HEADER    HYDROLASE                               26-FEB-14   4CRB              
TITLE     CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD              
TITLE    2 GENERATION AND STRUCTURE AIDED DRUG DESIGN                           
COMPND    MOL_ID: 1;                                                            
COMPND   2 MOLECULE: COAGULATION FACTOR XI;                                     
COMPND   3 CHAIN: A;                                                            
COMPND   4 FRAGMENT: CATALYTIC DOMAIN, RESIDUES 388-625;                        
COMPND   5 SYNONYM: FXI, PLASMA THROMBOPLASTIN ANTECEDENT, PTA, COAGULATION     
COMPND   6  FACTOR XIA LIGHT CHAIN;                                             
COMPND   7 EC: 3.4.21.27;                                                       
COMPND   8 ENGINEERED: YES;                                                     
COMPND   9 MUTATION: YES                                                        
SOURCE    MOL_ID: 1;                                                            
SOURCE   2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;                                   
SOURCE   3 ORGANISM_COMMON: HUMAN;                                              
SOURCE   4 ORGANISM_TAXID: 9606;                                                
SOURCE   5 EXPRESSION_SYSTEM: PICHIA PASTORIS;                                  
SOURCE   6 EXPRESSION_SYSTEM_TAXID: 4922                                        
KEYWDS    HYDROLASE                                                             
EXPDTA    X-RAY DIFFRACTION                                                     
AUTHOR    J.SANDMARK,L.OSTER,O.FJELLSTROM,S.AKKAYA,H.G.BEISEL,P.O.ERIKSSON,     
AUTHOR   2 K.ERIXON,D.GUSTAFSSON,U.JURVA,D.KANG,D.KARIS,W.KNECHT,V.NERME,       
AUTHOR   3 I.NILSSON,T.OLSSON,A.REDZIC,R.ROTH,A.TIGERSTROM                      
REVDAT   1   11-FEB-15 4CRB    0                                                
JRNL        AUTH   O.FJELLSTROM,S.AKKAYA,H.BEISEL,P.ERIKSSON,K.ERIXON,          
JRNL        AUTH 2 D.GUSTAFSSON,U.JURVA,D.KANG,D.KARIS,W.KNECHT,V.NERME,        
JRNL        AUTH 3 I.NILSSON,T.OLSSON,A.REDZIC,R.ROTH,J.SANDMARK,A.TIGERSTROM,  
JRNL        AUTH 4 L.OSTER                                                      
JRNL        TITL   CREATING NOVEL ACTIVATED FACTOR XI INHIBITORS THROUGH        
JRNL        TITL 2 FRAGMENT BASED LEAD GENERATION AND STRUCTURE AIDED DRUG      
JRNL        TITL 3 DESIGN.                                                      
JRNL        REF    PLOS ONE                      V.  10 13705 2015              
JRNL        REFN                   ISSN 1932-6203                               
JRNL        PMID   25629509                                                     
JRNL        DOI    10.1371/JOURNAL.PONE.0113705                                 
REMARK   2                                                                      
REMARK   2 RESOLUTION.    1.85 ANGSTROMS.                                       
REMARK   3                                                                      
REMARK   3 REFINEMENT.                                                          
REMARK   3   PROGRAM     : REFMAC 5.7.0029                                      
REMARK   3   AUTHORS     : MURSHUDOV,SKUBAK,LEBEDEV,PANNU,                      
REMARK   3                 STEINER,NICHOLLS,WINN,LONG,VAGIN                     
REMARK   3                                                                      
REMARK   3    REFINEMENT TARGET : MAXIMUM LIKELIHOOD                            
REMARK   3                                                                      
REMARK   3  DATA USED IN REFINEMENT.                                            
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 1.85                           
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 42.7                           
REMARK   3   DATA CUTOFF            (SIGMA(F)) : NONE                           
REMARK   3   COMPLETENESS FOR RANGE        (%) : 97.7                           
REMARK   3   NUMBER OF REFLECTIONS             : 23299                          
REMARK   3                                                                      
REMARK   3  FIT TO DATA USED IN REFINEMENT.                                     
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT                      
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM                          
REMARK   3   R VALUE     (WORKING + TEST SET) : 0.191                           
REMARK   3   R VALUE            (WORKING SET) : 0.190                           
REMARK   3   FREE R VALUE                     : 0.213                           
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : 5.2                             
REMARK   3   FREE R VALUE TEST SET COUNT      : 1267                            
REMARK   3                                                                      
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.                                  
REMARK   3   TOTAL NUMBER OF BINS USED           : NULL                         
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : NULL                         
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : NULL                         
REMARK   3   REFLECTION IN BIN     (WORKING SET) : NULL                         
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : NULL                         
REMARK   3   BIN R VALUE           (WORKING SET) : NULL                         
REMARK   3   BIN FREE R VALUE SET COUNT          : NULL                         
REMARK   3   BIN FREE R VALUE                    : NULL                         
REMARK   3                                                                      
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.                    
REMARK   3   PROTEIN ATOMS            : 1881                                    
REMARK   3   NUCLEIC ACID ATOMS       : 0                                       
REMARK   3   HETEROGEN ATOMS          : 72                                      
REMARK   3   SOLVENT ATOMS            : 122                                     
REMARK   3                                                                      
REMARK   3  B VALUES.                                                           
REMARK   3   FROM WILSON PLOT           (A**2) : NULL                           
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : NULL                           
REMARK   3   OVERALL ANISOTROPIC B VALUE.                                       
REMARK   3    B11 (A**2) : NULL                                                 
REMARK   3    B22 (A**2) : NULL                                                 
REMARK   3    B33 (A**2) : NULL                                                 
REMARK   3    B12 (A**2) : NULL                                                 
REMARK   3    B13 (A**2) : NULL                                                 
REMARK   3    B23 (A**2) : NULL                                                 
REMARK   3                                                                      
REMARK   3  ESTIMATED OVERALL COORDINATE ERROR.                                 
REMARK   3   ESU BASED ON R VALUE                            (A): NULL          
REMARK   3   ESU BASED ON FREE R VALUE                       (A): NULL          
REMARK   3   ESU BASED ON MAXIMUM LIKELIHOOD                 (A): NULL          
REMARK   3   ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): NULL          
REMARK   3                                                                      
REMARK   3  CORRELATION COEFFICIENTS.                                           
REMARK   3   CORRELATION COEFFICIENT FO-FC      : NULL                          
REMARK   3   CORRELATION COEFFICIENT FO-FC FREE : NULL                          
REMARK   3                                                                      
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES        COUNT    RMS    WEIGHT      
REMARK   3   BOND LENGTHS REFINED ATOMS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   BOND LENGTHS OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   BOND ANGLES REFINED ATOMS   (DEGREES):  NULL ;  NULL ;  NULL       
REMARK   3   BOND ANGLES OTHERS          (DEGREES):  NULL ;  NULL ;  NULL       
REMARK   3   TORSION ANGLES, PERIOD 1    (DEGREES):  NULL ;  NULL ;  NULL       
REMARK   3   TORSION ANGLES, PERIOD 2    (DEGREES):  NULL ;  NULL ;  NULL       
REMARK   3   TORSION ANGLES, PERIOD 3    (DEGREES):  NULL ;  NULL ;  NULL       
REMARK   3   TORSION ANGLES, PERIOD 4    (DEGREES):  NULL ;  NULL ;  NULL       
REMARK   3   CHIRAL-CENTER RESTRAINTS       (A**3):  NULL ;  NULL ;  NULL       
REMARK   3   GENERAL PLANES REFINED ATOMS      (A):  NULL ;  NULL ;  NULL       
REMARK   3   GENERAL PLANES OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED CONTACTS OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   NON-BONDED TORSION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) REFINED ATOMS      (A):  NULL ;  NULL ;  NULL       
REMARK   3   H-BOND (X...Y) OTHERS             (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION REFINED ATOMS (A):  NULL ;  NULL ;  NULL       
REMARK   3   POTENTIAL METAL-ION OTHERS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW REFINED ATOMS        (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY VDW OTHERS               (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND REFINED ATOMS     (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY H-BOND OTHERS            (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION REFINED ATOMS  (A):  NULL ;  NULL ;  NULL       
REMARK   3   SYMMETRY METAL-ION OTHERS         (A):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.     COUNT   RMS    WEIGHT      
REMARK   3   MAIN-CHAIN BOND REFINED ATOMS  (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   MAIN-CHAIN BOND OTHER ATOMS    (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   MAIN-CHAIN ANGLE REFINED ATOMS (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN BOND REFINED ATOMS  (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SIDE-CHAIN ANGLE REFINED ATOMS (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  ANISOTROPIC THERMAL FACTOR RESTRAINTS.   COUNT   RMS    WEIGHT      
REMARK   3   RIGID-BOND RESTRAINTS          (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; FREE ATOMS         (A**2):  NULL ;  NULL ;  NULL       
REMARK   3   SPHERICITY; BONDED ATOMS       (A**2):  NULL ;  NULL ;  NULL       
REMARK   3                                                                      
REMARK   3  NCS RESTRAINTS STATISTICS                                           
REMARK   3   NUMBER OF DIFFERENT NCS GROUPS : NULL                              
REMARK   3                                                                      
REMARK   3  TLS DETAILS                                                         
REMARK   3   NUMBER OF TLS GROUPS  : NULL                                       
REMARK   3                                                                      
REMARK   3  BULK SOLVENT MODELLING.                                             
REMARK   3   METHOD USED : NULL                                                 
REMARK   3   PARAMETERS FOR MASK CALCULATION                                    
REMARK   3   VDW PROBE RADIUS   : NULL                                          
REMARK   3   ION PROBE RADIUS   : NULL                                          
REMARK   3   SHRINKAGE RADIUS   : NULL                                          
REMARK   3                                                                      
REMARK   3  OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE          
REMARK   3   RIDING POSITIONS.                                                  
REMARK   4                                                                      
REMARK   4 4CRB COMPLIES WITH FORMAT V. 3.30, 13-JUL-11                         
REMARK 100                                                                      
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 26-FEB-14.                  
