HEADER    HYDROLASE                               26-FEB-14   4CRD              
TITLE     CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD              
TITLE    2 GENERATION AND STRUCTURE AIDED DRUG DESIGN                           
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: COAGULATION FACTOR XI;                                     
COMPND   3 CHAIN: A;                                                            
COMPND   4 FRAGMENT: CATALYTIC DOMAIN, RESIDUES 388-625;                        
COMPND   5 SYNONYM: FXI, PLASMA THROMBOPLASTIN ANTECEDENT, PTA, COAGULATION     
COMPND   6  FACTOR XIA LIGHT CHAIN;                                             
COMPND   7 EC: 3.4.21.27;                                                       
COMPND   8 ENGINEERED: YES;                                                     
COMPND   9 MUTATION: YES                                                        
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 EXPRESSION_SYSTEM: PICHIA PASTORIS;                                  
SOURCE   6 EXPRESSION_SYSTEM_TAXID: 4922                                        
KEYWDS    HYDROLASE                                                             
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    J.SANDMARK,L.OSTER,O.FJELLSTROM,S.AKKAYA,H.G.BEISEL,P.O.ERIKSSON,     
AUTHOR   2 K.ERIXON,D.GUSTAFSSON,U.JURVA,D.KANG,D.KARIS,W.KNECHT,V.NERME,       
AUTHOR   3 I.NILSSON,T.OLSSON,A.REDZIC,R.ROTH,A.TIGERSTROM                      
REVDAT   1   11-FEB-15 4CRD    0                                                
JRNL        AUTH   O.FJELLSTROM,S.AKKAYA,H.BEISEL,P.ERIKSSON,K.ERIXON,          
JRNL        AUTH 2 D.GUSTAFSSON,U.JURVA,D.KANG,D.KARIS,W.KNECHT,V.NERME,        
JRNL        AUTH 3 I.NILSSON,T.OLSSON,A.REDZIC,R.ROTH,J.SANDMARK,A.TIGERSTROM,  
JRNL        AUTH 4 L.OSTER                                                      
JRNL        TITL   CREATING NOVEL ACTIVATED FACTOR XI INHIBITORS THROUGH        
JRNL        TITL 2 FRAGMENT BASED LEAD GENERATION AND STRUCTURE AIDED DRUG      
JRNL        TITL 3 DESIGN.                                                      
JRNL        REF    PLOS ONE                      V.  10 13705 2015              
JRNL        REFN                   ISSN 1932-6203                               
JRNL        PMID   25629509                                                     
JRNL        DOI    10.1371/JOURNAL.PONE.0113705                                 
REMARK   2                                                                      
REMARK   2 RESOLUTION.    2.10 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : REFMAC 5.8.0049                                      
REMARK   3   AUTHORS     : MURSHUDOV,SKUBAK,LEBEDEV,PANNU,                      
REMARK   3                 STEINER,NICHOLLS,WINN,LONG,VAGIN                     
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : MAXIMUM LIKELIHOOD                            
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 2.10                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 85.38                          
REMARK   3   DATA CUTOFF            (SIGMA(F)) : NONE                           
REMARK   3   COMPLETENESS FOR RANGE        (%) : 97.05                          
REMARK   3   NUMBER OF REFLECTIONS             : 15814                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.19220                         
REMARK   3   R VALUE            (WORKING SET) : 0.19057                         
REMARK   3   FREE R VALUE                     : 0.22032                         
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 5.1                             
REMARK   3   FREE R VALUE TEST SET COUNT      : 857                             
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : 20                           
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 2.100                        
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 2.155                        
REMARK   3   REFLECTION IN BIN     (WORKING SET) : 1099                         
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : 91.14                        
REMARK   3   BIN R VALUE           (WORKING SET) : 0.258                        
REMARK   3   BIN FREE R VALUE SET COUNT          : 63                           
REMARK   3   BIN FREE R VALUE                    : 0.279                        
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 1875                                    
REMARK   3   NUCLEIC ACID ATOMS       : 0                                       
REMARK   3   HETEROGEN ATOMS          : 50                                      
REMARK   3   SOLVENT ATOMS            : 76                                      
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : NULL                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 41.817                         
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : 0.00                                                 
REMARK   3    B22 (A**2) : 0.00                                                 
REMARK   3    B33 (A**2) : 0.00                                                 
REMARK   3    B12 (A**2) : 0.00                                                 
REMARK   3    B13 (A**2) : 0.00                                                 
REMARK   3    B23 (A**2) : 0.00                                                 
REMARK   3                                                                      
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.                                 
REMARK   3   ESU BASED ON R VALUE                            (A): 0.208         
REMARK   3   ESU BASED ON FREE R VALUE                       (A): 0.169         
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A): NULL          
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): NULL          
REMARK   3                                                                      
REMARK   3  CORRELATION COEFFICIENTS.                                           
REMARK   3   CORRELATION COEFFICIENT FO-FC      : 0.959                         
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE : 0.945                         
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT      
REMARK   3   BOND LENGTHS REFINED ATOMS        (A):  1976 ; 0.010 ; 0.019       
REMARK   3   BOND LENGTHS OTHERS               (A):  1802 ; 0.000 ; 0.020       
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES):  2686 ; 1.391 ; 1.958       
REMARK   3   BOND ANGLES OTHERS          (DEGREES):  4148 ; 3.645 ; 3.000       
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):   237 ; 6.634 ; 5.000       
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):    87 ;35.402 ;23.793       
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):   328 ;13.773 ;15.000       
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):    12 ;16.867 ;15.000       
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):   283 ; 0.077 ; 0.200       
REMARK   3   GENERAL PLANES REFINED ATOMS      (A):  2267 ; 0.005 ; 0.020       
REMARK   3   GENERAL PLANES OTHERS             (A):   456 ; 0.006 ; 0.020       
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND OTHERS            (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT      
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2):   948 ; 2.301 ; 3.920       
REMARK   3   MAIN-CHAIN BOND OTHER ATOMS    (A**2):   947 ; 2.292 ; 3.916       
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2):  1185 ; 3.145 ; 5.868       
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):  1028 ; 2.997 ; 4.347       
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ANISOTROPIC THERMAL FACTOR RESTRAINTS.   COUNT   RMS    WEIGHT      
REMARK   3   RIGID-BOND RESTRAINTS          (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; FREE ATOMS         (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; BONDED ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS STATISTICS                                           
REMARK   3   NUMBER OF DIFFERENT NCS GROUPS : NULL                              
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : NULL                                       
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED : MASK                                                 
REMARK   3   PARAMETERS FOR MASK CALCULATION                                    
REMARK   3   VDW PROBE RADIUS   : 1.20                                          
REMARK   3   ION PROBE RADIUS   : 0.80                                          
REMARK   3   SHRINKAGE RADIUS   : 0.80                                          
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE          
REMARK   3   RIDING POSITIONS.                                                  
REMARK   4                                                                      
REMARK   4 4CRD COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 26-FEB-14.                  
REMARK 100 THE PDBE ID CODE IS EBI-59833.                                       
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 25-JUN-09                          
REMARK 200  TEMPERATURE           (KELVIN) : 100                                
REMARK 200  PH                             : 8.5                                
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : ESRF                               
REMARK 200  BEAMLINE                       : ID14-4                             
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.94                               
REMARK 200  MONOCHROMATOR                  : NULL                               
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : CCD                                
REMARK 200  DETECTOR MANUFACTURER          : ADSC                               
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : MOSFLM                             
REMARK 200  DATA SCALING SOFTWARE          : SCALA                              
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 17077                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 2.10                               
REMARK 200  RESOLUTION RANGE LOW       (A) : 50.00                              
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 2.0                                
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 99.5                               
REMARK 200  DATA REDUNDANCY                : 5.8                                
REMARK 200  R MERGE                    (I) : 0.08                               
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 11.40                              
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.10                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 2.15                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 100.0                              
REMARK 200  DATA REDUNDANCY IN SHELL       : 4.3                                
REMARK 200  R MERGE FOR SHELL          (I) : 0.51                               
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : 2.40                               
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MAD                          
REMARK 200 SOFTWARE USED: MOLREP                                                
REMARK 200 STARTING MODEL: NULL                                                 
REMARK 200                                                                      
REMARK 200 REMARK: NONE                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 54.88                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.73                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 2M AMMONIUM SULFATE, 0.1M                
REMARK 280  TRIS-CL PH 8.5, 0.2M NACL                                           
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: I 2 3                            
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,-Y,Z                                                 
REMARK 290       3555   -X,Y,-Z                                                 
REMARK 290       4555   X,-Y,-Z                                                 
REMARK 290       5555   Z,X,Y                                                   
REMARK 290       6555   Z,-X,-Y                                                 
REMARK 290       7555   -Z,-X,Y                                                 
REMARK 290       8555   -Z,X,-Y                                                 
REMARK 290       9555   Y,Z,X                                                   
REMARK 290      10555   -Y,Z,-X                                                 
REMARK 290      11555   Y,-Z,-X                                                 
REMARK 290      12555   -Y,-Z,X                                                 
REMARK 290      13555   X+1/2,Y+1/2,Z+1/2                                       
REMARK 290      14555   -X+1/2,-Y+1/2,Z+1/2                                     
REMARK 290      15555   -X+1/2,Y+1/2,-Z+1/2                                     
REMARK 290      16555   X+1/2,-Y+1/2,-Z+1/2                                     
REMARK 290      17555   Z+1/2,X+1/2,Y+1/2                                       
REMARK 290      18555   Z+1/2,-X+1/2,-Y+1/2                                     
REMARK 290      19555   -Z+1/2,-X+1/2,Y+1/2                                     
REMARK 290      20555   -Z+1/2,X+1/2,-Y+1/2                                     
REMARK 290      21555   Y+1/2,Z+1/2,X+1/2                                       
REMARK 290      22555   -Y+1/2,Z+1/2,-X+1/2                                     
REMARK 290      23555   Y+1/2,-Z+1/2,-X+1/2                                     
REMARK 290      24555   -Y+1/2,-Z+1/2,X+1/2                                     
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   3 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   3  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   4  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   4  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   5  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY2   5  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   5  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   6  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY2   6 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   6  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   7  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY2   7 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   7  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   8  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY2   8  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   8  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   9  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY2   9  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY3   9  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  10  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY2  10  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY3  10 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  11  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY2  11  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY3  11 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  12  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY2  12  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY3  12  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  13  1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY2  13  0.000000  1.000000  0.000000       60.26750            
REMARK 290   SMTRY3  13  0.000000  0.000000  1.000000       60.26750            
REMARK 290   SMTRY1  14 -1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY2  14  0.000000 -1.000000  0.000000       60.26750            
REMARK 290   SMTRY3  14  0.000000  0.000000  1.000000       60.26750            
REMARK 290   SMTRY1  15 -1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY2  15  0.000000  1.000000  0.000000       60.26750            
REMARK 290   SMTRY3  15  0.000000  0.000000 -1.000000       60.26750            
REMARK 290   SMTRY1  16  1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY2  16  0.000000 -1.000000  0.000000       60.26750            
REMARK 290   SMTRY3  16  0.000000  0.000000 -1.000000       60.26750            
REMARK 290   SMTRY1  17  0.000000  0.000000  1.000000       60.26750            
REMARK 290   SMTRY2  17  1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY3  17  0.000000  1.000000  0.000000       60.26750            
REMARK 290   SMTRY1  18  0.000000  0.000000  1.000000       60.26750            
REMARK 290   SMTRY2  18 -1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY3  18  0.000000 -1.000000  0.000000       60.26750            
REMARK 290   SMTRY1  19  0.000000  0.000000 -1.000000       60.26750            
REMARK 290   SMTRY2  19 -1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY3  19  0.000000  1.000000  0.000000       60.26750            
REMARK 290   SMTRY1  20  0.000000  0.000000 -1.000000       60.26750            
REMARK 290   SMTRY2  20  1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY3  20  0.000000 -1.000000  0.000000       60.26750            
REMARK 290   SMTRY1  21  0.000000  1.000000  0.000000       60.26750            
REMARK 290   SMTRY2  21  0.000000  0.000000  1.000000       60.26750            
REMARK 290   SMTRY3  21  1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY1  22  0.000000 -1.000000  0.000000       60.26750            
REMARK 290   SMTRY2  22  0.000000  0.000000  1.000000       60.26750            
REMARK 290   SMTRY3  22 -1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY1  23  0.000000  1.000000  0.000000       60.26750            
REMARK 290   SMTRY2  23  0.000000  0.000000 -1.000000       60.26750            
REMARK 290   SMTRY3  23 -1.000000  0.000000  0.000000       60.26750            
REMARK 290   SMTRY1  24  0.000000 -1.000000  0.000000       60.26750            
REMARK 290   SMTRY2  24  0.000000  0.000000 -1.000000       60.26750            
REMARK 290   SMTRY3  24  1.000000  0.000000  0.000000       60.26750            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: TRIMERIC                   
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 TOTAL BURIED SURFACE AREA: 3890 ANGSTROM**2                          
REMARK 350 SURFACE AREA OF THE COMPLEX: 31240 ANGSTROM**2                       
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -132.7 KCAL/MOL                       
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 350   BIOMT1   2  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT2   2  0.000000  0.000000  1.000000        0.00000            
REMARK 350   BIOMT3   2  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT1   3  0.000000  0.000000  1.000000        0.00000            
REMARK 350   BIOMT2   3  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT3   3  0.000000  1.000000  0.000000        0.00000            
REMARK 375                                                                      
REMARK 375 SPECIAL POSITION                                                     
REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS            
REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL          
REMARK 375 POSITIONS.                                                           
REMARK 375                                                                      
REMARK 375 ATOM RES CSSEQI                                                      
REMARK 375 O4   SO4 A1245   LIES ON A SPECIAL POSITION.                         
REMARK 375 S    SO4 A1245   LIES ON A SPECIAL POSITION.                         
REMARK 375 O4   SO4 A1247   LIES ON A SPECIAL POSITION.                         
REMARK 375 S    SO4 A1247   LIES ON A SPECIAL POSITION.                         
REMARK 465                                                                      
REMARK 465 MISSING RESIDUES                                                     
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE                       
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                
REMARK 465                                                                      
REMARK 465   M RES C SSSEQI                                                     
REMARK 465     ALA A   244                                                      
REMARK 465     VAL A   245                                                      
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS                                      
REMARK 500                                                                      
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES              
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE               
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN               
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                 
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)               
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999                        
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996                     
REMARK 500                                                                      
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION                     
REMARK 500    GLY A 128   C     ASP A 129   N       0.183                       
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ASP A 148     -147.55   -162.05                                   
REMARK 500    SER A 214      -65.63   -130.24                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 525                                                                      
REMARK 525 SOLVENT                                                              
REMARK 525                                                                      
REMARK 525 THE FOLLOWING SOLVENT MOLECULES LIE FARTHER THAN EXPECTED            
REMARK 525 FROM THE PROTEIN OR NUCLEIC ACID MOLECULE AND ARE                    
REMARK 525 ASSOCIATED WITH A SYMMETRY RELATED MOLECULE (M=MODEL                 
REMARK 525 NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE          
REMARK 525 NUMBER; I=INSERTION CODE): THESE HAVE BEEN REPOSITIONED              
REMARK 525 BY APPLYING THE SYMMETRY TRANSFORMATION INDICATED.                   
REMARK 525                                                                      
REMARK 525  M RES CSSEQI     ORIGINAL COORDINATES   SYMMETRY TRANS.    DIST.    
REMARK 525                    X       Y       Z                                 
REMARK 525    HOH W  50   -43.889 -31.552   6.011    022      444      2.80     
REMARK 525    HOH W  42   -18.091 -63.361 -11.168    019      445      2.57     
REMARK 700                                                                      
REMARK 700 SHEET                                                                
REMARK 700 DETERMINATION METHOD: DSSP                                           
REMARK 700 THE SHEETS PRESENTED AS "AB" IN EACH CHAIN ON SHEET RECORDS          
REMARK 700 BELOW IS ACTUALLY AN  6-STRANDED BARREL THIS IS REPRESENTED BY       
REMARK 700 A  7-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS              
REMARK 700 ARE IDENTICAL.                                                       
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE OTJ A1244                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A1245                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A1246                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A1247                 
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: 4CR5   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CR9   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRA   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRB   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRC   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRE   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRF   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRG   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
DBREF  4CRD A   16   245  UNP    P03951   FA11_HUMAN     388    625             
SEQADV 4CRD ALA A   75  UNP  P03951    SER   452 ENGINEERED MUTATION            
SEQADV 4CRD ALA A   78  UNP  P03951    LYS   455 ENGINEERED MUTATION            
SEQADV 4CRD ALA A  115  UNP  P03951    THR   493 ENGINEERED MUTATION            
