7DTN
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6IUJ
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![BU of 6iuj by Molmil](/molmil-images/mine/6iuj) | Crystal structure of GH30 xylanase B from Talaromyces cellulolyticus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GH30 Xylanase B, ... | Authors: | Nakamichi, Y, Watanabe, M, Inoue, H. | Deposit date: | 2018-11-28 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and functional characterization of a bifunctional GH30-7 xylanase B from the filamentous fungusTalaromyces cellulolyticus. J. Biol. Chem., 294, 2019
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3WUX
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![BU of 3wux by Molmil](/molmil-images/mine/3wux) | Crystal structure of unsaturated glucuronyl hydrolase mutant D115N/K370S from Streptococcus agalactiae | Descriptor: | 1,2-ETHANEDIOL, Unsaturated chondroitin disaccharide hydrolase | Authors: | Nakamichi, Y, Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | Deposit date: | 2014-05-08 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.792 Å) | Cite: | Crystal structure of unsaturated glucuronyl hydrolase mutant D115N/K370S from Streptococcus agalactiae to be published
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6KRN
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![BU of 6krn by Molmil](/molmil-images/mine/6krn) | Crystal structure of GH30 xylanase B from Talaromyces cellulolyticus expressed by Pichia pastoris in complex with aldotriuronic acid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, Mating factor alpha,GH30 Xylanase B, ... | Authors: | Nakamichi, Y, Watanabe, M, Inoue, H. | Deposit date: | 2019-08-22 | Release date: | 2020-06-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.653 Å) | Cite: | Substrate recognition by a bifunctional GH30-7 xylanase B from Talaromyces cellulolyticus. Febs Open Bio, 10, 2020
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2ZJD
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![BU of 2zjd by Molmil](/molmil-images/mine/2zjd) | Crystal Structure of LC3-p62 complex | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B precursor, undecameric peptide from Sequestosome-1 | Authors: | Ichimura, Y, Kumanomidou, T, Sou, Y, Mizushima, T, Ezaki, J, Ueno, T, Kominami, E, Yamane, T, Tanaka, K, Komatsu, M. | Deposit date: | 2008-03-05 | Release date: | 2008-06-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structural Basis for Sorting Mechanism of p62 in Selective Autophagy J.Biol.Chem., 283, 2008
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3WIW
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![BU of 3wiw by Molmil](/molmil-images/mine/3wiw) | Crystal structure of unsaturated glucuronyl hydrolase specific for heparin | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glycosyl hydrolase family 88 | Authors: | Nakamichi, Y, Mikami, B, Murata, K, Hashimoto, W. | Deposit date: | 2013-09-26 | Release date: | 2014-01-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of a bacterial unsaturated glucuronyl hydrolase with specificity for heparin. J.Biol.Chem., 289, 2014
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3WVX
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3WVY
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![BU of 3wvy by Molmil](/molmil-images/mine/3wvy) | Structure of D48A hen egg white lysozyme in complex with (GlcNAc)4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C | Authors: | Kawaguchi, Y, Yoneda, K, Araki, T. | Deposit date: | 2014-06-11 | Release date: | 2015-06-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | The role of Asp48 in the hydrogen bonding network involving Asp52 of hen egg white lysozyme TO BE PUBLISHED
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3WYH
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2ZJW
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![BU of 2zjw by Molmil](/molmil-images/mine/2zjw) | Crystal structure of human CK2 alpha complexed with Ellagic acid | Descriptor: | 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione, Casein kinase II subunit alpha | Authors: | Sekiguchi, Y, Kinoshita, T, Nakaniwa, T, Tada, T. | Deposit date: | 2008-03-11 | Release date: | 2009-03-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid Bioorg.Med.Chem.Lett., 19, 2009
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7E9S
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![BU of 7e9s by Molmil](/molmil-images/mine/7e9s) | Archaeal oligosaccharyltransferase AglB from Archaeoglobus fulgidus in complex with an inhibitory peptide and a dolichol-phosphate | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL (7Z)-TETRADEC-7-ENOATE, DI(HYDROXYETHYL)ETHER, Dolichyl-phosphooligosaccharide-protein glycotransferase 3, ... | Authors: | Taguchi, Y, Hirata, K, Kohda, D. | Deposit date: | 2021-03-05 | Release date: | 2021-09-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon. Commun Biol, 4, 2021
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7E9U
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![BU of 7e9u by Molmil](/molmil-images/mine/7e9u) | Trehalase of Arabidopsis thaliana | Descriptor: | GLYCEROL, PHOSPHATE ION, SODIUM ION, ... | Authors: | Taguchi, Y, Saburi, W, Yu, J, Imai, R, Yao, M, Mori, H. | Deposit date: | 2021-03-05 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | pH-dependent alteration of substrate specificity of plant trehalase and its molecular mechanism To Be Published
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7E9X
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![BU of 7e9x by Molmil](/molmil-images/mine/7e9x) | Trehalase of Arabidopsis thaliana acid mutant -D380A | Descriptor: | GLYCEROL, Trehalase | Authors: | Taguchi, Y, Saburi, W, Yu, J, Imai, R, Yao, M, Mori, H. | Deposit date: | 2021-03-05 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | pH-dependent alteration of substrate specificity of plant trehalase and its molecular mechanism To Be Published