REMARK 100 THE PDBE ID CODE IS EBI-59837.                                       
REMARK 200                                                                      
REMARK 200 EXPERIMENTAL DETAILS                                                 
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION                  
REMARK 200  DATE OF DATA COLLECTION        : 12-JUN-09                          
REMARK 200  TEMPERATURE           (KELVIN) : 100                                
REMARK 200  PH                             : 8.5                                
REMARK 200  NUMBER OF CRYSTALS USED        : 1                                  
REMARK 200                                                                      
REMARK 200  SYNCHROTRON              (Y/N) : Y                                  
REMARK 200  RADIATION SOURCE               : ESRF                               
REMARK 200  BEAMLINE                       : ID14-4                             
REMARK 200  X-RAY GENERATOR MODEL          : NULL                               
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M                                  
REMARK 200  WAVELENGTH OR RANGE        (A) : 0.94                               
REMARK 200  MONOCHROMATOR                  : NULL                               
REMARK 200  OPTICS                         : NULL                               
REMARK 200                                                                      
REMARK 200  DETECTOR TYPE                  : CCD                                
REMARK 200  DETECTOR MANUFACTURER          : ADSC                               
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : MOSFLM                             
REMARK 200  DATA SCALING SOFTWARE          : SCALA                              
REMARK 200                                                                      
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 25023                              
REMARK 200  RESOLUTION RANGE HIGH      (A) : 1.85                               
REMARK 200  RESOLUTION RANGE LOW       (A) : 50.00                              
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 2.0                                
REMARK 200                                                                      
REMARK 200 OVERALL.                                                             
REMARK 200  COMPLETENESS FOR RANGE     (%) : 99.5                               
REMARK 200  DATA REDUNDANCY                : 5.1                                
REMARK 200  R MERGE                    (I) : 0.08                               
REMARK 200  R SYM                      (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR THE DATA SET  : 13.90                              
REMARK 200                                                                      
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.                                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 1.85                     
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 1.90                     
REMARK 200  COMPLETENESS FOR SHELL     (%) : 100.0                              
REMARK 200  DATA REDUNDANCY IN SHELL       : 5.1                                
REMARK 200  R MERGE FOR SHELL          (I) : 0.63                               
REMARK 200  R SYM FOR SHELL            (I) : NULL                               
REMARK 200  <I/SIGMA(I)> FOR SHELL         : 2.20                               
REMARK 200                                                                      
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH                              
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT        
REMARK 200 SOFTWARE USED: MOLREP                                                
REMARK 200 STARTING MODEL: NONE                                                 
REMARK 200                                                                      
REMARK 200 REMARK: NONE                                                         
REMARK 280                                                                      
REMARK 280 CRYSTAL                                                              
REMARK 280 SOLVENT CONTENT, VS   (%): 55.41                                     
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.76                     
REMARK 280                                                                      
REMARK 280 CRYSTALLIZATION CONDITIONS: 2M AMMONIUM SULFATE 0.1M                 
REMARK 280  TRIS-CL PH 8.5 0.2M NACL                                            
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY                                            
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: I 2 3                            
REMARK 290                                                                      
REMARK 290      SYMOP   SYMMETRY                                                
REMARK 290     NNNMMM   OPERATOR                                                
REMARK 290       1555   X,Y,Z                                                   
REMARK 290       2555   -X,-Y,Z                                                 
REMARK 290       3555   -X,Y,-Z                                                 
REMARK 290       4555   X,-Y,-Z                                                 
REMARK 290       5555   Z,X,Y                                                   
REMARK 290       6555   Z,-X,-Y                                                 
REMARK 290       7555   -Z,-X,Y                                                 
REMARK 290       8555   -Z,X,-Y                                                 
REMARK 290       9555   Y,Z,X                                                   
REMARK 290      10555   -Y,Z,-X                                                 
REMARK 290      11555   Y,-Z,-X                                                 
REMARK 290      12555   -Y,-Z,X                                                 
REMARK 290      13555   X+1/2,Y+1/2,Z+1/2                                       
REMARK 290      14555   -X+1/2,-Y+1/2,Z+1/2                                     
REMARK 290      15555   -X+1/2,Y+1/2,-Z+1/2                                     
REMARK 290      16555   X+1/2,-Y+1/2,-Z+1/2                                     
REMARK 290      17555   Z+1/2,X+1/2,Y+1/2                                       
REMARK 290      18555   Z+1/2,-X+1/2,-Y+1/2                                     
REMARK 290      19555   -Z+1/2,-X+1/2,Y+1/2                                     
REMARK 290      20555   -Z+1/2,X+1/2,-Y+1/2                                     
REMARK 290      21555   Y+1/2,Z+1/2,X+1/2                                       
REMARK 290      22555   -Y+1/2,Z+1/2,-X+1/2                                     
REMARK 290      23555   Y+1/2,-Z+1/2,-X+1/2                                     
REMARK 290      24555   -Y+1/2,-Z+1/2,X+1/2                                     
REMARK 290                                                                      
REMARK 290     WHERE NNN -> OPERATOR NUMBER                                     
REMARK 290           MMM -> TRANSLATION VECTOR                                  
REMARK 290                                                                      
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS                            
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM             
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY                
REMARK 290 RELATED MOLECULES.                                                   
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   2  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   2  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY1   3 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   3  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   4  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY2   4  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY1   5  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY2   5  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   5  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   6  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY2   6 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   6  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   7  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY2   7 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   7  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   8  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY2   8  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY3   8  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY1   9  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY2   9  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY3   9  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  10  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY2  10  0.000000  0.000000  1.000000        0.00000            
REMARK 290   SMTRY3  10 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  11  0.000000  1.000000  0.000000        0.00000            
REMARK 290   SMTRY2  11  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY3  11 -1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  12  0.000000 -1.000000  0.000000        0.00000            
REMARK 290   SMTRY2  12  0.000000  0.000000 -1.000000        0.00000            
REMARK 290   SMTRY3  12  1.000000  0.000000  0.000000        0.00000            
REMARK 290   SMTRY1  13  1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY2  13  0.000000  1.000000  0.000000       60.49500            
REMARK 290   SMTRY3  13  0.000000  0.000000  1.000000       60.49500            
REMARK 290   SMTRY1  14 -1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY2  14  0.000000 -1.000000  0.000000       60.49500            
REMARK 290   SMTRY3  14  0.000000  0.000000  1.000000       60.49500            
REMARK 290   SMTRY1  15 -1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY2  15  0.000000  1.000000  0.000000       60.49500            
REMARK 290   SMTRY3  15  0.000000  0.000000 -1.000000       60.49500            
REMARK 290   SMTRY1  16  1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY2  16  0.000000 -1.000000  0.000000       60.49500            
REMARK 290   SMTRY3  16  0.000000  0.000000 -1.000000       60.49500            
REMARK 290   SMTRY1  17  0.000000  0.000000  1.000000       60.49500            
REMARK 290   SMTRY2  17  1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY3  17  0.000000  1.000000  0.000000       60.49500            
REMARK 290   SMTRY1  18  0.000000  0.000000  1.000000       60.49500            
REMARK 290   SMTRY2  18 -1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY3  18  0.000000 -1.000000  0.000000       60.49500            
REMARK 290   SMTRY1  19  0.000000  0.000000 -1.000000       60.49500            
REMARK 290   SMTRY2  19 -1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY3  19  0.000000  1.000000  0.000000       60.49500            
REMARK 290   SMTRY1  20  0.000000  0.000000 -1.000000       60.49500            
REMARK 290   SMTRY2  20  1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY3  20  0.000000 -1.000000  0.000000       60.49500            
REMARK 290   SMTRY1  21  0.000000  1.000000  0.000000       60.49500            
REMARK 290   SMTRY2  21  0.000000  0.000000  1.000000       60.49500            
REMARK 290   SMTRY3  21  1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY1  22  0.000000 -1.000000  0.000000       60.49500            
REMARK 290   SMTRY2  22  0.000000  0.000000  1.000000       60.49500            
REMARK 290   SMTRY3  22 -1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY1  23  0.000000  1.000000  0.000000       60.49500            
REMARK 290   SMTRY2  23  0.000000  0.000000 -1.000000       60.49500            
REMARK 290   SMTRY3  23 -1.000000  0.000000  0.000000       60.49500            
REMARK 290   SMTRY1  24  0.000000 -1.000000  0.000000       60.49500            
REMARK 290   SMTRY2  24  0.000000  0.000000 -1.000000       60.49500            
REMARK 290   SMTRY3  24  1.000000  0.000000  0.000000       60.49500            
REMARK 290                                                                      
REMARK 290 REMARK: NULL                                                         
REMARK 300                                                                      
REMARK 300 BIOMOLECULE: 1                                                       
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM                
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN                  
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON               
REMARK 300 BURIED SURFACE AREA.                                                 
REMARK 350                                                                      
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN           
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE                
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS          
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND                          
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.                               
REMARK 350                                                                      
REMARK 350 BIOMOLECULE: 1                                                       
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC                         
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: MONOMERIC                  
REMARK 350 SOFTWARE USED: PISA                                                  
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A                                     
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000            
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000            
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000            
REMARK 375                                                                      
REMARK 375 SPECIAL POSITION                                                     
REMARK 375 THE FOLLOWING ATOMS ARE FOUND TO BE WITHIN 0.15 ANGSTROMS            
REMARK 375 OF A SYMMETRY RELATED ATOM AND ARE ASSUMED TO BE ON SPECIAL          
REMARK 375 POSITIONS.                                                           
REMARK 375                                                                      
REMARK 375 ATOM RES CSSEQI                                                      
REMARK 375 O4   SO4 A1488   LIES ON A SPECIAL POSITION.                         
REMARK 375 S    SO4 A1488   LIES ON A SPECIAL POSITION.                         
REMARK 375      HOH A2122   LIES ON A SPECIAL POSITION.                         
REMARK 500                                                                      
REMARK 500 GEOMETRY AND STEREOCHEMISTRY                                         
REMARK 500 SUBTOPIC: TORSION ANGLES                                             
REMARK 500                                                                      
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:            
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).                             
REMARK 500                                                                      
REMARK 500 STANDARD TABLE:                                                      
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)                    
REMARK 500                                                                      
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-           
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400            
REMARK 500                                                                      
REMARK 500  M RES CSSEQI        PSI       PHI                                   
REMARK 500    ASP A 148     -143.83   -160.47                                   
REMARK 500    SER A 214      -63.55   -122.84                                   
REMARK 500                                                                      
REMARK 500 REMARK: NULL                                                         
REMARK 525                                                                      
REMARK 525 SOLVENT                                                              
REMARK 525                                                                      
REMARK 525 THE FOLLOWING SOLVENT MOLECULES LIE FARTHER THAN EXPECTED            
REMARK 525 FROM THE PROTEIN OR NUCLEIC ACID MOLECULE AND ARE                    
REMARK 525 ASSOCIATED WITH A SYMMETRY RELATED MOLECULE (M=MODEL                 
REMARK 525 NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE          
REMARK 525 NUMBER; I=INSERTION CODE): THESE HAVE BEEN REPOSITIONED              
REMARK 525 BY APPLYING THE SYMMETRY TRANSFORMATION INDICATED.                   
REMARK 525                                                                      
REMARK 525  M RES CSSEQI     ORIGINAL COORDINATES   SYMMETRY TRANS.    DIST.    