SEQADV 4CRD SER A  123  UNP  P03951    CYS   500 ENGINEERED MUTATION            
SEQRES   1 A  238  ILE VAL GLY GLY THR ALA SER VAL ARG GLY GLU TRP PRO          
SEQRES   2 A  238  TRP GLN VAL THR LEU HIS THR THR SER PRO THR GLN ARG          
SEQRES   3 A  238  HIS LEU CYS GLY GLY SER ILE ILE GLY ASN GLN TRP ILE          
SEQRES   4 A  238  LEU THR ALA ALA HIS CYS PHE TYR GLY VAL GLU SER PRO          
SEQRES   5 A  238  LYS ILE LEU ARG VAL TYR SER GLY ILE LEU ASN GLN ALA          
SEQRES   6 A  238  GLU ILE ALA GLU ASP THR SER PHE PHE GLY VAL GLN GLU          
SEQRES   7 A  238  ILE ILE ILE HIS ASP GLN TYR LYS MET ALA GLU SER GLY          
SEQRES   8 A  238  TYR ASP ILE ALA LEU LEU LYS LEU GLU THR THR VAL ASN          
SEQRES   9 A  238  TYR ALA ASP SER GLN ARG PRO ILE SER LEU PRO SER LYS          
SEQRES  10 A  238  GLY ASP ARG ASN VAL ILE TYR THR ASP CYS TRP VAL THR          
SEQRES  11 A  238  GLY TRP GLY TYR ARG LYS LEU ARG ASP LYS ILE GLN ASN          
SEQRES  12 A  238  THR LEU GLN LYS ALA LYS ILE PRO LEU VAL THR ASN GLU          
SEQRES  13 A  238  GLU CYS GLN LYS ARG TYR ARG GLY HIS LYS ILE THR HIS          
SEQRES  14 A  238  LYS MET ILE CYS ALA GLY TYR ARG GLU GLY GLY LYS ASP          
SEQRES  15 A  238  ALA CYS LYS GLY ASP SER GLY GLY PRO LEU SER CYS LYS          
SEQRES  16 A  238  HIS ASN GLU VAL TRP HIS LEU VAL GLY ILE THR SER TRP          
SEQRES  17 A  238  GLY GLU GLY CYS ALA GLN ARG GLU ARG PRO GLY VAL TYR          
SEQRES  18 A  238  THR ASN VAL VAL GLU TYR VAL ASP TRP ILE LEU GLU LYS          
SEQRES  19 A  238  THR GLN ALA VAL                                              
HET    OTJ  A1244      35                                                       
HET    SO4  A1245       5                                                       
HET    SO4  A1246       5                                                       
HET    SO4  A1247       5                                                       
HETNAM     OTJ METHYL N-[4-[5-CHLORO-2-[[3-[5-CHLORO-2-                         
HETNAM   2 OTJ  (TETRAZOL-1-YL)PHENYL]PROPANOYLAMINO]METHYL]-1H-                
HETNAM   3 OTJ  IMIDAZOL-4-YL]PHENYL]CARBAMATE                                  
HETNAM     SO4 SULFATE ION                                                      
FORMUL   2  OTJ    C22 H22 CL2 N8 O3                                            
FORMUL   3  SO4    3(O4 S 2-)                                                   
FORMUL   4  HOH   *76(H2 O)                                                     
HELIX    1   1 ALA A   55  TYR A   59A 5                                   6    
HELIX    2   2 SER A   61  LYS A   63  5                                   3    
HELIX    3   3 GLN A   74  ILE A   77  5                                   4    
HELIX    4   4 MET A   96  GLY A  100  5                                   5    
HELIX    5   5 SER A  126  ARG A  130  5                                   5    
HELIX    6   6 THR A  164  TYR A  172  1                                   9    
HELIX    7   7 TYR A  234  THR A  242  1                                   9    
SHEET    1  AA 8 THR A  20  ALA A  21  0                                        
SHEET    2  AA 8 GLN A 156  LYS A 159 -1  O  LYS A 157   N  THR A  20           
SHEET    3  AA 8 CYS A 136  GLY A 140 -1  O  VAL A 138   N  ALA A 158           
SHEET    4  AA 8 PRO A 198  HIS A 202A-1  O  PRO A 198   N  THR A 139           
SHEET    5  AA 8 VAL A 202D TRP A 215 -1  O  VAL A 202D  N  HIS A 202A          
SHEET    6  AA 8 GLY A 226  ASN A 230 -1  O  VAL A 227   N  TRP A 215           
SHEET    7  AA 8 MET A 180  ALA A 183 -1  O  ILE A 181   N  TYR A 228           
SHEET    8  AA 8 LEU A 162  VAL A 163 -1  O  VAL A 163   N  CYS A 182           
SHEET    1  AB 7 GLN A  30  THR A  35  0                                        
SHEET    2  AB 7 ARG A  37D GLY A  46 -1  O  ARG A  37D  N  THR A  35           
SHEET    3  AB 7 TRP A  51  THR A  54 -1  O  TRP A  51   N  ILE A  45           
SHEET    4  AB 7 ALA A 104  LEU A 108 -1  O  ALA A 104   N  THR A  54           
SHEET    5  AB 7 PHE A  83  ILE A  90 -1  N  GLN A  86   O  LYS A 107           
SHEET    6  AB 7 LEU A  65  TYR A  68 -1  O  LEU A  65   N  VAL A  85           
SHEET    7  AB 7 GLN A  30  THR A  35 -1  O  THR A  32   N  TYR A  68           
SSBOND   1 CYS A   40    CYS A   58                          1555   1555  2.02  
SSBOND   2 CYS A   40    CYS A   58                          1555   1555  2.08  
SSBOND   3 CYS A  136    CYS A  201                          1555   1555  2.05  
SSBOND   4 CYS A  168    CYS A  182                          1555   1555  2.04  
SSBOND   5 CYS A  191    CYS A  219                          1555   1555  2.07  
CISPEP   1 SER A   37    PRO A   37A         0        -5.25                     
SITE     1 AC1 21 ARG A  37D HIS A  38  LEU A  39  ASN A 113                    
SITE     2 AC1 21 ILE A 151  ASP A 189  CYS A 191  LYS A 192                    
SITE     3 AC1 21 GLY A 193  ASP A 194  SER A 195  SER A 214                    
SITE     4 AC1 21 TRP A 215  GLY A 216  GLY A 218  CYS A 219                    
SITE     5 AC1 21 GLY A 226  VAL A 227  TYR A 228  HOH A2013                    
SITE     6 AC1 21 HOH A2057                                                     
SITE     1 AC2  2 LYS A 127  ARG A 130                                          
SITE     1 AC3  3 TYR A 184A ARG A 185  GLU A 186                               
SITE     1 AC4  1 ASN A 131                                                     
CRYST1  120.535  120.535  120.535  90.00  90.00  90.00 I 2 3        24          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.008296  0.000000  0.000000        0.00000                         
SCALE2      0.000000  0.008296  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.008296        0.00000                         
ATOM      1  N   ILE A  16     -21.738 -48.538  -1.952  1.00 32.61           N  
ATOM      2  CA  ILE A  16     -20.747 -47.426  -1.954  1.00 32.76           C  
ATOM      3  C   ILE A  16     -19.516 -47.966  -1.270  1.00 31.90           C  
ATOM      4  O   ILE A  16     -19.628 -48.534  -0.205  1.00 31.82           O  
ATOM      5  CB  ILE A  16     -21.260 -46.203  -1.172  1.00 31.57           C  
ATOM      6  CG1 ILE A  16     -22.544 -45.662  -1.801  1.00 31.27           C  
ATOM      7  CG2 ILE A  16     -20.184 -45.132  -1.049  1.00 31.36           C  
ATOM      8  CD1 ILE A  16     -22.389 -44.949  -3.115  1.00 33.72           C  
ATOM      9  N   VAL A  17     -18.356 -47.850  -1.909  1.00 33.88           N  
ATOM     10  CA  VAL A  17     -17.102 -48.287  -1.291  1.00 33.03           C  
ATOM     11  C   VAL A  17     -16.484 -47.100  -0.560  1.00 33.57           C  
ATOM     12  O   VAL A  17     -16.491 -45.981  -1.062  1.00 34.20           O  
ATOM     13  CB  VAL A  17     -16.078 -48.828  -2.323  1.00 33.78           C  
ATOM     14  CG1 VAL A  17     -14.829 -49.387  -1.635  1.00 32.66           C  
ATOM     15  CG2 VAL A  17     -16.708 -49.907  -3.195  1.00 34.98           C  
ATOM     16  N   GLY A  18     -15.956 -47.362   0.635  1.00 37.20           N  
ATOM     17  CA  GLY A  18     -15.267 -46.349   1.426  1.00 36.14           C  
ATOM     18  C   GLY A  18     -16.108 -45.175   1.891  1.00 38.92           C  
ATOM     19  O   GLY A  18     -15.583 -44.079   2.123  1.00 37.37           O  
ATOM     20  N   GLY A  19     -17.412 -45.389   2.034  1.00 37.60           N  
ATOM     21  CA  GLY A  19     -18.322 -44.297   2.432  1.00 37.65           C  
ATOM     22  C   GLY A  19     -18.712 -44.400   3.890  1.00 39.45           C  
ATOM     23  O   GLY A  19     -18.186 -45.225   4.608  1.00 35.67           O  
ATOM     24  N   THR A  20     -19.656 -43.571   4.324  1.00 43.66           N  
ATOM     25  CA  THR A  20     -20.178 -43.651   5.679  1.00 43.43           C  
ATOM     26  C   THR A  20     -21.703 -43.576   5.636  1.00 41.71           C  
ATOM     27  O   THR A  20     -22.275 -43.121   4.651  1.00 38.14           O  
ATOM     28  CB  THR A  20     -19.665 -42.483   6.550  1.00 44.25           C  
ATOM     29  OG1 THR A  20     -19.999 -41.241   5.924  1.00 50.09           O  
ATOM     30  CG2 THR A  20     -18.173 -42.557   6.752  1.00 45.97           C  
ATOM     31  N   ALA A  21     -22.334 -44.001   6.729  1.00 41.52           N  
ATOM     32  CA  ALA A  21     -23.777 -43.882   6.934  1.00 41.51           C  
ATOM     33  C   ALA A  21     -24.258 -42.465   6.752  1.00 41.71           C  
ATOM     34  O   ALA A  21     -23.656 -41.519   7.266  1.00 42.51           O  
ATOM     35  CB  ALA A  21     -24.137 -44.354   8.335  1.00 44.27           C  
ATOM     36  N   SER A  22     -25.361 -42.295   6.048  1.00 41.58           N  
ATOM     37  CA  SER A  22     -25.942 -40.964   5.913  1.00 41.64           C  
ATOM     38  C   SER A  22     -26.800 -40.607   7.133  1.00 41.82           C  
ATOM     39  O   SER A  22     -27.260 -41.480   7.845  1.00 37.97           O  
ATOM     40  CB  SER A  22     -26.769 -40.872   4.649  1.00 42.89           C  
ATOM     41  OG  SER A  22     -25.938 -41.045   3.515  1.00 44.68           O  
ATOM     42  N   VAL A  23     -26.980 -39.315   7.359  1.00 44.52           N  
ATOM     43  CA  VAL A  23     -27.942 -38.818   8.352  1.00 45.89           C  
ATOM     44  C   VAL A  23     -29.300 -38.927   7.720  1.00 44.97           C  
ATOM     45  O   VAL A  23     -29.444 -38.639   6.543  1.00 43.78           O  
ATOM     46  CB  VAL A  23     -27.683 -37.342   8.697  1.00 46.56           C  
ATOM     47  CG1 VAL A  23     -28.757 -36.800   9.632  1.00 47.16           C  
ATOM     48  CG2 VAL A  23     -26.295 -37.164   9.312  1.00 47.38           C  
ATOM     49  N   ARG A  24     -30.305 -39.331   8.488  1.00 47.59           N  
ATOM     50  CA  ARG A  24     -31.646 -39.414   7.948  1.00 44.42           C  
ATOM     51  C   ARG A  24     -32.018 -38.110   7.234  1.00 46.41           C  
ATOM     52  O   ARG A  24     -31.912 -37.019   7.793  1.00 46.80           O  
ATOM     53  CB  ARG A  24     -32.663 -39.724   9.036  1.00 45.41           C  
ATOM     54  CG  ARG A  24     -34.052 -39.984   8.485  1.00 47.04           C  
ATOM     55  CD  ARG A  24     -35.004 -40.463   9.572  1.00 46.62           C  
ATOM     56  NE  ARG A  24     -34.650 -41.785  10.071  1.00 47.80           N  
ATOM     57  CZ  ARG A  24     -35.046 -42.936   9.528  1.00 43.99           C  
ATOM     58  NH1 ARG A  24     -35.808 -42.940   8.433  1.00 41.23           N  
ATOM     59  NH2 ARG A  24     -34.663 -44.085  10.072  1.00 45.34           N  
ATOM     60  N   GLY A  25     -32.423 -38.234   5.978  1.00 44.25           N  
ATOM     61  CA  GLY A  25     -32.910 -37.099   5.210  1.00 43.56           C  
ATOM     62  C   GLY A  25     -31.918 -36.089   4.666  1.00 40.63           C  
ATOM     63  O   GLY A  25     -32.332 -35.102   4.083  1.00 43.98           O  
ATOM     64  N   GLU A  26     -30.622 -36.317   4.819  1.00 38.61           N  
ATOM     65  CA  GLU A  26     -29.673 -35.428   4.156  1.00 42.30           C  
ATOM     66  C   GLU A  26     -29.656 -35.596   2.633  1.00 40.03           C  
ATOM     67  O   GLU A  26     -29.174 -34.724   1.951  1.00 38.61           O  
ATOM     68  CB  GLU A  26     -28.257 -35.526   4.754  1.00 45.35           C  
ATOM     69  CG  GLU A  26     -27.455 -36.751   4.413  1.00 46.86           C  
ATOM     70  CD  GLU A  26     -26.041 -36.681   4.959  1.00 46.35           C  
ATOM     71  OE1 GLU A  26     -25.309 -35.716   4.649  1.00 50.03           O  
ATOM     72  OE2 GLU A  26     -25.654 -37.602   5.699  1.00 45.94           O  
ATOM     73  N   TRP A  27     -30.209 -36.694   2.109  1.00 37.25           N  
ATOM     74  CA  TRP A  27     -30.339 -36.879   0.662  1.00 35.58           C  
ATOM     75  C   TRP A  27     -31.791 -37.173   0.335  1.00 38.45           C  
ATOM     76  O   TRP A  27     -32.129 -38.316  -0.077  1.00 35.30           O  
ATOM     77  CB  TRP A  27     -29.453 -38.050   0.197  1.00 34.16           C  
ATOM     78  CG  TRP A  27     -28.074 -37.975   0.685  1.00 34.31           C  
ATOM     79  CD1 TRP A  27     -27.477 -38.809   1.585  1.00 35.77           C  
ATOM     80  CD2 TRP A  27     -27.085 -37.007   0.319  1.00 35.29           C  
ATOM     81  NE1 TRP A  27     -26.181 -38.426   1.801  1.00 34.83           N  
ATOM     82  CE2 TRP A  27     -25.908 -37.327   1.026  1.00 35.88           C  
ATOM     83  CE3 TRP A  27     -27.072 -35.920  -0.564  1.00 38.59           C  
ATOM     84  CZ2 TRP A  27     -24.740 -36.579   0.909  1.00 36.47           C  
ATOM     85  CZ3 TRP A  27     -25.900 -35.183  -0.701  1.00 37.95           C  
ATOM     86  CH2 TRP A  27     -24.755 -35.511   0.037  1.00 38.54           C  
ATOM     87  N   PRO A  28     -32.671 -36.159   0.513  1.00 39.40           N  
ATOM     88  CA  PRO A  28     -34.113 -36.375   0.407  1.00 38.16           C  
ATOM     89  C   PRO A  28     -34.663 -36.607  -1.014  1.00 34.94           C  
ATOM     90  O   PRO A  28     -35.849 -36.896  -1.174  1.00 36.04           O  
ATOM     91  CB  PRO A  28     -34.691 -35.078   1.007  1.00 39.42           C  
ATOM     92  CG  PRO A  28     -33.662 -34.029   0.677  1.00 40.02           C  
ATOM     93  CD  PRO A  28     -32.355 -34.749   0.846  1.00 39.77           C  
ATOM     94  N   TRP A  29     -33.840 -36.422  -2.038  1.00 35.94           N  
ATOM     95  CA  TRP A  29     -34.240 -36.765  -3.421  1.00 35.37           C  
ATOM     96  C   TRP A  29     -33.907 -38.232  -3.755  1.00 35.62           C  
ATOM     97  O   TRP A  29     -34.369 -38.752  -4.769  1.00 36.56           O  
ATOM     98  CB  TRP A  29     -33.552 -35.858  -4.446  1.00 34.64           C  
ATOM     99  CG  TRP A  29     -32.076 -35.720  -4.217  1.00 37.87           C  
ATOM    100  CD1 TRP A  29     -31.065 -36.471  -4.779  1.00 39.21           C  
ATOM    101  CD2 TRP A  29     -31.439 -34.776  -3.354  1.00 40.40           C  
ATOM    102  NE1 TRP A  29     -29.841 -36.037  -4.308  1.00 39.89           N  
ATOM    103  CE2 TRP A  29     -30.048 -35.008  -3.424  1.00 39.97           C  
ATOM    104  CE3 TRP A  29     -31.913 -33.756  -2.518  1.00 41.94           C  
ATOM    105  CZ2 TRP A  29     -29.131 -34.242  -2.710  1.00 40.87           C  
ATOM    106  CZ3 TRP A  29     -30.990 -33.006  -1.797  1.00 39.78           C  
ATOM    107  CH2 TRP A  29     -29.619 -33.255  -1.899  1.00 40.98           C  
ATOM    108  N   GLN A  30     -33.077 -38.873  -2.932  1.00 36.32           N  
ATOM    109  CA  GLN A  30     -32.652 -40.274  -3.170  1.00 33.91           C  
ATOM    110  C   GLN A  30     -33.814 -41.224  -2.911  1.00 35.33           C  
ATOM    111  O   GLN A  30     -34.430 -41.163  -1.851  1.00 30.03           O  
ATOM    112  CB  GLN A  30     -31.495 -40.649  -2.246  1.00 33.87           C  
ATOM    113  CG  GLN A  30     -31.134 -42.140  -2.194  1.00 34.15           C  
ATOM    114  CD  GLN A  30     -30.135 -42.579  -3.259  1.00 35.08           C  
ATOM    115  OE1 GLN A  30     -28.997 -42.102  -3.301  1.00 31.57           O  
ATOM    116  NE2 GLN A  30     -30.550 -43.531  -4.110  1.00 36.46           N  
ATOM    117  N   VAL A  31     -34.118 -42.090  -3.879  1.00 33.59           N  
ATOM    118  CA  VAL A  31     -35.073 -43.173  -3.648  1.00 33.53           C  
ATOM    119  C   VAL A  31     -34.409 -44.546  -3.800  1.00 32.84           C  
ATOM    120  O   VAL A  31     -33.296 -44.639  -4.353  1.00 30.24           O  
ATOM    121  CB  VAL A  31     -36.320 -43.081  -4.564  1.00 33.05           C  
ATOM    122  CG1 VAL A  31     -37.069 -41.773  -4.322  1.00 33.23           C  
ATOM    123  CG2 VAL A  31     -35.988 -43.256  -6.054  1.00 34.41           C  
ATOM    124  N   THR A  32     -35.082 -45.576  -3.271  1.00 30.01           N  
ATOM    125  CA  THR A  32     -34.747 -46.990  -3.537  1.00 32.53           C  
ATOM    126  C   THR A  32     -35.884 -47.548  -4.364  1.00 35.76           C  
ATOM    127  O   THR A  32     -37.066 -47.473  -3.984  1.00 35.73           O  
ATOM    128  CB  THR A  32     -34.550 -47.832  -2.260  1.00 34.19           C  
ATOM    129  OG1 THR A  32     -34.335 -49.205  -2.599  1.00 36.22           O  
ATOM    130  CG2 THR A  32     -35.738 -47.779  -1.334  1.00 34.98           C  
ATOM    131  N   LEU A  33     -35.522 -48.051  -5.525  1.00 35.31           N  
ATOM    132  CA  LEU A  33     -36.452 -48.703  -6.438  1.00 35.06           C  
ATOM    133  C   LEU A  33     -36.364 -50.211  -6.139  1.00 35.57           C  
ATOM    134  O   LEU A  33     -35.275 -50.772  -6.139  1.00 32.99           O  
ATOM    135  CB  LEU A  33     -36.009 -48.416  -7.870  1.00 38.34           C  
ATOM    136  CG  LEU A  33     -36.947 -48.517  -9.080  1.00 43.67           C  
ATOM    137  CD1 LEU A  33     -36.289 -49.331 -10.181  1.00 44.74           C  
ATOM    138  CD2 LEU A  33     -38.318 -49.111  -8.777  1.00 47.20           C  
ATOM    139  N   HIS A  34     -37.500 -50.839  -5.852  1.00 34.54           N  
ATOM    140  CA  HIS A  34     -37.596 -52.276  -5.624  1.00 32.28           C  
ATOM    141  C   HIS A  34     -38.353 -52.955  -6.768  1.00 32.92           C  
ATOM    142  O   HIS A  34     -39.163 -52.325  -7.490  1.00 32.32           O  
ATOM    143  CB  HIS A  34     -38.321 -52.615  -4.290  1.00 32.03           C  
ATOM    144  CG  HIS A  34     -37.480 -52.437  -3.066  1.00 31.33           C  
ATOM    145  ND1 HIS A  34     -37.563 -53.269  -1.973  1.00 34.14           N  
ATOM    146  CD2 HIS A  34     -36.565 -51.495  -2.747  1.00 34.10           C  
ATOM    147  CE1 HIS A  34     -36.709 -52.874  -1.046  1.00 33.86           C  
ATOM    148  NE2 HIS A  34     -36.085 -51.801  -1.497  1.00 33.54           N  
ATOM    149  N   THR A  35     -38.072 -54.257  -6.918  1.00 32.47           N  
ATOM    150  CA  THR A  35     -38.870 -55.164  -7.737  1.00 33.81           C  
ATOM    151  C   THR A  35     -39.562 -56.175  -6.820  1.00 37.97           C  
ATOM    152  O   THR A  35     -38.975 -56.596  -5.840  1.00 39.72           O  
ATOM    153  CB  THR A  35     -38.024 -55.940  -8.762  1.00 36.68           C  
ATOM    154  OG1 THR A  35     -38.875 -56.863  -9.453  1.00 37.79           O  
ATOM    155  CG2 THR A  35     -36.883 -56.718  -8.076  1.00 34.35           C  
ATOM    156  N   THR A  36     -40.798 -56.580  -7.134  1.00 40.66           N  
ATOM    157  CA  THR A  36     -41.507 -57.542  -6.279  1.00 42.02           C  
ATOM    158  C   THR A  36     -41.319 -58.993  -6.753  1.00 44.63           C  
ATOM    159  O   THR A  36     -41.722 -59.933  -6.076  1.00 47.86           O  
ATOM    160  CB  THR A  36     -43.015 -57.255  -6.225  1.00 43.76           C  
ATOM    161  OG1 THR A  36     -43.542 -57.253  -7.560  1.00 42.60           O  
ATOM    162  CG2 THR A  36     -43.287 -55.930  -5.544  1.00 44.23           C  
ATOM    163  N   SER A  37     -40.719 -59.156  -7.920  1.00 42.67           N  
ATOM    164  CA  SER A  37     -40.511 -60.450  -8.531  1.00 46.78           C  
ATOM    165  C   SER A  37     -39.051 -60.910  -8.335  1.00 45.68           C  
ATOM    166  O   SER A  37     -38.132 -60.130  -8.556  1.00 47.35           O  
ATOM    167  CB  SER A  37     -40.858 -60.328 -10.021  1.00 46.38           C  
ATOM    168  OG  SER A  37     -40.312 -61.402 -10.743  1.00 50.93           O  
ATOM    169  N   PRO A  37A    -38.815 -62.169  -7.901  1.00 43.55           N  
ATOM    170  CA  PRO A  37A    -39.731 -63.207  -7.467  1.00 42.81           C  
ATOM    171  C   PRO A  37A    -40.175 -62.991  -6.020  1.00 44.54           C  
ATOM    172  O   PRO A  37A    -41.329 -63.277  -5.718  1.00 41.23           O  
ATOM    173  CB  PRO A  37A    -38.899 -64.496  -7.567  1.00 42.90           C  
ATOM    174  CG  PRO A  37A    -37.476 -64.059  -7.430  1.00 42.08           C  
ATOM    175  CD  PRO A  37A    -37.435 -62.679  -8.049  1.00 42.47           C  
ATOM    176  N   THR A  37B    -39.253 -62.584  -5.135  1.00 38.01           N  
ATOM    177  CA  THR A  37B    -39.617 -61.979  -3.831  1.00 41.51           C  
ATOM    178  C   THR A  37B    -39.048 -60.547  -3.839  1.00 42.81           C  
ATOM    179  O   THR A  37B    -38.145 -60.226  -4.615  1.00 39.96           O  
ATOM    180  CB  THR A  37B    -39.155 -62.766  -2.568  1.00 39.88           C  
ATOM    181  OG1 THR A  37B    -37.743 -62.974  -2.569  1.00 37.90           O  
ATOM    182  CG2 THR A  37B    -39.844 -64.118  -2.465  1.00 41.86           C  
ATOM    183  N   GLN A  37C    -39.614 -59.672  -3.017  1.00 39.98           N  
ATOM    184  CA  GLN A  37C    -39.275 -58.255  -3.124  1.00 40.98           C  
ATOM    185  C   GLN A  37C    -37.813 -57.972  -2.761  1.00 36.62           C  
ATOM    186  O   GLN A  37C    -37.361 -58.423  -1.749  1.00 36.80           O  
ATOM    187  CB  GLN A  37C    -40.207 -57.412  -2.258  1.00 40.23           C  
ATOM    188  CG  GLN A  37C    -39.831 -55.935  -2.250  1.00 40.86           C  
ATOM    189  CD  GLN A  37C    -40.908 -55.037  -1.652  1.00 42.42           C  
ATOM    190  OE1 GLN A  37C    -40.605 -53.960  -1.148  1.00 40.98           O  
ATOM    191  NE2 GLN A  37C    -42.175 -55.471  -1.716  1.00 42.79           N  
ATOM    192  N   ARG A  37D    -37.110 -57.189  -3.585  1.00 36.90           N  
ATOM    193  CA  ARG A  37D    -35.745 -56.734  -3.260  1.00 39.65           C  
ATOM    194  C   ARG A  37D    -35.400 -55.373  -3.879  1.00 37.17           C  
ATOM    195  O   ARG A  37D    -35.955 -54.993  -4.911  1.00 31.89           O  
ATOM    196  CB  ARG A  37D    -34.714 -57.763  -3.759  1.00 43.09           C  
ATOM    197  CG  ARG A  37D    -34.901 -58.122  -5.230  1.00 48.58           C  
ATOM    198  CD  ARG A  37D    -33.652 -58.698  -5.894  1.00 56.63           C  
ATOM    199  NE  ARG A  37D    -33.788 -58.710  -7.360  1.00 59.53           N  
ATOM    200  CZ  ARG A  37D    -33.187 -57.868  -8.224  1.00 67.73           C  
ATOM    201  NH1 ARG A  37D    -32.354 -56.905  -7.807  1.00 59.98           N  
ATOM    202  NH2 ARG A  37D    -33.422 -57.995  -9.539  1.00 63.23           N  
ATOM    203  N   HIS A  38     -34.436 -54.680  -3.270  1.00 35.20           N  
ATOM    204  CA  HIS A  38     -33.829 -53.491  -3.871  1.00 33.72           C  
ATOM    205  C   HIS A  38     -33.286 -53.829  -5.265  1.00 35.32           C  
ATOM    206  O   HIS A  38     -32.645 -54.865  -5.449  1.00 32.70           O  
ATOM    207  CB  HIS A  38     -32.704 -52.937  -2.978  1.00 32.46           C  
ATOM    208  CG  HIS A  38     -31.889 -51.853  -3.619  1.00 31.77           C  
ATOM    209  ND1 HIS A  38     -32.204 -50.513  -3.507  1.00 31.05           N  
ATOM    210  CD2 HIS A  38     -30.758 -51.912  -4.370  1.00 31.83           C  
ATOM    211  CE1 HIS A  38     -31.310 -49.795  -4.165  1.00 32.62           C  
ATOM    212  NE2 HIS A  38     -30.416 -50.617  -4.693  1.00 32.87           N  
ATOM    213  N   LEU A  39     -33.561 -52.933  -6.223  1.00 33.85           N  
ATOM    214  CA  LEU A  39     -33.110 -53.046  -7.609  1.00 33.24           C  
ATOM    215  C   LEU A  39     -32.088 -51.983  -8.001  1.00 32.83           C  
ATOM    216  O   LEU A  39     -31.034 -52.308  -8.566  1.00 30.55           O  
ATOM    217  CB  LEU A  39     -34.297 -52.920  -8.559  1.00 33.37           C  
ATOM    218  CG  LEU A  39     -33.995 -53.038 -10.057  1.00 36.20           C  
ATOM    219  CD1 LEU A  39     -33.358 -54.370 -10.404  1.00 36.71           C  
ATOM    220  CD2 LEU A  39     -35.268 -52.865 -10.862  1.00 37.51           C  
ATOM    221  N  BCYS A  40     -32.390 -50.728  -7.671  0.38 30.61           N  
ATOM    222  CA BCYS A  40     -31.599 -49.592  -8.116  0.38 29.60           C  
ATOM    223  C  BCYS A  40     -31.853 -48.338  -7.272  0.38 30.67           C  
ATOM    224  O  BCYS A  40     -32.810 -48.289  -6.495  0.38 29.33           O  
ATOM    225  CB BCYS A  40     -31.944 -49.291  -9.568  0.38 30.11           C  
ATOM    226  SG BCYS A  40     -31.010 -50.257 -10.788  0.38 30.43           S  
ATOM    227  N  CCYS A  40     -32.419 -50.714  -7.772  0.62 31.62           N  
ATOM    228  CA CCYS A  40     -31.449 -49.650  -7.954  0.62 31.33           C  
ATOM    229  C  CCYS A  40     -31.893 -48.303  -7.368  0.62 32.39           C  
ATOM    230  O  CCYS A  40     -33.021 -48.145  -6.876  0.62 30.34           O  
ATOM    231  CB CCYS A  40     -31.014 -49.522  -9.426  0.62 34.81           C  
ATOM    232  SG CCYS A  40     -32.091 -48.692 -10.616  0.62 38.66           S  
ATOM    233  N   GLY A  41     -30.980 -47.339  -7.420  1.00 30.78           N  
