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6UER
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BU of 6uer by Molmil
Crystal form 2: Structure of TBP bound to C-C mismatch at pH 7
分子名称: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*CP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA-box-binding protein 1
著者Schumacher, M.A, Al-Hashimi, H.
登録日2019-09-22
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature, 587, 2020
7WCY
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BU of 7wcy by Molmil
Crystal Structure of H-2Kb with Cryptosporidium parvum gp40/15 epitope
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Wang, Y.L, Gao, M.H, Zhang, L.X, Fan, S.H.
登録日2021-12-20
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural Analyses of a Dominant Cryptosporidium parvum Epitope Presented by H-2K b Offer New Options To Combat Cryptosporidiosis.
Mbio, 14, 2023
6UEQ
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BU of 6ueq by Molmil
Structure of TBP bound to C-C mismatch containing TATA site
分子名称: DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*CP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), SULFATE ION, ...
著者Schumacher, M.A, Al-Hashimi, H.
登録日2019-09-22
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献DNA mismatches reveal conformational penalties in protein-DNA recognition.
Nature, 587, 2020
5A9W
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BU of 5a9w by Molmil
Structure of GDPCP BipA
分子名称: GTP-BINDING PROTEIN, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.
登録日2015-07-23
公開日2015-08-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
5H1T
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BU of 5h1t by Molmil
Complex structure of TRIM24 PHD-bromodomain and inhibitor 1
分子名称: DIMETHYL SULFOXIDE, Transcription intermediary factor 1-alpha, ZINC ION, ...
著者Liu, J.
登録日2016-10-11
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network
FEBS J., 284, 2017
3IOK
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BU of 3iok by Molmil
2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2
分子名称: 3-(6-{[(1S)-1-(4-fluorophenyl)ethyl]amino}pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine, Tyrosine-protein kinase JAK2
著者Zuccola, H.J, Ledeboer, M.W, Pierce, A.C.
登録日2009-08-14
公開日2009-11-10
最終更新日2013-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2.
Bioorg.Med.Chem.Lett., 19, 2009
5A9Y
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BU of 5a9y by Molmil
Structure of ppGpp BipA
分子名称: GTP-BINDING PROTEIN, GUANOSINE-5',3'-TETRAPHOSPHATE
著者Kumar, V, Chen, Y, Ero, R, Li, Z, Gao, Y.-G.
登録日2015-07-23
公開日2015-08-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structure of Bipa in GTP Form Bound to the Ratcheted Ribosome.
Proc.Natl.Acad.Sci.USA, 112, 2015
2WD4
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BU of 2wd4 by Molmil
Ascorbate Peroxidase as a heme oxygenase: w41A variant product with t-butyl peroxide
分子名称: 3-[2-[[3-(2-CARBOXYETHYL)-5-[[3-ETHENYL-4-METHYL-5-[(2-METHYLPROPAN-2-YL)OXY]-1H-PYRROL-2-YL]METHYL]-4-METHYL-1H-PYRROL -2-YL]METHYL]-5-[(Z)-(4-ETHENYL-3-METHYL-5-OXO-PYRROL-2-YLIDENE)METHYL]-4-METHYL-1H-PYRROL-3-YL]PROPANOIC ACID, ASCORBATE PEROXIDASE, FE (III) ION, ...
著者Badyal, S.K, Metcalfe, C.L, Gumiero, A, Raven, E.L, Moody, P.C.E.
登録日2009-03-19
公開日2009-04-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Evidence for Heme Oxygenase Activity in a Heme Peroxidase.
Biochemistry, 48, 2009
2KHP
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BU of 2khp by Molmil
Solution structure of Glutaredoxin from Brucella melitensis
分子名称: GLUTAREDOXIN
著者Zheng, S, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-04-10
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens.
Acta Crystallogr.,Sect.F, 67, 2011
3KK1
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BU of 3kk1 by Molmil
HIV-1 reverse transcriptase-DNA complex with nuceotide inhibitor GS-9148-diphosphate bound in nucleotide site
分子名称: 5'-D(*A*TP*GP*GP*TP*GP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', 5'-D(*AP*CP*A*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*(DOC))-3', MAGNESIUM ION, ...
著者Lansdon, E.B.
登録日2009-11-04
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.
J.Mol.Biol., 397, 2010
8CDT
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BU of 8cdt by Molmil
Crystal structure of the xNup93-Nb2t VHH antibody
分子名称: 15-Nup93 tracking VHH antibody, GLYCEROL
著者Guttler, T, Colom, M.S, Gorlich, D.