REMARK 525                    X       Y       Z                                 
REMARK 525    HOH W  62    33.827  -5.410  55.410    004      556      3.15     
REMARK 525    HOH W 126    34.972  18.094  29.236    009      555      3.14     
REMARK 525    HOH W 128    49.623   1.754  28.953    019      555      3.66     
REMARK 630                                                                      
REMARK 630 MOLECULE TYPE: NULL                                                  
REMARK 630 MOLECULE NAME: N-[(1S)-1-BENZYL-2-[2-[5-CHLORO-2-(TETRAZOL-          
REMARK 630  1-YL)PHENYL]ETHYLAMINO]-2-OXO-ETHYL]-4-HYDROXY-2-OXO-               
REMARK 630  1H-QUINOLINE-6-CARBOXAMIDE                                          
REMARK 630                                                                      
REMARK 630 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;               
REMARK 630  SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)                           
REMARK 630                                                                      
REMARK 630   M RES C SSSEQI                                                     
REMARK 630     7P0 A  1485                                                      
REMARK 630 SOURCE: NULL                                                         
REMARK 630 TAXONOMY: NULL                                                       
REMARK 630 SUBCOMP:    7DM PHE BXR                                              
REMARK 630 DETAILS: NULL                                                        
REMARK 700                                                                      
REMARK 700 SHEET                                                                
REMARK 700 DETERMINATION METHOD: DSSP                                           
REMARK 700 THE SHEETS PRESENTED AS "AB" IN EACH CHAIN ON SHEET RECORDS          
REMARK 700 BELOW IS ACTUALLY AN  6-STRANDED BARREL THIS IS REPRESENTED BY       
REMARK 700 A  7-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS              
REMARK 700 ARE IDENTICAL.                                                       
REMARK 800                                                                      
REMARK 800 SITE                                                                 
REMARK 800 SITE_IDENTIFIER: AC1                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE GOL A1483                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC2                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE GOL A1484                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC3                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE 7P0 A1485                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC4                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A1486                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC5                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A1487                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC6                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A1488                 
REMARK 800                                                                      
REMARK 800 SITE_IDENTIFIER: AC7                                                 
REMARK 800 EVIDENCE_CODE: SOFTWARE                                              
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE SO4 A1489                 
REMARK 900                                                                      
REMARK 900 RELATED ENTRIES                                                      
REMARK 900 RELATED ID: 4CR5   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CR9   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRA   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRC   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRD   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRE   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRF   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
REMARK 900 RELATED ID: 4CRG   RELATED DB: PDB                                   
REMARK 900  CREATING NOVEL F1 INHIBITORS THROUGH FRAGMENT BASED LEAD            
REMARK 900   GENERATION AND STRUCTURE AIDED DRUG DESIGN                         
DBREF  4CRB A   16   245  UNP    P03951   FA11_HUMAN     388    625             
SEQADV 4CRB ALA A   75  UNP  P03951    SER   452 ENGINEERED MUTATION            
SEQADV 4CRB ALA A   78  UNP  P03951    LYS   455 ENGINEERED MUTATION            
SEQADV 4CRB ALA A  115  UNP  P03951    THR   493 ENGINEERED MUTATION            
SEQADV 4CRB SER A  123  UNP  P03951    CYS   500 ENGINEERED MUTATION            
SEQRES   1 A  238  ILE VAL GLY GLY THR ALA SER VAL ARG GLY GLU TRP PRO          
SEQRES   2 A  238  TRP GLN VAL THR LEU HIS THR THR SER PRO THR GLN ARG          
SEQRES   3 A  238  HIS LEU CYS GLY GLY SER ILE ILE GLY ASN GLN TRP ILE          
SEQRES   4 A  238  LEU THR ALA ALA HIS CYS PHE TYR GLY VAL GLU SER PRO          
SEQRES   5 A  238  LYS ILE LEU ARG VAL TYR SER GLY ILE LEU ASN GLN ALA          
SEQRES   6 A  238  GLU ILE ALA GLU ASP THR SER PHE PHE GLY VAL GLN GLU          
SEQRES   7 A  238  ILE ILE ILE HIS ASP GLN TYR LYS MET ALA GLU SER GLY          
SEQRES   8 A  238  TYR ASP ILE ALA LEU LEU LYS LEU GLU THR THR VAL ASN          
SEQRES   9 A  238  TYR ALA ASP SER GLN ARG PRO ILE SER LEU PRO SER LYS          
SEQRES  10 A  238  GLY ASP ARG ASN VAL ILE TYR THR ASP CYS TRP VAL THR          
SEQRES  11 A  238  GLY TRP GLY TYR ARG LYS LEU ARG ASP LYS ILE GLN ASN          
SEQRES  12 A  238  THR LEU GLN LYS ALA LYS ILE PRO LEU VAL THR ASN GLU          
SEQRES  13 A  238  GLU CYS GLN LYS ARG TYR ARG GLY HIS LYS ILE THR HIS          
SEQRES  14 A  238  LYS MET ILE CYS ALA GLY TYR ARG GLU GLY GLY LYS ASP          
SEQRES  15 A  238  ALA CYS LYS GLY ASP SER GLY GLY PRO LEU SER CYS LYS          
SEQRES  16 A  238  HIS ASN GLU VAL TRP HIS LEU VAL GLY ILE THR SER TRP          
SEQRES  17 A  238  GLY GLU GLY CYS ALA GLN ARG GLU ARG PRO GLY VAL TYR          
SEQRES  18 A  238  THR ASN VAL VAL GLU TYR VAL ASP TRP ILE LEU GLU LYS          
SEQRES  19 A  238  THR GLN ALA VAL                                              
HET    GOL  A1483       6                                                       
HET    GOL  A1484       6                                                       
HET    7P0  A1485      40                                                       
HET    SO4  A1486       5                                                       
HET    SO4  A1487       5                                                       
HET    SO4  A1488       5                                                       
HET    SO4  A1489       5                                                       
HETNAM     7P0 N-[(1S)-1-BENZYL-2-[2-[5-CHLORO-2-(TETRAZOL-                     
HETNAM   2 7P0  1-YL)PHENYL]ETHYLAMINO]-2-OXO-ETHYL]-4-                         
HETNAM   3 7P0  HYDROXY-2-OXO-1H-QUINOLINE-6-CARBOXAMIDE                        
HETNAM     SO4 SULFATE ION                                                      
HETNAM     GOL GLYCEROL                                                         
HETSYN     GOL GLYCERIN                                                         
FORMUL   2  7P0    C28 H24 CL N7 O4                                             
FORMUL   3  SO4    4(O4 S 2-)                                                   
FORMUL   4  GOL    2(C3 H8 O3)                                                  
FORMUL   5  HOH   *122(H2 O)                                                    
HELIX    1   1 ALA A   55  TYR A   59A 5                                   6    
HELIX    2   2 SER A   61  LYS A   63  5                                   3    
HELIX    3   3 GLN A   74  ILE A   77  5                                   4    
HELIX    4   4 MET A   96  GLY A  100  5                                   5    
HELIX    5   5 SER A  126  ARG A  130  5                                   5    
HELIX    6   6 THR A  164  TYR A  172  1                                   9    
HELIX    7   7 TYR A  234  THR A  242  1                                   9    
SHEET    1  AA 8 THR A  20  ALA A  21  0                                        
SHEET    2  AA 8 GLN A 156  LYS A 159 -1  O  LYS A 157   N  THR A  20           
SHEET    3  AA 8 CYS A 136  GLY A 140 -1  O  VAL A 138   N  ALA A 158           
SHEET    4  AA 8 PRO A 198  HIS A 202A-1  O  PRO A 198   N  THR A 139           
SHEET    5  AA 8 VAL A 202D TRP A 215 -1  O  VAL A 202D  N  HIS A 202A          
SHEET    6  AA 8 GLY A 226  ASN A 230 -1  O  VAL A 227   N  TRP A 215           
SHEET    7  AA 8 MET A 180  ALA A 183 -1  O  ILE A 181   N  TYR A 228           
SHEET    8  AA 8 LEU A 162  VAL A 163 -1  O  VAL A 163   N  CYS A 182           
SHEET    1  AB 7 GLN A  30  THR A  35  0                                        
SHEET    2  AB 7 ARG A  37D GLY A  46 -1  O  ARG A  37D  N  THR A  35           
SHEET    3  AB 7 TRP A  51  THR A  54 -1  O  TRP A  51   N  ILE A  45           
SHEET    4  AB 7 ALA A 104  LEU A 108 -1  O  ALA A 104   N  THR A  54           
SHEET    5  AB 7 PHE A  83  ILE A  90 -1  N  GLN A  86   O  LYS A 107           
SHEET    6  AB 7 LEU A  65  TYR A  68 -1  O  LEU A  65   N  VAL A  85           
SHEET    7  AB 7 GLN A  30  THR A  35 -1  O  THR A  32   N  TYR A  68           
SSBOND   1 CYS A   40    CYS A   58                          1555   1555  2.02  
SSBOND   2 CYS A  136    CYS A  201                          1555   1555  2.05  