ATOM    234  CA  GLY A  41     -31.233 -45.990  -6.875  1.00 31.63           C  
ATOM    235  C   GLY A  41     -32.014 -45.166  -7.881  1.00 31.34           C  
ATOM    236  O   GLY A  41     -32.260 -45.601  -9.020  1.00 32.17           O  
ATOM    237  N   GLY A  42     -32.455 -43.995  -7.442  1.00 31.05           N  
ATOM    238  CA  GLY A  42     -33.061 -43.018  -8.325  1.00 29.93           C  
ATOM    239  C   GLY A  42     -33.163 -41.674  -7.630  1.00 31.91           C  
ATOM    240  O   GLY A  42     -32.890 -41.566  -6.420  1.00 29.44           O  
ATOM    241  N   SER A  43     -33.572 -40.655  -8.377  1.00 31.50           N  
ATOM    242  CA  SER A  43     -33.714 -39.323  -7.819  1.00 33.25           C  
ATOM    243  C   SER A  43     -35.049 -38.704  -8.137  1.00 33.10           C  
ATOM    244  O   SER A  43     -35.495 -38.760  -9.271  1.00 34.29           O  
ATOM    245  CB  SER A  43     -32.619 -38.417  -8.358  1.00 32.49           C  
ATOM    246  OG  SER A  43     -31.356 -38.959  -8.040  1.00 31.07           O  
ATOM    247  N   ILE A  44     -35.662 -38.073  -7.144  1.00 33.46           N  
ATOM    248  CA  ILE A  44     -36.907 -37.300  -7.379  1.00 33.01           C  
ATOM    249  C   ILE A  44     -36.538 -36.017  -8.129  1.00 32.56           C  
ATOM    250  O   ILE A  44     -35.692 -35.245  -7.656  1.00 33.79           O  
ATOM    251  CB  ILE A  44     -37.628 -36.954  -6.050  1.00 32.13           C  
ATOM    252  CG1 ILE A  44     -38.048 -38.228  -5.318  1.00 32.57           C  
ATOM    253  CG2 ILE A  44     -38.881 -36.117  -6.292  1.00 31.47           C  
ATOM    254  CD1 ILE A  44     -38.669 -37.974  -3.962  1.00 33.03           C  
ATOM    255  N   ILE A  45     -37.117 -35.809  -9.306  1.00 32.03           N  
ATOM    256  CA  ILE A  45     -36.893 -34.553 -10.020  1.00 35.95           C  
ATOM    257  C   ILE A  45     -38.174 -33.762 -10.256  1.00 36.09           C  
ATOM    258  O   ILE A  45     -38.116 -32.632 -10.665  1.00 37.39           O  
ATOM    259  CB  ILE A  45     -36.158 -34.747 -11.356  1.00 37.90           C  
ATOM    260  CG1 ILE A  45     -36.977 -35.611 -12.314  1.00 37.92           C  
ATOM    261  CG2 ILE A  45     -34.768 -35.338 -11.126  1.00 36.10           C  
ATOM    262  CD1 ILE A  45     -36.562 -35.435 -13.759  1.00 40.06           C  
ATOM    263  N   GLY A  46     -39.314 -34.361  -9.973  1.00 39.01           N  
ATOM    264  CA  GLY A  46     -40.608 -33.715 -10.105  1.00 39.65           C  
ATOM    265  C   GLY A  46     -41.560 -34.569  -9.306  1.00 43.14           C  
ATOM    266  O   GLY A  46     -41.198 -35.657  -8.905  1.00 37.49           O  
ATOM    267  N   ASN A  47     -42.772 -34.105  -9.046  1.00 44.86           N  
ATOM    268  CA  ASN A  47     -43.570 -34.814  -8.035  1.00 47.48           C  
ATOM    269  C   ASN A  47     -44.220 -36.093  -8.534  1.00 43.82           C  
ATOM    270  O   ASN A  47     -44.722 -36.873  -7.741  1.00 41.94           O  
ATOM    271  CB  ASN A  47     -44.594 -33.908  -7.347  1.00 52.11           C  
ATOM    272  CG  ASN A  47     -45.248 -32.964  -8.295  1.00 54.98           C  
ATOM    273  OD1 ASN A  47     -45.116 -31.754  -8.147  1.00 60.68           O  
ATOM    274  ND2 ASN A  47     -45.910 -33.502  -9.310  1.00 54.35           N  
ATOM    275  N   GLN A  48     -44.197 -36.309  -9.839  1.00 42.86           N  
ATOM    276  CA  GLN A  48     -44.579 -37.588 -10.411  1.00 45.12           C  
ATOM    277  C   GLN A  48     -43.407 -38.326 -11.105  1.00 42.19           C  
ATOM    278  O   GLN A  48     -43.627 -39.289 -11.838  1.00 38.68           O  
ATOM    279  CB  GLN A  48     -45.669 -37.323 -11.432  1.00 50.29           C  
ATOM    280  CG  GLN A  48     -46.806 -38.320 -11.386  1.00 61.14           C  
ATOM    281  CD  GLN A  48     -47.768 -38.120 -12.543  1.00 67.20           C  
ATOM    282  OE1 GLN A  48     -47.877 -37.012 -13.079  1.00 66.88           O  
ATOM    283  NE2 GLN A  48     -48.459 -39.192 -12.948  1.00 66.85           N  
ATOM    284  N   TRP A  51     -42.176 -37.870 -10.872  1.00 41.55           N  
ATOM    285  CA  TRP A  51     -41.024 -38.214 -11.725  1.00 39.11           C  
ATOM    286  C   TRP A  51     -39.728 -38.575 -10.991  1.00 37.93           C  
ATOM    287  O   TRP A  51     -39.224 -37.798 -10.179  1.00 35.80           O  
ATOM    288  CB  TRP A  51     -40.714 -37.042 -12.652  1.00 40.63           C  
ATOM    289  CG  TRP A  51     -41.800 -36.725 -13.627  1.00 40.03           C  
ATOM    290  CD1 TRP A  51     -42.648 -35.643 -13.593  1.00 40.87           C  
ATOM    291  CD2 TRP A  51     -42.166 -37.483 -14.780  1.00 40.03           C  
ATOM    292  NE1 TRP A  51     -43.508 -35.688 -14.658  1.00 38.72           N  
ATOM    293  CE2 TRP A  51     -43.232 -36.802 -15.407  1.00 40.20           C  
ATOM    294  CE3 TRP A  51     -41.692 -38.667 -15.356  1.00 39.26           C  
ATOM    295  CZ2 TRP A  51     -43.830 -37.271 -16.573  1.00 40.15           C  
ATOM    296  CZ3 TRP A  51     -42.288 -39.127 -16.501  1.00 38.42           C  
ATOM    297  CH2 TRP A  51     -43.340 -38.436 -17.100  1.00 41.47           C  
ATOM    298  N   ILE A  52     -39.193 -39.757 -11.312  1.00 34.24           N  
ATOM    299  CA  ILE A  52     -37.928 -40.227 -10.797  1.00 31.55           C  
ATOM    300  C   ILE A  52     -36.957 -40.320 -11.962  1.00 31.71           C  
ATOM    301  O   ILE A  52     -37.325 -40.847 -13.012  1.00 30.76           O  
ATOM    302  CB  ILE A  52     -38.055 -41.644 -10.195  1.00 31.89           C  
ATOM    303  CG1 ILE A  52     -39.128 -41.699  -9.078  1.00 32.40           C  
ATOM    304  CG2 ILE A  52     -36.708 -42.118  -9.680  1.00 31.02           C  
ATOM    305  CD1 ILE A  52     -38.947 -40.698  -7.949  1.00 31.82           C  
ATOM    306  N   LEU A  53     -35.731 -39.827 -11.779  1.00 30.30           N  
ATOM    307  CA  LEU A  53     -34.694 -39.931 -12.792  1.00 31.33           C  
ATOM    308  C   LEU A  53     -33.742 -41.011 -12.349  1.00 31.12           C  
ATOM    309  O   LEU A  53     -33.293 -41.026 -11.198  1.00 31.36           O  
ATOM    310  CB  LEU A  53     -33.951 -38.599 -12.999  1.00 31.41           C  
ATOM    311  CG  LEU A  53     -33.061 -38.519 -14.239  1.00 32.49           C  
ATOM    312  CD1 LEU A  53     -33.904 -38.526 -15.506  1.00 32.54           C  
ATOM    313  CD2 LEU A  53     -32.175 -37.276 -14.201  1.00 33.32           C  
ATOM    314  N   THR A  54     -33.462 -41.936 -13.259  1.00 31.30           N  
ATOM    315  CA  THR A  54     -32.661 -43.107 -12.954  1.00 30.43           C  
ATOM    316  C   THR A  54     -31.919 -43.618 -14.209  1.00 31.58           C  
ATOM    317  O   THR A  54     -31.826 -42.909 -15.199  1.00 30.61           O  
ATOM    318  CB  THR A  54     -33.543 -44.197 -12.317  1.00 31.21           C  
ATOM    319  OG1 THR A  54     -32.724 -45.244 -11.780  1.00 30.79           O  
ATOM    320  CG2 THR A  54     -34.553 -44.747 -13.307  1.00 31.56           C  
ATOM    321  N   ALA A  55     -31.356 -44.827 -14.128  1.00 34.14           N  
ATOM    322  CA  ALA A  55     -30.559 -45.415 -15.223  1.00 35.89           C  
ATOM    323  C   ALA A  55     -31.408 -46.361 -16.059  1.00 33.43           C  
ATOM    324  O   ALA A  55     -32.198 -47.135 -15.517  1.00 34.17           O  
ATOM    325  CB  ALA A  55     -29.334 -46.155 -14.658  1.00 34.25           C  
ATOM    326  N   ALA A  56     -31.248 -46.294 -17.374  1.00 35.56           N  
ATOM    327  CA  ALA A  56     -31.940 -47.244 -18.269  1.00 35.57           C  
ATOM    328  C   ALA A  56     -31.627 -48.730 -17.970  1.00 33.13           C  
ATOM    329  O   ALA A  56     -32.509 -49.586 -18.046  1.00 33.80           O  
ATOM    330  CB  ALA A  56     -31.627 -46.932 -19.709  1.00 36.46           C  
ATOM    331  N   HIS A  57     -30.393 -49.029 -17.601  1.00 31.95           N  
ATOM    332  CA  HIS A  57     -29.956 -50.411 -17.503  1.00 33.78           C  
ATOM    333  C   HIS A  57     -30.647 -51.125 -16.364  1.00 34.48           C  
ATOM    334  O   HIS A  57     -30.761 -52.340 -16.382  1.00 36.26           O  
ATOM    335  CB  HIS A  57     -28.433 -50.512 -17.412  1.00 34.39           C  
ATOM    336  CG  HIS A  57     -27.870 -50.165 -16.072  1.00 34.97           C  
ATOM    337  ND1 HIS A  57     -27.141 -49.019 -15.848  1.00 33.75           N  
ATOM    338  CD2 HIS A  57     -27.922 -50.816 -14.888  1.00 35.80           C  
ATOM    339  CE1 HIS A  57     -26.761 -48.982 -14.583  1.00 36.07           C  
ATOM    340  NE2 HIS A  57     -27.232 -50.054 -13.974  1.00 36.82           N  
ATOM    341  N   CYS A  58     -31.171 -50.361 -15.402  1.00 33.83           N  
ATOM    342  CA  CYS A  58     -31.938 -50.937 -14.317  1.00 33.94           C  
ATOM    343  C   CYS A  58     -33.148 -51.779 -14.756  1.00 35.59           C  
ATOM    344  O   CYS A  58     -33.660 -52.600 -13.966  1.00 36.02           O  
ATOM    345  CB  CYS A  58     -32.430 -49.819 -13.390  1.00 36.41           C  
ATOM    346  SG  CYS A  58     -31.121 -49.073 -12.418  1.00 34.85           S  
ATOM    347  N   PHE A  59     -33.623 -51.562 -15.980  1.00 33.63           N  
ATOM    348  CA  PHE A  59     -34.840 -52.196 -16.450  1.00 34.46           C  
ATOM    349  C   PHE A  59     -34.626 -53.386 -17.395  1.00 37.57           C  
ATOM    350  O   PHE A  59     -35.553 -53.843 -18.054  1.00 35.89           O  
ATOM    351  CB  PHE A  59     -35.764 -51.100 -16.994  1.00 35.72           C  
ATOM    352  CG  PHE A  59     -35.995 -50.035 -15.969  1.00 37.41           C  
ATOM    353  CD1 PHE A  59     -36.865 -50.260 -14.907  1.00 40.01           C  
ATOM    354  CD2 PHE A  59     -35.227 -48.880 -15.967  1.00 39.49           C  
ATOM    355  CE1 PHE A  59     -37.037 -49.307 -13.915  1.00 41.82           C  
ATOM    356  CE2 PHE A  59     -35.383 -47.921 -14.969  1.00 41.82           C  
ATOM    357  CZ  PHE A  59     -36.288 -48.131 -13.944  1.00 40.36           C  
ATOM    358  N   TYR A  59A    -33.416 -53.929 -17.399  1.00 35.06           N  
ATOM    359  CA  TYR A  59A    -33.144 -55.127 -18.164  1.00 38.08           C  
ATOM    360  C   TYR A  59A    -34.063 -56.252 -17.667  1.00 36.18           C  
ATOM    361  O   TYR A  59A    -34.104 -56.539 -16.479  1.00 37.15           O  
ATOM    362  CB  TYR A  59A    -31.670 -55.531 -18.006  1.00 37.32           C  
ATOM    363  CG  TYR A  59A    -31.400 -56.845 -18.668  1.00 38.21           C  
ATOM    364  CD1 TYR A  59A    -31.104 -56.910 -20.034  1.00 38.28           C  
ATOM    365  CD2 TYR A  59A    -31.490 -58.024 -17.955  1.00 35.92           C  
ATOM    366  CE1 TYR A  59A    -30.900 -58.118 -20.667  1.00 39.09           C  
ATOM    367  CE2 TYR A  59A    -31.278 -59.242 -18.581  1.00 39.70           C  
ATOM    368  CZ  TYR A  59A    -30.979 -59.273 -19.934  1.00 38.91           C  
ATOM    369  OH  TYR A  59A    -30.772 -60.467 -20.549  1.00 42.59           O  
ATOM    370  N   GLY A  59B    -34.808 -56.890 -18.551  1.00 40.72           N  
ATOM    371  CA  GLY A  59B    -35.693 -57.997 -18.116  1.00 42.45           C  
ATOM    372  C   GLY A  59B    -36.887 -57.578 -17.246  1.00 47.18           C  
ATOM    373  O   GLY A  59B    -37.548 -58.419 -16.619  1.00 44.16           O  
ATOM    374  N   VAL A  59C    -37.163 -56.278 -17.175  1.00 49.15           N  
ATOM    375  CA  VAL A  59C    -38.378 -55.795 -16.519  1.00 50.36           C  
ATOM    376  C   VAL A  59C    -39.383 -55.644 -17.644  1.00 49.17           C  
ATOM    377  O   VAL A  59C    -39.202 -54.791 -18.509  1.00 46.44           O  
ATOM    378  CB  VAL A  59C    -38.159 -54.457 -15.789  1.00 51.07           C  
ATOM    379  CG1 VAL A  59C    -39.467 -53.904 -15.232  1.00 48.69           C  
ATOM    380  CG2 VAL A  59C    -37.136 -54.634 -14.684  1.00 48.20           C  
ATOM    381  N   GLU A  60     -40.409 -56.504 -17.635  1.00 52.56           N  
ATOM    382  CA  GLU A  60     -41.402 -56.602 -18.722  1.00 54.78           C  
ATOM    383  C   GLU A  60     -42.591 -55.674 -18.491  1.00 55.55           C  
ATOM    384  O   GLU A  60     -43.353 -55.399 -19.413  1.00 57.29           O  
ATOM    385  CB  GLU A  60     -41.923 -58.044 -18.837  1.00 57.37           C  
ATOM    386  CG  GLU A  60     -40.845 -59.098 -19.051  0.50 57.87           C  
ATOM    387  CD  GLU A  60     -39.923 -58.751 -20.205  0.50 59.59           C  
ATOM    388  OE1 GLU A  60     -40.435 -58.424 -21.297  0.50 59.90           O  
ATOM    389  OE2 GLU A  60     -38.687 -58.787 -20.018  0.50 60.79           O  
ATOM    390  N   SER A  61     -42.737 -55.191 -17.260  1.00 52.87           N  
ATOM    391  CA  SER A  61     -43.900 -54.411 -16.862  1.00 50.31           C  
ATOM    392  C   SER A  61     -43.594 -53.459 -15.701  1.00 43.47           C  
ATOM    393  O   SER A  61     -42.905 -53.823 -14.767  1.00 44.07           O  
ATOM    394  CB  SER A  61     -45.024 -55.368 -16.450  1.00 50.02           C  
ATOM    395  OG  SER A  61     -46.067 -54.678 -15.781  1.00 52.12           O  
ATOM    396  N   PRO A  62     -44.145 -52.243 -15.735  1.00 44.41           N  
ATOM    397  CA  PRO A  62     -44.070 -51.389 -14.535  1.00 42.21           C  
ATOM    398  C   PRO A  62     -44.787 -51.923 -13.287  1.00 40.35           C  
ATOM    399  O   PRO A  62     -44.568 -51.407 -12.181  1.00 39.41           O  
ATOM    400  CB  PRO A  62     -44.728 -50.094 -14.999  1.00 42.80           C  
ATOM    401  CG  PRO A  62     -45.559 -50.481 -16.182  1.00 42.32           C  
ATOM    402  CD  PRO A  62     -44.775 -51.542 -16.866  1.00 42.38           C  
ATOM    403  N   LYS A  63     -45.619 -52.955 -13.447  1.00 41.66           N  
ATOM    404  CA  LYS A  63     -46.454 -53.458 -12.348  1.00 40.09           C  
ATOM    405  C   LYS A  63     -45.696 -54.066 -11.180  1.00 39.89           C  
ATOM    406  O   LYS A  63     -46.200 -54.064 -10.044  1.00 37.16           O  
ATOM    407  CB  LYS A  63     -47.459 -54.484 -12.881  1.00 46.50           C  
ATOM    408  CG  LYS A  63     -48.459 -53.895 -13.865  1.00 51.31           C  
ATOM    409  CD  LYS A  63     -49.734 -54.733 -13.937  1.00 55.50           C  
ATOM    410  CE  LYS A  63     -50.781 -54.061 -14.814  1.00 61.14           C  
ATOM    411  NZ  LYS A  63     -52.140 -54.628 -14.585  1.00 66.42           N  
ATOM    412  N   ILE A  64     -44.483 -54.553 -11.441  1.00 38.60           N  
ATOM    413  CA  ILE A  64     -43.634 -55.182 -10.400  1.00 41.78           C  
ATOM    414  C   ILE A  64     -42.671 -54.211  -9.706  1.00 40.37           C  
ATOM    415  O   ILE A  64     -41.837 -54.639  -8.896  1.00 37.45           O  
ATOM    416  CB  ILE A  64     -42.769 -56.317 -10.993  1.00 43.69           C  
ATOM    417  CG1 ILE A  64     -41.852 -55.770 -12.083  1.00 43.96           C  
ATOM    418  CG2 ILE A  64     -43.652 -57.432 -11.553  1.00 43.37           C  
ATOM    419  CD1 ILE A  64     -40.814 -56.768 -12.555  1.00 49.04           C  
ATOM    420  N   LEU A  65     -42.776 -52.921 -10.041  1.00 38.56           N  
ATOM    421  CA  LEU A  65     -41.868 -51.900  -9.532  1.00 35.20           C  
ATOM    422  C   LEU A  65     -42.501 -51.158  -8.382  1.00 37.33           C  
ATOM    423  O   LEU A  65     -43.657 -50.783  -8.457  1.00 37.56           O  
ATOM    424  CB  LEU A  65     -41.517 -50.897 -10.628  1.00 35.39           C  
ATOM    425  CG  LEU A  65     -40.616 -51.393 -11.762  1.00 35.21           C  
ATOM    426  CD1 LEU A  65     -40.326 -50.250 -12.716  1.00 33.97           C  
ATOM    427  CD2 LEU A  65     -39.305 -52.003 -11.260  1.00 33.97           C  
ATOM    428  N   ARG A  66     -41.724 -50.921  -7.336  1.00 36.22           N  
ATOM    429  CA  ARG A  66     -42.153 -50.079  -6.252  1.00 37.47           C  
ATOM    430  C   ARG A  66     -41.047 -49.051  -5.993  1.00 37.93           C  
ATOM    431  O   ARG A  66     -39.863 -49.416  -5.996  1.00 36.24           O  
ATOM    432  CB  ARG A  66     -42.417 -50.934  -5.015  1.00 38.12           C  
ATOM    433  CG  ARG A  66     -43.509 -51.988  -5.198  1.00 39.89           C  
ATOM    434  CD  ARG A  66     -43.766 -52.715  -3.881  1.00 39.89           C  
ATOM    435  NE  ARG A  66     -45.018 -53.464  -3.882  1.00 39.19           N  
ATOM    436  CZ  ARG A  66     -45.591 -53.984  -2.792  1.00 37.82           C  
ATOM    437  NH1 ARG A  66     -45.041 -53.872  -1.599  1.00 34.17           N  
ATOM    438  NH2 ARG A  66     -46.741 -54.627  -2.901  1.00 40.02           N  
ATOM    439  N   VAL A  67     -41.434 -47.781  -5.823  1.00 34.02           N  
ATOM    440  CA  VAL A  67     -40.498 -46.715  -5.465  1.00 33.00           C  
ATOM    441  C   VAL A  67     -40.730 -46.286  -4.026  1.00 33.25           C  
ATOM    442  O   VAL A  67     -41.847 -45.909  -3.674  1.00 34.67           O  
ATOM    443  CB  VAL A  67     -40.663 -45.495  -6.370  1.00 32.72           C  
ATOM    444  CG1 VAL A  67     -39.740 -44.362  -5.926  1.00 33.54           C  
ATOM    445  CG2 VAL A  67     -40.438 -45.879  -7.820  1.00 34.19           C  
ATOM    446  N   TYR A  68     -39.674 -46.345  -3.206  1.00 33.47           N  
ATOM    447  CA  TYR A  68     -39.714 -45.903  -1.811  1.00 33.19           C  
ATOM    448  C   TYR A  68     -38.905 -44.631  -1.589  1.00 36.93           C  
ATOM    449  O   TYR A  68     -37.720 -44.530  -2.000  1.00 31.15           O  
ATOM    450  CB  TYR A  68     -39.191 -46.977  -0.869  1.00 35.46           C  
ATOM    451  CG  TYR A  68     -40.034 -48.216  -0.846  1.00 34.37           C  
ATOM    452  CD1 TYR A  68     -39.899 -49.198  -1.838  1.00 35.42           C  
ATOM    453  CD2 TYR A  68     -40.974 -48.413   0.151  1.00 33.80           C  
ATOM    454  CE1 TYR A  68     -40.678 -50.350  -1.820  1.00 35.47           C  
ATOM    455  CE2 TYR A  68     -41.759 -49.557   0.174  1.00 32.68           C  
ATOM    456  CZ  TYR A  68     -41.614 -50.520  -0.813  1.00 33.48           C  
ATOM    457  OH  TYR A  68     -42.389 -51.651  -0.799  1.00 30.90           O  
ATOM    458  N   SER A  69     -39.575 -43.659  -0.950  1.00 36.36           N  
ATOM    459  CA  SER A  69     -39.012 -42.331  -0.696  1.00 34.32           C  
ATOM    460  C   SER A  69     -38.893 -42.157   0.803  1.00 34.19           C  
ATOM    461  O   SER A  69     -39.511 -42.884   1.554  1.00 30.23           O  
ATOM    462  CB  SER A  69     -39.879 -41.220  -1.307  1.00 35.75           C  
ATOM    463  OG  SER A  69     -41.232 -41.206  -0.828  1.00 34.75           O  
ATOM    464  N   GLY A  70     -38.071 -41.213   1.228  1.00 33.32           N  
ATOM    465  CA  GLY A  70     -37.925 -40.934   2.648  1.00 35.17           C  
ATOM    466  C   GLY A  70     -37.304 -42.077   3.392  1.00 36.53           C  
ATOM    467  O   GLY A  70     -37.453 -42.177   4.600  1.00 40.44           O  
ATOM    468  N   ILE A  71     -36.581 -42.939   2.682  1.00 37.25           N  
ATOM    469  CA  ILE A  71     -36.003 -44.126   3.301  1.00 35.20           C  
ATOM    470  C   ILE A  71     -34.570 -43.817   3.690  1.00 30.92           C  
ATOM    471  O   ILE A  71     -33.832 -43.297   2.889  1.00 32.06           O  
ATOM    472  CB  ILE A  71     -36.027 -45.326   2.317  1.00 36.69           C  
ATOM    473  CG1 ILE A  71     -37.469 -45.664   1.918  1.00 38.39           C  
ATOM    474  CG2 ILE A  71     -35.293 -46.521   2.893  1.00 36.33           C  
ATOM    475  CD1 ILE A  71     -38.398 -46.005   3.073  1.00 37.00           C  
ATOM    476  N   LEU A  72     -34.184 -44.168   4.915  1.00 33.64           N  
ATOM    477  CA  LEU A  72     -32.784 -44.220   5.309  1.00 33.84           C  
ATOM    478  C   LEU A  72     -32.329 -45.672   5.312  1.00 35.25           C  
ATOM    479  O   LEU A  72     -31.393 -46.011   4.614  1.00 36.40           O  
ATOM    480  CB  LEU A  72     -32.525 -43.612   6.693  1.00 36.29           C  
ATOM    481  CG  LEU A  72     -31.073 -43.697   7.229  1.00 35.78           C  
ATOM    482  CD1 LEU A  72     -30.142 -42.865   6.362  1.00 35.00           C  
ATOM    483  CD2 LEU A  72     -30.930 -43.257   8.693  1.00 37.59           C  
ATOM    484  N   ASN A  73     -33.003 -46.508   6.103  1.00 34.76           N  
ATOM    485  CA  ASN A  73     -32.680 -47.915   6.242  1.00 33.16           C  
ATOM    486  C   ASN A  73     -33.641 -48.854   5.540  1.00 35.59           C  
ATOM    487  O   ASN A  73     -34.871 -48.751   5.727  1.00 32.97           O  
ATOM    488  CB  ASN A  73     -32.633 -48.297   7.721  1.00 35.87           C  
ATOM    489  CG  ASN A  73     -31.599 -47.524   8.476  1.00 34.53           C  
ATOM    490  OD1 ASN A  73     -30.455 -47.439   8.068  1.00 36.41           O  
ATOM    491  ND2 ASN A  73     -31.998 -46.956   9.599  1.00 36.10           N  
ATOM    492  N   GLN A  74     -33.080 -49.788   4.755  1.00 36.02           N  
ATOM    493  CA  GLN A  74     -33.861 -50.813   4.019  1.00 34.01           C  
ATOM    494  C   GLN A  74     -34.774 -51.600   4.950  1.00 34.15           C  
ATOM    495  O   GLN A  74     -35.790 -52.156   4.526  1.00 39.06           O  
ATOM    496  CB  GLN A  74     -32.928 -51.807   3.267  1.00 32.79           C  
ATOM    497  CG  GLN A  74     -32.152 -51.224   2.080  1.00 33.51           C  
ATOM    498  CD  GLN A  74     -33.010 -50.824   0.885  1.00 31.20           C  
ATOM    499  OE1 GLN A  74     -32.662 -49.923   0.089  1.00 36.59           O  
ATOM    500  NE2 GLN A  74     -34.125 -51.462   0.750  1.00 29.86           N  
ATOM    501  N   ALA A  75     -34.413 -51.663   6.223  1.00 35.34           N  
ATOM    502  CA  ALA A  75     -35.265 -52.298   7.221  1.00 38.50           C  
ATOM    503  C   ALA A  75     -36.583 -51.514   7.532  1.00 39.04           C  
ATOM    504  O   ALA A  75     -37.482 -52.057   8.150  1.00 37.04           O  
ATOM    505  CB  ALA A  75     -34.470 -52.521   8.497  1.00 39.35           C  
ATOM    506  N   GLU A  76     -36.685 -50.259   7.109  1.00 37.88           N  
ATOM    507  CA  GLU A  76     -37.945 -49.514   7.161  1.00 35.94           C  
ATOM    508  C   GLU A  76     -38.972 -50.105   6.202  1.00 37.13           C  
ATOM    509  O   GLU A  76     -40.177 -49.853   6.342  1.00 35.06           O  
ATOM    510  CB  GLU A  76     -37.731 -48.050   6.754  1.00 35.29           C  
ATOM    511  CG  GLU A  76     -36.820 -47.264   7.675  1.00 35.32           C  
ATOM    512  CD  GLU A  76     -36.509 -45.897   7.131  1.00 34.82           C  
ATOM    513  OE1 GLU A  76     -37.410 -45.270   6.543  1.00 35.74           O  
ATOM    514  OE2 GLU A  76     -35.358 -45.450   7.292  1.00 36.40           O  
ATOM    515  N   ILE A  77     -38.492 -50.837   5.193  1.00 35.34           N  
ATOM    516  CA  ILE A  77     -39.359 -51.370   4.160  1.00 33.88           C  
ATOM    517  C   ILE A  77     -39.865 -52.751   4.550  1.00 37.70           C  
ATOM    518  O   ILE A  77     -39.092 -53.690   4.706  1.00 36.07           O  
ATOM    519  CB  ILE A  77     -38.665 -51.427   2.791  1.00 33.12           C  
ATOM    520  CG1 ILE A  77     -38.308 -50.012   2.339  1.00 32.80           C  
ATOM    521  CG2 ILE A  77     -39.562 -52.055   1.737  1.00 33.13           C  
ATOM    522  CD1 ILE A  77     -37.275 -49.987   1.239  1.00 33.89           C  
ATOM    523  N   ALA A  78     -41.179 -52.857   4.669  1.00 39.00           N  
ATOM    524  CA  ALA A  78     -41.849 -54.108   5.003  1.00 40.11           C  
ATOM    525  C   ALA A  78     -43.122 -54.163   4.211  1.00 39.30           C  
ATOM    526  O   ALA A  78     -43.435 -53.227   3.480  1.00 38.14           O  
ATOM    527  CB  ALA A  78     -42.170 -54.169   6.492  1.00 39.47           C  
ATOM    528  N   GLU A  79     -43.874 -55.247   4.383  1.00 40.01           N  
ATOM    529  CA  GLU A  79     -45.135 -55.426   3.664  1.00 43.51           C  
ATOM    530  C   GLU A  79     -46.109 -54.248   3.879  1.00 39.70           C  
ATOM    531  O   GLU A  79     -46.856 -53.897   3.001  1.00 38.92           O  
ATOM    532  CB  GLU A  79     -45.783 -56.756   4.095  1.00 48.85           C  
ATOM    533  CG  GLU A  79     -47.196 -57.009   3.574  1.00 51.99           C  
ATOM    534  CD  GLU A  79     -48.295 -56.297   4.367  1.00 55.93           C  
ATOM    535  OE1 GLU A  79     -48.160 -56.136   5.607  1.00 57.80           O  
ATOM    536  OE2 GLU A  79     -49.309 -55.899   3.739  1.00 56.85           O  
ATOM    537  N   ASP A  80     -46.091 -53.630   5.049  1.00 41.04           N  
ATOM    538  CA  ASP A  80     -47.079 -52.585   5.348  1.00 40.00           C  