登録日2023-02-01
公開日2024-02-21
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 43, 2024
7DOK
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BU of 7dok by Molmil
Structure of COVID-19 RNA-dependent RNA polymerase (extended conformation) bound to penciclovir
分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
著者Li, Z, Yu, X.
登録日2020-12-14
公開日2021-12-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural basis for repurpose and design of nucleotide drugs for treating COVID-19
To Be Published
7DOI
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BU of 7doi by Molmil
Structure of COVID-19 RNA-dependent RNA polymerase bound to penciclovir.
分子名称: MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ...
著者Li, Z, Yu, X.
登録日2020-12-14
公開日2021-12-15
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for repurpose and design of nucleotide drugs for treating COVID-19
To Be Published
5XEA
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BU of 5xea by Molmil
Structure of Thogoto virus envelope glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ...
著者Peng, R, Shi, Y, Qi, J, Gao, G.F.
登録日2017-04-03
公開日2017-10-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Structures of human-infecting Thogotovirus fusogens support a common ancestor with insect baculovirus
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3KK3
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BU of 3kk3 by Molmil
HIV-1 reverse transcriptase-DNA complex with GS-9148 terminated primer
分子名称: 5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*C*(URT))-3', 5'-D(*AP*TP*GP*GP*TP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ...
著者Lansdon, E.B.
登録日2009-11-04
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.
J.Mol.Biol., 397, 2010
8CDS
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BU of 8cds by Molmil
Crystal structure of the xhNup93-Nb4i VHH antibody
分子名称: 1,2-ETHANEDIOL, 5-Nup93 inhibitory VHH antibody, DI(HYDROXYETHYL)ETHER
著者Guttler, T, Colom, M.S, Gorlich, D.
登録日2023-02-01
公開日2024-02-21
最終更新日2024-06-12
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 43, 2024
6ZZB
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BU of 6zzb by Molmil
Crystal structure of the Eimeria tenella surface antigen protein SAG19
分子名称: SAG family member (Sag19), SULFATE ION
著者Dix, S.R, Rice, D.W.
登録日2020-08-04
公開日2021-03-24
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.322 Å)
主引用文献The structure of a major surface antigen SAG19 from Eimeria tenella unifies the Eimeria SAG family.
Commun Biol, 4, 2021
3KJV
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BU of 3kjv by Molmil
HIV-1 reverse transcriptase in complex with DNA
分子名称: 5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*(DOC))-3', 5'-D(*AP*TP*GP*GP*TP*GP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3', MAGNESIUM ION, ...
著者Lansdon, E.B.
登録日2009-11-03
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.
J.Mol.Biol., 397, 2010
7E77
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BU of 7e77 by Molmil
The structure of cytosolic TaPGI
分子名称: Glucose-6-phosphate isomerase
著者Gao, F, Liu, C.M.
登録日2021-02-25
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
7E78
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BU of 7e78 by Molmil
the structure of cytosolic TaPGI with substrate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, Glucose-6-phosphate isomerase
著者Gao, F, Liu, C.M.
登録日2021-02-25
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
7E76
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BU of 7e76 by Molmil
The structure of chloroplastic TaPGI
分子名称: Glucose-6-phosphate isomerase
著者Gao, F, Liu, C.M.
登録日2021-02-25
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
6B09
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BU of 6b09 by Molmil
Crystal structure of HsNUDT16 in complex with diADPR (soaked)
分子名称: CHLORIDE ION, MAGNESIUM ION, SODIUM ION, ...
著者Thirawatananond, P, Gabelli, S.B.
登録日2017-09-14
公開日2019-01-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.
Sci Rep, 9, 2019
3KLN
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BU of 3kln by Molmil
Vibrio cholerae VpsT
分子名称: Transcriptional regulator, LuxR family
著者Krasteva, P.V, Navarro, V.A.S, Sondermann, H.
登録日2009-11-08
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.078 Å)
主引用文献Vibrio cholerae VpsT Regulates Matrix Production and Motility by Directly Sensing Cyclic di-GMP.
Science, 327, 2010
7K4M
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BU of 7k4m by Molmil
Crystal structure of MetAP2 Modified Hemoglobin S
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Musayev, F.N, Safo, M.K, Light, D.R.
登録日2020-09-15
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease.
Blood Adv, 5, 2021
1MAT
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BU of 1mat by Molmil
STRUCTURE OF THE COBALT-DEPENDENT METHIONINE AMINOPEPTIDASE FROM ESCHERICHIA COLI: A NEW TYPE OF PROTEOLYTIC ENZYME
分子名称: COBALT (II) ION, METHIONYL AMINOPEPTIDASE
著者Roderick, S.L, Matthews, B.W.
登録日1992-12-02
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme.
Biochemistry, 32, 1993

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