SSBOND   3 CYS A  168    CYS A  182                          1555   1555  2.03  
SSBOND   4 CYS A  191    CYS A  219                          1555   1555  2.02  
CISPEP   1 SER A   37    PRO A   37A         0        -0.27                     
SITE     1 AC1  3 ARG A  37D 7P0 A1485  HOH A2119                               
SITE     1 AC2  7 HIS A  57  SER A 214  TRP A 215  7P0 A1485                    
SITE     2 AC2  7 HOH A2035  HOH A2104  HOH A2108                               
SITE     1 AC3 25 HIS A  38  LEU A  39  HIS A  57  TYR A 143                    
SITE     2 AC3 25 ILE A 151  ASP A 189  ALA A 190  CYS A 191                    
SITE     3 AC3 25 LYS A 192  GLY A 193  ASP A 194  SER A 195                    
SITE     4 AC3 25 THR A 213  TRP A 215  GLY A 216  GLY A 218                    
SITE     5 AC3 25 CYS A 219  GLY A 226  VAL A 227  GOL A1483                    
SITE     6 AC3 25 GOL A1484  HOH A2025  HOH A2027  HOH A2104                    
SITE     7 AC3 25 HOH A2121                                                     
SITE     1 AC4  5 THR A  20  ALA A  21  GLN A  48  GLN A  86                    
SITE     2 AC4  5 ARG A 144                                                     
SITE     1 AC5  3 LYS A 202  TRP A 203  HOH A2010                               
SITE     1 AC6  3 LYS A 127  ARG A 130  HOH A2122                               
SITE     1 AC7  3 TYR A 184A ARG A 185  GLU A 186                               
CRYST1  120.990  120.990  120.990  90.00  90.00  90.00 I 2 3        24          
ORIGX1      1.000000  0.000000  0.000000        0.00000                         
ORIGX2      0.000000  1.000000  0.000000        0.00000                         
ORIGX3      0.000000  0.000000  1.000000        0.00000                         
SCALE1      0.008265  0.000000  0.000000        0.00000                         
SCALE2      0.000000  0.008265  0.000000        0.00000                         
SCALE3      0.000000  0.000000  0.008265        0.00000                         
ATOM      1  N   ILE A  16      21.604   2.792  48.312  1.00 20.66           N  
ATOM      2  CA  ILE A  16      20.597   2.736  47.220  1.00 21.39           C  
ATOM      3  C   ILE A  16      19.339   2.030  47.729  1.00 22.12           C  
ATOM      4  O   ILE A  16      19.401   0.904  48.195  1.00 21.90           O  
ATOM      5  CB  ILE A  16      21.108   1.992  45.959  1.00 21.15           C  
ATOM      6  CG1 ILE A  16      22.405   2.622  45.405  1.00 20.73           C  
ATOM      7  CG2 ILE A  16      20.020   1.954  44.889  1.00 20.74           C  
ATOM      8  CD1 ILE A  16      22.251   3.958  44.706  1.00 21.33           C  
ATOM      9  N   VAL A  17      18.202   2.700  47.611  1.00 24.96           N  
ATOM     10  CA  VAL A  17      16.915   2.113  48.000  1.00 26.07           C  
ATOM     11  C   VAL A  17      16.291   1.512  46.744  1.00 26.69           C  
ATOM     12  O   VAL A  17      16.295   2.146  45.693  1.00 27.21           O  
ATOM     13  CB  VAL A  17      15.947   3.176  48.548  1.00 27.72           C  
ATOM     14  CG1 VAL A  17      14.595   2.546  48.896  1.00 27.35           C  
ATOM     15  CG2 VAL A  17      16.556   3.887  49.751  1.00 27.98           C  
ATOM     16  N   GLY A  18      15.762   0.297  46.863  1.00 26.75           N  
ATOM     17  CA  GLY A  18      15.008  -0.333  45.773  1.00 28.14           C  
ATOM     18  C   GLY A  18      15.823  -0.781  44.571  1.00 27.99           C  
ATOM     19  O   GLY A  18      15.291  -0.921  43.468  1.00 28.00           O  
ATOM     20  N   GLY A  19      17.110  -1.007  44.778  1.00 28.80           N  
ATOM     21  CA  GLY A  19      18.009  -1.396  43.687  1.00 29.05           C  
ATOM     22  C   GLY A  19      18.343  -2.869  43.774  1.00 28.63           C  
ATOM     23  O   GLY A  19      17.725  -3.602  44.539  1.00 28.85           O  
ATOM     24  N   THR A  20      19.325  -3.303  42.993  1.00 28.90           N  
ATOM     25  CA  THR A  20      19.786  -4.690  43.035  1.00 27.87           C  
ATOM     26  C   THR A  20      21.307  -4.702  43.023  1.00 27.61           C  
ATOM     27  O   THR A  20      21.940  -3.680  42.729  1.00 28.11           O  
ATOM     28  CB  THR A  20      19.269  -5.493  41.827  1.00 29.91           C  
ATOM     29  OG1 THR A  20      19.669  -4.844  40.613  1.00 29.38           O  
ATOM     30  CG2 THR A  20      17.746  -5.607  41.850  1.00 31.54           C  
ATOM     31  N   ALA A  21      21.891  -5.850  43.347  1.00 25.61           N  
ATOM     32  CA  ALA A  21      23.342  -6.022  43.288  1.00 25.77           C  
ATOM     33  C   ALA A  21      23.879  -5.791  41.878  1.00 24.39           C  
ATOM     34  O   ALA A  21      23.267  -6.183  40.872  1.00 22.14           O  
ATOM     35  CB  ALA A  21      23.749  -7.396  43.787  1.00 25.24           C  
ATOM     36  N   SER A  22      25.030  -5.139  41.816  1.00 24.30           N  
ATOM     37  CA  SER A  22      25.707  -4.909  40.551  1.00 24.02           C  
ATOM     38  C   SER A  22      26.483  -6.146  40.179  1.00 24.79           C  
ATOM     39  O   SER A  22      26.843  -6.933  41.039  1.00 24.82           O  
ATOM     40  CB  SER A  22      26.656  -3.719  40.672  1.00 23.85           C  
ATOM     41  OG  SER A  22      25.910  -2.526  40.846  1.00 23.30           O  
ATOM     42  N   VAL A  23      26.728  -6.308  38.886  1.00 26.54           N  
ATOM     43  CA  VAL A  23      27.719  -7.260  38.397  1.00 27.69           C  
ATOM     44  C   VAL A  23      29.109  -6.670  38.559  1.00 26.16           C  
ATOM     45  O   VAL A  23      29.319  -5.474  38.341  1.00 25.64           O  
ATOM     46  CB  VAL A  23      27.439  -7.630  36.925  1.00 29.93           C  
ATOM     47  CG1 VAL A  23      28.620  -8.337  36.279  1.00 30.68           C  
ATOM     48  CG2 VAL A  23      26.212  -8.530  36.869  1.00 32.31           C  
ATOM     49  N   ARG A  24      30.066  -7.506  38.933  1.00 25.37           N  
ATOM     50  CA  ARG A  24      31.452  -7.063  39.050  1.00 27.03           C  
ATOM     51  C   ARG A  24      31.952  -6.356  37.777  1.00 27.89           C  
ATOM     52  O   ARG A  24      31.838  -6.875  36.666  1.00 25.28           O  
ATOM     53  CB  ARG A  24      32.370  -8.233  39.396  1.00 27.94           C  
ATOM     54  CG  ARG A  24      33.747  -7.804  39.880  1.00 28.41           C  
ATOM     55  CD  ARG A  24      34.592  -9.001  40.295  1.00 29.55           C  
ATOM     56  NE  ARG A  24      34.254  -9.468  41.636  1.00 29.42           N  
ATOM     57  CZ  ARG A  24      34.675  -8.892  42.764  1.00 31.25           C  
ATOM     58  NH1 ARG A  24      35.461  -7.809  42.731  1.00 32.31           N  
ATOM     59  NH2 ARG A  24      34.300  -9.390  43.926  1.00 31.04           N  
ATOM     60  N   GLY A  25      32.481  -5.147  37.950  1.00 27.98           N  
ATOM     61  CA  GLY A  25      33.057  -4.399  36.845  1.00 27.77           C  
ATOM     62  C   GLY A  25      32.060  -3.748  35.906  1.00 27.02           C  
ATOM     63  O   GLY A  25      32.449  -3.201  34.888  1.00 26.70           O  
ATOM     64  N   GLU A  26      30.781  -3.760  36.232  1.00 25.30           N  
ATOM     65  CA  GLU A  26      29.829  -3.122  35.328  1.00 25.13           C  
ATOM     66  C   GLU A  26      29.764  -1.603  35.498  1.00 23.45           C  
ATOM     67  O   GLU A  26      29.268  -0.918  34.618  1.00 23.77           O  
ATOM     68  CB  GLU A  26      28.462  -3.775  35.437  1.00 26.71           C  
ATOM     69  CG  GLU A  26      27.565  -3.329  36.559  1.00 27.83           C  
ATOM     70  CD  GLU A  26      26.148  -3.818  36.352  1.00 28.14           C  
ATOM     71  OE1 GLU A  26      25.571  -3.509  35.294  1.00 31.68           O  
ATOM     72  OE2 GLU A  26      25.609  -4.509  37.232  1.00 27.26           O  
ATOM     73  N   TRP A  27      30.287  -1.082  36.610  1.00 21.90           N  
ATOM     74  CA  TRP A  27      30.408   0.360  36.826  1.00 22.28           C  
ATOM     75  C   TRP A  27      31.872   0.666  37.187  1.00 22.40           C  
ATOM     76  O   TRP A  27      32.189   1.002  38.334  1.00 21.18           O  
ATOM     77  CB  TRP A  27      29.477   0.814  37.948  1.00 21.80           C  
ATOM     78  CG  TRP A  27      28.112   0.293  37.816  1.00 21.26           C  
ATOM     79  CD1 TRP A  27      27.536  -0.675  38.582  1.00 21.64           C  
ATOM     80  CD2 TRP A  27      27.117   0.720  36.894  1.00 21.28           C  
ATOM     81  NE1 TRP A  27      26.244  -0.878  38.190  1.00 21.39           N  
ATOM     82  CE2 TRP A  27      25.962  -0.041  37.148  1.00 21.84           C  
ATOM     83  CE3 TRP A  27      27.086   1.670  35.867  1.00 21.13           C  
ATOM     84  CZ2 TRP A  27      24.794   0.106  36.412  1.00 21.56           C  
ATOM     85  CZ3 TRP A  27      25.918   1.816  35.141  1.00 21.26           C  
ATOM     86  CH2 TRP A  27      24.790   1.039  35.420  1.00 21.48           C  
ATOM     87  N   PRO A  28      32.774   0.512  36.207  1.00 21.18           N  
ATOM     88  CA  PRO A  28      34.206   0.539  36.477  1.00 21.00           C  
ATOM     89  C   PRO A  28      34.764   1.926  36.813  1.00 20.10           C  
ATOM     90  O   PRO A  28      35.907   2.031  37.220  1.00 20.30           O  
ATOM     91  CB  PRO A  28      34.811   0.002  35.173  1.00 21.68           C  
ATOM     92  CG  PRO A  28      33.810   0.398  34.124  1.00 22.06           C  
ATOM     93  CD  PRO A  28      32.487   0.188  34.799  1.00 22.07           C  
ATOM     94  N   TRP A  29      33.962   2.974  36.649  1.00 19.94           N  
