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6LVK
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BU of 6lvk by Molmil
Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative
Descriptor: Fibroblast growth factor receptor 2, N-ethyl-2-[[4-[[4-(4-methylpiperazin-1-yl)-3-(2-morpholin-4-ylethoxy)phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide, SULFATE ION
Authors:Echizen, Y, Amano, Y, Tateishi, Y.
Deposit date:2020-02-04
Release date:2020-04-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2.
Bioorg.Med.Chem., 28, 2020
6KIP
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BU of 6kip by Molmil
Crystal structure of PTPRD phosphatase domain in complex with Liprin-alpha3 tandem SAM domains
Descriptor: Liprin-alpha-3, Receptor-type tyrosine-protein phosphatase delta
Authors:Wakita, M, Yamagata, A, Fukai, S.
Deposit date:2019-07-19
Release date:2020-02-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:Structural insights into selective interaction between type IIa receptor protein tyrosine phosphatases and Liprin-alpha.
Nat Commun, 11, 2020
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