ATOM    539  C   ASP A  80     -46.563 -51.163   5.034  1.00 40.80           C  
ATOM    540  O   ASP A  80     -47.266 -50.161   5.258  1.00 40.77           O  
ATOM    541  CB  ASP A  80     -47.528 -52.710   6.806  1.00 38.76           C  
ATOM    542  CG  ASP A  80     -46.383 -52.613   7.781  1.00 38.73           C  
ATOM    543  OD1 ASP A  80     -45.215 -52.522   7.353  1.00 41.63           O  
ATOM    544  OD2 ASP A  80     -46.649 -52.613   8.995  1.00 44.63           O  
ATOM    545  N   THR A  81     -45.350 -51.073   4.499  1.00 39.83           N  
ATOM    546  CA  THR A  81     -44.770 -49.785   4.139  1.00 37.33           C  
ATOM    547  C   THR A  81     -45.368 -49.224   2.840  1.00 38.55           C  
ATOM    548  O   THR A  81     -45.499 -49.929   1.841  1.00 37.93           O  
ATOM    549  CB  THR A  81     -43.239 -49.899   4.059  1.00 36.61           C  
ATOM    550  OG1 THR A  81     -42.746 -50.445   5.296  1.00 33.18           O  
ATOM    551  CG2 THR A  81     -42.599 -48.543   3.837  1.00 34.63           C  
ATOM    552  N   SER A  81A    -45.715 -47.934   2.840  1.00 38.58           N  
ATOM    553  CA  SER A  81A    -46.277 -47.315   1.635  1.00 37.45           C  
ATOM    554  C   SER A  81A    -45.209 -47.021   0.585  1.00 37.82           C  
ATOM    555  O   SER A  81A    -44.055 -46.793   0.916  1.00 34.12           O  
ATOM    556  CB  SER A  81A    -47.031 -46.035   1.971  1.00 37.46           C  
ATOM    557  OG  SER A  81A    -46.160 -45.144   2.621  1.00 42.25           O  
ATOM    558  N   PHE A  82     -45.626 -47.030  -0.676  1.00 35.38           N  
ATOM    559  CA  PHE A  82     -44.729 -46.861  -1.804  1.00 38.96           C  
ATOM    560  C   PHE A  82     -45.504 -46.210  -2.924  1.00 36.99           C  
ATOM    561  O   PHE A  82     -46.710 -46.104  -2.845  1.00 36.78           O  
ATOM    562  CB  PHE A  82     -44.199 -48.223  -2.270  1.00 37.18           C  
ATOM    563  CG  PHE A  82     -45.276 -49.181  -2.660  1.00 37.06           C  
ATOM    564  CD1 PHE A  82     -45.879 -49.986  -1.705  1.00 39.69           C  
ATOM    565  CD2 PHE A  82     -45.723 -49.258  -3.973  1.00 38.13           C  
ATOM    566  CE1 PHE A  82     -46.898 -50.861  -2.056  1.00 38.62           C  
ATOM    567  CE2 PHE A  82     -46.737 -50.131  -4.336  1.00 38.49           C  
ATOM    568  CZ  PHE A  82     -47.321 -50.936  -3.374  1.00 39.93           C  
ATOM    569  N   PHE A  83     -44.797 -45.773  -3.962  1.00 37.16           N  
ATOM    570  CA  PHE A  83     -45.417 -45.245  -5.175  1.00 34.72           C  
ATOM    571  C   PHE A  83     -45.311 -46.294  -6.234  1.00 35.33           C  
ATOM    572  O   PHE A  83     -44.228 -46.795  -6.483  1.00 33.70           O  
ATOM    573  CB  PHE A  83     -44.663 -44.000  -5.640  1.00 37.11           C  
ATOM    574  CG  PHE A  83     -44.709 -42.892  -4.653  1.00 35.58           C  
ATOM    575  CD1 PHE A  83     -45.788 -42.012  -4.634  1.00 37.77           C  
ATOM    576  CD2 PHE A  83     -43.733 -42.768  -3.694  1.00 34.69           C  
ATOM    577  CE1 PHE A  83     -45.863 -41.001  -3.689  1.00 37.45           C  
ATOM    578  CE2 PHE A  83     -43.793 -41.763  -2.746  1.00 35.88           C  
ATOM    579  CZ  PHE A  83     -44.858 -40.885  -2.728  1.00 37.45           C  
ATOM    580  N   GLY A  84     -46.431 -46.637  -6.861  1.00 35.05           N  
ATOM    581  CA  GLY A  84     -46.415 -47.463  -8.054  1.00 33.25           C  
ATOM    582  C   GLY A  84     -45.921 -46.697  -9.261  1.00 35.30           C  
ATOM    583  O   GLY A  84     -45.901 -45.477  -9.271  1.00 32.74           O  
ATOM    584  N   VAL A  85     -45.538 -47.424 -10.302  1.00 37.22           N  
ATOM    585  CA  VAL A  85     -45.004 -46.814 -11.511  1.00 38.08           C  
ATOM    586  C   VAL A  85     -46.053 -46.958 -12.595  1.00 38.52           C  
ATOM    587  O   VAL A  85     -46.515 -48.043 -12.863  1.00 37.68           O  
ATOM    588  CB  VAL A  85     -43.702 -47.514 -11.936  1.00 38.97           C  
ATOM    589  CG1 VAL A  85     -43.150 -46.922 -13.229  1.00 39.42           C  
ATOM    590  CG2 VAL A  85     -42.674 -47.416 -10.810  1.00 39.51           C  
ATOM    591  N   GLN A  86     -46.432 -45.844 -13.202  1.00 39.81           N  
ATOM    592  CA  GLN A  86     -47.422 -45.850 -14.253  1.00 41.65           C  
ATOM    593  C   GLN A  86     -46.712 -46.171 -15.547  1.00 41.61           C  
ATOM    594  O   GLN A  86     -47.258 -46.855 -16.404  1.00 41.13           O  
ATOM    595  CB  GLN A  86     -48.123 -44.494 -14.328  1.00 43.52           C  
ATOM    596  CG  GLN A  86     -49.112 -44.327 -15.459  1.00 47.18           C  
ATOM    597  CD  GLN A  86     -49.727 -42.928 -15.488  1.00 50.72           C  
ATOM    598  OE1 GLN A  86     -49.671 -42.236 -16.504  1.00 53.73           O  
ATOM    599  NE2 GLN A  86     -50.302 -42.502 -14.366  1.00 51.09           N  
ATOM    600  N   GLU A  87     -45.475 -45.703 -15.680  1.00 41.69           N  
ATOM    601  CA  GLU A  87     -44.755 -45.878 -16.945  1.00 44.59           C  
ATOM    602  C   GLU A  87     -43.237 -45.811 -16.781  1.00 40.86           C  
ATOM    603  O   GLU A  87     -42.727 -45.027 -15.990  1.00 42.13           O  
ATOM    604  CB  GLU A  87     -45.233 -44.824 -17.932  1.00 44.34           C  
ATOM    605  CG  GLU A  87     -44.613 -44.913 -19.310  1.00 47.22           C  
ATOM    606  CD  GLU A  87     -45.177 -43.869 -20.243  1.00 48.01           C  
ATOM    607  OE1 GLU A  87     -46.040 -43.101 -19.803  1.00 50.75           O  
ATOM    608  OE2 GLU A  87     -44.745 -43.802 -21.404  1.00 56.90           O  
ATOM    609  N   ILE A  88     -42.540 -46.669 -17.516  1.00 40.90           N  
ATOM    610  CA  ILE A  88     -41.082 -46.651 -17.606  1.00 40.23           C  
ATOM    611  C   ILE A  88     -40.718 -45.961 -18.919  1.00 40.40           C  
ATOM    612  O   ILE A  88     -41.195 -46.357 -19.976  1.00 42.10           O  
ATOM    613  CB  ILE A  88     -40.489 -48.072 -17.588  1.00 40.45           C  
ATOM    614  CG1 ILE A  88     -40.947 -48.840 -16.348  1.00 43.20           C  
ATOM    615  CG2 ILE A  88     -38.970 -48.013 -17.602  1.00 40.07           C  
ATOM    616  CD1 ILE A  88     -40.874 -50.357 -16.500  1.00 40.79           C  
ATOM    617  N   ILE A  89     -39.921 -44.894 -18.868  1.00 39.45           N  
ATOM    618  CA  ILE A  89     -39.524 -44.218 -20.104  1.00 38.32           C  
ATOM    619  C   ILE A  89     -38.007 -44.332 -20.221  1.00 38.84           C  
ATOM    620  O   ILE A  89     -37.278 -43.776 -19.404  1.00 42.15           O  
ATOM    621  CB  ILE A  89     -39.969 -42.729 -20.160  1.00 39.69           C  
ATOM    622  CG1 ILE A  89     -41.482 -42.598 -19.992  1.00 40.20           C  
ATOM    623  CG2 ILE A  89     -39.585 -42.106 -21.496  1.00 41.22           C  
ATOM    624  CD1 ILE A  89     -41.983 -41.166 -19.939  1.00 42.30           C  
ATOM    625  N   ILE A  90     -37.548 -45.057 -21.233  1.00 37.44           N  
ATOM    626  CA  ILE A  90     -36.116 -45.267 -21.506  1.00 38.22           C  
ATOM    627  C   ILE A  90     -35.708 -44.422 -22.722  1.00 38.53           C  
ATOM    628  O   ILE A  90     -36.441 -44.363 -23.682  1.00 39.06           O  
ATOM    629  CB  ILE A  90     -35.870 -46.766 -21.758  1.00 38.47           C  
ATOM    630  CG1 ILE A  90     -36.001 -47.543 -20.435  1.00 40.86           C  
ATOM    631  CG2 ILE A  90     -34.505 -47.023 -22.389  1.00 38.19           C  
ATOM    632  CD1 ILE A  90     -36.462 -48.966 -20.623  1.00 44.35           C  
ATOM    633  N   HIS A  91     -34.551 -43.766 -22.685  1.00 36.55           N  
ATOM    634  CA  HIS A  91     -34.083 -43.000 -23.850  1.00 36.82           C  
ATOM    635  C   HIS A  91     -34.035 -43.890 -25.089  1.00 41.43           C  
ATOM    636  O   HIS A  91     -33.464 -44.982 -25.048  1.00 37.72           O  
ATOM    637  CB  HIS A  91     -32.681 -42.473 -23.613  1.00 35.72           C  
ATOM    638  CG  HIS A  91     -32.313 -41.328 -24.498  1.00 36.56           C  
ATOM    639  ND1 HIS A  91     -31.999 -41.487 -25.825  1.00 37.94           N  
ATOM    640  CD2 HIS A  91     -32.209 -40.003 -24.242  1.00 34.67           C  
ATOM    641  CE1 HIS A  91     -31.728 -40.308 -26.355  1.00 40.78           C  
ATOM    642  NE2 HIS A  91     -31.840 -39.392 -25.409  1.00 38.13           N  
ATOM    643  N   ASP A  92     -34.589 -43.416 -26.201  1.00 43.11           N  
ATOM    644  CA  ASP A  92     -34.775 -44.291 -27.361  1.00 46.61           C  
ATOM    645  C   ASP A  92     -33.474 -44.744 -28.032  1.00 45.33           C  
ATOM    646  O   ASP A  92     -33.489 -45.717 -28.774  1.00 46.35           O  
ATOM    647  CB  ASP A  92     -35.742 -43.675 -28.378  1.00 52.33           C  
ATOM    648  CG  ASP A  92     -35.155 -42.507 -29.101  1.00 57.76           C  
ATOM    649  OD1 ASP A  92     -34.305 -41.800 -28.520  1.00 70.75           O  
ATOM    650  OD2 ASP A  92     -35.547 -42.285 -30.257  1.00 71.53           O  
ATOM    651  N   GLN A  93     -32.364 -44.056 -27.737  1.00 41.94           N  
ATOM    652  CA  GLN A  93     -31.026 -44.412 -28.207  1.00 41.72           C  
ATOM    653  C   GLN A  93     -30.136 -45.195 -27.230  1.00 41.07           C  
ATOM    654  O   GLN A  93     -28.944 -45.345 -27.470  1.00 43.93           O  
ATOM    655  CB  GLN A  93     -30.270 -43.133 -28.583  1.00 44.81           C  
ATOM    656  CG  GLN A  93     -30.835 -42.390 -29.783  1.00 44.80           C  
ATOM    657  CD  GLN A  93     -30.006 -41.164 -30.069  1.00 49.15           C  
ATOM    658  OE1 GLN A  93     -28.844 -41.276 -30.441  1.00 54.17           O  
ATOM    659  NE2 GLN A  93     -30.576 -39.989 -29.851  1.00 49.48           N  
ATOM    660  N   TYR A  94     -30.693 -45.653 -26.115  1.00 39.37           N  
ATOM    661  CA  TYR A  94     -29.949 -46.488 -25.175  1.00 36.55           C  
ATOM    662  C   TYR A  94     -29.815 -47.890 -25.718  1.00 36.03           C  
ATOM    663  O   TYR A  94     -30.807 -48.481 -26.132  1.00 33.04           O  
ATOM    664  CB  TYR A  94     -30.682 -46.609 -23.848  1.00 34.31           C  
ATOM    665  CG  TYR A  94     -30.149 -47.720 -22.962  1.00 34.63           C  
ATOM    666  CD1 TYR A  94     -28.981 -47.550 -22.238  1.00 35.54           C  
ATOM    667  CD2 TYR A  94     -30.822 -48.934 -22.847  1.00 34.11           C  
ATOM    668  CE1 TYR A  94     -28.499 -48.553 -21.415  1.00 36.88           C  
ATOM    669  CE2 TYR A  94     -30.346 -49.940 -22.026  1.00 36.90           C  
ATOM    670  CZ  TYR A  94     -29.186 -49.744 -21.313  1.00 34.31           C  
ATOM    671  OH  TYR A  94     -28.707 -50.740 -20.506  1.00 38.52           O  
ATOM    672  N   LYS A  95     -28.603 -48.427 -25.649  1.00 37.21           N  
ATOM    673  CA  LYS A  95     -28.364 -49.847 -25.893  1.00 38.84           C  
ATOM    674  C   LYS A  95     -27.776 -50.543 -24.679  1.00 37.69           C  
ATOM    675  O   LYS A  95     -28.191 -51.620 -24.328  1.00 37.24           O  
ATOM    676  CB  LYS A  95     -27.419 -49.990 -27.084  1.00 43.53           C  
ATOM    677  CG  LYS A  95     -27.966 -49.342 -28.343  1.00 47.69           C  
ATOM    678  CD  LYS A  95     -29.326 -49.929 -28.743  1.00 53.33           C  
ATOM    679  CE  LYS A  95     -29.885 -49.276 -29.992  1.00 60.43           C  
ATOM    680  NZ  LYS A  95     -28.856 -49.191 -31.068  1.00 67.56           N  
ATOM    681  N   MET A  96     -26.790 -49.909 -24.063  1.00 38.84           N  
ATOM    682  CA  MET A  96     -26.177 -50.386 -22.828  1.00 41.75           C  
ATOM    683  C   MET A  96     -25.373 -49.301 -22.128  1.00 38.38           C  
ATOM    684  O   MET A  96     -24.932 -48.322 -22.747  1.00 34.12           O  
ATOM    685  CB  MET A  96     -25.263 -51.548 -23.086  1.00 46.67           C  
ATOM    686  CG  MET A  96     -24.239 -51.286 -24.167  1.00 50.43           C  
ATOM    687  SD  MET A  96     -23.657 -52.887 -24.727  1.00 60.62           S  
ATOM    688  CE  MET A  96     -25.222 -53.635 -25.224  1.00 61.64           C  
ATOM    689  N   ALA A  97     -25.191 -49.511 -20.826  1.00 36.61           N  
ATOM    690  CA  ALA A  97     -24.614 -48.502 -19.956  1.00 37.40           C  
ATOM    691  C   ALA A  97     -23.328 -47.941 -20.565  1.00 35.70           C  
ATOM    692  O   ALA A  97     -23.184 -46.736 -20.713  1.00 33.78           O  
ATOM    693  CB  ALA A  97     -24.361 -49.072 -18.577  1.00 36.79           C  
ATOM    694  N   GLU A  98     -22.439 -48.820 -20.985  1.00 35.00           N  
ATOM    695  CA  GLU A  98     -21.120 -48.404 -21.444  1.00 36.69           C  
ATOM    696  C   GLU A  98     -21.076 -47.594 -22.742  1.00 36.34           C  
ATOM    697  O   GLU A  98     -20.105 -46.916 -23.010  1.00 35.90           O  
ATOM    698  CB  GLU A  98     -20.224 -49.628 -21.576  1.00 41.22           C  
ATOM    699  CG  GLU A  98     -19.941 -50.310 -20.241  1.00 41.38           C  
ATOM    700  CD  GLU A  98     -19.407 -51.701 -20.437  1.00 46.44           C  
ATOM    701  OE1 GLU A  98     -18.171 -51.856 -20.555  1.00 42.90           O  
ATOM    702  OE2 GLU A  98     -20.246 -52.621 -20.508  1.00 52.71           O  
ATOM    703  N   SER A  99     -22.107 -47.663 -23.555  1.00 37.62           N  
ATOM    704  CA  SER A  99     -22.146 -46.826 -24.765  1.00 40.37           C  
ATOM    705  C   SER A  99     -23.022 -45.590 -24.571  1.00 40.19           C  
ATOM    706  O   SER A  99     -23.241 -44.845 -25.502  1.00 45.49           O  
ATOM    707  CB  SER A  99     -22.605 -47.656 -25.960  1.00 40.65           C  
ATOM    708  OG  SER A  99     -23.797 -48.320 -25.651  1.00 48.76           O  
ATOM    709  N   GLY A 100     -23.527 -45.372 -23.355  1.00 36.31           N  
ATOM    710  CA  GLY A 100     -24.147 -44.088 -23.002  1.00 36.25           C  
ATOM    711  C   GLY A 100     -25.650 -44.086 -23.098  1.00 35.61           C  
ATOM    712  O   GLY A 100     -26.288 -45.157 -23.182  1.00 35.28           O  
ATOM    713  N   TYR A 101     -26.229 -42.883 -23.070  1.00 35.92           N  
ATOM    714  CA  TYR A 101     -27.690 -42.711 -23.018  1.00 36.80           C  
ATOM    715  C   TYR A 101     -28.364 -43.509 -21.917  1.00 33.92           C  
ATOM    716  O   TYR A 101     -29.544 -43.855 -22.022  1.00 37.34           O  
ATOM    717  CB  TYR A 101     -28.327 -43.055 -24.383  1.00 41.41           C  
ATOM    718  CG  TYR A 101     -27.851 -42.147 -25.501  1.00 40.79           C  
ATOM    719  CD1 TYR A 101     -28.477 -40.922 -25.748  1.00 46.25           C  
ATOM    720  CD2 TYR A 101     -26.763 -42.496 -26.291  1.00 45.00           C  
ATOM    721  CE1 TYR A 101     -28.030 -40.075 -26.752  1.00 45.42           C  
ATOM    722  CE2 TYR A 101     -26.309 -41.661 -27.305  1.00 45.89           C  
ATOM    723  CZ  TYR A 101     -26.947 -40.449 -27.526  1.00 47.45           C  
ATOM    724  OH  TYR A 101     -26.495 -39.612 -28.518  1.00 50.05           O  
ATOM    725  N   ASP A 102     -27.615 -43.790 -20.856  1.00 34.58           N  
ATOM    726  CA  ASP A 102     -28.102 -44.593 -19.758  1.00 35.37           C  
ATOM    727  C   ASP A 102     -28.941 -43.666 -18.878  1.00 35.73           C  
ATOM    728  O   ASP A 102     -28.466 -43.115 -17.913  1.00 35.83           O  
ATOM    729  CB  ASP A 102     -26.933 -45.214 -18.997  1.00 33.21           C  
ATOM    730  CG  ASP A 102     -27.352 -46.349 -18.078  1.00 33.63           C  
ATOM    731  OD1 ASP A 102     -28.529 -46.797 -18.098  1.00 34.58           O  
ATOM    732  OD2 ASP A 102     -26.471 -46.794 -17.306  1.00 32.74           O  
ATOM    733  N   ILE A 103     -30.209 -43.539 -19.237  1.00 37.10           N  
ATOM    734  CA  ILE A 103     -31.109 -42.594 -18.603  1.00 35.96           C  
ATOM    735  C   ILE A 103     -32.533 -43.042 -18.855  1.00 36.77           C  
ATOM    736  O   ILE A 103     -32.898 -43.509 -19.957  1.00 33.28           O  
ATOM    737  CB  ILE A 103     -30.877 -41.149 -19.115  1.00 37.45           C  
ATOM    738  CG1 ILE A 103     -31.667 -40.115 -18.266  1.00 37.32           C  
ATOM    739  CG2 ILE A 103     -31.189 -41.059 -20.607  1.00 36.56           C  
ATOM    740  CD1 ILE A 103     -31.018 -38.726 -18.200  1.00 39.54           C  
ATOM    741  N   ALA A 104     -33.314 -42.966 -17.794  1.00 35.40           N  
ATOM    742  CA  ALA A 104     -34.698 -43.365 -17.822  1.00 35.59           C  
ATOM    743  C   ALA A 104     -35.479 -42.539 -16.805  1.00 35.68           C  
ATOM    744  O   ALA A 104     -34.910 -42.066 -15.819  1.00 31.55           O  
ATOM    745  CB  ALA A 104     -34.837 -44.839 -17.497  1.00 38.24           C  
ATOM    746  N   LEU A 105     -36.769 -42.372 -17.082  1.00 35.86           N  
ATOM    747  CA  LEU A 105     -37.711 -41.697 -16.209  1.00 36.28           C  
ATOM    748  C   LEU A 105     -38.764 -42.701 -15.759  1.00 36.77           C  
ATOM    749  O   LEU A 105     -39.175 -43.551 -16.548  1.00 39.77           O  
ATOM    750  CB  LEU A 105     -38.406 -40.582 -16.980  1.00 37.58           C  
ATOM    751  CG  LEU A 105     -37.632 -39.286 -17.184  1.00 35.52           C  
ATOM    752  CD1 LEU A 105     -38.214 -38.547 -18.367  1.00 37.37           C  
ATOM    753  CD2 LEU A 105     -37.650 -38.428 -15.920  1.00 35.33           C  
ATOM    754  N   LEU A 106     -39.192 -42.598 -14.502  1.00 35.45           N  
ATOM    755  CA  LEU A 106     -40.343 -43.344 -14.012  1.00 36.26           C  
ATOM    756  C   LEU A 106     -41.462 -42.355 -13.726  1.00 41.24           C  
ATOM    757  O   LEU A 106     -41.289 -41.425 -12.937  1.00 41.00           O  
ATOM    758  CB  LEU A 106     -39.992 -44.123 -12.742  1.00 36.41           C  
ATOM    759  CG  LEU A 106     -38.914 -45.216 -12.872  1.00 37.14           C  
ATOM    760  CD1 LEU A 106     -38.726 -45.920 -11.533  1.00 37.29           C  
ATOM    761  CD2 LEU A 106     -39.273 -46.212 -13.991  1.00 36.76           C  
ATOM    762  N   LYS A 107     -42.592 -42.538 -14.402  1.00 40.66           N  
ATOM    763  CA  LYS A 107     -43.800 -41.789 -14.092  1.00 43.85           C  
ATOM    764  C   LYS A 107     -44.565 -42.545 -12.997  1.00 39.74           C  
ATOM    765  O   LYS A 107     -45.019 -43.681 -13.201  1.00 39.25           O  
ATOM    766  CB  LYS A 107     -44.662 -41.640 -15.346  1.00 47.11           C  
ATOM    767  CG  LYS A 107     -45.786 -40.607 -15.273  1.00 51.72           C  
ATOM    768  CD  LYS A 107     -46.611 -40.645 -16.562  1.00 56.69           C  
ATOM    769  CE  LYS A 107     -47.080 -39.265 -17.012  1.00 63.08           C  
ATOM    770  NZ  LYS A 107     -47.988 -38.609 -16.020  1.00 64.23           N  
ATOM    771  N   LEU A 108     -44.709 -41.899 -11.850  1.00 33.96           N  
ATOM    772  CA  LEU A 108     -45.361 -42.493 -10.708  1.00 37.28           C  
ATOM    773  C   LEU A 108     -46.878 -42.459 -10.892  1.00 37.37           C  
ATOM    774  O   LEU A 108     -47.406 -41.570 -11.558  1.00 37.08           O  
ATOM    775  CB  LEU A 108     -44.941 -41.762  -9.417  1.00 38.90           C  
ATOM    776  CG  LEU A 108     -43.433 -41.737  -9.110  1.00 40.04           C  
ATOM    777  CD1 LEU A 108     -43.128 -40.998  -7.811  1.00 40.23           C  
ATOM    778  CD2 LEU A 108     -42.852 -43.137  -9.026  1.00 41.82           C  
ATOM    779  N   GLU A 109     -47.564 -43.445 -10.325  1.00 38.88           N  
ATOM    780  CA  GLU A 109     -49.025 -43.534 -10.399  1.00 38.74           C  
ATOM    781  C   GLU A 109     -49.724 -42.416  -9.601  1.00 40.08           C  
ATOM    782  O   GLU A 109     -50.816 -42.006  -9.941  1.00 42.23           O  
ATOM    783  CB  GLU A 109     -49.513 -44.903  -9.914  1.00 39.55           C  
ATOM    784  CG  GLU A 109     -49.127 -46.031 -10.859  1.00 46.27           C  
ATOM    785  CD  GLU A 109     -49.707 -47.391 -10.481  1.00 48.61           C  
ATOM    786  OE1 GLU A 109     -49.757 -47.734  -9.281  1.00 52.51           O  
ATOM    787  OE2 GLU A 109     -50.083 -48.141 -11.399  1.00 54.12           O  
ATOM    788  N   THR A 110     -49.098 -41.970  -8.523  1.00 39.83           N  
ATOM    789  CA  THR A 110     -49.594 -40.877  -7.711  1.00 42.48           C  
ATOM    790  C   THR A 110     -48.464 -39.870  -7.570  1.00 44.94           C  
ATOM    791  O   THR A 110     -47.328 -40.141  -7.998  1.00 42.52           O  
ATOM    792  CB  THR A 110     -50.065 -41.373  -6.332  1.00 42.99           C  
ATOM    793  OG1 THR A 110     -48.995 -42.045  -5.655  1.00 43.85           O  
ATOM    794  CG2 THR A 110     -51.257 -42.326  -6.483  1.00 41.89           C  
ATOM    795  N   THR A 111     -48.760 -38.717  -6.986  1.00 41.88           N  
ATOM    796  CA  THR A 111     -47.756 -37.668  -6.852  1.00 44.45           C  
ATOM    797  C   THR A 111     -47.156 -37.667  -5.445  1.00 40.44           C  
ATOM    798  O   THR A 111     -47.815 -37.991  -4.447  1.00 34.67           O  
ATOM    799  CB  THR A 111     -48.312 -36.273  -7.208  1.00 48.33           C  
ATOM    800  OG1 THR A 111     -49.311 -35.898  -6.269  1.00 44.74           O  
ATOM    801  CG2 THR A 111     -48.929 -36.264  -8.603  1.00 48.25           C  
ATOM    802  N   VAL A 112     -45.881 -37.312  -5.394  1.00 38.37           N  
ATOM    803  CA  VAL A 112     -45.140 -37.230  -4.154  1.00 38.98           C  
ATOM    804  C   VAL A 112     -45.521 -35.915  -3.476  1.00 39.38           C  
ATOM    805  O   VAL A 112     -45.497 -34.864  -4.107  1.00 37.40           O  
ATOM    806  CB  VAL A 112     -43.632 -37.217  -4.428  1.00 38.13           C  
ATOM    807  CG1 VAL A 112     -42.867 -37.023  -3.139  1.00 38.48           C  
ATOM    808  CG2 VAL A 112     -43.192 -38.497  -5.128  1.00 38.50           C  
ATOM    809  N   ASN A 113     -45.881 -35.996  -2.204  1.00 41.64           N  
ATOM    810  CA  ASN A 113     -46.063 -34.800  -1.358  1.00 41.00           C  
ATOM    811  C   ASN A 113     -44.729 -34.375  -0.832  1.00 35.82           C  
ATOM    812  O   ASN A 113     -44.170 -35.069   0.001  1.00 35.45           O  
ATOM    813  CB  ASN A 113     -46.956 -35.103  -0.147  1.00 42.03           C  
ATOM    814  CG  ASN A 113     -48.370 -35.469  -0.539  1.00 48.67           C  
ATOM    815  OD1 ASN A 113     -48.849 -35.093  -1.600  1.00 50.43           O  
ATOM    816  ND2 ASN A 113     -49.054 -36.208   0.330  1.00 51.27           N  
ATOM    817  N   TYR A 114     -44.220 -33.239  -1.278  1.00 37.40           N  
ATOM    818  CA  TYR A 114     -42.889 -32.828  -0.826  1.00 38.13           C  
ATOM    819  C   TYR A 114     -42.836 -32.540   0.670  1.00 39.29           C  
ATOM    820  O   TYR A 114     -43.751 -31.977   1.225  1.00 38.14           O  
ATOM    821  CB  TYR A 114     -42.400 -31.616  -1.603  1.00 37.45           C  
ATOM    822  CG  TYR A 114     -42.179 -31.868  -3.081  1.00 41.56           C  
ATOM    823  CD1 TYR A 114     -41.867 -33.149  -3.567  1.00 40.41           C  
ATOM    824  CD2 TYR A 114     -42.228 -30.808  -3.996  1.00 40.23           C  
ATOM    825  CE1 TYR A 114     -41.636 -33.360  -4.912  1.00 41.16           C  
ATOM    826  CE2 TYR A 114     -42.004 -31.022  -5.344  1.00 40.16           C  
ATOM    827  CZ  TYR A 114     -41.705 -32.298  -5.789  1.00 40.59           C  
ATOM    828  OH  TYR A 114     -41.493 -32.516  -7.118  1.00 42.27           O  
ATOM    829  N   ALA A 115     -41.734 -32.914   1.292  1.00 38.95           N  
ATOM    830  CA  ALA A 115     -41.521 -32.733   2.716  1.00 39.06           C  
ATOM    831  C   ALA A 115     -40.014 -32.769   2.944  1.00 38.36           C  
ATOM    832  O   ALA A 115     -39.257 -33.016   2.008  1.00 38.04           O  
ATOM    833  CB  ALA A 115     -42.227 -33.829   3.513  1.00 38.48           C  
ATOM    834  N   ASP A 116     -39.585 -32.533   4.180  1.00 38.34           N  
ATOM    835  CA  ASP A 116     -38.153 -32.553   4.521  1.00 39.33           C  
ATOM    836  C   ASP A 116     -37.475 -33.906   4.251  1.00 39.95           C  
ATOM    837  O   ASP A 116     -36.278 -33.951   4.057  1.00 34.42           O  
ATOM    838  CB  ASP A 116     -37.928 -32.148   5.985  1.00 41.10           C  
ATOM    839  CG  ASP A 116     -38.252 -30.658   6.260  1.00 45.76           C  
ATOM    840  OD1 ASP A 116     -37.551 -29.798   5.690  1.00 42.37           O  
ATOM    841  OD2 ASP A 116     -39.188 -30.358   7.059  1.00 43.66           O  
ATOM    842  N   SER A 117     -38.247 -34.991   4.275  1.00 41.51           N  
ATOM    843  CA  SER A 117     -37.740 -36.341   4.022  1.00 40.83           C  