ATOM     95  CA  TRP A  29      34.350   4.325  37.069  1.00 20.39           C  
ATOM     96  C   TRP A  29      34.027   4.566  38.558  1.00 20.44           C  
ATOM     97  O   TRP A  29      34.531   5.512  39.157  1.00 20.67           O  
ATOM     98  CB  TRP A  29      33.670   5.381  36.178  1.00 20.32           C  
ATOM     99  CG  TRP A  29      32.203   5.157  35.961  1.00 20.98           C  
ATOM    100  CD1 TRP A  29      31.184   5.651  36.711  1.00 21.92           C  
ATOM    101  CD2 TRP A  29      31.597   4.375  34.924  1.00 22.84           C  
ATOM    102  NE1 TRP A  29      29.972   5.236  36.202  1.00 23.40           N  
ATOM    103  CE2 TRP A  29      30.198   4.444  35.110  1.00 23.08           C  
ATOM    104  CE3 TRP A  29      32.102   3.617  33.857  1.00 23.36           C  
ATOM    105  CZ2 TRP A  29      29.294   3.792  34.264  1.00 24.32           C  
ATOM    106  CZ3 TRP A  29      31.199   2.965  33.012  1.00 24.11           C  
ATOM    107  CH2 TRP A  29      29.811   3.058  33.226  1.00 24.29           C  
ATOM    108  N   GLN A  30      33.195   3.707  39.136  1.00 19.15           N  
ATOM    109  CA  GLN A  30      32.742   3.875  40.529  1.00 19.19           C  
ATOM    110  C   GLN A  30      33.855   3.536  41.510  1.00 18.72           C  
ATOM    111  O   GLN A  30      34.421   2.450  41.470  1.00 18.07           O  
ATOM    112  CB  GLN A  30      31.535   2.967  40.816  1.00 19.21           C  
ATOM    113  CG  GLN A  30      31.094   2.907  42.281  1.00 18.97           C  
ATOM    114  CD  GLN A  30      30.082   3.977  42.654  1.00 19.69           C  
ATOM    115  OE1 GLN A  30      28.981   4.032  42.100  1.00 19.22           O  
ATOM    116  NE2 GLN A  30      30.441   4.823  43.616  1.00 18.63           N  
ATOM    117  N   VAL A  31      34.149   4.470  42.403  1.00 18.75           N  
ATOM    118  CA  VAL A  31      35.068   4.212  43.481  1.00 18.57           C  
ATOM    119  C   VAL A  31      34.359   4.372  44.815  1.00 18.77           C  
ATOM    120  O   VAL A  31      33.294   4.977  44.906  1.00 17.08           O  
ATOM    121  CB  VAL A  31      36.313   5.117  43.429  1.00 18.94           C  
ATOM    122  CG1 VAL A  31      37.018   4.939  42.086  1.00 19.99           C  
ATOM    123  CG2 VAL A  31      35.973   6.579  43.684  1.00 18.80           C  
ATOM    124  N   THR A  32      34.957   3.751  45.818  1.00 19.52           N  
ATOM    125  CA  THR A  32      34.599   3.958  47.211  1.00 19.20           C  
ATOM    126  C   THR A  32      35.729   4.729  47.874  1.00 18.46           C  
ATOM    127  O   THR A  32      36.895   4.324  47.837  1.00 18.42           O  
ATOM    128  CB  THR A  32      34.283   2.634  47.956  1.00 19.52           C  
ATOM    129  OG1 THR A  32      34.148   2.887  49.354  1.00 20.55           O  
ATOM    130  CG2 THR A  32      35.329   1.566  47.733  1.00 20.04           C  
ATOM    131  N   LEU A  33      35.371   5.881  48.428  1.00 18.56           N  
ATOM    132  CA  LEU A  33      36.303   6.750  49.122  1.00 18.71           C  
ATOM    133  C   LEU A  33      36.158   6.426  50.593  1.00 19.71           C  
ATOM    134  O   LEU A  33      35.055   6.490  51.141  1.00 19.02           O  
ATOM    135  CB  LEU A  33      35.952   8.209  48.859  1.00 19.50           C  
ATOM    136  CG  LEU A  33      36.750   9.290  49.590  1.00 21.02           C  
ATOM    137  CD1 LEU A  33      38.201   9.368  49.125  1.00 21.35           C  
ATOM    138  CD2 LEU A  33      36.059  10.634  49.415  1.00 22.02           C  
ATOM    139  N   HIS A  34      37.273   6.047  51.205  1.00 19.64           N  
ATOM    140  CA  HIS A  34      37.342   5.769  52.621  1.00 19.90           C  
ATOM    141  C   HIS A  34      38.060   6.860  53.366  1.00 19.89           C  
ATOM    142  O   HIS A  34      38.907   7.558  52.809  1.00 20.24           O  
ATOM    143  CB  HIS A  34      38.113   4.484  52.866  1.00 19.10           C  
ATOM    144  CG  HIS A  34      37.307   3.262  52.657  1.00 19.15           C  
ATOM    145  ND1 HIS A  34      37.474   2.137  53.427  1.00 19.39           N  
ATOM    146  CD2 HIS A  34      36.310   2.980  51.786  1.00 19.21           C  
ATOM    147  CE1 HIS A  34      36.637   1.202  53.026  1.00 19.49           C  
ATOM    148  NE2 HIS A  34      35.916   1.687  52.032  1.00 19.94           N  
ATOM    149  N   THR A  35      37.722   6.964  54.646  1.00 20.14           N  
ATOM    150  CA  THR A  35      38.517   7.712  55.615  1.00 20.80           C  
ATOM    151  C   THR A  35      39.079   6.714  56.621  1.00 21.01           C  
ATOM    152  O   THR A  35      38.420   5.734  56.949  1.00 22.03           O  
ATOM    153  CB  THR A  35      37.688   8.785  56.351  1.00 21.40           C  
ATOM    154  OG1 THR A  35      38.487   9.395  57.376  1.00 22.63           O  
ATOM    155  CG2 THR A  35      36.441   8.201  56.970  1.00 21.36           C  
ATOM    156  N   THR A  36      40.294   6.960  57.099  1.00 23.02           N  
ATOM    157  CA  THR A  36      40.936   6.089  58.086  1.00 24.71           C  
ATOM    158  C   THR A  36      40.680   6.571  59.519  1.00 26.55           C  
ATOM    159  O   THR A  36      41.111   5.928  60.484  1.00 25.35           O  
ATOM    160  CB  THR A  36      42.451   6.044  57.860  1.00 24.85           C  
ATOM    161  OG1 THR A  36      42.973   7.375  57.945  1.00 25.26           O  
ATOM    162  CG2 THR A  36      42.775   5.462  56.480  1.00 25.02           C  
ATOM    163  N   SER A  37      39.971   7.687  59.653  1.00 26.88           N  
ATOM    164  CA  SER A  37      39.781   8.329  60.946  1.00 29.04           C  
ATOM    165  C   SER A  37      38.328   8.303  61.453  1.00 28.45           C  
ATOM    166  O   SER A  37      37.419   8.720  60.732  1.00 29.13           O  
ATOM    167  CB  SER A  37      40.260   9.773  60.851  1.00 30.26           C  
ATOM    168  OG  SER A  37      39.844  10.490  61.987  1.00 34.63           O  
ATOM    169  N   PRO A  37A     38.102   7.851  62.709  1.00 26.04           N  
ATOM    170  CA  PRO A  37A     39.083   7.358  63.693  1.00 26.05           C  
ATOM    171  C   PRO A  37A     39.547   5.939  63.375  1.00 25.41           C  
ATOM    172  O   PRO A  37A     40.698   5.603  63.613  1.00 25.95           O  
ATOM    173  CB  PRO A  37A     38.306   7.399  65.018  1.00 25.80           C  
ATOM    174  CG  PRO A  37A     36.887   7.233  64.626  1.00 25.19           C  
ATOM    175  CD  PRO A  37A     36.745   7.913  63.281  1.00 25.87           C  
ATOM    176  N   THR A  37B     38.645   5.121  62.837  1.00 25.08           N  
ATOM    177  CA  THR A  37B     39.015   3.857  62.213  1.00 25.76           C  
ATOM    178  C   THR A  37B     38.401   3.817  60.820  1.00 26.06           C  
ATOM    179  O   THR A  37B     37.448   4.566  60.507  1.00 25.55           O  
ATOM    180  CB  THR A  37B     38.510   2.629  62.995  1.00 26.39           C  
ATOM    181  OG1 THR A  37B     37.084   2.697  63.142  1.00 25.61           O  
ATOM    182  CG2 THR A  37B     39.174   2.565  64.371  1.00 26.92           C  
ATOM    183  N   GLN A  37C     38.930   2.929  59.992  1.00 24.75           N  
ATOM    184  CA  GLN A  37C     38.650   2.988  58.559  1.00 24.50           C  
ATOM    185  C   GLN A  37C     37.215   2.632  58.198  1.00 23.52           C  
ATOM    186  O   GLN A  37C     36.654   1.648  58.684  1.00 23.03           O  
ATOM    187  CB  GLN A  37C     39.638   2.133  57.765  1.00 24.18           C  
ATOM    188  CG  GLN A  37C     39.508   2.361  56.264  1.00 24.04           C  
ATOM    189  CD  GLN A  37C     40.561   1.619  55.460  1.00 23.60           C  
ATOM    190  OE1 GLN A  37C     41.724   1.560  55.838  1.00 23.60           O  
ATOM    191  NE2 GLN A  37C     40.156   1.062  54.328  1.00 25.06           N  
ATOM    192  N   ARG A  37D     36.624   3.453  57.334  1.00 23.29           N  
ATOM    193  CA  ARG A  37D     35.237   3.301  56.939  1.00 23.74           C  
ATOM    194  C   ARG A  37D     34.974   4.004  55.611  1.00 21.73           C  
ATOM    195  O   ARG A  37D     35.650   4.964  55.254  1.00 19.20           O  
ATOM    196  CB  ARG A  37D     34.308   3.893  58.012  1.00 27.76           C  
ATOM    197  CG  ARG A  37D     34.591   5.352  58.369  1.00 30.93           C  
ATOM    198  CD  ARG A  37D     34.029   5.742  59.736  1.00 34.69           C  
ATOM    199  NE  ARG A  37D     34.764   5.130  60.851  1.00 37.09           N  
ATOM    200  CZ  ARG A  37D     34.448   5.260  62.142  1.00 38.55           C  
ATOM    201  NH1 ARG A  37D     33.399   5.990  62.517  1.00 40.49           N  
ATOM    202  NH2 ARG A  37D     35.187   4.658  63.066  1.00 37.72           N  
ATOM    203  N   HIS A  38      33.964   3.516  54.898  1.00 20.95           N  
ATOM    204  CA  HIS A  38      33.486   4.156  53.676  1.00 20.00           C  
ATOM    205  C   HIS A  38      32.908   5.531  53.981  1.00 20.42           C  
ATOM    206  O   HIS A  38      32.116   5.684  54.924  1.00 20.87           O  
ATOM    207  CB  HIS A  38      32.424   3.275  53.014  1.00 19.99           C  
ATOM    208  CG  HIS A  38      31.623   3.962  51.951  1.00 19.67           C  
ATOM    209  ND1 HIS A  38      32.014   3.988  50.628  1.00 19.70           N  
ATOM    210  CD2 HIS A  38      30.433   4.607  52.005  1.00 18.76           C  
ATOM    211  CE1 HIS A  38      31.112   4.642  49.919  1.00 18.70           C  
ATOM    212  NE2 HIS A  38      30.144   5.035  50.733  1.00 18.74           N  
ATOM    213  N   LEU A  39      33.302   6.521  53.182  1.00 19.22           N  
