1KGM
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![BU of 1kgm by Molmil](/molmil-images/mine/1kgm) | SOLUTION STRUCTURE OF THE SMALL SERINE PROTEASE INHIBITOR SGCI | Descriptor: | SERINE PROTEASE INHIBITOR I | Authors: | Gaspari, Z, Patthy, A, Graf, L, Perczel, A. | Deposit date: | 2001-11-28 | Release date: | 2001-12-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Comparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregaria. Eur.J.Biochem., 269, 2002
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1KJ0
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![BU of 1kj0 by Molmil](/molmil-images/mine/1kj0) | SOLUTION STRUCTURE OF THE SMALL SERINE PROTEASE INHIBITOR SGTI | Descriptor: | SERINE PROTEASE INHIBITOR I | Authors: | Gaspari, Z, Patthy, A, Graf, L, Perczel, A. | Deposit date: | 2001-12-04 | Release date: | 2001-12-12 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Comparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregaria. Eur.J.Biochem., 269, 2002
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4D07
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![BU of 4d07 by Molmil](/molmil-images/mine/4d07) | DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5a tail | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT (II) ION, DYNEIN LIGHT CHAIN 2, ... | Authors: | Bodor, A, Radnai, L, Hetenyi, C, Rapali, P, Lang, A, Kover, K.E, Perczel, A, Wahlgren, W.Y, Katona, G, Nyitray, L. | Deposit date: | 2014-04-24 | Release date: | 2014-10-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Dynll2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5A Tail that Has Structural Plasticity. Biochemistry, 53, 2014
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1KIO
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![BU of 1kio by Molmil](/molmil-images/mine/1kio) | SOLUTION STRUCTURE OF THE SMALL SERINE PROTEASE INHIBITOR SGCI[L30R, K31M] | Descriptor: | SERINE PROTEASE INHIBITOR I | Authors: | Gaspari, Z, Patthy, A, Graf, L, Perczel, A. | Deposit date: | 2001-12-03 | Release date: | 2001-12-12 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Comparative structure analysis of proteinase inhibitors from the desert locust, Schistocerca gregaria. Eur.J.Biochem., 269, 2002
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2MJ9
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![BU of 2mj9 by Molmil](/molmil-images/mine/2mj9) | Designed Exendin-4 analogues | Descriptor: | Exendin-4 | Authors: | Rovo, P, Farkas, V, Straner, P, Szabo, M, Jermendy, A, Hegyi, O, Toth, G.K, Perczel, A. | Deposit date: | 2013-12-30 | Release date: | 2014-06-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Rational design of alpha-helix-stabilized exendin-4 analogues. Biochemistry, 53, 2014
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7QUN
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![BU of 7qun by Molmil](/molmil-images/mine/7qun) | CryoEM structure of mammalian AAP in complex with Meropenem | Descriptor: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Acylamino-acid-releasing enzyme | Authors: | Kiss-Szeman, A.J, Harmat, V, Straner, P, Jakli, I, Menyhard, K.D, Masiulis, S, Perczel, A. | Deposit date: | 2022-01-18 | Release date: | 2022-11-16 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase-meropenem complex. Chem Sci, 13, 2022
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7PX8
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![BU of 7px8 by Molmil](/molmil-images/mine/7px8) | CryoEM structure of mammalian acylaminoacyl-peptidase | Descriptor: | Acylamino-acid-releasing enzyme | Authors: | Kiss-Szeman, A.J, Harmat, V, Menyhard, D.K, Straner, P, Jakli, I, Hosogi, N, Perczel, A. | Deposit date: | 2021-10-08 | Release date: | 2022-05-25 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad. Chem Sci, 13, 2022
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2F91
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![BU of 2f91 by Molmil](/molmil-images/mine/2f91) | 1.2A resolution structure of a crayfish trypsin complexed with a peptide inhibitor, SGTI | Descriptor: | CADMIUM ION, CHLORIDE ION, Serine protease inhibitor I/II, ... | Authors: | Fodor, K, Harmat, V, Hetenyi, C, Kardos, J, Antal, J, Perczel, A, Patthy, A, Katona, G, Graf, L. | Deposit date: | 2005-12-05 | Release date: | 2006-04-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Enzyme:Substrate Hydrogen Bond Shortening during the Acylation Phase of Serine Protease Catalysis. Biochemistry, 45, 2006
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1KZ5
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1KZ2
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![BU of 1kz2 by Molmil](/molmil-images/mine/1kz2) | Solution structure of the third helix of Antennapedia homeodomain derivative [W6F,W14F] | Descriptor: | Antennapedia protein | Authors: | Czajlik, A, Mesko, E, Penke, B, Perczel, A. | Deposit date: | 2002-02-06 | Release date: | 2002-02-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Investigation of penetratin peptides. Part 1. The environment dependent conformational properties of penetratin and two of its derivatives. J.Pept.Sci., 8, 2002
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1KZ0
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8Q34
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![BU of 8q34 by Molmil](/molmil-images/mine/8q34) | Crystal structure of the first bromodomain of human BRD4 in complex with the ligand ZZ001229a | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(1~{H}-imidazo[4,5-b]pyridin-2-ylmethyl)-3-(3-methyl-1,2-diazirin-3-yl)propanamide | Authors: | MacLean, E.M, Gao, Q, Williams, E, Balcomb, B.H, von Delft, F, Bajusz, D, Keeley, A, Abranyi-Balogh, P, Koekemoer, L, Keseru, G.M. | Deposit date: | 2023-08-03 | Release date: | 2024-02-07 | Last modified: | 2024-08-14 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Mapping protein binding sites by photoreactive fragment pharmacophores. Commun Chem, 7, 2024
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8ONQ
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7ARX
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![BU of 7arx by Molmil](/molmil-images/mine/7arx) | Crystal structure of the catalytic fragment of masp-1 in complex with SFMI1 | Descriptor: | DI(HYDROXYETHYL)ETHER, Mannan-binding lectin serine protease 1, SFMI1 - Sunflower MASP1 inhibitor | Authors: | Durvanger, Z, Harmat, V, Dobo, J, Megyeri, M. | Deposit date: | 2020-10-26 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides. Acs Chem.Biol., 17, 2022
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8QWU
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![BU of 8qwu by Molmil](/molmil-images/mine/8qwu) | |
8QWV
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![BU of 8qwv by Molmil](/molmil-images/mine/8qwv) | |
8QWW
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![BU of 8qww by Molmil](/molmil-images/mine/8qww) | |
1VVE
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![BU of 1vve by Molmil](/molmil-images/mine/1vve) | |
1VVD
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![BU of 1vvd by Molmil](/molmil-images/mine/1vvd) | |
1XA5
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![BU of 1xa5 by Molmil](/molmil-images/mine/1xa5) | Structure of Calmodulin in complex with KAR-2, a bis-indol alkaloid | Descriptor: | 3"-(BETA-CHLOROETHYL)-2",4"-DIOXO-3, 5"-SPIRO-OXAZOLIDINO-4-DEACETOXY-VINBLASTINE, CALCIUM ION, ... | Authors: | Horvath, I, Harmat, V, Hlavanda, E, Naray-Szabo, G, Ovadi, J. | Deposit date: | 2004-08-25 | Release date: | 2004-12-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug J.Biol.Chem., 280, 2005
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1VVC
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8ANH
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8ANM
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8ANN
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![BU of 8ann by Molmil](/molmil-images/mine/8ann) | |
8ANL
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![BU of 8anl by Molmil](/molmil-images/mine/8anl) | |