ATOM    844  C   SER A 117     -37.830 -36.794   2.555  1.00 39.61           C  
ATOM    845  O   SER A 117     -37.300 -37.849   2.202  1.00 38.51           O  
ATOM    846  CB  SER A 117     -38.537 -37.324   4.855  1.00 38.31           C  
ATOM    847  OG  SER A 117     -39.836 -37.411   4.327  1.00 39.18           O  
ATOM    848  N   GLN A 118     -38.540 -36.036   1.723  1.00 38.42           N  
ATOM    849  CA  GLN A 118     -38.669 -36.348   0.296  1.00 35.59           C  
ATOM    850  C   GLN A 118     -38.944 -35.094  -0.526  1.00 35.22           C  
ATOM    851  O   GLN A 118     -40.010 -34.515  -0.444  1.00 37.76           O  
ATOM    852  CB  GLN A 118     -39.783 -37.391   0.063  1.00 38.50           C  
ATOM    853  CG  GLN A 118     -41.089 -37.080   0.780  1.00 37.98           C  
ATOM    854  CD  GLN A 118     -42.041 -38.245   0.856  1.00 41.27           C  
ATOM    855  OE1 GLN A 118     -41.639 -39.385   1.098  1.00 45.25           O  
ATOM    856  NE2 GLN A 118     -43.312 -37.975   0.647  1.00 41.71           N  
ATOM    857  N   ARG A 119     -37.992 -34.682  -1.349  1.00 37.91           N  
ATOM    858  CA  ARG A 119     -38.169 -33.493  -2.168  1.00 35.77           C  
ATOM    859  C   ARG A 119     -37.241 -33.550  -3.375  1.00 38.05           C  
ATOM    860  O   ARG A 119     -36.233 -34.264  -3.319  1.00 33.41           O  
ATOM    861  CB  ARG A 119     -37.921 -32.238  -1.325  1.00 35.89           C  
ATOM    862  CG  ARG A 119     -36.535 -32.047  -0.720  1.00 38.70           C  
ATOM    863  CD  ARG A 119     -35.539 -31.423  -1.685  1.00 43.91           C  
ATOM    864  NE  ARG A 119     -34.450 -30.717  -1.007  1.00 50.00           N  
ATOM    865  CZ  ARG A 119     -33.410 -30.176  -1.640  1.00 55.79           C  
ATOM    866  NH1 ARG A 119     -33.312 -30.256  -2.971  1.00 57.41           N  
ATOM    867  NH2 ARG A 119     -32.455 -29.556  -0.948  1.00 56.62           N  
ATOM    868  N   PRO A 121     -37.540 -32.764  -4.436  1.00 33.92           N  
ATOM    869  CA  PRO A 121     -36.827 -32.908  -5.687  1.00 36.70           C  
ATOM    870  C   PRO A 121     -35.460 -32.207  -5.644  1.00 41.76           C  
ATOM    871  O   PRO A 121     -35.260 -31.288  -4.861  1.00 38.92           O  
ATOM    872  CB  PRO A 121     -37.756 -32.231  -6.701  1.00 37.42           C  
ATOM    873  CG  PRO A 121     -38.473 -31.161  -5.905  1.00 36.31           C  
ATOM    874  CD  PRO A 121     -38.410 -31.573  -4.446  1.00 35.91           C  
ATOM    875  N   ILE A 122     -34.530 -32.714  -6.449  1.00 44.40           N  
ATOM    876  CA  ILE A 122     -33.233 -32.090  -6.692  1.00 43.20           C  
ATOM    877  C   ILE A 122     -33.320 -31.327  -8.008  1.00 40.82           C  
ATOM    878  O   ILE A 122     -34.043 -31.720  -8.936  1.00 39.26           O  
ATOM    879  CB  ILE A 122     -32.062 -33.110  -6.690  1.00 44.76           C  
ATOM    880  CG1 ILE A 122     -30.731 -32.422  -7.035  1.00 45.71           C  
ATOM    881  CG2 ILE A 122     -32.321 -34.260  -7.657  1.00 43.82           C  
ATOM    882  CD1 ILE A 122     -29.503 -33.250  -6.718  1.00 44.86           C  
ATOM    883  N   SER A 123     -32.630 -30.191  -8.051  1.00 41.13           N  
ATOM    884  CA  SER A 123     -32.618 -29.330  -9.228  1.00 39.32           C  
ATOM    885  C   SER A 123     -31.712 -29.910 -10.298  1.00 37.47           C  
ATOM    886  O   SER A 123     -30.683 -30.496  -9.998  1.00 39.74           O  
ATOM    887  CB  SER A 123     -32.118 -27.921  -8.866  1.00 42.56           C  
ATOM    888  OG  SER A 123     -33.133 -27.206  -8.179  1.00 47.48           O  
ATOM    889  N   LEU A 124     -32.111 -29.744 -11.545  1.00 38.65           N  
ATOM    890  CA  LEU A 124     -31.294 -30.167 -12.659  1.00 41.39           C  
ATOM    891  C   LEU A 124     -30.280 -29.082 -12.969  1.00 40.00           C  
ATOM    892  O   LEU A 124     -30.562 -27.906 -12.771  1.00 37.70           O  
ATOM    893  CB  LEU A 124     -32.175 -30.425 -13.869  1.00 41.37           C  
ATOM    894  CG  LEU A 124     -33.197 -31.530 -13.628  1.00 41.64           C  
ATOM    895  CD1 LEU A 124     -34.167 -31.544 -14.787  1.00 41.02           C  
ATOM    896  CD2 LEU A 124     -32.527 -32.885 -13.443  1.00 41.95           C  
ATOM    897  N   PRO A 125     -29.090 -29.465 -13.443  1.00 42.49           N  
ATOM    898  CA  PRO A 125     -28.170 -28.399 -13.833  1.00 46.15           C  
ATOM    899  C   PRO A 125     -28.667 -27.708 -15.093  1.00 42.82           C  
ATOM    900  O   PRO A 125     -29.451 -28.276 -15.838  1.00 41.49           O  
ATOM    901  CB  PRO A 125     -26.847 -29.132 -14.100  1.00 44.67           C  
ATOM    902  CG  PRO A 125     -27.166 -30.595 -14.150  1.00 44.38           C  
ATOM    903  CD  PRO A 125     -28.646 -30.775 -13.946  1.00 43.98           C  
ATOM    904  N   SER A 126     -28.193 -26.495 -15.313  1.00 42.86           N  
ATOM    905  CA  SER A 126     -28.678 -25.671 -16.402  1.00 42.10           C  
ATOM    906  C   SER A 126     -27.624 -25.659 -17.494  1.00 40.07           C  
ATOM    907  O   SER A 126     -26.429 -25.770 -17.198  1.00 36.81           O  
ATOM    908  CB  SER A 126     -28.963 -24.272 -15.862  1.00 43.50           C  
ATOM    909  OG  SER A 126     -28.342 -23.284 -16.645  1.00 46.56           O  
ATOM    910  N   LYS A 127     -28.055 -25.517 -18.746  1.00 40.82           N  
ATOM    911  CA  LYS A 127     -27.132 -25.539 -19.887  1.00 42.75           C  
ATOM    912  C   LYS A 127     -25.998 -24.512 -19.751  1.00 45.97           C  
ATOM    913  O   LYS A 127     -24.888 -24.741 -20.235  1.00 45.84           O  
ATOM    914  CB  LYS A 127     -27.868 -25.301 -21.205  1.00 45.26           C  
ATOM    915  CG  LYS A 127     -28.428 -26.554 -21.860  1.00 47.86           C  
ATOM    916  CD  LYS A 127     -29.350 -26.187 -23.008  1.00 49.66           C  
ATOM    917  CE  LYS A 127     -29.848 -27.400 -23.770  1.00 52.04           C  
ATOM    918  NZ  LYS A 127     -30.917 -27.009 -24.737  1.00 51.16           N  
ATOM    919  N   GLY A 128     -26.274 -23.401 -19.074  1.00 46.06           N  
ATOM    920  CA  GLY A 128     -25.298 -22.336 -18.889  1.00 49.55           C  
ATOM    921  C   GLY A 128     -24.269 -22.614 -17.810  1.00 51.26           C  
ATOM    922  O   GLY A 128     -23.458 -21.756 -17.506  1.00 53.66           O  
ATOM    923  N   ASP A 129     -24.249 -23.958 -17.124  1.00 53.75           N  
ATOM    924  CA  ASP A 129     -23.375 -24.352 -16.050  1.00 53.28           C  
ATOM    925  C   ASP A 129     -22.380 -25.345 -16.619  1.00 52.20           C  
ATOM    926  O   ASP A 129     -21.830 -26.128 -15.907  1.00 47.94           O  
ATOM    927  CB  ASP A 129     -24.155 -25.110 -14.977  1.00 20.00           C  
ATOM    928  CG  ASP A 129     -25.050 -24.252 -14.126  1.00 20.00           C  
ATOM    929  OD1 ASP A 129     -24.858 -23.039 -14.072  1.00 20.00           O  
ATOM    930  OD2 ASP A 129     -25.951 -24.834 -13.484  1.00 20.00           O  
ATOM    931  N   ARG A 130     -22.206 -25.425 -18.019  1.00 55.57           N  
ATOM    932  CA  ARG A 130     -21.363 -26.473 -18.604  1.00 55.75           C  
ATOM    933  C   ARG A 130     -19.892 -26.286 -18.261  1.00 55.81           C  
ATOM    934  O   ARG A 130     -19.094 -27.201 -18.421  1.00 55.52           O  
ATOM    935  CB  ARG A 130     -21.535 -26.513 -20.124  1.00 54.00           C  
ATOM    936  CG  ARG A 130     -22.774 -27.254 -20.565  1.00 55.44           C  
ATOM    937  CD  ARG A 130     -22.804 -27.399 -22.059  1.00 57.22           C  
ATOM    938  NE  ARG A 130     -23.889 -28.277 -22.505  1.00 60.04           N  
ATOM    939  CZ  ARG A 130     -24.860 -27.906 -23.335  1.00 60.19           C  
ATOM    940  NH1 ARG A 130     -24.891 -26.681 -23.823  1.00 60.32           N  
ATOM    941  NH2 ARG A 130     -25.797 -28.763 -23.696  1.00 64.73           N  
ATOM    942  N   ASN A 131     -19.555 -25.087 -17.808  1.00 56.55           N  
ATOM    943  CA  ASN A 131     -18.182 -24.711 -17.479  1.00 61.91           C  
ATOM    944  C   ASN A 131     -17.990 -24.495 -15.983  1.00 58.17           C  
ATOM    945  O   ASN A 131     -16.927 -24.068 -15.545  1.00 64.21           O  
ATOM    946  CB  ASN A 131     -17.802 -23.434 -18.232  1.00 68.93           C  
ATOM    947  CG  ASN A 131     -18.816 -22.320 -18.038  1.00 76.02           C  
ATOM    948  OD1 ASN A 131     -19.841 -22.490 -17.364  1.00 76.69           O  
ATOM    949  ND2 ASN A 131     -18.543 -21.177 -18.638  1.00 81.67           N  
ATOM    950  N   VAL A 132     -19.025 -24.782 -15.200  1.00 58.78           N  
ATOM    951  CA  VAL A 132     -18.927 -24.724 -13.750  1.00 56.44           C  
ATOM    952  C   VAL A 132     -17.938 -25.817 -13.305  1.00 55.37           C  
ATOM    953  O   VAL A 132     -17.869 -26.879 -13.917  1.00 53.50           O  
ATOM    954  CB  VAL A 132     -20.305 -24.902 -13.071  1.00 55.31           C  
ATOM    955  CG1 VAL A 132     -20.161 -25.085 -11.571  1.00 54.15           C  
ATOM    956  CG2 VAL A 132     -21.209 -23.708 -13.369  1.00 55.38           C  
ATOM    957  N   ILE A 132A    -17.160 -25.499 -12.269  1.00 54.74           N  
ATOM    958  CA  ILE A 132A    -16.176 -26.396 -11.657  1.00 53.61           C  
ATOM    959  C   ILE A 132A    -16.740 -26.874 -10.310  1.00 49.38           C  
ATOM    960  O   ILE A 132A    -16.667 -26.163  -9.301  1.00 46.36           O  
ATOM    961  CB  ILE A 132A    -14.816 -25.668 -11.464  1.00 57.49           C  
ATOM    962  CG1 ILE A 132A    -14.148 -25.406 -12.829  1.00 57.56           C  
ATOM    963  CG2 ILE A 132A    -13.867 -26.460 -10.551  1.00 57.63           C  
ATOM    964  CD1 ILE A 132A    -13.503 -26.626 -13.474  1.00 60.23           C  
ATOM    965  N   TYR A 133     -17.335 -28.069 -10.308  1.00 48.88           N  
ATOM    966  CA  TYR A 133     -17.955 -28.614  -9.093  1.00 45.54           C  
ATOM    967  C   TYR A 133     -16.862 -29.172  -8.210  1.00 43.95           C  
ATOM    968  O   TYR A 133     -16.052 -29.965  -8.646  1.00 46.33           O  
ATOM    969  CB  TYR A 133     -18.987 -29.708  -9.397  1.00 43.78           C  
ATOM    970  CG  TYR A 133     -20.191 -29.246 -10.190  1.00 41.47           C  
ATOM    971  CD1 TYR A 133     -21.287 -28.679  -9.562  1.00 44.72           C  
ATOM    972  CD2 TYR A 133     -20.239 -29.393 -11.570  1.00 44.23           C  
ATOM    973  CE1 TYR A 133     -22.396 -28.251 -10.291  1.00 43.28           C  
ATOM    974  CE2 TYR A 133     -21.338 -28.969 -12.313  1.00 42.69           C  
ATOM    975  CZ  TYR A 133     -22.420 -28.402 -11.668  1.00 44.06           C  
ATOM    976  OH  TYR A 133     -23.523 -27.988 -12.397  1.00 44.15           O  
ATOM    977  N   THR A 134     -16.850 -28.739  -6.962  1.00 43.01           N  
ATOM    978  CA  THR A 134     -15.865 -29.166  -6.010  1.00 42.18           C  
ATOM    979  C   THR A 134     -16.489 -29.881  -4.821  1.00 43.78           C  
ATOM    980  O   THR A 134     -15.746 -30.319  -3.936  1.00 44.79           O  
ATOM    981  CB  THR A 134     -15.107 -27.944  -5.457  1.00 44.25           C  
ATOM    982  OG1 THR A 134     -16.059 -27.045  -4.865  1.00 45.56           O  
ATOM    983  CG2 THR A 134     -14.359 -27.232  -6.568  1.00 44.55           C  
ATOM    984  N   ASP A 135     -17.821 -30.012  -4.775  1.00 43.44           N  
ATOM    985  CA  ASP A 135     -18.466 -30.636  -3.612  1.00 46.09           C  
ATOM    986  C   ASP A 135     -19.540 -31.680  -4.023  1.00 46.40           C  
ATOM    987  O   ASP A 135     -20.745 -31.453  -3.866  1.00 46.18           O  
ATOM    988  CB  ASP A 135     -19.043 -29.554  -2.693  1.00 48.96           C  
ATOM    989  CG  ASP A 135     -19.366 -30.076  -1.283  1.00 51.92           C  
ATOM    990  OD1 ASP A 135     -18.853 -31.148  -0.876  1.00 52.06           O  
ATOM    991  OD2 ASP A 135     -20.149 -29.408  -0.579  1.00 54.57           O  
ATOM    992  N   CYS A 136     -19.050 -32.831  -4.512  1.00 46.17           N  
ATOM    993  CA  CYS A 136     -19.852 -33.861  -5.201  1.00 43.86           C  
ATOM    994  C   CYS A 136     -19.874 -35.149  -4.406  1.00 41.64           C  
ATOM    995  O   CYS A 136     -18.847 -35.559  -3.869  1.00 38.42           O  
ATOM    996  CB  CYS A 136     -19.272 -34.160  -6.588  1.00 43.30           C  
ATOM    997  SG  CYS A 136     -19.376 -32.821  -7.770  1.00 43.79           S  
ATOM    998  N   TRP A 137     -21.044 -35.786  -4.328  1.00 39.25           N  
ATOM    999  CA  TRP A 137     -21.203 -36.973  -3.486  1.00 39.17           C  
ATOM   1000  C   TRP A 137     -21.983 -38.063  -4.200  1.00 38.47           C  
ATOM   1001  O   TRP A 137     -22.928 -37.775  -4.932  1.00 36.03           O  
ATOM   1002  CB  TRP A 137     -21.919 -36.623  -2.171  1.00 40.18           C  
ATOM   1003  CG  TRP A 137     -21.172 -35.671  -1.294  1.00 40.56           C  
ATOM   1004  CD1 TRP A 137     -20.952 -34.335  -1.524  1.00 39.34           C  
ATOM   1005  CD2 TRP A 137     -20.550 -35.968  -0.041  1.00 39.75           C  
ATOM   1006  NE1 TRP A 137     -20.235 -33.798  -0.493  1.00 40.43           N  
ATOM   1007  CE2 TRP A 137     -19.968 -34.775   0.427  1.00 38.68           C  
ATOM   1008  CE3 TRP A 137     -20.414 -37.125   0.721  1.00 38.42           C  
ATOM   1009  CZ2 TRP A 137     -19.284 -34.703   1.632  1.00 40.25           C  
ATOM   1010  CZ3 TRP A 137     -19.721 -37.054   1.933  1.00 40.74           C  
ATOM   1011  CH2 TRP A 137     -19.174 -35.853   2.376  1.00 40.16           C  
ATOM   1012  N   VAL A 138     -21.579 -39.311  -3.967  1.00 36.06           N  
ATOM   1013  CA  VAL A 138     -22.295 -40.452  -4.514  1.00 34.71           C  
ATOM   1014  C   VAL A 138     -22.932 -41.203  -3.350  1.00 32.31           C  
ATOM   1015  O   VAL A 138     -22.316 -41.352  -2.295  1.00 38.66           O  
ATOM   1016  CB  VAL A 138     -21.374 -41.366  -5.379  1.00 34.86           C  
ATOM   1017  CG1 VAL A 138     -20.262 -42.035  -4.566  1.00 33.17           C  
ATOM   1018  CG2 VAL A 138     -22.215 -42.398  -6.127  1.00 37.78           C  
ATOM   1019  N   THR A 139     -24.167 -41.657  -3.536  1.00 31.74           N  
ATOM   1020  CA  THR A 139     -24.959 -42.224  -2.456  1.00 30.14           C  
ATOM   1021  C   THR A 139     -25.683 -43.462  -2.924  1.00 28.39           C  
ATOM   1022  O   THR A 139     -26.069 -43.536  -4.066  1.00 26.65           O  
ATOM   1023  CB  THR A 139     -26.044 -41.230  -1.968  1.00 30.30           C  
ATOM   1024  OG1 THR A 139     -26.750 -40.707  -3.086  1.00 30.56           O  
ATOM   1025  CG2 THR A 139     -25.423 -40.058  -1.221  1.00 32.55           C  
ATOM   1026  N   GLY A 140     -25.900 -44.414  -2.017  1.00 28.21           N  
ATOM   1027  CA  GLY A 140     -26.775 -45.561  -2.306  1.00 28.65           C  
ATOM   1028  C   GLY A 140     -26.649 -46.678  -1.297  1.00 30.08           C  
ATOM   1029  O   GLY A 140     -25.893 -46.582  -0.309  1.00 28.12           O  
ATOM   1030  N   TRP A 141     -27.446 -47.718  -1.515  1.00 29.87           N  
ATOM   1031  CA  TRP A 141     -27.439 -48.901  -0.669  1.00 31.39           C  
ATOM   1032  C   TRP A 141     -26.635 -50.050  -1.265  1.00 31.73           C  
ATOM   1033  O   TRP A 141     -26.750 -51.171  -0.790  1.00 30.67           O  
ATOM   1034  CB  TRP A 141     -28.865 -49.398  -0.424  1.00 32.27           C  
ATOM   1035  CG  TRP A 141     -29.713 -48.453   0.363  1.00 32.22           C  
ATOM   1036  CD1 TRP A 141     -29.863 -48.427   1.733  1.00 32.06           C  
ATOM   1037  CD2 TRP A 141     -30.512 -47.392  -0.147  1.00 31.10           C  
ATOM   1038  NE1 TRP A 141     -30.710 -47.422   2.093  1.00 31.82           N  
ATOM   1039  CE2 TRP A 141     -31.130 -46.765   0.963  1.00 31.75           C  
ATOM   1040  CE3 TRP A 141     -30.752 -46.892  -1.420  1.00 31.02           C  
ATOM   1041  CZ2 TRP A 141     -31.985 -45.677   0.824  1.00 30.97           C  
ATOM   1042  CZ3 TRP A 141     -31.614 -45.820  -1.559  1.00 32.68           C  
ATOM   1043  CH2 TRP A 141     -32.227 -45.228  -0.444  1.00 32.36           C  
ATOM   1044  N   GLY A 142     -25.797 -49.767  -2.260  1.00 33.91           N  
ATOM   1045  CA  GLY A 142     -24.968 -50.812  -2.920  1.00 33.90           C  
ATOM   1046  C   GLY A 142     -23.911 -51.486  -2.080  1.00 32.90           C  
ATOM   1047  O   GLY A 142     -23.753 -51.188  -0.907  1.00 31.90           O  
ATOM   1048  N   TYR A 143     -23.165 -52.401  -2.704  1.00 33.77           N  
ATOM   1049  CA  TYR A 143     -22.106 -53.150  -2.042  1.00 34.55           C  
ATOM   1050  C   TYR A 143     -20.976 -52.228  -1.555  1.00 36.53           C  
ATOM   1051  O   TYR A 143     -20.736 -51.168  -2.123  1.00 36.05           O  
ATOM   1052  CB  TYR A 143     -21.487 -54.172  -2.997  1.00 36.50           C  
ATOM   1053  CG  TYR A 143     -22.351 -55.314  -3.478  1.00 35.46           C  
ATOM   1054  CD1 TYR A 143     -23.723 -55.358  -3.226  1.00 36.98           C  
ATOM   1055  CD2 TYR A 143     -21.795 -56.336  -4.245  1.00 36.48           C  
ATOM   1056  CE1 TYR A 143     -24.499 -56.398  -3.696  1.00 38.14           C  
ATOM   1057  CE2 TYR A 143     -22.570 -57.393  -4.708  1.00 39.71           C  
ATOM   1058  CZ  TYR A 143     -23.921 -57.409  -4.444  1.00 38.11           C  
ATOM   1059  OH  TYR A 143     -24.694 -58.443  -4.904  1.00 39.79           O  
ATOM   1060  N   ARG A 144     -20.309 -52.644  -0.481  1.00 41.06           N  
ATOM   1061  CA  ARG A 144     -19.138 -51.918   0.056  1.00 44.59           C  
ATOM   1062  C   ARG A 144     -17.847 -52.437  -0.554  1.00 43.89           C  
ATOM   1063  O   ARG A 144     -16.791 -51.854  -0.346  1.00 45.45           O  
ATOM   1064  CB  ARG A 144     -19.051 -52.045   1.569  1.00 47.79           C  
ATOM   1065  CG  ARG A 144     -20.317 -51.713   2.315  1.00 52.48           C  
ATOM   1066  CD  ARG A 144     -20.114 -51.815   3.831  1.00 62.14           C  
ATOM   1067  NE  ARG A 144     -20.076 -50.501   4.477  1.00 67.09           N  
ATOM   1068  CZ  ARG A 144     -20.010 -50.286   5.796  1.00 74.78           C  
ATOM   1069  NH1 ARG A 144     -19.967 -51.304   6.660  1.00 74.68           N  
ATOM   1070  NH2 ARG A 144     -19.985 -49.033   6.255  1.00 73.30           N  
ATOM   1071  N   LYS A 145     -17.951 -53.553  -1.278  1.00 47.73           N  
ATOM   1072  CA  LYS A 145     -16.924 -54.022  -2.209  1.00 49.55           C  
ATOM   1073  C   LYS A 145     -17.549 -54.954  -3.244  1.00 47.88           C  
ATOM   1074  O   LYS A 145     -18.698 -55.381  -3.095  1.00 44.26           O  
ATOM   1075  CB  LYS A 145     -15.802 -54.743  -1.469  1.00 55.78           C  
ATOM   1076  CG  LYS A 145     -16.218 -56.032  -0.778  1.00 60.05           C  
ATOM   1077  CD  LYS A 145     -15.005 -56.759  -0.208  1.00 67.08           C  
ATOM   1078  CE  LYS A 145     -15.322 -58.208   0.158  1.00 70.18           C  
ATOM   1079  NZ  LYS A 145     -14.242 -58.803   1.000  1.00 73.22           N  
ATOM   1080  N   LEU A 146     -16.773 -55.311  -4.261  1.00 48.08           N  
ATOM   1081  CA  LEU A 146     -17.290 -56.029  -5.432  1.00 52.41           C  
ATOM   1082  C   LEU A 146     -18.077 -57.288  -5.075  1.00 51.10           C  
ATOM   1083  O   LEU A 146     -19.009 -57.672  -5.776  1.00 49.92           O  
ATOM   1084  CB  LEU A 146     -16.156 -56.411  -6.398  1.00 55.68           C  
ATOM   1085  CG  LEU A 146     -16.327 -56.021  -7.868  1.00 57.36           C  
ATOM   1086  CD1 LEU A 146     -15.251 -56.689  -8.714  1.00 61.39           C  
ATOM   1087  CD2 LEU A 146     -17.697 -56.377  -8.405  1.00 60.02           C  
ATOM   1088  N   ARG A 147     -17.679 -57.938  -3.994  1.00 48.81           N  
ATOM   1089  CA  ARG A 147     -18.350 -59.147  -3.542  1.00 51.79           C  
ATOM   1090  C   ARG A 147     -18.830 -58.858  -2.143  1.00 47.06           C  
ATOM   1091  O   ARG A 147     -18.037 -58.857  -1.194  1.00 47.12           O  
ATOM   1092  CB  ARG A 147     -17.381 -60.342  -3.551  1.00 60.10           C  
ATOM   1093  CG  ARG A 147     -18.071 -61.705  -3.537  1.00 69.26           C  
ATOM   1094  CD  ARG A 147     -17.421 -62.696  -4.505  1.00 77.87           C  
ATOM   1095  NE  ARG A 147     -18.415 -63.539  -5.197  1.00 88.13           N  
ATOM   1096  CZ  ARG A 147     -18.565 -63.647  -6.526  1.00 87.33           C  
ATOM   1097  NH1 ARG A 147     -17.773 -62.991  -7.374  1.00 85.28           N  
ATOM   1098  NH2 ARG A 147     -19.515 -64.437  -7.018  1.00 82.11           N  
ATOM   1099  N   ASP A 148     -20.125 -58.571  -2.026  1.00 43.12           N  
ATOM   1100  CA  ASP A 148     -20.722 -58.150  -0.773  1.00 37.90           C  
ATOM   1101  C   ASP A 148     -22.253 -58.336  -0.858  1.00 37.34           C  
ATOM   1102  O   ASP A 148     -22.750 -59.255  -1.535  1.00 34.04           O  
ATOM   1103  CB  ASP A 148     -20.314 -56.694  -0.515  1.00 38.76           C  
ATOM   1104  CG  ASP A 148     -20.504 -56.257   0.935  1.00 40.88           C  
ATOM   1105  OD1 ASP A 148     -20.425 -57.103   1.835  1.00 38.11           O  
ATOM   1106  OD2 ASP A 148     -20.738 -55.047   1.158  1.00 43.58           O  
ATOM   1107  N   LYS A 149     -22.990 -57.464  -0.182  1.00 36.85           N  
ATOM   1108  CA  LYS A 149     -24.430 -57.443  -0.215  1.00 37.69           C  
ATOM   1109  C   LYS A 149     -24.952 -56.016  -0.070  1.00 36.20           C  
ATOM   1110  O   LYS A 149     -24.218 -55.113   0.317  1.00 34.38           O  
ATOM   1111  CB  LYS A 149     -24.980 -58.300   0.906  1.00 40.55           C  
ATOM   1112  CG  LYS A 149     -24.561 -57.845   2.295  1.00 45.84           C  
ATOM   1113  CD  LYS A 149     -25.251 -58.695   3.349  1.00 50.87           C  
ATOM   1114  CE  LYS A 149     -24.747 -58.346   4.735  1.00 60.08           C  
ATOM   1115  NZ  LYS A 149     -25.504 -59.039   5.812  1.00 67.94           N  
ATOM   1116  N   ILE A 151     -26.235 -55.850  -0.384  1.00 36.07           N  
ATOM   1117  CA  ILE A 151     -26.952 -54.582  -0.264  1.00 36.06           C  
ATOM   1118  C   ILE A 151     -26.879 -54.108   1.181  1.00 36.50           C  
ATOM   1119  O   ILE A 151     -27.046 -54.904   2.093  1.00 37.21           O  
ATOM   1120  CB  ILE A 151     -28.421 -54.763  -0.705  1.00 34.63           C  
ATOM   1121  CG1 ILE A 151     -28.471 -54.983  -2.202  1.00 34.25           C  
ATOM   1122  CG2 ILE A 151     -29.305 -53.575  -0.324  1.00 36.76           C  
ATOM   1123  CD1 ILE A 151     -27.812 -53.898  -3.014  1.00 34.01           C  
ATOM   1124  N   GLN A 152     -26.593 -52.830   1.386  1.00 35.12           N  
ATOM   1125  CA  GLN A 152     -26.409 -52.328   2.734  1.00 36.99           C  
ATOM   1126  C   GLN A 152     -27.734 -51.848   3.286  1.00 35.44           C  
ATOM   1127  O   GLN A 152     -28.557 -51.344   2.557  1.00 37.00           O  
ATOM   1128  CB  GLN A 152     -25.374 -51.211   2.786  1.00 36.80           C  
ATOM   1129  CG  GLN A 152     -23.973 -51.659   2.422  1.00 39.58           C  
ATOM   1130  CD  GLN A 152     -23.468 -52.776   3.325  1.00 42.53           C  
ATOM   1131  OE1 GLN A 152     -23.293 -52.569   4.530  1.00 38.21           O  
ATOM   1132  NE2 GLN A 152     -23.227 -53.976   2.738  1.00 40.08           N  
ATOM   1133  N   ASN A 153     -27.934 -52.032   4.580  1.00 37.05           N  
ATOM   1134  CA  ASN A 153     -29.137 -51.530   5.248  1.00 35.80           C  
ATOM   1135  C   ASN A 153     -29.253 -50.007   5.230  1.00 32.86           C  
ATOM   1136  O   ASN A 153     -30.286 -49.471   4.854  1.00 32.55           O  
ATOM   1137  CB  ASN A 153     -29.189 -52.023   6.686  1.00 35.68           C  
ATOM   1138  CG  ASN A 153     -30.466 -51.609   7.402  1.00 34.90           C  
ATOM   1139  OD1 ASN A 153     -31.547 -51.617   6.831  1.00 37.64           O  
ATOM   1140  ND2 ASN A 153     -30.336 -51.270   8.669  1.00 36.36           N  
ATOM   1141  N   THR A 154     -28.206 -49.328   5.670  1.00 32.91           N  
ATOM   1142  CA  THR A 154     -28.193 -47.869   5.794  1.00 33.78           C  
ATOM   1143  C   THR A 154     -27.570 -47.192   4.583  1.00 33.48           C  
ATOM   1144  O   THR A 154     -26.461 -47.535   4.196  1.00 37.61           O  
ATOM   1145  CB  THR A 154     -27.398 -47.432   7.030  1.00 34.67           C  
ATOM   1146  OG1 THR A 154     -27.892 -48.140   8.162  1.00 39.61           O  
ATOM   1147  CG2 THR A 154     -27.521 -45.898   7.274  1.00 37.70           C  