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7EAW
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![BU of 7eaw by Molmil](/molmil-images/mine/7eaw) | Trehalase of Arabidopsis thaliana acid mutant -D380A trehalose complex | Descriptor: | GLYCEROL, Trehalase, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | Authors: | Taguchi, Y, Saburi, W, Yu, J, Imai, R, Yao, M, Mori, H. | Deposit date: | 2021-03-08 | Release date: | 2022-03-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | pH-dependent alteration of substrate specificity of plant trehalase and its molecular mechanism To Be Published
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7YRU
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![BU of 7yru by Molmil](/molmil-images/mine/7yru) | ALK2 antibody complex | Descriptor: | Activin receptor type-1, antibody heavy chain, antibody light chain | Authors: | Kawaguchi, Y, Nakamura, K, Suzuki, M, Tsuji, S, Katagiri, T. | Deposit date: | 2022-08-10 | Release date: | 2023-05-17 | Last modified: | 2023-06-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders. Nat Commun, 14, 2023
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6LVL
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![BU of 6lvl by Molmil](/molmil-images/mine/6lvl) | Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative | Descriptor: | Fibroblast growth factor receptor 2, N-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide, SULFATE ION | Authors: | Echizen, Y, Tateishi, Y, Amano, Y. | Deposit date: | 2020-02-04 | Release date: | 2020-04-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. Bioorg.Med.Chem., 28, 2020
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7DHL
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![BU of 7dhl by Molmil](/molmil-images/mine/7dhl) | Crystal structure of FGFR3 in complex with pyrimidine derivative | Descriptor: | 5-[2-(3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine, Fibroblast growth factor receptor 3 | Authors: | Echizen, Y, Tateishi, Y, Amano, Y. | Deposit date: | 2020-11-16 | Release date: | 2021-02-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency. Bioorg.Med.Chem., 33, 2021
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5B1N
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![BU of 5b1n by Molmil](/molmil-images/mine/5b1n) | DHp domain structure of EnvZ from Escherichia coli | Descriptor: | Osmolarity sensor protein EnvZ | Authors: | Okajima, T, Eguchi, Y, Tochio, N, Inukai, Y, Shimizu, R, Ueda, S, Shinya, S, Kigawa, T, Fukamizo, T, Igarashi, M, Utsumi, R. | Deposit date: | 2015-12-09 | Release date: | 2016-12-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Angucycline antibiotic waldiomycin recognizes common structural motif conserved in bacterial histidine kinases J. Antibiot., 70, 2017
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5AX7
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![BU of 5ax7 by Molmil](/molmil-images/mine/5ax7) | yeast pyruvyltransferase Pvg1p | Descriptor: | Pyruvyl transferase 1, ZINC ION | Authors: | Kanekiyo, M, Yoritsune, K, Yoshinaga, S, Higuchi, Y, Takegawa, K, Kakuta, Y. | Deposit date: | 2015-07-16 | Release date: | 2016-06-08 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | A rationally engineered yeast pyruvyltransferase Pvg1p introduces sialylation-like properties in neo-human-type complex oligosaccharide Sci Rep, 6, 2016
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6KRV
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![BU of 6krv by Molmil](/molmil-images/mine/6krv) | Crystal structure of mouse IgG2b Fc complexed with B domain of Protein A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-2B chain C region, ... | Authors: | Taniguchi, Y, Satoh, T, Yagi, H, Kato, K. | Deposit date: | 2019-08-22 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | On-Membrane Dynamic Interplay between Anti-GM1 IgG Antibodies and Complement Component C1q. Int J Mol Sci, 21, 2019
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5SIC
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6LVM
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![BU of 6lvm by Molmil](/molmil-images/mine/6lvm) | Crystal structure of FGFR3 in complex with pyrimidine derivative | Descriptor: | 2-[[5-[2-(3,5-dimethoxyphenyl)ethyl]-2-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]pyrimidin-4-yl]amino]-N-ethyl-benzenesulfonamide, Fibroblast growth factor receptor 3 | Authors: | Echizen, Y, Tateishi, Y, Amano, Y. | Deposit date: | 2020-02-04 | Release date: | 2020-04-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. Bioorg.Med.Chem., 28, 2020
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6LVK
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![BU of 6lvk by Molmil](/molmil-images/mine/6lvk) | Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative | Descriptor: | Fibroblast growth factor receptor 2, N-ethyl-2-[[4-[[4-(4-methylpiperazin-1-yl)-3-(2-morpholin-4-ylethoxy)phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide, SULFATE ION | Authors: | Echizen, Y, Amano, Y, Tateishi, Y. | Deposit date: | 2020-02-04 | Release date: | 2020-04-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. Bioorg.Med.Chem., 28, 2020
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5B1O
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![BU of 5b1o by Molmil](/molmil-images/mine/5b1o) | DHp domain structure of EnvZ P248A mutant | Descriptor: | Osmolarity sensor protein EnvZ | Authors: | Okajima, T, Eguchi, Y, Tochio, N, Inukai, Y, Shimizu, R, Ueda, S, Shinya, S, Kigawa, T, Fukamizo, T, Igarashi, M, Utsumi, R. | Deposit date: | 2015-12-09 | Release date: | 2016-12-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Angucycline antibiotic waldiomycin recognizes common structural motif conserved in bacterial histidine kinases J. Antibiot., 70, 2017
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2RDV
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![BU of 2rdv by Molmil](/molmil-images/mine/2rdv) | |