Cell, 11, 2020
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6KBD
| fused To-MtbCsm1 with 2dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A),CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), MAGNESIUM ION | 著者 | Li, T, Huo, Y, Jiang, T. | 登録日 | 2019-06-24 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity. Int.J.Biol.Macromol., 170, 2020
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6J2Q
| Yeast proteasome in Ub-accepted state (C1-b) | 分子名称: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | 著者 | Cong, Y. | 登録日 | 2019-01-02 | 公開日 | 2019-03-13 | 最終更新日 | 2019-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J30
| yeast proteasome in Ub-engaged state (C2) | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | 著者 | Cong, Y. | 登録日 | 2019-01-03 | 公開日 | 2019-03-20 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6J2N
| yeast proteasome in substrate-processing state (C3-b) | 分子名称: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | 著者 | Cong, Y. | 登録日 | 2019-01-02 | 公開日 | 2019-03-20 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structural Snapshots of 26S Proteasome Reveal Tetraubiquitin-Induced Conformations. Mol. Cell, 73, 2019
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6IN7
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7W2P
| Tudor domain of SMN in complex with a small molecule | 分子名称: | 2-[(4-fluorophenyl)methyl]-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),3(7)-dien-8-imine, MAGNESIUM ION, Survival motor neuron protein, ... | 著者 | Li, W, Arrowsmith, C.H, Edwards, A.M, Liu, Y, Min, J. | 登録日 | 2021-11-24 | 公開日 | 2022-10-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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6J9K
| Apo-AcrIIC2 | 分子名称: | AcrIIC2, MAGNESIUM ION | 著者 | Zhu, Y.L, Gao, A, Serganov, A, Gao, P. | 登録日 | 2019-01-23 | 公開日 | 2019-03-06 | 最終更新日 | 2022-03-23 | 実験手法 | X-RAY DIFFRACTION (2.234 Å) | 主引用文献 | Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins. Mol. Cell, 74, 2019
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7W30
| Tudor domain of SMN in complex with a small molecule | 分子名称: | 1,2-dimethylquinolin-4-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION | 著者 | Li, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Liu, Y, Min, J. | 登録日 | 2021-11-24 | 公開日 | 2022-10-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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6J9L
| FnoBH+AcrIIC2 | 分子名称: | AcrIIC2, HNH endonuclease family protein | 著者 | Zhu, Y.L, Gao, A, Serganov, A, Gao, P. | 登録日 | 2019-01-23 | 公開日 | 2019-03-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins. Mol. Cell, 74, 2019
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7BYF
| The crystal structure of mouse ORF10-Rae1-Nup98 complex | 分子名称: | 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ... | 著者 | Gao, P, Feng, H. | 登録日 | 2020-04-22 | 公開日 | 2021-03-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. Proc.Natl.Acad.Sci.USA, 117, 2020
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6J9N
| NmeHNH+AcrIIC3 | 分子名称: | AcrIIC3, CRISPR-associated endonuclease Cas9 | 著者 | Zhu, Y.L, Gao, A, Serganov, A, Gao, P. | 登録日 | 2019-01-23 | 公開日 | 2019-03-06 | 最終更新日 | 2022-03-23 | 実験手法 | X-RAY DIFFRACTION (2.606 Å) | 主引用文献 | Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins. Mol. Cell, 74, 2019
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6KEY
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7CJT
| Crystal Structure of SETDB1 Tudor domain in complexed with (R,R)-59 | 分子名称: | 2-[[(3~{R},5~{R})-1-methyl-5-(4-phenylmethoxyphenyl)piperidin-3-yl]amino]-3-prop-2-enyl-5~{H}-pyrrolo[3,2-d]pyrimidin-4-one, Histone-lysine N-methyltransferase SETDB1 | 著者 | Guo, Y.P, Liang, X, Mao, X, Wu, C, Luyi, H, Yang, S. | 登録日 | 2020-07-13 | 公開日 | 2021-04-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.474 Å) | 主引用文献 | Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain. Angew.Chem.Int.Ed.Engl., 60, 2021
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7CAJ
| Crystal structure of SETDB1 Tudor domain in complexed with Compound 2. | 分子名称: | 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-5H-pyrrolo[3,2-d]pyrimidin-4-one, Histone-lysine N-methyltransferase SETDB1 | 著者 | Guo, Y.P, Liang, X, Xin, M, Luyi, H, Chengyong, W, Yang, S.Y. | 登録日 | 2020-06-08 | 公開日 | 2021-04-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain. Angew.Chem.Int.Ed.Engl., 60, 2021
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6KPC
| Crystal structure of an agonist bound GPCR | 分子名称: | 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile, Cannabinoid receptor 2,Endolysin | 著者 | Li, X.T, Hua, T, Wu, L.J, Makriyannis, A, Wu, M, Liu, Z.J. | 登録日 | 2019-08-15 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures. Cell, 180, 2020
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7CPC
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7CPI
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7CQO
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7CQM
| PlsY grown in LCP soaked with selenourea for 22 min | 分子名称: | (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, Glycerol-3-phosphate acyltransferase, SULFATE ION, ... | 著者 | Luo, Z.P, Li, D.F. | 登録日 | 2020-08-11 | 公開日 | 2021-08-11 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Selenourea for experimental phasing of membrane protein crystals grown in lipid cubic phase Crystals, 12, 2022
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6L5M
| Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2 | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6LBC
| shrimp ferritin-T158R | 分子名称: | FE (III) ION, Ferritin | 著者 | Zhao, G, Chen, H, Zhang, T. | 登録日 | 2019-11-14 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions. Food Chem, 349, 2021
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6L5L
| Crystal structure of human DEAD-box RNA helicase DDX21 at apo state | 分子名称: | MAGNESIUM ION, Nucleolar RNA helicase 2 | 著者 | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | 登録日 | 2019-10-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6L5D
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