ATOM   1148  N   LEU A 155     -28.296 -46.228   4.010  1.00 33.42           N  
ATOM   1149  CA  LEU A 155     -27.837 -45.426   2.881  1.00 33.42           C  
ATOM   1150  C   LEU A 155     -26.466 -44.830   3.148  1.00 35.43           C  
ATOM   1151  O   LEU A 155     -26.285 -44.090   4.130  1.00 31.73           O  
ATOM   1152  CB  LEU A 155     -28.836 -44.298   2.603  1.00 33.87           C  
ATOM   1153  CG  LEU A 155     -28.518 -43.275   1.517  1.00 34.38           C  
ATOM   1154  CD1 LEU A 155     -28.614 -43.869   0.126  1.00 35.78           C  
ATOM   1155  CD2 LEU A 155     -29.457 -42.084   1.661  1.00 36.55           C  
ATOM   1156  N   GLN A 156     -25.507 -45.153   2.275  1.00 34.51           N  
ATOM   1157  CA  GLN A 156     -24.130 -44.723   2.429  1.00 31.99           C  
ATOM   1158  C   GLN A 156     -23.845 -43.516   1.553  1.00 34.92           C  
ATOM   1159  O   GLN A 156     -24.475 -43.337   0.499  1.00 33.08           O  
ATOM   1160  CB  GLN A 156     -23.181 -45.856   2.035  1.00 33.66           C  
ATOM   1161  CG  GLN A 156     -23.309 -47.103   2.875  1.00 33.01           C  
ATOM   1162  CD  GLN A 156     -22.667 -46.956   4.235  1.00 36.85           C  
ATOM   1163  OE1 GLN A 156     -21.467 -46.753   4.354  1.00 34.38           O  
ATOM   1164  NE2 GLN A 156     -23.484 -47.046   5.280  1.00 38.24           N  
ATOM   1165  N   LYS A 157     -22.858 -42.716   1.958  1.00 32.93           N  
ATOM   1166  CA  LYS A 157     -22.417 -41.571   1.166  1.00 35.01           C  
ATOM   1167  C   LYS A 157     -20.892 -41.532   1.011  1.00 31.88           C  
ATOM   1168  O   LYS A 157     -20.162 -42.051   1.830  1.00 31.37           O  
ATOM   1169  CB  LYS A 157     -22.898 -40.243   1.797  1.00 38.55           C  
ATOM   1170  CG  LYS A 157     -22.256 -39.917   3.151  1.00 40.14           C  
ATOM   1171  CD  LYS A 157     -22.764 -38.601   3.741  1.00 39.91           C  
ATOM   1172  CE  LYS A 157     -22.163 -38.356   5.124  1.00 42.39           C  
ATOM   1173  NZ  LYS A 157     -22.889 -37.275   5.853  1.00 45.81           N  
ATOM   1174  N   ALA A 158     -20.423 -40.861  -0.032  1.00 33.84           N  
ATOM   1175  CA  ALA A 158     -18.988 -40.698  -0.236  1.00 33.83           C  
ATOM   1176  C   ALA A 158     -18.737 -39.497  -1.105  1.00 34.88           C  
ATOM   1177  O   ALA A 158     -19.411 -39.282  -2.109  1.00 35.17           O  
ATOM   1178  CB  ALA A 158     -18.362 -41.969  -0.842  1.00 35.03           C  
ATOM   1179  N   LYS A 159     -17.740 -38.715  -0.702  1.00 38.08           N  
ATOM   1180  CA  LYS A 159     -17.340 -37.537  -1.418  1.00 37.45           C  
ATOM   1181  C   LYS A 159     -16.344 -38.007  -2.454  1.00 37.53           C  
ATOM   1182  O   LYS A 159     -15.402 -38.726  -2.129  1.00 36.16           O  
ATOM   1183  CB  LYS A 159     -16.693 -36.529  -0.473  1.00 39.39           C  
ATOM   1184  CG  LYS A 159     -16.324 -35.246  -1.163  1.00 42.48           C  
ATOM   1185  CD  LYS A 159     -15.814 -34.185  -0.199  1.00 45.95           C  
ATOM   1186  CE  LYS A 159     -15.771 -32.850  -0.928  1.00 50.59           C  
ATOM   1187  NZ  LYS A 159     -15.013 -31.814  -0.183  1.00 55.59           N  
ATOM   1188  N   ILE A 160     -16.581 -37.655  -3.712  1.00 36.80           N  
ATOM   1189  CA  ILE A 160     -15.676 -38.075  -4.768  1.00 41.16           C  
ATOM   1190  C   ILE A 160     -15.427 -36.892  -5.705  1.00 37.12           C  
ATOM   1191  O   ILE A 160     -16.372 -36.206  -6.073  1.00 38.27           O  
ATOM   1192  CB  ILE A 160     -16.220 -39.319  -5.496  1.00 46.80           C  
ATOM   1193  CG1 ILE A 160     -15.886 -40.584  -4.702  1.00 52.62           C  
ATOM   1194  CG2 ILE A 160     -15.585 -39.477  -6.856  1.00 49.58           C  
ATOM   1195  CD1 ILE A 160     -16.942 -40.968  -3.699  1.00 53.64           C  
ATOM   1196  N   PRO A 161     -14.152 -36.619  -6.052  1.00 37.13           N  
ATOM   1197  CA  PRO A 161     -13.855 -35.491  -6.959  1.00 37.27           C  
ATOM   1198  C   PRO A 161     -14.135 -35.814  -8.426  1.00 36.19           C  
ATOM   1199  O   PRO A 161     -13.887 -36.937  -8.845  1.00 38.10           O  
ATOM   1200  CB  PRO A 161     -12.359 -35.285  -6.771  1.00 37.87           C  
ATOM   1201  CG  PRO A 161     -11.832 -36.635  -6.437  1.00 37.98           C  
ATOM   1202  CD  PRO A 161     -12.926 -37.352  -5.678  1.00 37.72           C  
ATOM   1203  N   LEU A 162     -14.650 -34.854  -9.187  1.00 38.87           N  
ATOM   1204  CA  LEU A 162     -14.783 -35.011 -10.631  1.00 42.65           C  
ATOM   1205  C   LEU A 162     -13.409 -35.081 -11.283  1.00 48.06           C  
ATOM   1206  O   LEU A 162     -12.460 -34.460 -10.828  1.00 52.89           O  
ATOM   1207  CB  LEU A 162     -15.568 -33.865 -11.276  1.00 43.27           C  
ATOM   1208  CG  LEU A 162     -17.028 -33.647 -10.865  1.00 42.73           C  
ATOM   1209  CD1 LEU A 162     -17.666 -32.543 -11.687  1.00 42.16           C  
ATOM   1210  CD2 LEU A 162     -17.830 -34.911 -11.042  1.00 43.70           C  
ATOM   1211  N   VAL A 163     -13.311 -35.860 -12.343  1.00 48.73           N  
ATOM   1212  CA  VAL A 163     -12.126 -35.864 -13.176  1.00 50.52           C  
ATOM   1213  C   VAL A 163     -12.584 -35.459 -14.563  1.00 47.36           C  
ATOM   1214  O   VAL A 163     -13.706 -35.724 -14.944  1.00 47.96           O  
ATOM   1215  CB  VAL A 163     -11.404 -37.237 -13.206  1.00 50.13           C  
ATOM   1216  CG1 VAL A 163     -11.187 -37.766 -11.796  1.00 53.36           C  
ATOM   1217  CG2 VAL A 163     -12.152 -38.260 -14.034  1.00 51.47           C  
ATOM   1218  N   THR A 164     -11.703 -34.807 -15.305  1.00 44.38           N  
ATOM   1219  CA  THR A 164     -12.013 -34.377 -16.654  1.00 43.84           C  
ATOM   1220  C   THR A 164     -12.215 -35.594 -17.571  1.00 43.69           C  
ATOM   1221  O   THR A 164     -11.761 -36.693 -17.259  1.00 37.71           O  
ATOM   1222  CB  THR A 164     -10.869 -33.552 -17.248  1.00 43.41           C  
ATOM   1223  OG1 THR A 164      -9.690 -34.365 -17.298  1.00 41.43           O  
ATOM   1224  CG2 THR A 164     -10.596 -32.312 -16.400  1.00 45.19           C  
ATOM   1225  N   ASN A 165     -12.893 -35.374 -18.694  1.00 42.62           N  
ATOM   1226  CA  ASN A 165     -13.120 -36.423 -19.688  1.00 45.67           C  
ATOM   1227  C   ASN A 165     -11.821 -36.890 -20.342  1.00 46.30           C  
ATOM   1228  O   ASN A 165     -11.663 -38.076 -20.623  1.00 47.90           O  
ATOM   1229  CB  ASN A 165     -14.135 -35.972 -20.755  1.00 49.52           C  
ATOM   1230  CG  ASN A 165     -15.580 -36.163 -20.304  1.00 53.48           C  
ATOM   1231  OD1 ASN A 165     -15.948 -35.780 -19.192  1.00 57.98           O  
ATOM   1232  ND2 ASN A 165     -16.406 -36.756 -21.167  1.00 55.44           N  
ATOM   1233  N   GLU A 166     -10.895 -35.964 -20.580  1.00 46.32           N  
ATOM   1234  CA  GLU A 166      -9.589 -36.339 -21.112  1.00 51.56           C  
ATOM   1235  C   GLU A 166      -8.914 -37.318 -20.153  1.00 46.77           C  
ATOM   1236  O   GLU A 166      -8.342 -38.295 -20.578  1.00 48.76           O  
ATOM   1237  CB  GLU A 166      -8.676 -35.120 -21.349  1.00 53.74           C  
ATOM   1238  CG  GLU A 166      -7.207 -35.516 -21.563  1.00 60.20           C  
ATOM   1239  CD  GLU A 166      -6.424 -34.594 -22.491  1.00 66.48           C  
ATOM   1240  OE1 GLU A 166      -6.848 -34.404 -23.653  1.00 72.76           O  
ATOM   1241  OE2 GLU A 166      -5.365 -34.084 -22.065  1.00 68.19           O  
ATOM   1242  N   GLU A 167      -8.981 -37.035 -18.861  1.00 47.63           N  
ATOM   1243  CA  GLU A 167      -8.390 -37.919 -17.860  1.00 52.31           C  
ATOM   1244  C   GLU A 167      -9.136 -39.262 -17.829  1.00 50.84           C  
ATOM   1245  O   GLU A 167      -8.522 -40.330 -17.905  1.00 46.98           O  
ATOM   1246  CB  GLU A 167      -8.413 -37.232 -16.489  1.00 57.17           C  
ATOM   1247  CG  GLU A 167      -7.983 -38.084 -15.295  1.00 62.42           C  
ATOM   1248  CD  GLU A 167      -6.530 -38.506 -15.338  1.00 63.80           C  
ATOM   1249  OE1 GLU A 167      -5.728 -37.876 -16.069  1.00 70.06           O  
ATOM   1250  OE2 GLU A 167      -6.192 -39.475 -14.627  1.00 65.45           O  
ATOM   1251  N   CYS A 168     -10.459 -39.199 -17.725  1.00 47.01           N  
ATOM   1252  CA  CYS A 168     -11.278 -40.424 -17.722  1.00 46.30           C  
ATOM   1253  C   CYS A 168     -11.002 -41.328 -18.941  1.00 44.09           C  
ATOM   1254  O   CYS A 168     -10.833 -42.534 -18.800  1.00 43.56           O  
ATOM   1255  CB  CYS A 168     -12.768 -40.083 -17.678  1.00 44.40           C  
ATOM   1256  SG  CYS A 168     -13.808 -41.481 -17.134  1.00 42.89           S  
ATOM   1257  N   GLN A 169     -10.957 -40.720 -20.120  1.00 42.59           N  
ATOM   1258  CA  GLN A 169     -10.645 -41.438 -21.361  1.00 48.57           C  
ATOM   1259  C   GLN A 169      -9.307 -42.217 -21.301  1.00 50.36           C  
ATOM   1260  O   GLN A 169      -9.233 -43.346 -21.778  1.00 50.62           O  
ATOM   1261  CB  GLN A 169     -10.662 -40.468 -22.555  1.00 47.90           C  
ATOM   1262  CG  GLN A 169     -10.430 -41.101 -23.934  1.00 47.77           C  
ATOM   1263  CD  GLN A 169     -11.472 -42.138 -24.326  1.00 43.56           C  
ATOM   1264  OE1 GLN A 169     -12.496 -41.816 -24.920  1.00 48.37           O  
ATOM   1265  NE2 GLN A 169     -11.196 -43.398 -24.019  1.00 47.44           N  
ATOM   1266  N   LYS A 170      -8.268 -41.623 -20.708  1.00 50.79           N  
ATOM   1267  CA  LYS A 170      -6.962 -42.302 -20.562  1.00 52.17           C  
ATOM   1268  C   LYS A 170      -7.054 -43.553 -19.694  1.00 49.40           C  
ATOM   1269  O   LYS A 170      -6.252 -44.472 -19.837  1.00 44.52           O  
ATOM   1270  CB  LYS A 170      -5.906 -41.363 -19.949  1.00 56.50           C  
ATOM   1271  CG  LYS A 170      -5.203 -40.458 -20.954  1.00 61.70           C  
ATOM   1272  CD  LYS A 170      -4.267 -39.459 -20.278  1.00 65.14           C  
ATOM   1273  CE  LYS A 170      -3.585 -38.562 -21.309  1.00 69.53           C  
ATOM   1274  NZ  LYS A 170      -3.284 -37.196 -20.789  1.00 71.24           N  
ATOM   1275  N   ARG A 171      -8.010 -43.562 -18.769  1.00 45.13           N  
ATOM   1276  CA  ARG A 171      -8.205 -44.688 -17.872  1.00 45.05           C  
ATOM   1277  C   ARG A 171      -9.072 -45.771 -18.489  1.00 40.95           C  
ATOM   1278  O   ARG A 171      -9.087 -46.896 -18.006  1.00 38.95           O  
ATOM   1279  CB  ARG A 171      -8.834 -44.212 -16.547  1.00 46.54           C  
ATOM   1280  CG  ARG A 171      -8.088 -43.080 -15.859  1.00 46.48           C  
ATOM   1281  CD  ARG A 171      -6.596 -43.363 -15.819  1.00 56.03           C  
ATOM   1282  NE  ARG A 171      -5.807 -42.209 -15.399  1.00 59.85           N  
ATOM   1283  CZ  ARG A 171      -4.478 -42.199 -15.347  1.00 62.85           C  
ATOM   1284  NH1 ARG A 171      -3.782 -43.289 -15.668  1.00 64.19           N  
ATOM   1285  NH2 ARG A 171      -3.843 -41.102 -14.962  1.00 63.30           N  
ATOM   1286  N   TYR A 172      -9.838 -45.418 -19.519  1.00 40.52           N  
ATOM   1287  CA  TYR A 172     -10.677 -46.388 -20.195  1.00 39.13           C  
ATOM   1288  C   TYR A 172     -10.338 -46.390 -21.695  1.00 39.55           C  
ATOM   1289  O   TYR A 172     -11.132 -45.948 -22.530  1.00 37.78           O  
ATOM   1290  CB  TYR A 172     -12.157 -46.100 -19.953  1.00 37.04           C  
ATOM   1291  CG  TYR A 172     -12.644 -46.369 -18.537  1.00 35.32           C  
ATOM   1292  CD1 TYR A 172     -12.961 -47.646 -18.129  1.00 35.01           C  
ATOM   1293  CD2 TYR A 172     -12.826 -45.329 -17.623  1.00 34.82           C  
ATOM   1294  CE1 TYR A 172     -13.421 -47.903 -16.850  1.00 35.76           C  
ATOM   1295  CE2 TYR A 172     -13.282 -45.577 -16.344  1.00 35.70           C  
ATOM   1296  CZ  TYR A 172     -13.589 -46.868 -15.969  1.00 35.38           C  
ATOM   1297  OH  TYR A 172     -14.026 -47.160 -14.714  1.00 37.90           O  
ATOM   1298  N   ARG A 173      -9.151 -46.899 -22.008  1.00 41.36           N  
ATOM   1299  CA  ARG A 173      -8.644 -46.958 -23.391  1.00 47.79           C  
ATOM   1300  C   ARG A 173      -9.527 -47.764 -24.335  1.00 44.80           C  
ATOM   1301  O   ARG A 173      -9.593 -47.455 -25.504  1.00 47.58           O  
ATOM   1302  CB  ARG A 173      -7.254 -47.582 -23.431  1.00 53.00           C  
ATOM   1303  CG  ARG A 173      -6.192 -46.732 -22.797  1.00 61.52           C  
ATOM   1304  CD  ARG A 173      -5.750 -45.607 -23.723  1.00 67.81           C  
ATOM   1305  NE  ARG A 173      -4.963 -44.661 -22.952  1.00 76.78           N  
ATOM   1306  CZ  ARG A 173      -3.725 -44.878 -22.508  1.00 81.04           C  
ATOM   1307  NH1 ARG A 173      -3.078 -46.013 -22.783  1.00 86.78           N  
ATOM   1308  NH2 ARG A 173      -3.123 -43.940 -21.788  1.00 80.81           N  
ATOM   1309  N   GLY A 173A    -10.191 -48.801 -23.830  1.00 44.56           N  
ATOM   1310  CA  GLY A 173A    -11.089 -49.609 -24.658  1.00 42.72           C  
ATOM   1311  C   GLY A 173A    -12.511 -49.104 -24.824  1.00 40.46           C  
ATOM   1312  O   GLY A 173A    -13.309 -49.748 -25.475  1.00 41.13           O  
ATOM   1313  N   HIS A 174     -12.841 -47.970 -24.214  1.00 39.32           N  
ATOM   1314  CA  HIS A 174     -14.169 -47.398 -24.335  1.00 39.19           C  
ATOM   1315  C   HIS A 174     -14.053 -46.020 -24.970  1.00 40.85           C  
ATOM   1316  O   HIS A 174     -12.989 -45.404 -24.967  1.00 43.19           O  
ATOM   1317  CB  HIS A 174     -14.847 -47.229 -22.960  1.00 37.38           C  
ATOM   1318  CG  HIS A 174     -15.148 -48.514 -22.255  1.00 35.60           C  
ATOM   1319  ND1 HIS A 174     -14.201 -49.200 -21.543  1.00 33.71           N  
ATOM   1320  CD2 HIS A 174     -16.298 -49.217 -22.123  1.00 36.26           C  
ATOM   1321  CE1 HIS A 174     -14.746 -50.277 -21.006  1.00 36.10           C  
ATOM   1322  NE2 HIS A 174     -16.018 -50.312 -21.342  1.00 35.36           N  
ATOM   1323  N   LYS A 175     -15.171 -45.533 -25.474  1.00 40.74           N  
ATOM   1324  CA  LYS A 175     -15.290 -44.145 -25.841  1.00 43.91           C  
ATOM   1325  C   LYS A 175     -15.978 -43.349 -24.712  1.00 39.06           C  
ATOM   1326  O   LYS A 175     -17.181 -43.458 -24.517  1.00 38.35           O  
ATOM   1327  CB  LYS A 175     -16.070 -44.033 -27.154  1.00 46.41           C  
ATOM   1328  CG  LYS A 175     -16.164 -42.619 -27.713  1.00 51.88           C  
ATOM   1329  CD  LYS A 175     -14.837 -41.859 -27.615  1.00 57.27           C  
ATOM   1330  CE  LYS A 175     -15.013 -40.405 -27.187  1.00 59.63           C  
ATOM   1331  NZ  LYS A 175     -14.731 -39.462 -28.300  1.00 59.15           N  
ATOM   1332  N   ILE A 176     -15.209 -42.563 -23.958  1.00 39.45           N  
ATOM   1333  CA  ILE A 176     -15.801 -41.697 -22.913  1.00 40.12           C  
ATOM   1334  C   ILE A 176     -16.290 -40.420 -23.574  1.00 39.01           C  
ATOM   1335  O   ILE A 176     -15.499 -39.595 -23.980  1.00 40.57           O  
ATOM   1336  CB  ILE A 176     -14.818 -41.346 -21.789  1.00 40.84           C  
ATOM   1337  CG1 ILE A 176     -14.239 -42.606 -21.153  1.00 41.62           C  
ATOM   1338  CG2 ILE A 176     -15.503 -40.492 -20.718  1.00 37.94           C  
ATOM   1339  CD1 ILE A 176     -15.272 -43.560 -20.576  1.00 43.27           C  
ATOM   1340  N   THR A 177     -17.596 -40.277 -23.689  1.00 38.37           N  
ATOM   1341  CA  THR A 177     -18.170 -39.203 -24.486  1.00 40.15           C  
ATOM   1342  C   THR A 177     -18.489 -37.997 -23.630  1.00 41.09           C  
ATOM   1343  O   THR A 177     -18.475 -38.078 -22.399  1.00 43.96           O  
ATOM   1344  CB  THR A 177     -19.474 -39.641 -25.160  1.00 39.84           C  
ATOM   1345  OG1 THR A 177     -20.534 -39.666 -24.186  1.00 40.79           O  
ATOM   1346  CG2 THR A 177     -19.307 -41.021 -25.796  1.00 39.26           C  
ATOM   1347  N   HIS A 178     -18.812 -36.893 -24.293  1.00 41.01           N  
ATOM   1348  CA  HIS A 178     -19.181 -35.653 -23.608  1.00 43.33           C  
ATOM   1349  C   HIS A 178     -20.550 -35.778 -22.880  1.00 40.60           C  
ATOM   1350  O   HIS A 178     -20.926 -34.919 -22.086  1.00 41.98           O  
ATOM   1351  CB  HIS A 178     -19.160 -34.464 -24.581  1.00 42.24           C  
ATOM   1352  CG  HIS A 178     -20.233 -34.506 -25.626  1.00 45.07           C  
ATOM   1353  ND1 HIS A 178     -20.067 -35.141 -26.840  1.00 47.12           N  
ATOM   1354  CD2 HIS A 178     -21.481 -33.980 -25.646  1.00 44.64           C  
ATOM   1355  CE1 HIS A 178     -21.168 -35.011 -27.559  1.00 47.10           C  
ATOM   1356  NE2 HIS A 178     -22.041 -34.308 -26.860  1.00 45.47           N  
ATOM   1357  N   LYS A 179     -21.274 -36.857 -23.142  1.00 39.07           N  
ATOM   1358  CA  LYS A 179     -22.502 -37.172 -22.420  1.00 38.17           C  
ATOM   1359  C   LYS A 179     -22.263 -38.035 -21.181  1.00 36.56           C  
ATOM   1360  O   LYS A 179     -23.202 -38.435 -20.500  1.00 32.50           O  
ATOM   1361  CB  LYS A 179     -23.477 -37.844 -23.364  1.00 40.49           C  
ATOM   1362  CG  LYS A 179     -23.962 -36.882 -24.430  1.00 42.69           C  
ATOM   1363  CD  LYS A 179     -24.852 -37.569 -25.437  1.00 48.41           C  
ATOM   1364  CE  LYS A 179     -25.282 -36.605 -26.519  1.00 50.22           C  
ATOM   1365  NZ  LYS A 179     -26.129 -35.522 -25.947  1.00 56.26           N  
ATOM   1366  N   MET A 180     -21.002 -38.321 -20.893  1.00 36.32           N  
ATOM   1367  CA  MET A 180     -20.632 -38.979 -19.662  1.00 37.56           C  
ATOM   1368  C   MET A 180     -19.845 -38.004 -18.797  1.00 39.48           C  
ATOM   1369  O   MET A 180     -19.295 -37.016 -19.294  1.00 36.91           O  
ATOM   1370  CB  MET A 180     -19.781 -40.190 -19.951  1.00 36.03           C  
ATOM   1371  CG  MET A 180     -20.480 -41.220 -20.808  1.00 36.92           C  
ATOM   1372  SD  MET A 180     -19.323 -42.446 -21.421  1.00 35.77           S  
ATOM   1373  CE  MET A 180     -20.417 -43.415 -22.455  1.00 36.95           C  
ATOM   1374  N   ILE A 181     -19.825 -38.278 -17.500  1.00 37.55           N  
ATOM   1375  CA  ILE A 181     -18.940 -37.554 -16.604  1.00 39.47           C  
ATOM   1376  C   ILE A 181     -18.379 -38.557 -15.611  1.00 36.09           C  
ATOM   1377  O   ILE A 181     -19.058 -39.528 -15.252  1.00 37.93           O  
ATOM   1378  CB  ILE A 181     -19.656 -36.323 -15.970  1.00 39.32           C  
ATOM   1379  CG1 ILE A 181     -18.666 -35.489 -15.168  1.00 42.54           C  
ATOM   1380  CG2 ILE A 181     -20.831 -36.747 -15.105  1.00 39.62           C  
ATOM   1381  CD1 ILE A 181     -19.168 -34.086 -14.918  1.00 47.66           C  
ATOM   1382  N   CYS A 182     -17.138 -38.335 -15.203  1.00 34.49           N  
ATOM   1383  CA  CYS A 182     -16.386 -39.276 -14.383  1.00 36.71           C  
ATOM   1384  C   CYS A 182     -15.888 -38.702 -13.057  1.00 38.35           C  
ATOM   1385  O   CYS A 182     -15.486 -37.531 -12.980  1.00 38.10           O  
ATOM   1386  CB  CYS A 182     -15.171 -39.744 -15.160  1.00 39.87           C  
ATOM   1387  SG  CYS A 182     -15.556 -40.514 -16.737  1.00 41.82           S  
ATOM   1388  N   ALA A 183     -15.863 -39.551 -12.037  1.00 40.21           N  
ATOM   1389  CA  ALA A 183     -15.459 -39.141 -10.692  1.00 42.21           C  
ATOM   1390  C   ALA A 183     -14.708 -40.266 -10.007  1.00 40.76           C  
ATOM   1391  O   ALA A 183     -15.098 -41.414 -10.125  1.00 41.22           O  
ATOM   1392  CB  ALA A 183     -16.698 -38.763  -9.892  1.00 41.87           C  
ATOM   1393  N   GLY A 184     -13.624 -39.936  -9.307  1.00 40.84           N  
ATOM   1394  CA  GLY A 184     -12.816 -40.925  -8.602  1.00 39.48           C  
ATOM   1395  C   GLY A 184     -11.466 -40.416  -8.105  1.00 40.69           C  
ATOM   1396  O   GLY A 184     -10.972 -39.404  -8.570  1.00 40.93           O  
ATOM   1397  N   TYR A 184A    -10.878 -41.146  -7.161  1.00 43.83           N  
ATOM   1398  CA  TYR A 184A     -9.520 -40.895  -6.691  1.00 44.12           C  
ATOM   1399  C   TYR A 184A     -8.515 -41.691  -7.527  1.00 47.76           C  
ATOM   1400  O   TYR A 184A     -8.705 -42.894  -7.775  1.00 39.60           O  
ATOM   1401  CB  TYR A 184A     -9.387 -41.279  -5.209  1.00 46.58           C  
ATOM   1402  CG  TYR A 184A    -10.217 -40.400  -4.293  1.00 47.22           C  
ATOM   1403  CD1 TYR A 184A     -9.721 -39.181  -3.818  1.00 48.41           C  
ATOM   1404  CD2 TYR A 184A    -11.504 -40.767  -3.943  1.00 48.17           C  
ATOM   1405  CE1 TYR A 184A    -10.487 -38.365  -3.000  1.00 50.28           C  
ATOM   1406  CE2 TYR A 184A    -12.280 -39.959  -3.130  1.00 49.27           C  
ATOM   1407  CZ  TYR A 184A    -11.770 -38.765  -2.664  1.00 49.77           C  
ATOM   1408  OH  TYR A 184A    -12.545 -37.983  -1.865  1.00 48.39           O  
ATOM   1409  N   ARG A 185      -7.432 -41.029  -7.940  1.00 48.60           N  
ATOM   1410  CA  ARG A 185      -6.346 -41.694  -8.670  1.00 51.25           C  
ATOM   1411  C   ARG A 185      -5.992 -43.004  -8.013  1.00 49.63           C  
ATOM   1412  O   ARG A 185      -5.773 -44.013  -8.682  1.00 50.92           O  
ATOM   1413  CB  ARG A 185      -5.096 -40.817  -8.707  1.00 57.64           C  
ATOM   1414  CG  ARG A 185      -3.946 -41.442  -9.486  1.00 63.90           C  
ATOM   1415  CD  ARG A 185      -2.671 -40.621  -9.368  1.00 70.40           C  
ATOM   1416  NE  ARG A 185      -1.713 -41.027 -10.391  1.00 75.49           N  
ATOM   1417  CZ  ARG A 185      -1.784 -40.688 -11.677  1.00 77.39           C  
ATOM   1418  NH1 ARG A 185      -2.765 -39.911 -12.131  1.00 77.32           N  
ATOM   1419  NH2 ARG A 185      -0.859 -41.127 -12.522  1.00 81.15           N  
ATOM   1420  N   GLU A 186      -5.934 -42.969  -6.686  1.00 47.81           N  
ATOM   1421  CA  GLU A 186      -5.594 -44.137  -5.883  1.00 46.03           C  
ATOM   1422  C   GLU A 186      -6.826 -44.969  -5.472  1.00 42.91           C  
ATOM   1423  O   GLU A 186      -6.687 -45.905  -4.710  1.00 41.54           O  
ATOM   1424  CB  GLU A 186      -4.782 -43.720  -4.635  1.00 45.24           C  
ATOM   1425  CG  GLU A 186      -5.588 -43.036  -3.527  0.50 44.87           C  
ATOM   1426  CD  GLU A 186      -5.803 -41.548  -3.740  0.50 43.97           C  
ATOM   1427  OE1 GLU A 186      -5.552 -41.037  -4.851  0.50 42.87           O  
ATOM   1428  OE2 GLU A 186      -6.231 -40.883  -2.779  0.50 46.65           O  
ATOM   1429  N   GLY A 187      -8.015 -44.618  -5.964  1.00 44.31           N  
ATOM   1430  CA  GLY A 187      -9.240 -45.387  -5.716  1.00 43.00           C  
ATOM   1431  C   GLY A 187      -9.706 -45.259  -4.283  1.00 42.83           C  
ATOM   1432  O   GLY A 187      -9.396 -44.277  -3.630  1.00 40.71           O  
ATOM   1433  N   GLY A 188     -10.468 -46.241  -3.807  1.00 43.48           N  
ATOM   1434  CA  GLY A 188     -10.851 -46.327  -2.389  1.00 42.21           C  
ATOM   1435  C   GLY A 188     -12.264 -45.874  -2.081  1.00 41.65           C  
ATOM   1436  O   GLY A 188     -12.846 -46.317  -1.101  1.00 42.57           O  
ATOM   1437  N   LYS A 188A    -12.811 -44.992  -2.910  1.00 39.88           N  
ATOM   1438  CA  LYS A 188A    -14.190 -44.525  -2.754  1.00 40.14           C  
ATOM   1439  C   LYS A 188A    -14.900 -44.526  -4.090  1.00 36.39           C  
ATOM   1440  O   LYS A 188A    -14.400 -43.952  -5.038  1.00 34.08           O  
ATOM   1441  CB  LYS A 188A    -14.219 -43.100  -2.171  1.00 41.22           C  
ATOM   1442  CG  LYS A 188A    -13.703 -43.001  -0.741  1.00 42.17           C  
ATOM   1443  CD  LYS A 188A    -13.868 -41.596  -0.175  1.00 46.03           C  
ATOM   1444  CE  LYS A 188A    -13.055 -41.456   1.096  1.00 48.30           C  
ATOM   1445  NZ  LYS A 188A    -13.244 -40.130   1.727  1.00 50.53           N  
ATOM   1446  N   ASP A 189     -16.091 -45.125  -4.151  1.00 38.16           N  
ATOM   1447  CA  ASP A 189     -16.806 -45.293  -5.424  1.00 35.18           C  
ATOM   1448  C   ASP A 189     -18.179 -45.890  -5.190  1.00 32.47           C  
ATOM   1449  O   ASP A 189     -18.437 -46.508  -4.157  1.00 36.19           O  
ATOM   1450  CB  ASP A 189     -16.022 -46.285  -6.304  1.00 37.37           C  
ATOM   1451  CG  ASP A 189     -16.305 -46.157  -7.828  1.00 37.77           C  
ATOM   1452  OD1 ASP A 189     -16.964 -45.189  -8.317  1.00 34.70           O  
