2CW7
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![BU of 2cw7 by Molmil](/molmil-images/mine/2cw7) | Crystal structure of intein homing endonuclease II | Descriptor: | Endonuclease PI-PkoII, SULFATE ION | Authors: | Matsumura, H, Takahashi, H, Inoue, T, Hashimoto, H, Nishioka, M, Fujiwara, S, Takagi, M, Imanaka, T, Kai, Y. | Deposit date: | 2005-06-17 | Release date: | 2006-04-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1 Proteins, 63, 2006
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2CW8
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![BU of 2cw8 by Molmil](/molmil-images/mine/2cw8) | Crystal structure of intein homing endonuclease II | Descriptor: | Endonuclease PI-PkoII, GLYCEROL, SULFATE ION | Authors: | Matsumura, H, Takahashi, H, Inoue, T, Hashimoto, H, Nishioka, M, Fujiwara, S, Takagi, M, Imanaka, T, Kai, Y. | Deposit date: | 2005-06-17 | Release date: | 2006-04-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1 Proteins, 63, 2006
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1IE6
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![BU of 1ie6 by Molmil](/molmil-images/mine/1ie6) | SOLUTION STRUCTURE OF IMPERATOXIN A | Descriptor: | IMPERATOXIN A | Authors: | Lee, C.W, Takeuchi, K, Takahashi, H, Sato, K, Shimada, I, Kim, D.H, Kim, J.I. | Deposit date: | 2001-04-07 | Release date: | 2003-06-10 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Molecular basis of the high-affinity activation of type 1 ryanodine receptors by imperatoxin A. Biochem.J., 377, 2004
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3VV1
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![BU of 3vv1 by Molmil](/molmil-images/mine/3vv1) | Crystal Structure of Caenorhabditis elegans galectin LEC-6 | Descriptor: | MAGNESIUM ION, Protein LEC-6, beta-D-galactopyranose-(1-4)-alpha-L-fucopyranose | Authors: | Makyio, H, Takeuchi, T, Tamura, M, Nishiyama, K, Takahashi, H, Natsugari, H, Arata, Y, Kasai, K, Yamada, Y, Wakatsuki, S, Kato, R. | Deposit date: | 2012-07-10 | Release date: | 2013-05-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of preferential binding of fucose-containing saccharide by the Caenorhabditis elegans galectin LEC-6 Glycobiology, 23, 2013
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5YKY
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![BU of 5yky by Molmil](/molmil-images/mine/5yky) | Crystal Structure of Cross-Linked Tetragonal Hen Egg White Lysozyme Soaked with 10 mM Rose Bengal and 10mM H2PtCl6 | Descriptor: | CHLORIDE ION, Lysozyme C, PLATINUM (II) ION, ... | Authors: | Tabe, H, Takahashi, H, Shimoi, T, Abe, S, Ueno, T, Yamada, Y. | Deposit date: | 2017-10-16 | Release date: | 2018-09-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Photocatalytic hydrogen evolution systems constructed in cross-linked porous protein crystals Appl Catal B, 237, 2018
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7Y8P
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![BU of 7y8p by Molmil](/molmil-images/mine/7y8p) | Crystal structure of 4'-selenoRNA duplex | Descriptor: | COBALT HEXAMMINE(III), RNA (5'-R(*GP*GP*AP*(IKS)P*(ILK)P*(IKS)P*GP*AP*GP*UP*CP*C)-3') | Authors: | Kondo, J, Minakawa, N, Ohta, M, Takahashi, H, Tarashima, N. | Deposit date: | 2022-06-24 | Release date: | 2023-05-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Synthesis and properties of fully-modified 4'-selenoRNA, an endonuclease-resistant RNA analog. Bioorg.Med.Chem., 76, 2022
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1US5
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![BU of 1us5 by Molmil](/molmil-images/mine/1us5) | PUTATIVE GLUR0 LIGAND BINDING CORE WITH L-GLUTAMATE | Descriptor: | 1,2-ETHANEDIOL, GLUTAMIC ACID, PUTATIVE GLUR0 LIGAND BINDING CORE | Authors: | Tahirov, T.H, Inagaki, E. | Deposit date: | 2003-11-18 | Release date: | 2003-11-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the Thermus Thermophilus Putative Periplasmic Glutamate/Glutamine-Binding Protein Acta Crystallogr.,Sect.D, 60, 2004
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6LUR
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![BU of 6lur by Molmil](/molmil-images/mine/6lur) | |
5B83
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![BU of 5b83 by Molmil](/molmil-images/mine/5b83) | |
9BA4
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![BU of 9ba4 by Molmil](/molmil-images/mine/9ba4) | Full-length cross-linked Contactin 2 (CNTN2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-2 | Authors: | Liu, J.L, Fan, S.F, Ren, G.R, Rudenko, G.R. | Deposit date: | 2024-04-03 | Release date: | 2024-07-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Molecular mechanism of contactin 2 homophilic interaction. Structure, 2024
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9BA5
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![BU of 9ba5 by Molmil](/molmil-images/mine/9ba5) | |
8IIA
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![BU of 8iia by Molmil](/molmil-images/mine/8iia) | |
4K60
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![BU of 4k60 by Molmil](/molmil-images/mine/4k60) | Crystal Structure of Human Chymase in Complex with Fragment 6-bromo-1,3-dihydro-2H-indol-2-one | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-bromo-1,3-dihydro-2H-indol-2-one, Chymase, ... | Authors: | Collins, B.K, Padyana, A.K. | Deposit date: | 2013-04-15 | Release date: | 2013-05-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. J.Med.Chem., 56, 2013
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4K69
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![BU of 4k69 by Molmil](/molmil-images/mine/4k69) | Crystal Structure of Human Chymase in Complex with Fragment Linked Benzimidazolone Inhibitor: (3S)-3-{3-[(6-bromo-2-oxo-2,3-dihydro-1H-indol-4-yl)methyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}hexanoic acid | Descriptor: | (3S)-3-{3-[(6-bromo-2-oxo-2,3-dihydro-1H-indol-4-yl)methyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}hexanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, ... | Authors: | Collins, B.K, Padyana, A.K. | Deposit date: | 2013-04-15 | Release date: | 2013-05-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. J.Med.Chem., 56, 2013
