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1I94
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BU of 1i94 by Molmil
CRYSTAL STRUCTURES OF THE SMALL RIBOSOMAL SUBUNIT WITH TETRACYCLINE, EDEINE AND IF3
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
1I97
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BU of 1i97 by Molmil
CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TETRACYCLINE
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
1FVH
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BU of 1fvh by Molmil
CRYSTAL STRUCTURE ANALYSIS OF NEURONAL SEC1 FROM THE SQUID L. PEALEI
Descriptor: SEC1
Authors:Bracher, A, Weissenhorn, W.
Deposit date:2000-09-19
Release date:2001-01-31
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of neuronal squid Sec1 implicate inter-domain hinge movement in the release of t-SNAREs.
J.Mol.Biol., 306, 2001
1I96
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BU of 1i96 by Molmil
CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE TRANSLATION INITIATION FACTOR IF3 (C-TERMINAL DOMAIN)
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
1I95
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BU of 1i95 by Molmil
CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH EDEINE
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
4FCB
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BU of 4fcb by Molmil
Potent and Selective Phosphodiesterase 10A Inhibitors
Descriptor: 3,4-dimethyl-1-propyl-7-(quinolin-2-ylmethoxy)imidazo[1,5-a]quinoxaline, MAGNESIUM ION, ZINC ION, ...
Authors:Parris, K.D.
Deposit date:2012-05-24
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel triazines as potent and selective phosphodiesterase 10A inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4FCD
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BU of 4fcd by Molmil
Potent and Selective Phosphodiesterase 10A Inhibitors
Descriptor: 1-(2-chlorophenyl)-6,8-dimethoxy-3-methylimidazo[5,1-c][1,2,4]benzotriazine, MAGNESIUM ION, ZINC ION, ...
Authors:Parris, K.D.
Deposit date:2012-05-24
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Novel triazines as potent and selective phosphodiesterase 10A inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
7PO7
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BU of 7po7 by Molmil
Phosphoglycolate phosphatase from Mus musculus
Descriptor: ACETATE ION, CALCIUM ION, GLYCEROL, ...
Authors:Schloetzer, J, Schindelin, H, Fratz, S.
Deposit date:2021-09-08
Release date:2022-12-21
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Glycolytic flux control by drugging phosphoglycolate phosphatase.
Nat Commun, 13, 2022
7POE
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BU of 7poe by Molmil
Phosphoglycolate Phosphatase with Inhibitor CP1
Descriptor: 2-[[4-[4-[(2-carboxyphenyl)carbamoyl]phenoxy]phenyl]carbonylamino]benzoic acid, GLYCEROL, Glycerol-3-phosphate phosphatase, ...
Authors:Schloetzer, J, Fratz, S, Schindelin, H.
Deposit date:2021-09-08
Release date:2022-12-21
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Glycolytic flux control by drugging phosphoglycolate phosphatase.
Nat Commun, 13, 2022
6YV8
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BU of 6yv8 by Molmil
Mannosyltransferase PcManGT from Pyrobaculum calidifontis in complex with GDP and Mn2+
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Glycosyl transferase, family 2, ...
Authors:Divne, C, Gandini, R.
Deposit date:2020-04-28
Release date:2020-07-22
Last modified:2020-08-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold.
J.Mol.Biol., 432, 2020
6YV9
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BU of 6yv9 by Molmil
Mannosyltransferase PcManGT from Pyrobaculum calidifontis in complex with GDP-Man and Mn2+
Descriptor: GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, Glycosyl transferase, family 2, ...
Authors:Divne, C, Gandini, R.
Deposit date:2020-04-28
Release date:2020-07-22
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold.
J.Mol.Biol., 432, 2020
6YV7
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BU of 6yv7 by Molmil
Mannosyltransferase PcManGT from Pyrobaculum calidifontis
Descriptor: Glycosyl transferase, family 2
Authors:Divne, C, Rosaria, G.
Deposit date:2020-04-28
Release date:2020-07-22
Last modified:2020-08-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold.
J.Mol.Biol., 432, 2020
5ZZD
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BU of 5zzd by Molmil
Crystal structure of a protein from Aspergillus flavus
Descriptor: O-methyltransferase lepI, S-ADENOSYLMETHIONINE
Authors:Chang, Z.Y, Liu, W.D, Chen, C.C, Guo, R.T.
Deposit date:2018-05-31
Release date:2019-06-05
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of LepI, a multifunctional SAM-dependent enzyme which catalyzes pericyclic reactions in leporin biosynthesis.
Org.Biomol.Chem., 17, 2019
8OMV
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BU of 8omv by Molmil
Crystal structure of the constitutively active S117E/S181E mutant of human IKK2
Descriptor: Inhibitor of nuclear factor kappa-B kinase subunit beta
Authors:McEwen, A.G, Li, C, Moro, S, Poussin-Courmontagne, P, Zanier, K.
Deposit date:2023-03-31
Release date:2024-04-10
Method:X-RAY DIFFRACTION (4.16 Å)
Cite:A novel YDD(phi)X(phi) linear motif mediates docking of IKK catalytic dimers to NF-kappaB substrates: structural and functional insights
To be published
5QU8
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BU of 5qu8 by Molmil
Crystal Structure of symmetric swapped human Nck SH3.1 domain, 0.93A, orthorhombic form IV
Descriptor: Cytoplasmic protein NCK1, SODIUM ION
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (0.93 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU3
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BU of 5qu3 by Molmil
Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QUA
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BU of 5qua by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU1
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BU of 5qu1 by Molmil
Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A
Descriptor: Cytoplasmic protein NCK1, SULFATE ION
Authors:Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU5
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BU of 5qu5 by Molmil
Domain Swap in the first SH3 domain of human Nck1
Descriptor: Cytoplasmic protein NCK1
Authors:Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU2
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BU of 5qu2 by Molmil
Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY
Descriptor: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU7
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BU of 5qu7 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU4
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BU of 5qu4 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU6
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BU of 5qu6 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic
Descriptor: Cytoplasmic protein NCK1
Authors:Rudolph, M.G.
Deposit date:2019-12-13
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.816 Å)
Cite:Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
1NJM
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BU of 1njm by Molmil
The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed with a tRNA acceptor stem mimic (ASM) and the antibiotic sparsomycin
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L16, GENERAL STRESS PROTEIN CTC, ...
Authors:Bashan, A, Agmon, I, Zarivatch, R, Schluenzen, F, Harms, J.M, Berisio, R, Bartels, H, Hansen, H.A, Yonath, A.
Deposit date:2003-01-02
Release date:2003-02-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis of the ribosomal machinery for Peptide bond formation, translocation, and nascent chain progression
Mol.Cell, 11, 2003
1NJP
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BU of 1njp by Molmil
The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed with a tRNA acceptor stem mimic (ASM)
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L16, GENERAL STRESS PROTEIN CTC, ...
Authors:Bashan, A, Agmon, I, Zarivatch, R, Schluenzen, F, Harms, J.M, Berisio, R, Bartels, H, Hansen, H.A, Yonath, A.
Deposit date:2003-01-02
Release date:2003-02-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of the ribosomal machinery for Peptide bond formation, translocation, and nascent chain progression
Mol.Cell, 11, 2003

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