ATOM   1453  OD2 ASP A 189     -15.789 -47.059  -8.552  1.00 40.18           O  
ATOM   1454  N   ALA A 190     -19.050 -45.710  -6.167  1.00 30.43           N  
ATOM   1455  CA  ALA A 190     -20.230 -46.548  -6.301  1.00 31.10           C  
ATOM   1456  C   ALA A 190     -19.846 -47.998  -6.426  1.00 32.71           C  
ATOM   1457  O   ALA A 190     -18.686 -48.328  -6.753  1.00 32.69           O  
ATOM   1458  CB  ALA A 190     -21.028 -46.138  -7.526  1.00 31.81           C  
ATOM   1459  N   CYS A 191     -20.822 -48.875  -6.192  1.00 32.22           N  
ATOM   1460  CA  CYS A 191     -20.649 -50.290  -6.503  1.00 31.43           C  
ATOM   1461  C   CYS A 191     -22.013 -50.939  -6.747  1.00 31.93           C  
ATOM   1462  O   CYS A 191     -23.025 -50.245  -6.827  1.00 30.87           O  
ATOM   1463  CB  CYS A 191     -19.861 -51.020  -5.382  1.00 33.35           C  
ATOM   1464  SG  CYS A 191     -19.089 -52.596  -5.863  1.00 37.20           S  
ATOM   1465  N   LYS A 192     -22.041 -52.264  -6.896  1.00 31.31           N  
ATOM   1466  CA  LYS A 192     -23.294 -52.962  -7.280  1.00 34.01           C  
ATOM   1467  C   LYS A 192     -24.468 -52.621  -6.353  1.00 30.30           C  
ATOM   1468  O   LYS A 192     -24.376 -52.813  -5.149  1.00 34.06           O  
ATOM   1469  CB  LYS A 192     -23.102 -54.477  -7.279  1.00 34.28           C  
ATOM   1470  CG  LYS A 192     -22.192 -54.959  -8.391  1.00 39.65           C  
ATOM   1471  CD  LYS A 192     -21.766 -56.408  -8.230  1.00 40.79           C  
ATOM   1472  CE  LYS A 192     -20.979 -56.833  -9.475  1.00 44.94           C  
ATOM   1473  NZ  LYS A 192     -20.556 -58.243  -9.362  1.00 49.11           N  
ATOM   1474  N   GLY A 193     -25.562 -52.154  -6.926  1.00 31.08           N  
ATOM   1475  CA  GLY A 193     -26.737 -51.721  -6.148  1.00 31.18           C  
ATOM   1476  C   GLY A 193     -26.880 -50.202  -6.086  1.00 30.87           C  
ATOM   1477  O   GLY A 193     -27.961 -49.706  -5.778  1.00 30.75           O  
ATOM   1478  N   ASP A 194     -25.797 -49.471  -6.361  1.00 30.10           N  
ATOM   1479  CA  ASP A 194     -25.829 -47.995  -6.380  1.00 31.81           C  
ATOM   1480  C   ASP A 194     -26.367 -47.384  -7.677  1.00 31.66           C  
ATOM   1481  O   ASP A 194     -26.749 -46.204  -7.698  1.00 30.36           O  
ATOM   1482  CB  ASP A 194     -24.416 -47.430  -6.078  1.00 29.98           C  
ATOM   1483  CG  ASP A 194     -23.967 -47.707  -4.663  1.00 30.40           C  
ATOM   1484  OD1 ASP A 194     -24.808 -47.536  -3.752  1.00 30.73           O  
ATOM   1485  OD2 ASP A 194     -22.783 -48.101  -4.441  1.00 28.94           O  
ATOM   1486  N   SER A 195     -26.398 -48.142  -8.779  1.00 30.43           N  
ATOM   1487  CA  SER A 195     -26.678 -47.479 -10.083  1.00 29.80           C  
ATOM   1488  C   SER A 195     -28.076 -46.896 -10.146  1.00 28.97           C  
ATOM   1489  O   SER A 195     -28.963 -47.324  -9.422  1.00 26.68           O  
ATOM   1490  CB  SER A 195     -26.457 -48.379 -11.271  1.00 32.94           C  
ATOM   1491  OG  SER A 195     -27.431 -49.409 -11.319  1.00 36.90           O  
ATOM   1492  N   GLY A 196     -28.252 -45.894 -11.014  1.00 27.33           N  
ATOM   1493  CA  GLY A 196     -29.503 -45.160 -11.096  1.00 28.78           C  
ATOM   1494  C   GLY A 196     -29.584 -44.043 -10.070  1.00 27.73           C  
ATOM   1495  O   GLY A 196     -30.347 -43.119 -10.240  1.00 32.68           O  
ATOM   1496  N   GLY A 197     -28.779 -44.138  -9.017  1.00 31.16           N  
ATOM   1497  CA  GLY A 197     -28.703 -43.116  -7.995  1.00 33.48           C  
ATOM   1498  C   GLY A 197     -28.002 -41.862  -8.464  1.00 34.23           C  
ATOM   1499  O   GLY A 197     -27.415 -41.845  -9.534  1.00 33.28           O  
ATOM   1500  N   PRO A 198     -28.090 -40.787  -7.668  1.00 33.90           N  
ATOM   1501  CA  PRO A 198     -27.519 -39.494  -8.008  1.00 34.07           C  
ATOM   1502  C   PRO A 198     -26.028 -39.368  -7.730  1.00 31.91           C  
ATOM   1503  O   PRO A 198     -25.501 -39.996  -6.814  1.00 30.56           O  
ATOM   1504  CB  PRO A 198     -28.271 -38.540  -7.081  1.00 35.34           C  
ATOM   1505  CG  PRO A 198     -28.547 -39.346  -5.884  1.00 35.25           C  
ATOM   1506  CD  PRO A 198     -28.830 -40.738  -6.402  1.00 36.62           C  
ATOM   1507  N   LEU A 198A    -25.370 -38.547  -8.541  1.00 33.04           N  
ATOM   1508  CA  LEU A 198A    -24.118 -37.911  -8.144  1.00 33.65           C  
ATOM   1509  C   LEU A 198A    -24.525 -36.463  -7.854  1.00 33.15           C  
ATOM   1510  O   LEU A 198A    -24.885 -35.709  -8.773  1.00 34.08           O  
ATOM   1511  CB  LEU A 198A    -23.063 -37.953  -9.258  1.00 34.28           C  
ATOM   1512  CG  LEU A 198A    -21.742 -37.231  -8.967  1.00 34.70           C  
ATOM   1513  CD1 LEU A 198A    -20.962 -37.978  -7.913  1.00 37.61           C  
ATOM   1514  CD2 LEU A 198A    -20.882 -37.090 -10.212  1.00 36.78           C  
ATOM   1515  N   SER A 198B    -24.487 -36.082  -6.587  1.00 31.42           N  
ATOM   1516  CA  SER A 198B    -25.067 -34.778  -6.182  1.00 35.57           C  
ATOM   1517  C   SER A 198B    -23.938 -33.797  -5.888  1.00 35.71           C  
ATOM   1518  O   SER A 198B    -23.097 -34.094  -5.058  1.00 36.01           O  
ATOM   1519  CB  SER A 198B    -25.945 -34.943  -4.937  1.00 33.53           C  
ATOM   1520  OG  SER A 198B    -26.765 -36.112  -4.986  1.00 34.64           O  
ATOM   1521  N   CYS A 201     -23.916 -32.641  -6.561  1.00 38.48           N  
ATOM   1522  CA  CYS A 201     -22.903 -31.616  -6.266  1.00 43.22           C  
ATOM   1523  C   CYS A 201     -23.517 -30.311  -5.754  1.00 42.16           C  
ATOM   1524  O   CYS A 201     -24.415 -29.741  -6.361  1.00 39.59           O  
ATOM   1525  CB  CYS A 201     -22.016 -31.295  -7.479  1.00 45.42           C  
ATOM   1526  SG  CYS A 201     -21.341 -32.727  -8.344  1.00 42.39           S  
ATOM   1527  N   LYS A 202     -22.994 -29.830  -4.637  1.00 45.00           N  
ATOM   1528  CA  LYS A 202     -23.489 -28.577  -4.079  1.00 49.85           C  
ATOM   1529  C   LYS A 202     -22.730 -27.412  -4.675  1.00 45.99           C  
ATOM   1530  O   LYS A 202     -21.521 -27.384  -4.624  1.00 50.03           O  
ATOM   1531  CB  LYS A 202     -23.360 -28.566  -2.573  1.00 49.05           C  
ATOM   1532  CG  LYS A 202     -24.246 -27.533  -1.906  1.00 52.20           C  
ATOM   1533  CD  LYS A 202     -23.845 -27.391  -0.449  1.00 56.70           C  
ATOM   1534  CE  LYS A 202     -25.023 -27.059   0.433  1.00 60.47           C  
ATOM   1535  NZ  LYS A 202     -24.585 -27.047   1.855  1.00 66.71           N  
ATOM   1536  N   HIS A 202A    -23.453 -26.469  -5.255  1.00 48.14           N  
ATOM   1537  CA  HIS A 202A    -22.853 -25.256  -5.806  1.00 54.44           C  
ATOM   1538  C   HIS A 202A    -23.745 -24.055  -5.516  1.00 52.94           C  
ATOM   1539  O   HIS A 202A    -24.935 -24.067  -5.850  1.00 51.00           O  
ATOM   1540  CB  HIS A 202A    -22.655 -25.393  -7.317  1.00 53.31           C  
ATOM   1541  CG  HIS A 202A    -21.672 -24.419  -7.892  1.00 57.93           C  
ATOM   1542  ND1 HIS A 202A    -21.969 -23.618  -8.974  1.00 60.60           N  
ATOM   1543  CD2 HIS A 202A    -20.392 -24.131  -7.548  1.00 56.32           C  
ATOM   1544  CE1 HIS A 202A    -20.919 -22.871  -9.267  1.00 62.72           C  
ATOM   1545  NE2 HIS A 202A    -19.949 -23.165  -8.418  1.00 62.41           N  
ATOM   1546  N   ASN A 202B    -23.155 -23.013  -4.932  1.00 56.83           N  
ATOM   1547  CA  ASN A 202B    -23.891 -21.794  -4.569  1.00 56.08           C  
ATOM   1548  C   ASN A 202B    -25.057 -22.121  -3.663  1.00 54.66           C  
ATOM   1549  O   ASN A 202B    -26.197 -21.701  -3.903  1.00 57.32           O  
ATOM   1550  CB  ASN A 202B    -24.359 -21.042  -5.820  1.00 56.60           C  
ATOM   1551  CG  ASN A 202B    -23.203 -20.483  -6.615  1.00 57.12           C  
ATOM   1552  OD1 ASN A 202B    -22.081 -20.387  -6.115  1.00 58.00           O  
ATOM   1553  ND2 ASN A 202B    -23.470 -20.101  -7.859  1.00 60.00           N  
ATOM   1554  N   GLU A 202C    -24.751 -22.915  -2.639  1.00 58.97           N  
ATOM   1555  CA  GLU A 202C    -25.701 -23.290  -1.595  1.00 64.14           C  
ATOM   1556  C   GLU A 202C    -26.840 -24.182  -2.064  1.00 59.91           C  
ATOM   1557  O   GLU A 202C    -27.721 -24.499  -1.275  1.00 60.92           O  
ATOM   1558  CB  GLU A 202C    -26.281 -22.037  -0.921  1.00 69.72           C  
ATOM   1559  CG  GLU A 202C    -25.230 -21.067  -0.386  1.00 75.21           C  
ATOM   1560  CD  GLU A 202C    -24.268 -21.706   0.615  1.00 80.12           C  
ATOM   1561  OE1 GLU A 202C    -24.639 -22.693   1.290  1.00 83.61           O  
ATOM   1562  OE2 GLU A 202C    -23.128 -21.216   0.741  1.00 82.14           O  
ATOM   1563  N   VAL A 202D    -26.809 -24.595  -3.329  1.00 57.36           N  
ATOM   1564  CA  VAL A 202D    -27.847 -25.462  -3.908  1.00 54.64           C  
ATOM   1565  C   VAL A 202D    -27.233 -26.790  -4.413  1.00 51.87           C  
ATOM   1566  O   VAL A 202D    -26.084 -26.847  -4.874  1.00 45.05           O  
ATOM   1567  CB  VAL A 202D    -28.597 -24.734  -5.045  1.00 57.28           C  
ATOM   1568  CG1 VAL A 202D    -29.577 -25.663  -5.764  1.00 59.08           C  
ATOM   1569  CG2 VAL A 202D    -29.328 -23.512  -4.486  1.00 60.62           C  
ATOM   1570  N   TRP A 203     -28.009 -27.862  -4.298  1.00 50.83           N  
ATOM   1571  CA  TRP A 203     -27.603 -29.171  -4.810  1.00 45.80           C  
ATOM   1572  C   TRP A 203     -28.114 -29.402  -6.240  1.00 44.18           C  
ATOM   1573  O   TRP A 203     -29.304 -29.220  -6.540  1.00 41.35           O  
ATOM   1574  CB  TRP A 203     -28.133 -30.270  -3.910  1.00 44.05           C  
ATOM   1575  CG  TRP A 203     -27.493 -30.372  -2.585  1.00 39.02           C  
ATOM   1576  CD1 TRP A 203     -27.974 -29.888  -1.402  1.00 36.42           C  
ATOM   1577  CD2 TRP A 203     -26.274 -31.051  -2.281  1.00 40.93           C  
ATOM   1578  NE1 TRP A 203     -27.122 -30.212  -0.381  1.00 39.01           N  
ATOM   1579  CE2 TRP A 203     -26.066 -30.922  -0.891  1.00 37.50           C  
ATOM   1580  CE3 TRP A 203     -25.312 -31.721  -3.058  1.00 39.72           C  
ATOM   1581  CZ2 TRP A 203     -24.965 -31.462  -0.252  1.00 39.66           C  
ATOM   1582  CZ3 TRP A 203     -24.195 -32.268  -2.414  1.00 38.54           C  
ATOM   1583  CH2 TRP A 203     -24.031 -32.127  -1.028  1.00 41.97           C  
ATOM   1584  N   HIS A 204     -27.206 -29.821  -7.114  1.00 44.32           N  
ATOM   1585  CA  HIS A 204     -27.553 -30.132  -8.503  1.00 43.64           C  
ATOM   1586  C   HIS A 204     -27.343 -31.619  -8.790  1.00 39.29           C  
ATOM   1587  O   HIS A 204     -26.450 -32.257  -8.237  1.00 36.98           O  
ATOM   1588  CB  HIS A 204     -26.694 -29.296  -9.447  1.00 48.94           C  
ATOM   1589  CG  HIS A 204     -26.845 -27.823  -9.238  1.00 55.03           C  
ATOM   1590  ND1 HIS A 204     -26.274 -27.163  -8.168  1.00 59.74           N  
ATOM   1591  CD2 HIS A 204     -27.512 -26.884  -9.948  1.00 59.59           C  
ATOM   1592  CE1 HIS A 204     -26.580 -25.882  -8.229  1.00 58.72           C  
ATOM   1593  NE2 HIS A 204     -27.332 -25.686  -9.298  1.00 63.97           N  
ATOM   1594  N   LEU A 209     -28.190 -32.167  -9.644  1.00 38.99           N  
ATOM   1595  CA  LEU A 209     -28.069 -33.566 -10.066  1.00 36.87           C  
ATOM   1596  C   LEU A 209     -27.157 -33.535 -11.286  1.00 35.94           C  
ATOM   1597  O   LEU A 209     -27.603 -33.262 -12.382  1.00 31.74           O  
ATOM   1598  CB  LEU A 209     -29.448 -34.146 -10.403  1.00 36.67           C  
ATOM   1599  CG  LEU A 209     -29.569 -35.626 -10.791  1.00 35.66           C  
ATOM   1600  CD1 LEU A 209     -28.835 -36.514  -9.805  1.00 36.25           C  
ATOM   1601  CD2 LEU A 209     -31.035 -36.029 -10.879  1.00 36.28           C  
ATOM   1602  N   VAL A 210     -25.864 -33.772 -11.054  1.00 38.15           N  
ATOM   1603  CA  VAL A 210     -24.838 -33.635 -12.079  1.00 38.29           C  
ATOM   1604  C   VAL A 210     -24.736 -34.956 -12.856  1.00 37.90           C  
ATOM   1605  O   VAL A 210     -24.741 -34.944 -14.094  1.00 37.70           O  
ATOM   1606  CB  VAL A 210     -23.495 -33.202 -11.434  1.00 40.31           C  
ATOM   1607  CG1 VAL A 210     -22.323 -33.316 -12.388  1.00 40.85           C  
ATOM   1608  CG2 VAL A 210     -23.612 -31.771 -10.936  1.00 41.07           C  
ATOM   1609  N   GLY A 211     -24.722 -36.074 -12.123  1.00 35.64           N  
ATOM   1610  CA  GLY A 211     -24.617 -37.424 -12.705  1.00 32.78           C  
ATOM   1611  C   GLY A 211     -25.700 -38.416 -12.277  1.00 34.22           C  
ATOM   1612  O   GLY A 211     -26.380 -38.209 -11.264  1.00 34.23           O  
ATOM   1613  N   ILE A 212     -25.877 -39.475 -13.078  1.00 32.86           N  
ATOM   1614  CA  ILE A 212     -26.614 -40.680 -12.684  1.00 32.95           C  
ATOM   1615  C   ILE A 212     -25.590 -41.791 -12.669  1.00 30.87           C  
ATOM   1616  O   ILE A 212     -24.899 -41.995 -13.657  1.00 32.33           O  
ATOM   1617  CB  ILE A 212     -27.741 -41.038 -13.671  1.00 33.16           C  
ATOM   1618  CG1 ILE A 212     -28.745 -39.897 -13.762  1.00 34.35           C  
ATOM   1619  CG2 ILE A 212     -28.422 -42.338 -13.253  1.00 34.99           C  
ATOM   1620  CD1 ILE A 212     -29.796 -40.058 -14.847  1.00 37.01           C  
ATOM   1621  N   THR A 213     -25.481 -42.488 -11.548  1.00 29.83           N  
ATOM   1622  CA  THR A 213     -24.542 -43.575 -11.386  1.00 32.67           C  
ATOM   1623  C   THR A 213     -24.786 -44.662 -12.420  1.00 32.49           C  
ATOM   1624  O   THR A 213     -25.893 -45.166 -12.551  1.00 32.39           O  
ATOM   1625  CB  THR A 213     -24.617 -44.168  -9.967  1.00 33.37           C  
ATOM   1626  OG1 THR A 213     -24.212 -43.174  -9.032  1.00 34.05           O  
ATOM   1627  CG2 THR A 213     -23.695 -45.326  -9.816  1.00 32.68           C  
ATOM   1628  N   SER A 214     -23.740 -45.007 -13.174  1.00 33.88           N  
ATOM   1629  CA  SER A 214     -23.942 -45.790 -14.398  1.00 31.51           C  
ATOM   1630  C   SER A 214     -23.037 -47.020 -14.524  1.00 29.25           C  
ATOM   1631  O   SER A 214     -23.524 -48.126 -14.478  1.00 30.29           O  
ATOM   1632  CB  SER A 214     -23.866 -44.879 -15.615  1.00 31.73           C  
ATOM   1633  OG  SER A 214     -23.822 -45.647 -16.803  1.00 34.98           O  
ATOM   1634  N   TRP A 215     -21.730 -46.838 -14.650  1.00 31.05           N  
ATOM   1635  CA  TRP A 215     -20.826 -47.981 -14.742  1.00 32.36           C  
ATOM   1636  C   TRP A 215     -19.384 -47.665 -14.354  1.00 33.14           C  
ATOM   1637  O   TRP A 215     -18.976 -46.509 -14.276  1.00 33.92           O  
ATOM   1638  CB  TRP A 215     -20.859 -48.572 -16.169  1.00 32.55           C  
ATOM   1639  CG  TRP A 215     -20.347 -47.656 -17.259  1.00 31.95           C  
ATOM   1640  CD1 TRP A 215     -21.039 -46.645 -17.866  1.00 31.22           C  
ATOM   1641  CD2 TRP A 215     -19.038 -47.670 -17.880  1.00 34.41           C  
ATOM   1642  NE1 TRP A 215     -20.247 -46.017 -18.802  1.00 33.50           N  
ATOM   1643  CE2 TRP A 215     -19.018 -46.627 -18.837  1.00 33.43           C  
ATOM   1644  CE3 TRP A 215     -17.884 -48.445 -17.704  1.00 35.36           C  
ATOM   1645  CZ2 TRP A 215     -17.894 -46.354 -19.630  1.00 35.70           C  
ATOM   1646  CZ3 TRP A 215     -16.767 -48.177 -18.490  1.00 34.84           C  
ATOM   1647  CH2 TRP A 215     -16.784 -47.151 -19.457  1.00 35.92           C  
ATOM   1648  N   GLY A 216     -18.621 -48.716 -14.111  1.00 30.87           N  
ATOM   1649  CA  GLY A 216     -17.169 -48.613 -13.952  1.00 31.36           C  
ATOM   1650  C   GLY A 216     -16.526 -49.985 -14.126  1.00 31.43           C  
ATOM   1651  O   GLY A 216     -17.234 -51.003 -14.147  1.00 31.95           O  
ATOM   1652  N   GLU A 217     -15.199 -50.030 -14.241  1.00 32.26           N  
ATOM   1653  CA  GLU A 217     -14.498 -51.316 -14.212  1.00 32.45           C  
ATOM   1654  C   GLU A 217     -14.189 -51.704 -12.767  1.00 32.02           C  
ATOM   1655  O   GLU A 217     -13.306 -51.132 -12.140  1.00 33.59           O  
ATOM   1656  CB  GLU A 217     -13.219 -51.276 -15.057  1.00 36.91           C  
ATOM   1657  CG  GLU A 217     -12.552 -52.639 -15.230  1.00 38.99           C  
ATOM   1658  CD  GLU A 217     -13.510 -53.689 -15.785  1.00 41.08           C  
ATOM   1659  OE1 GLU A 217     -13.971 -53.526 -16.925  1.00 44.63           O  
ATOM   1660  OE2 GLU A 217     -13.814 -54.666 -15.075  1.00 45.35           O  
ATOM   1661  N   GLY A 218     -14.920 -52.685 -12.251  1.00 30.79           N  
ATOM   1662  CA  GLY A 218     -14.907 -53.004 -10.839  1.00 33.44           C  
ATOM   1663  C   GLY A 218     -15.364 -51.782 -10.042  1.00 33.68           C  
ATOM   1664  O   GLY A 218     -15.904 -50.818 -10.620  1.00 30.04           O  
ATOM   1665  N   CYS A 219     -15.090 -51.803  -8.744  1.00 33.22           N  
ATOM   1666  CA  CYS A 219     -15.518 -50.734  -7.810  1.00 36.81           C  
ATOM   1667  C   CYS A 219     -14.339 -50.105  -7.063  1.00 34.89           C  
ATOM   1668  O   CYS A 219     -13.611 -50.801  -6.414  1.00 34.32           O  
ATOM   1669  CB  CYS A 219     -16.467 -51.343  -6.779  1.00 36.43           C  
ATOM   1670  SG  CYS A 219     -17.910 -52.132  -7.500  1.00 43.39           S  
ATOM   1671  N   ALA A 220     -14.137 -48.796  -7.181  1.00 38.05           N  
ATOM   1672  CA  ALA A 220     -13.144 -48.084  -6.353  1.00 41.06           C  
ATOM   1673  C   ALA A 220     -11.670 -48.487  -6.582  1.00 42.41           C  
ATOM   1674  O   ALA A 220     -10.821 -48.273  -5.701  1.00 37.46           O  
ATOM   1675  CB  ALA A 220     -13.481 -48.206  -4.860  1.00 41.37           C  
ATOM   1676  N   GLN A 221     -11.379 -49.028  -7.761  1.00 43.24           N  
ATOM   1677  CA  GLN A 221     -10.015 -49.446  -8.118  1.00 42.09           C  
ATOM   1678  C   GLN A 221      -9.163 -48.251  -8.485  1.00 39.10           C  
ATOM   1679  O   GLN A 221      -9.654 -47.285  -9.037  1.00 37.67           O  
ATOM   1680  CB  GLN A 221     -10.048 -50.420  -9.297  1.00 41.82           C  
ATOM   1681  CG  GLN A 221     -10.646 -51.770  -8.958  1.00 41.31           C  
ATOM   1682  CD  GLN A 221     -10.367 -52.798 -10.037  1.00 44.75           C  
ATOM   1683  OE1 GLN A 221      -9.571 -53.731  -9.838  1.00 42.63           O  
ATOM   1684  NE2 GLN A 221     -11.000 -52.623 -11.200  1.00 40.23           N  
ATOM   1685  N   ARG A 222      -7.866 -48.315  -8.218  1.00 44.51           N  
ATOM   1686  CA  ARG A 222      -7.005 -47.187  -8.622  1.00 42.88           C  
ATOM   1687  C   ARG A 222      -7.061 -47.033 -10.140  1.00 39.28           C  
ATOM   1688  O   ARG A 222      -7.250 -48.006 -10.850  1.00 40.36           O  
ATOM   1689  CB  ARG A 222      -5.567 -47.326  -8.095  1.00 45.52           C  
ATOM   1690  CG  ARG A 222      -4.681 -48.355  -8.766  1.00 51.96           C  
ATOM   1691  CD  ARG A 222      -3.283 -48.363  -8.139  1.00 56.25           C  
ATOM   1692  NE  ARG A 222      -2.335 -47.536  -8.884  1.00 56.80           N  
ATOM   1693  CZ  ARG A 222      -1.754 -47.900 -10.033  1.00 67.88           C  
ATOM   1694  NH1 ARG A 222      -2.022 -49.077 -10.601  1.00 68.55           N  
ATOM   1695  NH2 ARG A 222      -0.895 -47.079 -10.634  1.00 71.45           N  
ATOM   1696  N   GLU A 223      -6.966 -45.795 -10.598  1.00 40.06           N  
ATOM   1697  CA  GLU A 223      -7.067 -45.419 -12.006  1.00 45.62           C  
ATOM   1698  C   GLU A 223      -8.333 -45.908 -12.783  1.00 45.40           C  
ATOM   1699  O   GLU A 223      -8.292 -46.070 -14.009  1.00 41.77           O  
ATOM   1700  CB  GLU A 223      -5.743 -45.795 -12.709  1.00 49.83           C  
ATOM   1701  CG  GLU A 223      -4.614 -44.848 -12.287  1.00 52.38           C  
ATOM   1702  CD  GLU A 223      -3.207 -45.305 -12.658  1.00 57.52           C  
ATOM   1703  OE1 GLU A 223      -3.022 -46.233 -13.482  1.00 56.91           O  
ATOM   1704  OE2 GLU A 223      -2.262 -44.689 -12.121  1.00 63.20           O  
ATOM   1705  N   ARG A 224      -9.449 -46.116 -12.072  1.00 40.43           N  
ATOM   1706  CA  ARG A 224     -10.733 -46.465 -12.702  1.00 37.12           C  
ATOM   1707  C   ARG A 224     -11.836 -45.617 -12.119  1.00 37.15           C  
ATOM   1708  O   ARG A 224     -12.588 -46.045 -11.229  1.00 32.24           O  
ATOM   1709  CB  ARG A 224     -11.067 -47.925 -12.487  1.00 35.11           C  
ATOM   1710  CG  ARG A 224     -10.116 -48.897 -13.181  1.00 36.24           C  
ATOM   1711  CD  ARG A 224     -10.149 -48.771 -14.693  1.00 35.93           C  
ATOM   1712  NE  ARG A 224      -9.526 -49.939 -15.328  1.00 36.66           N  
ATOM   1713  CZ  ARG A 224      -9.649 -50.276 -16.616  1.00 37.38           C  
ATOM   1714  NH1 ARG A 224     -10.377 -49.525 -17.473  1.00 34.12           N  
ATOM   1715  NH2 ARG A 224      -9.052 -51.386 -17.051  1.00 36.11           N  
ATOM   1716  N   PRO A 225     -11.938 -44.391 -12.598  1.00 35.76           N  
ATOM   1717  CA  PRO A 225     -13.027 -43.576 -12.070  1.00 35.18           C  
ATOM   1718  C   PRO A 225     -14.388 -44.201 -12.328  1.00 37.03           C  
ATOM   1719  O   PRO A 225     -14.537 -45.053 -13.204  1.00 36.88           O  
ATOM   1720  CB  PRO A 225     -12.867 -42.234 -12.793  1.00 36.14           C  
ATOM   1721  CG  PRO A 225     -11.874 -42.456 -13.883  1.00 35.68           C  
ATOM   1722  CD  PRO A 225     -11.028 -43.639 -13.474  1.00 37.27           C  
ATOM   1723  N   GLY A 226     -15.359 -43.829 -11.508  1.00 34.80           N  
ATOM   1724  CA  GLY A 226     -16.748 -44.150 -11.785  1.00 36.03           C  
ATOM   1725  C   GLY A 226     -17.204 -43.348 -12.997  1.00 34.54           C  
ATOM   1726  O   GLY A 226     -16.765 -42.210 -13.169  1.00 33.29           O  
ATOM   1727  N   VAL A 227     -18.088 -43.928 -13.819  1.00 31.14           N  
ATOM   1728  CA  VAL A 227     -18.680 -43.210 -14.959  1.00 29.57           C  
ATOM   1729  C   VAL A 227     -20.175 -42.965 -14.753  1.00 30.12           C  
ATOM   1730  O   VAL A 227     -20.931 -43.872 -14.398  1.00 30.83           O  
ATOM   1731  CB  VAL A 227     -18.468 -43.963 -16.295  1.00 30.55           C  
ATOM   1732  CG1 VAL A 227     -18.970 -43.122 -17.470  1.00 29.78           C  
ATOM   1733  CG2 VAL A 227     -17.000 -44.328 -16.482  1.00 30.33           C  
ATOM   1734  N   TYR A 228     -20.593 -41.734 -15.024  1.00 31.64           N  
ATOM   1735  CA  TYR A 228     -21.949 -41.262 -14.715  1.00 34.00           C  
ATOM   1736  C   TYR A 228     -22.546 -40.626 -15.945  1.00 31.51           C  
ATOM   1737  O   TYR A 228     -21.835 -40.006 -16.721  1.00 33.67           O  
ATOM   1738  CB  TYR A 228     -21.921 -40.202 -13.585  1.00 32.31           C  
ATOM   1739  CG  TYR A 228     -21.358 -40.708 -12.277  1.00 32.35           C  
ATOM   1740  CD1 TYR A 228     -19.987 -40.838 -12.077  1.00 31.17           C  
ATOM   1741  CD2 TYR A 228     -22.204 -41.079 -11.242  1.00 31.27           C  
ATOM   1742  CE1 TYR A 228     -19.486 -41.316 -10.881  1.00 29.87           C  
ATOM   1743  CE2 TYR A 228     -21.702 -41.564 -10.059  1.00 29.52           C  
ATOM   1744  CZ  TYR A 228     -20.359 -41.672  -9.884  1.00 29.64           C  
ATOM   1745  OH  TYR A 228     -19.927 -42.162  -8.699  1.00 32.18           O  
ATOM   1746  N   THR A 229     -23.857 -40.757 -16.103  1.00 31.41           N  
ATOM   1747  CA  THR A 229     -24.554 -40.084 -17.180  1.00 33.45           C  
ATOM   1748  C   THR A 229     -24.512 -38.584 -16.879  1.00 35.95           C  
ATOM   1749  O   THR A 229     -24.818 -38.166 -15.758  1.00 33.35           O  
ATOM   1750  CB  THR A 229     -26.022 -40.558 -17.262  1.00 35.03           C  
ATOM   1751  OG1 THR A 229     -26.066 -41.958 -17.532  1.00 31.97           O  
ATOM   1752  CG2 THR A 229     -26.804 -39.803 -18.340  1.00 33.52           C  
ATOM   1753  N   ASN A 230     -24.132 -37.786 -17.871  1.00 35.83           N  
ATOM   1754  CA  ASN A 230     -23.959 -36.356 -17.703  1.00 38.72           C  
ATOM   1755  C   ASN A 230     -25.289 -35.600 -17.874  1.00 35.21           C  
ATOM   1756  O   ASN A 230     -25.724 -35.270 -18.981  1.00 33.89           O  
ATOM   1757  CB  ASN A 230     -22.889 -35.858 -18.683  1.00 41.69           C  