ATOM    214  CA  LEU A  39      32.840   7.900  53.355  1.00 19.45           C  
ATOM    215  C   LEU A  39      31.868   8.330  52.266  1.00 19.85           C  
ATOM    216  O   LEU A  39      30.781   8.843  52.553  1.00 19.10           O  
ATOM    217  CB  LEU A  39      34.043   8.833  53.376  1.00 19.73           C  
ATOM    218  CG  LEU A  39      33.815  10.340  53.544  1.00 20.03           C  
ATOM    219  CD1 LEU A  39      33.035  10.664  54.805  1.00 20.86           C  
ATOM    220  CD2 LEU A  39      35.149  11.064  53.565  1.00 19.79           C  
ATOM    221  N   CYS A  40      32.261   8.113  51.010  1.00 19.51           N  
ATOM    222  CA  CYS A  40      31.485   8.584  49.875  1.00 19.55           C  
ATOM    223  C   CYS A  40      31.786   7.775  48.629  1.00 17.89           C  
ATOM    224  O   CYS A  40      32.781   7.072  48.561  1.00 17.34           O  
ATOM    225  CB  CYS A  40      31.805  10.059  49.604  1.00 20.17           C  
ATOM    226  SG  CYS A  40      30.822  11.232  50.557  1.00 21.66           S  
ATOM    227  N   GLY A  41      30.888   7.869  47.658  1.00 17.35           N  
ATOM    228  CA  GLY A  41      31.170   7.398  46.321  1.00 16.93           C  
ATOM    229  C   GLY A  41      31.972   8.441  45.561  1.00 16.44           C  
ATOM    230  O   GLY A  41      32.166   9.568  46.035  1.00 16.43           O  
ATOM    231  N   GLY A  42      32.392   8.067  44.355  1.00 16.50           N  
ATOM    232  CA  GLY A  42      33.006   9.002  43.413  1.00 16.52           C  
ATOM    233  C   GLY A  42      33.189   8.314  42.071  1.00 16.90           C  
ATOM    234  O   GLY A  42      32.934   7.109  41.957  1.00 17.07           O  
ATOM    235  N   SER A  43      33.667   9.070  41.081  1.00 16.60           N  
ATOM    236  CA  SER A  43      33.823   8.585  39.705  1.00 17.32           C  
ATOM    237  C   SER A  43      35.227   8.901  39.144  1.00 18.11           C  
ATOM    238  O   SER A  43      35.711  10.029  39.253  1.00 17.71           O  
ATOM    239  CB  SER A  43      32.794   9.245  38.798  1.00 17.77           C  
ATOM    240  OG  SER A  43      31.486   8.958  39.197  1.00 17.48           O  
ATOM    241  N   ILE A  44      35.850   7.899  38.527  1.00 18.43           N  
ATOM    242  CA  ILE A  44      37.115   8.088  37.823  1.00 18.69           C  
ATOM    243  C   ILE A  44      36.822   8.882  36.565  1.00 19.16           C  
ATOM    244  O   ILE A  44      36.009   8.461  35.744  1.00 18.91           O  
ATOM    245  CB  ILE A  44      37.751   6.733  37.431  1.00 19.45           C  
ATOM    246  CG1 ILE A  44      38.053   5.889  38.674  1.00 19.41           C  
ATOM    247  CG2 ILE A  44      39.039   6.951  36.648  1.00 19.80           C  
ATOM    248  CD1 ILE A  44      38.482   4.459  38.382  1.00 18.91           C  
ATOM    249  N   ILE A  45      37.442  10.049  36.430  1.00 20.47           N  
ATOM    250  CA  ILE A  45      37.278  10.857  35.223  1.00 21.04           C  
ATOM    251  C   ILE A  45      38.588  11.103  34.482  1.00 22.72           C  
ATOM    252  O   ILE A  45      38.569  11.575  33.347  1.00 23.69           O  
ATOM    253  CB  ILE A  45      36.566  12.198  35.486  1.00 20.79           C  
ATOM    254  CG1 ILE A  45      37.346  13.069  36.465  1.00 21.12           C  
ATOM    255  CG2 ILE A  45      35.139  11.944  35.956  1.00 20.45           C  
ATOM    256  CD1 ILE A  45      36.890  14.525  36.467  1.00 21.46           C  
ATOM    257  N   GLY A  46      39.705  10.796  35.124  1.00 22.66           N  
ATOM    258  CA  GLY A  46      41.021  10.862  34.496  1.00 24.21           C  
ATOM    259  C   GLY A  46      41.982   9.993  35.271  1.00 25.43           C  
ATOM    260  O   GLY A  46      41.624   9.437  36.311  1.00 24.93           O  
ATOM    261  N   ASN A  47      43.204   9.897  34.775  1.00 26.05           N  
ATOM    262  CA  ASN A  47      44.195   8.981  35.325  1.00 29.37           C  
ATOM    263  C   ASN A  47      44.573   9.290  36.761  1.00 26.42           C  
ATOM    264  O   ASN A  47      44.934   8.399  37.511  1.00 27.43           O  
ATOM    265  CB  ASN A  47      45.453   8.963  34.438  1.00 33.51           C  
ATOM    266  CG  ASN A  47      45.319   8.002  33.269  1.00 38.64           C  
ATOM    267  OD1 ASN A  47      45.010   8.410  32.145  1.00 40.79           O  
ATOM    268  ND2 ASN A  47      45.533   6.704  33.535  1.00 41.04           N  
ATOM    269  N   GLN A  48      44.469  10.558  37.139  1.00 24.84           N  
ATOM    270  CA  GLN A  48      44.802  10.997  38.475  1.00 26.37           C  
ATOM    271  C   GLN A  48      43.621  11.679  39.192  1.00 22.75           C  
ATOM    272  O   GLN A  48      43.804  12.338  40.207  1.00 22.18           O  
ATOM    273  CB  GLN A  48      45.961  11.983  38.358  1.00 29.90           C  
ATOM    274  CG  GLN A  48      47.002  11.818  39.424  1.00 35.59           C  
ATOM    275  CD  GLN A  48      48.133  12.814  39.276  1.00 39.11           C  
ATOM    276  OE1 GLN A  48      48.284  13.459  38.232  1.00 40.85           O  
ATOM    277  NE2 GLN A  48      48.925  12.955  40.325  1.00 41.31           N  
ATOM    278  N   TRP A  51      42.412  11.516  38.666  1.00 22.66           N  
ATOM    279  CA  TRP A  51      41.299  12.362  39.063  1.00 22.52           C  
ATOM    280  C   TRP A  51      40.012  11.616  39.366  1.00 20.66           C  
ATOM    281  O   TRP A  51      39.474  10.893  38.517  1.00 19.49           O  
ATOM    282  CB  TRP A  51      41.012  13.403  37.976  1.00 23.09           C  
ATOM    283  CG  TRP A  51      42.160  14.329  37.755  1.00 23.77           C  
ATOM    284  CD1 TRP A  51      43.074  14.270  36.745  1.00 24.94           C  
ATOM    285  CD2 TRP A  51      42.510  15.447  38.555  1.00 23.71           C  
ATOM    286  NE1 TRP A  51      43.983  15.288  36.874  1.00 24.41           N  
ATOM    287  CE2 TRP A  51      43.654  16.034  37.975  1.00 25.28           C  
ATOM    288  CE3 TRP A  51      41.971  16.019  39.713  1.00 24.06           C  
ATOM    289  CZ2 TRP A  51      44.276  17.162  38.518  1.00 24.94           C  
ATOM    290  CZ3 TRP A  51      42.580  17.146  40.247  1.00 25.22           C  
ATOM    291  CH2 TRP A  51      43.729  17.705  39.643  1.00 25.26           C  
ATOM    292  N   ILE A  52      39.498  11.855  40.573  1.00 18.79           N  
ATOM    293  CA  ILE A  52      38.155  11.407  40.957  1.00 18.13           C  
ATOM    294  C   ILE A  52      37.242  12.618  41.073  1.00 17.37           C  
ATOM    295  O   ILE A  52      37.643  13.624  41.643  1.00 18.60           O  
ATOM    296  CB  ILE A  52      38.184  10.712  42.328  1.00 18.45           C  
ATOM    297  CG1 ILE A  52      39.206   9.569  42.347  1.00 18.75           C  
ATOM    298  CG2 ILE A  52      36.792  10.251  42.726  1.00 18.49           C  
ATOM    299  CD1 ILE A  52      38.931   8.443  41.363  1.00 18.92           C  
ATOM    300  N   LEU A  53      36.027  12.520  40.544  1.00 17.08           N  
ATOM    301  CA  LEU A  53      35.014  13.550  40.721  1.00 17.56           C  
ATOM    302  C   LEU A  53      34.001  13.053  41.750  1.00 17.44           C  
ATOM    303  O   LEU A  53      33.542  11.918  41.676  1.00 18.00           O  
ATOM    304  CB  LEU A  53      34.309  13.867  39.406  1.00 17.43           C  
ATOM    305  CG  LEU A  53      33.518  15.172  39.357  1.00 17.84           C  
ATOM    306  CD1 LEU A  53      34.433  16.387  39.373  1.00 18.00           C  
ATOM    307  CD2 LEU A  53      32.644  15.207  38.116  1.00 18.73           C  
ATOM    308  N   THR A  54      33.667  13.917  42.699  1.00 17.96           N  
ATOM    309  CA  THR A  54      32.832  13.539  43.819  1.00 18.92           C  
ATOM    310  C   THR A  54      32.096  14.784  44.349  1.00 18.90           C  
ATOM    311  O   THR A  54      32.089  15.832  43.691  1.00 19.20           O  
ATOM    312  CB  THR A  54      33.690  12.812  44.897  1.00 18.83           C  
ATOM    313  OG1 THR A  54      32.851  12.343  45.965  1.00 19.29           O  
ATOM    314  CG2 THR A  54      34.776  13.727  45.444  1.00 18.72           C  
ATOM    315  N   ALA A  55      31.446  14.668  45.506  1.00 19.21           N  
ATOM    316  CA  ALA A  55      30.680  15.796  46.075  1.00 19.15           C  
ATOM    317  C   ALA A  55      31.506  16.561  47.104  1.00 19.14           C  
ATOM    318  O   ALA A  55      32.268  15.975  47.865  1.00 19.68           O  
ATOM    319  CB  ALA A  55      29.349  15.325  46.692  1.00 19.77           C  
ATOM    320  N   ALA A  56      31.382  17.882  47.076  1.00 19.61           N  
ATOM    321  CA  ALA A  56      32.080  18.751  48.018  1.00 19.49           C  
ATOM    322  C   ALA A  56      31.697  18.456  49.460  1.00 18.82           C  
ATOM    323  O   ALA A  56      32.543  18.558  50.357  1.00 18.42           O  
ATOM    324  CB  ALA A  56      31.789  20.214  47.706  1.00 19.23           C  
ATOM    325  N   HIS A  57      30.434  18.117  49.699  1.00 18.56           N  
ATOM    326  CA  HIS A  57      29.984  17.943  51.087  1.00 19.34           C  
ATOM    327  C   HIS A  57      30.627  16.743  51.762  1.00 19.54           C  
ATOM    328  O   HIS A  57      30.572  16.612  52.981  1.00 19.92           O  
ATOM    329  CB  HIS A  57      28.466  17.831  51.170  1.00 19.66           C  
ATOM    330  CG  HIS A  57      27.941  16.519  50.687  1.00 19.62           C  
ATOM    331  ND1 HIS A  57      27.278  16.383  49.488  1.00 18.87           N  
ATOM    332  CD2 HIS A  57      28.012  15.275  51.223  1.00 20.90           C  