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4K5Z
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![BU of 4k5z by Molmil](/molmil-images/mine/4k5z) | Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-chloro-2,3-dihydro-1H-isoindol-1-one | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-2,3-dihydro-1H-isoindol-1-one, Chymase, ... | Authors: | Collins, B.K, Padyana, A.K. | Deposit date: | 2013-04-15 | Release date: | 2013-05-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. J.Med.Chem., 56, 2013
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3S0N
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![BU of 3s0n by Molmil](/molmil-images/mine/3s0n) | Crystal Structure of Human Chymase with Benzimidazolone Inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-{3-[(4-methyl-1-benzothiophen-3-yl)methyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}butanoic acid, Chymase, ... | Authors: | Qian, K.C, Farrow, N.A, Padyana, A.K. | Deposit date: | 2011-05-13 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P(1)) region. Bioorg.Med.Chem.Lett., 21, 2011
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5WXI
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![BU of 5wxi by Molmil](/molmil-images/mine/5wxi) | EarP bound with dTDP-rhamnose (soaked) | Descriptor: | 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, BETA-MERCAPTOETHANOL, EarP, ... | Authors: | Sengoku, T, Yokoyama, S, Yanagisawa, T. | Deposit date: | 2017-01-07 | Release date: | 2018-02-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP Nat. Chem. Biol., 14, 2018
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5WXJ
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![BU of 5wxj by Molmil](/molmil-images/mine/5wxj) | Apo EarP | Descriptor: | BETA-MERCAPTOETHANOL, EarP, GLYCEROL, ... | Authors: | Sengoku, T, Yokoyama, S, Yanagisawa, T. | Deposit date: | 2017-01-07 | Release date: | 2018-02-28 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP Nat. Chem. Biol., 14, 2018
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5WXK
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![BU of 5wxk by Molmil](/molmil-images/mine/5wxk) | EarP bound with domain I of EF-P | Descriptor: | BETA-MERCAPTOETHANOL, EarP, Elongation factor P, ... | Authors: | Sengoku, T, Yokoyama, S, Yanagisawa, T. | Deposit date: | 2017-01-07 | Release date: | 2018-02-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP Nat. Chem. Biol., 14, 2018
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7XMC
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![BU of 7xmc by Molmil](/molmil-images/mine/7xmc) | Cryo-EM structure of Cytochrome bo3 from Escherichia coli, apo structure with DMSO | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | Authors: | Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. | Deposit date: | 2022-04-25 | Release date: | 2022-12-21 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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7XMD
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![BU of 7xmd by Molmil](/molmil-images/mine/7xmd) | Cryo-EM structure of Cytochrome bo3 from Escherichia coli, the structure complexed with an allosteric inhibitor N4 | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, COPPER (II) ION, Cytochrome bo(3) ubiquinol oxidase subunit 1, ... | Authors: | Nishida, Y, Shigematsu, H, Iwamoto, T, Takashima, S, Shintani, Y. | Deposit date: | 2022-04-25 | Release date: | 2022-12-21 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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7XMA
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![BU of 7xma by Molmil](/molmil-images/mine/7xma) | Crystal structure of Bovine heart cytochrome c oxidase, apo structure with DMSO | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Takashima, S, Shintani, Y. | Deposit date: | 2022-04-25 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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7XMB
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![BU of 7xmb by Molmil](/molmil-images/mine/7xmb) | Crystal structure of Bovine heart cytochrome c oxidase, the structure complexed with an allosteric inhibitor T113 | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Nishida, Y, Shinzawa-Itoh, K, Mizuno, N, Kumasaka, T, Yoshikawa, S, Tsukihara, T, Shintani, Y, Takashima, S. | Deposit date: | 2022-04-25 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat Commun, 13, 2022
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3GI3
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![BU of 3gi3 by Molmil](/molmil-images/mine/3gi3) | Crystal structure of a N-Phenyl-N'-Naphthylurea analog in complex with p38 MAP kinase | Descriptor: | Mitogen-activated protein kinase 14, N-{5-tert-butyl-2-methoxy-3-[({4-[6-(morpholin-4-ylmethyl)pyridin-3-yl]naphthalen-1-yl}carbamoyl)amino]phenyl}methanesulfonamide | Authors: | Qian, K.C. | Deposit date: | 2009-03-05 | Release date: | 2009-10-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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4K2Y
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![BU of 4k2y by Molmil](/molmil-images/mine/4k2y) | Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-chloro-1,3-dihydro-2H-indol-2-one | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-1,3-dihydro-2H-indol-2-one, Chymase, ... | Authors: | Collins, B.K, Padyana, A.K. | Deposit date: | 2013-04-09 | Release date: | 2013-05-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. J.Med.Chem., 56, 2013
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