ATOM   1758  CG  ASN A 230     -22.468 -34.426 -18.420  1.00 43.40           C  
ATOM   1759  OD1 ASN A 230     -22.723 -33.871 -17.357  1.00 40.56           O  
ATOM   1760  ND2 ASN A 230     -21.839 -33.820 -19.406  1.00 45.45           N  
ATOM   1761  N   VAL A 231     -25.933 -35.326 -16.754  1.00 36.15           N  
ATOM   1762  CA  VAL A 231     -27.338 -34.943 -16.758  1.00 35.59           C  
ATOM   1763  C   VAL A 231     -27.618 -33.671 -17.551  1.00 37.71           C  
ATOM   1764  O   VAL A 231     -28.651 -33.586 -18.246  1.00 34.40           O  
ATOM   1765  CB  VAL A 231     -27.879 -34.861 -15.327  1.00 36.32           C  
ATOM   1766  CG1 VAL A 231     -29.280 -34.289 -15.293  1.00 36.99           C  
ATOM   1767  CG2 VAL A 231     -27.879 -36.258 -14.696  1.00 35.28           C  
ATOM   1768  N   VAL A 232     -26.689 -32.712 -17.521  1.00 39.06           N  
ATOM   1769  CA  VAL A 232     -26.944 -31.431 -18.198  1.00 39.75           C  
ATOM   1770  C   VAL A 232     -27.164 -31.628 -19.703  1.00 41.50           C  
ATOM   1771  O   VAL A 232     -27.879 -30.848 -20.350  1.00 41.49           O  
ATOM   1772  CB  VAL A 232     -25.845 -30.383 -17.900  1.00 42.34           C  
ATOM   1773  CG1 VAL A 232     -24.481 -30.795 -18.452  1.00 43.99           C  
ATOM   1774  CG2 VAL A 232     -26.263 -29.015 -18.424  1.00 44.29           C  
ATOM   1775  N   GLU A 233     -26.575 -32.689 -20.244  1.00 36.48           N  
ATOM   1776  CA  GLU A 233     -26.756 -33.026 -21.645  1.00 38.87           C  
ATOM   1777  C   GLU A 233     -28.146 -33.536 -22.007  1.00 37.12           C  
ATOM   1778  O   GLU A 233     -28.445 -33.680 -23.177  1.00 36.79           O  
ATOM   1779  CB  GLU A 233     -25.678 -34.049 -22.090  1.00 41.51           C  
ATOM   1780  CG  GLU A 233     -24.306 -33.434 -22.291  1.00 42.20           C  
ATOM   1781  CD  GLU A 233     -24.278 -32.442 -23.467  1.00 49.90           C  
ATOM   1782  OE1 GLU A 233     -24.617 -32.849 -24.613  1.00 51.03           O  
ATOM   1783  OE2 GLU A 233     -23.901 -31.262 -23.243  1.00 49.30           O  
ATOM   1784  N   TYR A 234     -28.990 -33.817 -21.019  1.00 36.46           N  
ATOM   1785  CA  TYR A 234     -30.292 -34.438 -21.266  1.00 35.50           C  
ATOM   1786  C   TYR A 234     -31.472 -33.566 -20.839  1.00 38.61           C  
ATOM   1787  O   TYR A 234     -32.608 -34.040 -20.787  1.00 42.40           O  
ATOM   1788  CB  TYR A 234     -30.348 -35.810 -20.553  1.00 35.42           C  
ATOM   1789  CG  TYR A 234     -29.386 -36.804 -21.164  1.00 34.13           C  
ATOM   1790  CD1 TYR A 234     -29.723 -37.509 -22.311  1.00 33.37           C  
ATOM   1791  CD2 TYR A 234     -28.126 -36.989 -20.633  1.00 35.92           C  
ATOM   1792  CE1 TYR A 234     -28.843 -38.388 -22.900  1.00 31.76           C  
ATOM   1793  CE2 TYR A 234     -27.237 -37.874 -21.205  1.00 35.68           C  
ATOM   1794  CZ  TYR A 234     -27.592 -38.570 -22.351  1.00 34.44           C  
ATOM   1795  OH  TYR A 234     -26.691 -39.464 -22.922  1.00 31.77           O  
ATOM   1796  N   VAL A 235     -31.230 -32.293 -20.549  1.00 40.46           N  
ATOM   1797  CA  VAL A 235     -32.312 -31.438 -20.038  1.00 41.47           C  
ATOM   1798  C   VAL A 235     -33.415 -31.233 -21.056  1.00 39.89           C  
ATOM   1799  O   VAL A 235     -34.575 -31.169 -20.681  1.00 40.47           O  
ATOM   1800  CB  VAL A 235     -31.823 -30.075 -19.502  1.00 42.94           C  
ATOM   1801  CG1 VAL A 235     -30.822 -30.287 -18.378  1.00 44.53           C  
ATOM   1802  CG2 VAL A 235     -31.233 -29.206 -20.611  1.00 44.62           C  
ATOM   1803  N   ASP A 236     -33.069 -31.152 -22.337  1.00 40.35           N  
ATOM   1804  CA  ASP A 236     -34.095 -31.109 -23.395  1.00 42.38           C  
ATOM   1805  C   ASP A 236     -34.924 -32.390 -23.393  1.00 41.25           C  
ATOM   1806  O   ASP A 236     -36.160 -32.350 -23.447  1.00 42.14           O  
ATOM   1807  CB  ASP A 236     -33.470 -30.947 -24.788  1.00 45.08           C  
ATOM   1808  CG  ASP A 236     -32.859 -29.568 -25.004  1.00 47.98           C  
ATOM   1809  OD1 ASP A 236     -33.309 -28.594 -24.369  1.00 50.68           O  
ATOM   1810  OD2 ASP A 236     -31.914 -29.454 -25.809  1.00 50.31           O  
ATOM   1811  N   TRP A 237     -34.230 -33.522 -23.335  1.00 35.87           N  
ATOM   1812  CA  TRP A 237     -34.900 -34.815 -23.323  1.00 38.15           C  
ATOM   1813  C   TRP A 237     -35.821 -34.953 -22.084  1.00 36.17           C  
ATOM   1814  O   TRP A 237     -36.952 -35.401 -22.192  1.00 38.11           O  
ATOM   1815  CB  TRP A 237     -33.869 -35.957 -23.389  1.00 39.40           C  
ATOM   1816  CG  TRP A 237     -34.499 -37.329 -23.457  1.00 38.95           C  
ATOM   1817  CD1 TRP A 237     -34.929 -37.973 -24.579  1.00 41.28           C  
ATOM   1818  CD2 TRP A 237     -34.769 -38.205 -22.367  1.00 39.66           C  
ATOM   1819  NE1 TRP A 237     -35.461 -39.190 -24.260  1.00 40.91           N  
ATOM   1820  CE2 TRP A 237     -35.370 -39.370 -22.906  1.00 42.29           C  
ATOM   1821  CE3 TRP A 237     -34.552 -38.135 -20.989  1.00 40.35           C  
ATOM   1822  CZ2 TRP A 237     -35.769 -40.458 -22.107  1.00 42.12           C  
ATOM   1823  CZ3 TRP A 237     -34.940 -39.228 -20.188  1.00 41.82           C  
ATOM   1824  CH2 TRP A 237     -35.543 -40.371 -20.755  1.00 40.91           C  
ATOM   1825  N   ILE A 238     -35.338 -34.555 -20.919  1.00 36.60           N  
ATOM   1826  CA  ILE A 238     -36.150 -34.618 -19.708  1.00 39.40           C  
ATOM   1827  C   ILE A 238     -37.408 -33.770 -19.904  1.00 41.79           C  
ATOM   1828  O   ILE A 238     -38.530 -34.242 -19.696  1.00 40.75           O  
ATOM   1829  CB  ILE A 238     -35.346 -34.179 -18.462  1.00 40.24           C  
ATOM   1830  CG1 ILE A 238     -34.301 -35.251 -18.125  1.00 39.41           C  
ATOM   1831  CG2 ILE A 238     -36.255 -33.981 -17.244  1.00 40.88           C  
ATOM   1832  CD1 ILE A 238     -33.192 -34.810 -17.192  1.00 38.97           C  
ATOM   1833  N   LEU A 239     -37.229 -32.533 -20.361  1.00 44.46           N  
ATOM   1834  CA  LEU A 239     -38.377 -31.643 -20.616  1.00 44.87           C  
ATOM   1835  C   LEU A 239     -39.387 -32.261 -21.586  1.00 44.23           C  
ATOM   1836  O   LEU A 239     -40.581 -32.285 -21.304  1.00 48.70           O  
ATOM   1837  CB  LEU A 239     -37.907 -30.275 -21.130  1.00 41.63           C  
ATOM   1838  CG  LEU A 239     -39.004 -29.274 -21.558  1.00 44.82           C  
ATOM   1839  CD1 LEU A 239     -40.054 -29.039 -20.474  1.00 41.57           C  
ATOM   1840  CD2 LEU A 239     -38.385 -27.947 -21.981  1.00 43.94           C  
ATOM   1841  N   GLU A 240     -38.901 -32.761 -22.721  1.00 45.34           N  
ATOM   1842  CA  GLU A 240     -39.767 -33.380 -23.729  1.00 49.79           C  
ATOM   1843  C   GLU A 240     -40.610 -34.496 -23.106  1.00 49.88           C  
ATOM   1844  O   GLU A 240     -41.827 -34.488 -23.202  1.00 47.51           O  
ATOM   1845  CB  GLU A 240     -38.918 -33.940 -24.884  1.00 57.21           C  
ATOM   1846  CG  GLU A 240     -39.682 -34.771 -25.916  1.00 63.94           C  
ATOM   1847  CD  GLU A 240     -38.810 -35.803 -26.644  1.00 71.13           C  
ATOM   1848  OE1 GLU A 240     -37.609 -35.543 -26.868  1.00 74.37           O  
ATOM   1849  OE2 GLU A 240     -39.333 -36.886 -27.003  1.00 77.02           O  
ATOM   1850  N   LYS A 241     -39.951 -35.438 -22.436  1.00 50.51           N  
ATOM   1851  CA  LYS A 241     -40.624 -36.637 -21.923  1.00 48.89           C  
ATOM   1852  C   LYS A 241     -41.534 -36.410 -20.721  1.00 52.19           C  
ATOM   1853  O   LYS A 241     -42.528 -37.109 -20.574  1.00 58.35           O  
ATOM   1854  CB  LYS A 241     -39.601 -37.725 -21.599  1.00 49.44           C  
ATOM   1855  CG  LYS A 241     -38.859 -38.245 -22.818  1.00 50.62           C  
ATOM   1856  CD  LYS A 241     -39.827 -38.849 -23.820  1.00 51.39           C  
ATOM   1857  CE  LYS A 241     -39.116 -39.621 -24.909  1.00 51.55           C  
ATOM   1858  NZ  LYS A 241     -40.096 -39.937 -25.983  1.00 52.36           N  
ATOM   1859  N   THR A 242     -41.222 -35.431 -19.879  1.00 51.51           N  
ATOM   1860  CA  THR A 242     -42.030 -35.173 -18.689  1.00 51.08           C  
ATOM   1861  C   THR A 242     -43.319 -34.347 -18.955  1.00 56.59           C  
ATOM   1862  O   THR A 242     -44.061 -34.038 -18.029  1.00 56.46           O  
ATOM   1863  CB  THR A 242     -41.166 -34.555 -17.572  1.00 45.87           C  
ATOM   1864  OG1 THR A 242     -40.496 -33.400 -18.062  1.00 41.22           O  
ATOM   1865  CG2 THR A 242     -40.111 -35.557 -17.099  1.00 45.40           C  
ATOM   1866  N   GLN A 243     -43.596 -34.023 -20.218  1.00 64.12           N  
ATOM   1867  CA  GLN A 243     -44.889 -33.430 -20.626  1.00 65.36           C  
ATOM   1868  C   GLN A 243     -46.126 -34.284 -20.328  1.00 69.18           C  
ATOM   1869  O   GLN A 243     -46.062 -35.507 -20.248  1.00 74.59           O  
ATOM   1870  CB  GLN A 243     -44.877 -33.101 -22.123  1.00 65.88           C  
ATOM   1871  CG  GLN A 243     -43.850 -32.063 -22.533  1.00 67.05           C  
ATOM   1872  CD  GLN A 243     -43.881 -30.798 -21.680  1.00 72.76           C  
ATOM   1873  OE1 GLN A 243     -44.265 -29.730 -22.156  1.00 76.34           O  
ATOM   1874  NE2 GLN A 243     -43.455 -30.905 -20.422  1.00 73.12           N  
TER    1875      GLN A 243                                                      
HETATM 1876  C1  OTJ A1244     -28.720 -54.642  -7.994  1.00 32.23           C  
HETATM 1877  C2  OTJ A1244     -27.081 -56.142  -7.126  1.00 33.50           C  
HETATM 1878  C3  OTJ A1244     -18.665 -48.745 -10.531  1.00 31.88           C  
HETATM 1879  C4  OTJ A1244     -29.581 -55.011  -6.985  1.00 30.21           C  
HETATM 1880  C5  OTJ A1244     -27.934 -56.519  -6.089  1.00 31.72           C  
HETATM 1881  C6  OTJ A1244     -18.788 -47.369 -10.648  1.00 33.98           C  
HETATM 1882  C7  OTJ A1244     -21.090 -47.615 -11.312  1.00 33.42           C  
HETATM 1883  C8  OTJ A1244     -18.711 -51.695 -11.367  1.00 30.52           C  
HETATM 1884  C9  OTJ A1244     -27.465 -55.214  -8.086  1.00 32.07           C  
HETATM 1885  C10 OTJ A1244     -20.990 -48.990 -11.210  1.00 32.69           C  
HETATM 1886  C11 OTJ A1244     -19.772 -49.522 -10.819  1.00 32.49           C  
HETATM 1887  C12 OTJ A1244     -29.201 -55.947  -6.045  1.00 32.62           C  
HETATM 1888  C13 OTJ A1244     -19.997 -46.815 -11.034  1.00 31.31           C  
HETATM 1889  C14 OTJ A1244     -26.617 -54.802  -9.210  1.00 32.24           C  
HETATM 1890  C15 OTJ A1244     -25.613 -55.530  -9.805  1.00 33.86           C  
HETATM 1891  C16 OTJ A1244     -25.802 -53.597 -10.805  1.00 35.51           C  
HETATM 1892  C17 OTJ A1244     -24.257 -50.904 -10.380  1.00 35.16           C  
HETATM 1893  C18 OTJ A1244     -30.115 -57.288  -4.179  1.00 33.52           C  
HETATM 1894  C19 OTJ A1244     -31.104 -58.085  -2.257  1.00 33.84           C  
HETATM 1895  C20 OTJ A1244     -22.207 -49.826 -11.527  1.00 33.04           C  
HETATM 1896  C21 OTJ A1244     -25.501 -52.535 -11.784  1.00 31.82           C  
HETATM 1897  C22 OTJ A1244     -22.982 -50.093 -10.239  1.00 33.52           C  
HETATM 1898  N23 OTJ A1244     -18.820 -52.922 -10.918  1.00 29.64           N  
HETATM 1899  N24 OTJ A1244     -26.723 -53.594  -9.851  1.00 32.48           N  
HETATM 1900  N25 OTJ A1244     -19.806 -52.912  -9.962  1.00 29.73           N  
HETATM 1901  N26 OTJ A1244     -20.287 -51.672  -9.836  1.00 31.10           N  
HETATM 1902  N27 OTJ A1244     -25.105 -54.771 -10.805  1.00 33.50           N  
HETATM 1903  N28 OTJ A1244     -19.611 -50.915 -10.702  1.00 32.16           N  
HETATM 1904  N29 OTJ A1244     -30.166 -56.228  -5.058  1.00 33.41           N  
HETATM 1905  N30 OTJ A1244     -24.291 -51.777 -11.437  1.00 34.96           N  
HETATM 1906  O31 OTJ A1244     -25.177 -50.817  -9.569  1.00 32.74           O  
HETATM 1907  O32 OTJ A1244     -29.190 -58.085  -4.023  1.00 33.74           O  
HETATM 1908  O33 OTJ A1244     -31.254 -57.307  -3.453  1.00 30.79           O  
HETATM 1909 CL3  OTJ A1244     -20.153 -45.105 -11.175  1.00 33.52          CL  
HETATM 1910 CL5  OTJ A1244     -24.951 -57.106  -9.501  1.00 44.29          CL  
HETATM 1911  S   SO4 A1245     -26.869 -26.869 -26.869  0.33 59.18           S  
HETATM 1912  O1  SO4 A1245     -26.020 -26.020 -26.020  0.33 63.96           O  
HETATM 1913  O2  SO4 A1245     -26.271 -26.943 -28.219  0.33 61.74           O  
HETATM 1914  O3  SO4 A1245     -26.937 -28.219 -26.272  0.33 61.74           O  
HETATM 1915  O4  SO4 A1245     -28.221 -26.282 -26.945  0.33 61.73           O  
HETATM 1916  S   SO4 A1246      -6.925 -37.490  -6.206  1.00 78.75           S  
HETATM 1917  O1  SO4 A1246      -7.665 -36.709  -5.174  1.00 78.42           O  
HETATM 1918  O2  SO4 A1246      -5.768 -36.687  -6.692  1.00 82.76           O  
HETATM 1919  O3  SO4 A1246      -7.838 -37.777  -7.335  1.00 90.76           O  
HETATM 1920  O4  SO4 A1246      -6.467 -38.790  -5.638  1.00 79.78           O  
HETATM 1921  S   SO4 A1247     -18.155 -18.155 -18.155  0.33102.60           S  
HETATM 1922  O1  SO4 A1247     -17.300 -17.300 -17.300  0.33102.14           O  
HETATM 1923  O2  SO4 A1247     -17.301 -19.088 -18.928  0.33115.99           O  
HETATM 1924  O3  SO4 A1247     -18.925 -17.298 -19.088  0.33115.43           O  
HETATM 1925  O4  SO4 A1247     -19.092 -18.925 -17.304  0.33101.41           O  
HETATM 1926  O   HOH A2001     -23.827 -48.681   0.058  1.00 28.17           O  
HETATM 1927  O   HOH A2002     -15.931 -49.825   2.042  1.00 36.60           O  
HETATM 1928  O   HOH A2003     -32.918 -40.900  12.795  1.00 36.08           O  
HETATM 1929  O   HOH A2004     -36.557 -39.614  -0.849  1.00 31.86           O  
HETATM 1930  O   HOH A2005     -35.824 -43.309  -0.281  1.00 37.02           O  
HETATM 1931  O   HOH A2006     -28.026 -45.169  -5.500  1.00 29.10           O  
HETATM 1932  O   HOH A2007     -37.610 -57.592 -12.019  1.00 43.79           O  
HETATM 1933  O   HOH A2008     -34.929 -61.620  -4.797  1.00 38.08           O  
HETATM 1934  O   HOH A2009     -41.789 -60.893  -1.225  1.00 52.88           O  
HETATM 1935  O   HOH A2010     -43.779 -57.459  -2.570  1.00 40.18           O  
HETATM 1936  O   HOH A2011     -33.617 -55.733  -0.602  1.00 32.01           O  
HETATM 1937  O   HOH A2012     -28.838 -47.569  -4.152  1.00 31.31           O  
HETATM 1938  O   HOH A2013     -28.322 -51.246  -9.260  1.00 27.41           O  
HETATM 1939  O   HOH A2014     -30.774 -40.400 -10.282  1.00 24.48           O  
HETATM 1940  O   HOH A2015     -36.190 -31.216 -10.571  1.00 37.82           O  
HETATM 1941  O   HOH A2016     -51.144 -39.517 -14.859  1.00 38.13           O  
HETATM 1942  O   HOH A2017     -33.438 -51.685 -19.877  1.00 35.50           O  
HETATM 1943  O   HOH A2018     -28.716 -54.257 -16.378  1.00 36.94           O  
HETATM 1944  O   HOH A2019     -33.384 -55.513 -14.103  1.00 35.53           O  
HETATM 1945  O   HOH A2020     -34.805 -56.224 -21.281  1.00 43.01           O  
HETATM 1946  O   HOH A2021     -45.856 -50.354 -10.114  1.00 36.74           O  
HETATM 1947  O   HOH A2022     -46.805 -54.039  -5.763  1.00 54.84           O  
HETATM 1948  O   HOH A2023     -44.277 -52.193   1.001  1.00 36.24           O  
HETATM 1949  O   HOH A2024     -42.128 -44.448   0.057  1.00 41.60           O  
HETATM 1950  O   HOH A2025     -36.712 -54.601   3.607  1.00 35.22           O  
HETATM 1951  O   HOH A2026     -41.105 -48.513   8.594  1.00 42.31           O  
HETATM 1952  O   HOH A2027     -48.443 -47.550   4.782  1.00 42.08           O  
HETATM 1953  O   HOH A2028     -47.571 -43.761  -1.364  1.00 48.00           O  
HETATM 1954  O   HOH A2029     -25.255 -53.289 -15.907  1.00 53.20           O  
HETATM 1955  O   HOH A2030     -44.131 -48.468 -19.166  1.00 34.82           O  
HETATM 1956  O   HOH A2031      -3.447 -51.091  -6.547  1.00 38.12           O  
HETATM 1957  O   HOH A2032     -31.537 -36.538 -26.352  1.00 46.00           O  
HETATM 1958  O   HOH A2033     -36.151 -41.036 -26.160  1.00 37.39           O  
HETATM 1959  O   HOH A2034     -25.654 -45.725 -27.896  1.00 36.07           O  
HETATM 1960  O   HOH A2035     -25.832 -52.047 -19.620  1.00 39.04           O  
HETATM 1961  O   HOH A2036     -26.389 -47.007 -25.115  1.00 31.99           O  
HETATM 1962  O   HOH A2037     -22.756 -51.546 -20.840  1.00 38.96           O  
HETATM 1963  O   HOH A2038     -23.039 -44.455 -19.300  1.00 36.50           O  
HETATM 1964  O   HOH A2039     -23.804 -49.831 -27.877  1.00 40.03           O  
HETATM 1965  O   HOH A2040     -24.876 -42.488 -19.794  1.00 32.64           O  
HETATM 1966  O   HOH A2041     -24.785 -40.614 -21.590  1.00 30.99           O  
HETATM 1967  O   HOH A2042     -49.173 -50.745 -10.729  1.00 61.18           O  
HETATM 1968  O   HOH A2043     -50.823 -47.539 -13.532  1.00 48.16           O  
HETATM 1969  O   HOH A2044     -49.099 -42.176  -3.094  1.00 45.37           O  
HETATM 1970  O   HOH A2045     -46.208 -31.541  -2.990  1.00 43.69           O  
HETATM 1971  O   HOH A2046     -41.393 -31.915   6.498  1.00 40.13           O  
HETATM 1972  O   HOH A2047     -46.415 -38.793   0.134  1.00 42.96           O  
HETATM 1973  O   HOH A2048     -34.116 -30.529   1.966  1.00 49.67           O  
HETATM 1974  O   HOH A2049     -31.648 -29.064  -5.338  1.00 39.11           O  
HETATM 1975  O   HOH A2050     -30.368 -27.785  -2.282  1.00 48.85           O  
HETATM 1976  O   HOH A2051     -25.694 -38.098  -4.050  1.00 35.46           O  
HETATM 1977  O   HOH A2052     -25.813 -42.855  -6.689  1.00 34.65           O  
HETATM 1978  O   HOH A2053     -23.424 -60.058  -7.196  1.00 43.27           O  
HETATM 1979  O   HOH A2054     -21.918 -53.173   7.854  1.00 37.85           O  
HETATM 1980  O   HOH A2055     -14.412 -58.278  -3.416  1.00 36.33           O  
HETATM 1981  O   HOH A2056     -20.387 -54.871   4.487  1.00 38.43           O  
HETATM 1982  O   HOH A2057     -27.614 -58.277  -1.648  1.00 39.70           O  
HETATM 1983  O   HOH A2058     -32.247 -50.624  10.835  1.00 43.20           O  
HETATM 1984  O   HOH A2059     -27.572 -51.369   9.855  1.00 54.57           O  
HETATM 1985  O   HOH A2060     -16.524 -39.101   1.769  1.00 37.05           O  
HETATM 1986  O   HOH A2061     -11.437 -49.397 -21.102  1.00 44.92           O  
HETATM 1987  O   HOH A2062     -22.945 -41.167 -24.655  1.00 47.40           O  
HETATM 1988  O   HOH A2063     -28.582 -35.894 -25.274  1.00 44.73           O  
HETATM 1989  O   HOH A2064     -11.941 -43.613  -6.374  1.00 37.52           O  
HETATM 1990  O   HOH A2065     -11.940 -47.688   0.454  1.00 43.40           O  
HETATM 1991  O   HOH A2066     -15.039 -47.399 -11.075  1.00 39.30           O  
HETATM 1992  O   HOH A2067     -26.825 -30.017   2.890  1.00 58.88           O  
HETATM 1993  O   HOH A2068     -24.466 -32.722 -15.755  1.00 37.78           O  
HETATM 1994  O   HOH A2069     -23.380 -51.022 -14.752  1.00 36.68           O  
HETATM 1995  O   HOH A2070     -20.427 -51.504 -14.250  1.00 34.65           O  
HETATM 1996  O   HOH A2071     -13.094 -49.164 -10.023  1.00 34.03           O  
HETATM 1997  O   HOH A2072     -12.043 -45.728  -8.448  1.00 35.55           O  
HETATM 1998  O   HOH A2073      -7.137 -50.845  -6.726  1.00 38.24           O  
HETATM 1999  O   HOH A2074      -6.933 -50.471 -11.088  1.00 37.03           O  
HETATM 2000  O   HOH A2075      -2.216 -45.139  -7.131  1.00 51.74           O  
HETATM 2001  O   HOH A2076     -30.206 -31.010 -23.749  1.00 40.39           O  
CONECT  226  346                                                                
CONECT  232  346                                                                
CONECT  346  226  232                                                           
CONECT  997 1526                                                                
CONECT 1256 1387                                                                
CONECT 1387 1256                                                                
CONECT 1464 1670                                                                
CONECT 1526  997                                                                
CONECT 1670 1464                                                                
CONECT 1876 1879 1884                                                           
CONECT 1877 1880 1884                                                           
CONECT 1878 1881 1886                                                           
CONECT 1879 1876 1887                                                           
CONECT 1880 1877 1887                                                           
CONECT 1881 1878 1888                                                           
CONECT 1882 1885 1888                                                           
CONECT 1883 1898 1903                                                           
CONECT 1884 1876 1877 1889                                                      
CONECT 1885 1882 1886 1895                                                      
CONECT 1886 1878 1885 1903                                                      
CONECT 1887 1879 1880 1904                                                      
CONECT 1888 1881 1882 1909                                                      
CONECT 1889 1884 1890 1899                                                      
CONECT 1890 1889 1902 1910                                                      
CONECT 1891 1896 1899 1902                                                      
CONECT 1892 1897 1905 1906                                                      
CONECT 1893 1904 1907 1908                                                      
CONECT 1894 1908                                                                
CONECT 1895 1885 1897                                                           
CONECT 1896 1891 1905                                                           
CONECT 1897 1892 1895                                                           
CONECT 1898 1883 1900                                                           
CONECT 1899 1889 1891                                                           
CONECT 1900 1898 1901                                                           
CONECT 1901 1900 1903                                                           
CONECT 1902 1890 1891                                                           
CONECT 1903 1883 1886 1901                                                      
CONECT 1904 1887 1893                                                           
CONECT 1905 1892 1896                                                           
CONECT 1906 1892                                                                
CONECT 1907 1893                                                                
CONECT 1908 1893 1894                                                           
CONECT 1909 1888                                                                
CONECT 1910 1890                                                                
CONECT 1911 1912 1913 1914 1915                                                 
CONECT 1912 1911                                                                
CONECT 1913 1911                                                                
CONECT 1914 1911                                                                
CONECT 1915 1911                                                                
CONECT 1916 1917 1918 1919 1920                                                 
CONECT 1917 1916                                                                
CONECT 1918 1916                                                                
CONECT 1919 1916                                                                
CONECT 1920 1916                                                                
CONECT 1921 1922 1923 1924 1925                                                 
CONECT 1922 1921                                                                
CONECT 1923 1921                                                                
CONECT 1924 1921                                                                
CONECT 1925 1921                                                                
MASTER      441    0    4    7   15    0    9    6 2000    1   59   19          
END                                                                             