ATOM    333  CE1 HIS A  57      26.931  15.119  49.321  1.00 19.74           C  
ATOM    334  NE2 HIS A  57      27.378  14.422  50.352  1.00 20.54           N  
ATOM    335  N   CYS A  58      31.225  15.853  50.976  1.00 19.78           N  
ATOM    336  CA  CYS A  58      31.887  14.676  51.534  1.00 20.17           C  
ATOM    337  C   CYS A  58      33.050  15.019  52.458  1.00 20.33           C  
ATOM    338  O   CYS A  58      33.467  14.181  53.257  1.00 21.60           O  
ATOM    339  CB  CYS A  58      32.388  13.758  50.421  1.00 19.68           C  
ATOM    340  SG  CYS A  58      31.054  12.958  49.538  1.00 20.12           S  
ATOM    341  N   PHE A  59      33.570  16.240  52.357  1.00 20.73           N  
ATOM    342  CA  PHE A  59      34.772  16.619  53.093  1.00 21.40           C  
ATOM    343  C   PHE A  59      34.518  17.515  54.278  1.00 21.37           C  
ATOM    344  O   PHE A  59      35.432  18.156  54.792  1.00 22.63           O  
ATOM    345  CB  PHE A  59      35.772  17.200  52.102  1.00 21.96           C  
ATOM    346  CG  PHE A  59      35.996  16.271  50.961  1.00 21.89           C  
ATOM    347  CD1 PHE A  59      36.791  15.148  51.135  1.00 22.94           C  
ATOM    348  CD2 PHE A  59      35.306  16.433  49.770  1.00 22.55           C  
ATOM    349  CE1 PHE A  59      36.945  14.229  50.120  1.00 22.77           C  
ATOM    350  CE2 PHE A  59      35.452  15.514  48.748  1.00 21.74           C  
ATOM    351  CZ  PHE A  59      36.267  14.416  48.921  1.00 23.08           C  
ATOM    352  N   TYR A  59A     33.277  17.537  54.736  1.00 22.85           N  
ATOM    353  CA  TYR A  59A     32.958  18.272  55.941  1.00 24.40           C  
ATOM    354  C   TYR A  59A     33.861  17.782  57.071  1.00 24.04           C  
ATOM    355  O   TYR A  59A     33.952  16.586  57.309  1.00 25.80           O  
ATOM    356  CB  TYR A  59A     31.495  18.069  56.328  1.00 25.27           C  
ATOM    357  CG  TYR A  59A     31.200  18.689  57.654  1.00 26.66           C  
ATOM    358  CD1 TYR A  59A     31.003  20.064  57.753  1.00 28.22           C  
ATOM    359  CD2 TYR A  59A     31.185  17.929  58.820  1.00 27.79           C  
ATOM    360  CE1 TYR A  59A     30.767  20.660  58.968  1.00 28.63           C  
ATOM    361  CE2 TYR A  59A     30.950  18.526  60.046  1.00 29.25           C  
ATOM    362  CZ  TYR A  59A     30.740  19.894  60.099  1.00 29.25           C  
ATOM    363  OH  TYR A  59A     30.504  20.529  61.286  1.00 32.36           O  
ATOM    364  N   GLY A  59B     34.558  18.694  57.738  1.00 25.64           N  
ATOM    365  CA  GLY A  59B     35.444  18.318  58.842  1.00 26.98           C  
ATOM    366  C   GLY A  59B     36.729  17.591  58.465  1.00 29.12           C  
ATOM    367  O   GLY A  59B     37.528  17.264  59.348  1.00 30.08           O  
ATOM    368  N   VAL A  59C     36.936  17.311  57.172  1.00 28.15           N  
ATOM    369  CA  VAL A  59C     38.155  16.629  56.719  1.00 28.73           C  
ATOM    370  C   VAL A  59C     39.250  17.682  56.648  1.00 31.09           C  
ATOM    371  O   VAL A  59C     39.172  18.608  55.849  1.00 33.61           O  
ATOM    372  CB  VAL A  59C     37.961  15.918  55.353  1.00 28.23           C  
ATOM    373  CG1 VAL A  59C     39.275  15.371  54.804  1.00 27.00           C  
ATOM    374  CG2 VAL A  59C     36.958  14.782  55.486  1.00 26.15           C  
ATOM    375  N   GLU A  60      40.253  17.553  57.514  1.00 33.22           N  
ATOM    376  CA  GLU A  60      41.273  18.590  57.690  1.00 32.90           C  
ATOM    377  C   GLU A  60      42.472  18.398  56.788  1.00 32.50           C  
ATOM    378  O   GLU A  60      43.243  19.330  56.560  1.00 33.97           O  
ATOM    379  CB  GLU A  60      41.745  18.619  59.151  1.00 34.02           C  
ATOM    380  CG  GLU A  60      40.668  19.017  60.144  0.50 35.08           C  
ATOM    381  CD  GLU A  60      40.345  20.491  60.086  0.50 35.10           C  
ATOM    382  OE1 GLU A  60      40.230  21.031  58.968  0.50 35.31           O  
ATOM    383  OE2 GLU A  60      40.209  21.109  61.162  0.50 35.16           O  
ATOM    384  N   SER A  61      42.635  17.184  56.283  1.00 30.83           N  
ATOM    385  CA  SER A  61      43.802  16.839  55.506  1.00 30.88           C  
ATOM    386  C   SER A  61      43.453  15.683  54.571  1.00 30.48           C  
ATOM    387  O   SER A  61      42.669  14.817  54.947  1.00 30.28           O  
ATOM    388  CB  SER A  61      44.928  16.446  56.462  1.00 30.86           C  
ATOM    389  OG  SER A  61      45.913  15.654  55.831  1.00 30.01           O  
ATOM    390  N   PRO A  62      44.041  15.663  53.361  1.00 30.05           N  
ATOM    391  CA  PRO A  62      43.864  14.532  52.440  1.00 29.72           C  
ATOM    392  C   PRO A  62      44.585  13.246  52.883  1.00 30.56           C  
ATOM    393  O   PRO A  62      44.380  12.182  52.292  1.00 29.99           O  
ATOM    394  CB  PRO A  62      44.455  15.052  51.124  1.00 29.53           C  
ATOM    395  CG  PRO A  62      45.404  16.126  51.517  1.00 29.97           C  
ATOM    396  CD  PRO A  62      44.846  16.746  52.761  1.00 29.73           C  
ATOM    397  N   LYS A  63      45.399  13.342  53.933  1.00 30.01           N  
ATOM    398  CA  LYS A  63      46.212  12.220  54.378  1.00 30.42           C  
ATOM    399  C   LYS A  63      45.377  11.101  54.983  1.00 28.04           C  
ATOM    400  O   LYS A  63      45.829   9.967  55.048  1.00 29.39           O  
ATOM    401  CB  LYS A  63      47.259  12.703  55.391  1.00 33.03           C  
ATOM    402  CG  LYS A  63      48.165  13.791  54.841  1.00 36.93           C  
ATOM    403  CD  LYS A  63      49.102  14.355  55.897  1.00 40.17           C  
ATOM    404  CE  LYS A  63      49.953  15.466  55.299  1.00 42.73           C  
ATOM    405  NZ  LYS A  63      51.257  15.583  56.007  1.00 45.69           N  
ATOM    406  N   ILE A  64      44.166  11.416  55.427  1.00 26.71           N  
ATOM    407  CA  ILE A  64      43.263  10.408  56.000  1.00 26.46           C  
ATOM    408  C   ILE A  64      42.363   9.712  54.967  1.00 24.48           C  
ATOM    409  O   ILE A  64      41.534   8.883  55.342  1.00 25.93           O  
ATOM    410  CB  ILE A  64      42.373  10.994  57.124  1.00 27.26           C  
ATOM    411  CG1 ILE A  64      41.457  12.103  56.601  1.00 27.37           C  
ATOM    412  CG2 ILE A  64      43.233  11.505  58.273  1.00 28.59           C  
ATOM    413  CD1 ILE A  64      40.367  12.490  57.572  1.00 27.76           C  
ATOM    414  N   LEU A  65      42.523  10.030  53.683  1.00 22.74           N  
ATOM    415  CA  LEU A  65      41.642   9.481  52.638  1.00 21.85           C  
ATOM    416  C   LEU A  65      42.297   8.360  51.870  1.00 21.57           C  
ATOM    417  O   LEU A  65      43.494   8.378  51.642  1.00 22.26           O  
ATOM    418  CB  LEU A  65      41.232  10.571  51.647  1.00 21.71           C  
ATOM    419  CG  LEU A  65      40.423  11.732  52.226  1.00 21.90           C  
ATOM    420  CD1 LEU A  65      40.238  12.803  51.164  1.00 22.32           C  
ATOM    421  CD2 LEU A  65      39.073  11.262  52.750  1.00 21.93           C  
ATOM    422  N   ARG A  66      41.489   7.402  51.444  1.00 20.92           N  
ATOM    423  CA  ARG A  66      41.944   6.302  50.617  1.00 21.16           C  
ATOM    424  C   ARG A  66      40.884   6.032  49.559  1.00 21.13           C  
ATOM    425  O   ARG A  66      39.697   5.892  49.878  1.00 19.99           O  
ATOM    426  CB  ARG A  66      42.144   5.051  51.463  1.00 22.24           C  
ATOM    427  CG  ARG A  66      43.262   5.181  52.487  1.00 23.03           C  
ATOM    428  CD  ARG A  66      43.453   3.864  53.199  1.00 25.09           C  
ATOM    429  NE  ARG A  66      44.718   3.828  53.925  1.00 26.03           N  
ATOM    430  CZ  ARG A  66      45.232   2.741  54.497  1.00 27.87           C  
ATOM    431  NH1 ARG A  66      44.591   1.575  54.448  1.00 28.83           N  
ATOM    432  NH2 ARG A  66      46.404   2.811  55.116  1.00 27.56           N  
ATOM    433  N   VAL A  67      41.305   6.005  48.300  1.00 20.31           N  
ATOM    434  CA  VAL A  67      40.406   5.689  47.194  1.00 20.20           C  
ATOM    435  C   VAL A  67      40.649   4.258  46.726  1.00 19.93           C  
ATOM    436  O   VAL A  67      41.793   3.887  46.414  1.00 20.63           O  
ATOM    437  CB  VAL A  67      40.608   6.674  46.029  1.00 20.74           C  
ATOM    438  CG1 VAL A  67      39.719   6.328  44.839  1.00 21.29           C  
ATOM    439  CG2 VAL A  67      40.325   8.082  46.516  1.00 22.46           C  
ATOM    440  N   TYR A  68      39.579   3.460  46.730  1.00 19.48           N  
ATOM    441  CA  TYR A  68      39.600   2.088  46.239  1.00 19.67           C  
ATOM    442  C   TYR A  68      38.824   1.983  44.927  1.00 20.10           C  
ATOM    443  O   TYR A  68      37.649   2.354  44.853  1.00 19.23           O  
ATOM    444  CB  TYR A  68      39.007   1.119  47.257  1.00 20.47           C  
ATOM    445  CG  TYR A  68      39.796   1.016  48.539  1.00 20.45           C  
ATOM    446  CD1 TYR A  68      39.541   1.874  49.593  1.00 21.52           C  
ATOM    447  CD2 TYR A  68      40.797   0.058  48.694  1.00 21.15           C  
ATOM    448  CE1 TYR A  68      40.264   1.805  50.770  1.00 21.19           C  
ATOM    449  CE2 TYR A  68      41.529  -0.031  49.874  1.00 21.33           C  
ATOM    450  CZ  TYR A  68      41.256   0.857  50.909  1.00 21.15           C  
ATOM    451  OH  TYR A  68      41.956   0.798  52.095  1.00 21.67           O  
ATOM    452  N   SER A  69      39.495   1.473  43.896  1.00 19.86           N  
ATOM    453  CA  SER A  69      38.881   1.245  42.599  1.00 20.19           C  
ATOM    454  C   SER A  69      38.757  -0.242  42.358  1.00 20.69           C  
ATOM    455  O   SER A  69      39.402  -1.041  43.035  1.00 23.16           O  
ATOM    456  CB  SER A  69      39.720   1.872  41.484  1.00 20.45           C  
ATOM    457  OG  SER A  69      41.002   1.273  41.415  1.00 20.57           O  
ATOM    458  N   GLY A  70      37.895  -0.610  41.416  1.00 21.22           N  
ATOM    459  CA  GLY A  70      37.714  -2.000  41.037  1.00 22.00           C  
ATOM    460  C   GLY A  70      37.126  -2.838  42.160  1.00 21.77           C  
ATOM    461  O   GLY A  70      37.477  -4.009  42.320  1.00 20.97           O  
ATOM    462  N   ILE A  71      36.248  -2.223  42.945  1.00 21.13           N  
ATOM    463  CA  ILE A  71      35.619  -2.890  44.066  1.00 21.60           C  
ATOM    464  C   ILE A  71      34.164  -3.196  43.746  1.00 21.59           C  
ATOM    465  O   ILE A  71      33.424  -2.328  43.256  1.00 21.74           O  
ATOM    466  CB  ILE A  71      35.661  -2.013  45.341  1.00 22.15           C  
ATOM    467  CG1 ILE A  71      37.091  -1.565  45.650  1.00 22.82           C  
ATOM    468  CG2 ILE A  71      35.022  -2.738  46.518  1.00 23.18           C  
ATOM    469  CD1 ILE A  71      38.066  -2.646  46.062  1.00 23.08           C  
ATOM    470  N   LEU A  72      33.748  -4.422  44.061  1.00 21.04           N  
ATOM    471  CA  LEU A  72      32.333  -4.767  44.088  1.00 21.47           C  
ATOM    472  C   LEU A  72      31.822  -4.788  45.528  1.00 21.65           C  
ATOM    473  O   LEU A  72      30.847  -4.116  45.856  1.00 20.74           O  
ATOM    474  CB  LEU A  72      32.079  -6.134  43.438  1.00 22.59           C  
ATOM    475  CG  LEU A  72      30.610  -6.574  43.447  1.00 22.93           C  
ATOM    476  CD1 LEU A  72      29.753  -5.611  42.646  1.00 22.50           C  
ATOM    477  CD2 LEU A  72      30.471  -7.981  42.893  1.00 23.31           C  
ATOM    478  N   ASN A  73      32.476  -5.592  46.360  1.00 21.33           N  
ATOM    479  CA  ASN A  73      32.084  -5.785  47.748  1.00 23.02           C  
ATOM    480  C   ASN A  73      33.058  -5.107  48.700  1.00 22.65           C  
ATOM    481  O   ASN A  73      34.275  -5.250  48.561  1.00 21.96           O  
ATOM    482  CB  ASN A  73      32.010  -7.273  48.075  1.00 23.99           C  
ATOM    483  CG  ASN A  73      30.984  -8.005  47.231  1.00 25.86           C  
ATOM    484  OD1 ASN A  73      29.816  -7.647  47.213  1.00 27.85           O  
ATOM    485  ND2 ASN A  73      31.419  -9.033  46.521  1.00 26.61           N  
ATOM    486  N   GLN A  74      32.524  -4.386  49.685  1.00 22.89           N  
ATOM    487  CA  GLN A  74      33.355  -3.731  50.703  1.00 22.34           C  
ATOM    488  C   GLN A  74      34.239  -4.740  51.440  1.00 22.23           C  
ATOM    489  O   GLN A  74      35.322  -4.387  51.907  1.00 22.38           O  
ATOM    490  CB  GLN A  74      32.495  -2.941  51.712  1.00 22.32           C  
ATOM    491  CG  GLN A  74      31.817  -1.705  51.137  1.00 21.65           C  
ATOM    492  CD  GLN A  74      32.768  -0.539  50.909  1.00 21.42           C  
ATOM    493  OE1 GLN A  74      33.798  -0.417  51.561  1.00 21.21           O  
ATOM    494  NE2 GLN A  74      32.415   0.331  49.974  1.00 21.11           N  
ATOM    495  N   ALA A  75      33.790  -5.991  51.530  1.00 24.00           N  
ATOM    496  CA  ALA A  75      34.597  -7.077  52.120  1.00 24.28           C  
ATOM    497  C   ALA A  75      35.940  -7.322  51.413  1.00 24.31           C  
ATOM    498  O   ALA A  75      36.880  -7.855  52.013  1.00 25.28           O  
ATOM    499  CB  ALA A  75      33.797  -8.364  52.155  1.00 24.98           C  
ATOM    500  N   GLU A  76      36.041  -6.926  50.149  1.00 23.85           N  
ATOM    501  CA  GLU A  76      37.330  -6.953  49.442  1.00 23.48           C  
ATOM    502  C   GLU A  76      38.408  -6.056  50.058  1.00 22.65           C  
ATOM    503  O   GLU A  76      39.593  -6.225  49.748  1.00 23.55           O  
ATOM    504  CB  GLU A  76      37.151  -6.496  47.987  1.00 22.92           C  
ATOM    505  CG  GLU A  76      36.224  -7.348  47.154  1.00 24.06           C  
ATOM    506  CD  GLU A  76      35.956  -6.724  45.807  1.00 23.64           C  
ATOM    507  OE1 GLU A  76      36.907  -6.224  45.184  1.00 24.03           O  
ATOM    508  OE2 GLU A  76      34.798  -6.723  45.371  1.00 23.98           O  
ATOM    509  N   ILE A  77      37.994  -5.060  50.854  1.00 22.70           N  
ATOM    510  CA  ILE A  77      38.899  -4.071  51.431  1.00 22.74           C  
ATOM    511  C   ILE A  77      39.373  -4.527  52.818  1.00 23.73           C  
ATOM    512  O   ILE A  77      38.597  -4.574  53.775  1.00 23.29           O  
ATOM    513  CB  ILE A  77      38.230  -2.664  51.500  1.00 22.91           C  
ATOM    514  CG1 ILE A  77      37.855  -2.207  50.073  1.00 23.08           C  
ATOM    515  CG2 ILE A  77      39.157  -1.640  52.156  1.00 22.65           C  
ATOM    516  CD1 ILE A  77      37.068  -0.912  49.967  1.00 22.95           C  
ATOM    517  N   ALA A  78      40.651  -4.864  52.896  1.00 23.36           N  
ATOM    518  CA  ALA A  78      41.320  -5.249  54.133  1.00 24.94           C  
ATOM    519  C   ALA A  78      42.534  -4.345  54.310  1.00 25.36           C  
ATOM    520  O   ALA A  78      42.860  -3.568  53.433  1.00 24.76           O  
ATOM    521  CB  ALA A  78      41.744  -6.715  54.075  1.00 25.06           C  
ATOM    522  N   GLU A  79      43.228  -4.469  55.431  1.00 27.19           N  
ATOM    523  CA  GLU A  79      44.437  -3.691  55.641  1.00 28.85           C  
ATOM    524  C   GLU A  79      45.496  -3.941  54.549  1.00 27.76           C  
ATOM    525  O   GLU A  79      46.327  -3.095  54.300  1.00 26.59           O  
ATOM    526  CB  GLU A  79      44.994  -3.951  57.051  1.00 33.07           C  
ATOM    527  CG  GLU A  79      44.185  -3.218  58.135  1.00 37.51           C  
ATOM    528  CD  GLU A  79      44.269  -3.849  59.523  1.00 41.66           C  
ATOM    529  OE1 GLU A  79      45.287  -4.505  59.824  1.00 44.44           O  
ATOM    530  OE2 GLU A  79      43.303  -3.682  60.315  1.00 44.88           O  
ATOM    531  N   ASP A  80      45.449  -5.100  53.896  1.00 26.88           N  
ATOM    532  CA  ASP A  80      46.431  -5.437  52.859  1.00 26.56           C  
ATOM    533  C   ASP A  80      45.970  -5.115  51.421  1.00 27.10           C  
ATOM    534  O   ASP A  80      46.670  -5.437  50.461  1.00 26.76           O  
ATOM    535  CB  ASP A  80      46.825  -6.921  52.983  1.00 26.38           C  
ATOM    536  CG  ASP A  80      45.689  -7.876  52.632  1.00 26.22           C  
ATOM    537  OD1 ASP A  80      44.533  -7.429  52.434  1.00 25.00           O  
ATOM    538  OD2 ASP A  80      45.945  -9.104  52.545  1.00 26.69           O  
ATOM    539  N   THR A  81      44.812  -4.474  51.274  1.00 24.55           N  
ATOM    540  CA  THR A  81      44.271  -4.133  49.954  1.00 24.01           C  
ATOM    541  C   THR A  81      44.902  -2.844  49.449  1.00 23.89           C  
ATOM    542  O   THR A  81      45.045  -1.897  50.202  1.00 24.21           O  
ATOM    543  CB  THR A  81      42.742  -3.962  50.013  1.00 22.21           C  
ATOM    544  OG1 THR A  81      42.152  -5.164  50.515  1.00 21.10           O  
ATOM    545  CG2 THR A  81      42.151  -3.637  48.623  1.00 22.05           C  
ATOM    546  N   SER A  81A     45.269  -2.800  48.171  1.00 24.68           N  
ATOM    547  CA  SER A  81A     45.955  -1.628  47.637  1.00 25.42           C  
ATOM    548  C   SER A  81A     44.954  -0.489  47.391  1.00 25.03           C  
ATOM    549  O   SER A  81A     43.769  -0.719  47.161  1.00 24.55           O  
ATOM    550  CB  SER A  81A     46.740  -1.967  46.367  1.00 27.28           C  
ATOM    551  OG  SER A  81A     45.874  -2.198  45.276  1.00 28.59           O  
ATOM    552  N   PHE A  82      45.431   0.743  47.489  1.00 23.93           N  
ATOM    553  CA  PHE A  82      44.551   1.891  47.343  1.00 24.90           C  
ATOM    554  C   PHE A  82      45.307   3.054  46.742  1.00 23.74           C  
ATOM    555  O   PHE A  82      46.524   3.022  46.650  1.00 23.62           O  
ATOM    556  CB  PHE A  82      43.989   2.289  48.711  1.00 25.34           C  
ATOM    557  CG  PHE A  82      45.046   2.684  49.699  1.00 26.14           C  
ATOM    558  CD1 PHE A  82      45.530   3.990  49.738  1.00 26.89           C  
ATOM    559  CD2 PHE A  82      45.581   1.753  50.572  1.00 27.12           C  
ATOM    560  CE1 PHE A  82      46.517   4.351  50.631  1.00 28.77           C  
ATOM    561  CE2 PHE A  82      46.566   2.116  51.470  1.00 27.15           C  
ATOM    562  CZ  PHE A  82      47.037   3.408  51.503  1.00 27.06           C  
ATOM    563  N   PHE A  83      44.574   4.089  46.355  1.00 22.92           N  
ATOM    564  CA  PHE A  83      45.180   5.334  45.909  1.00 22.78           C  
ATOM    565  C   PHE A  83      45.149   6.377  47.006  1.00 23.14           C  
ATOM    566  O   PHE A  83      44.102   6.677  47.568  1.00 21.91           O  
ATOM    567  CB  PHE A  83      44.474   5.861  44.669  1.00 22.95           C  
ATOM    568  CG  PHE A  83      44.550   4.924  43.518  1.00 22.85           C  
ATOM    569  CD1 PHE A  83      45.617   4.971  42.649  1.00 23.71           C  
ATOM    570  CD2 PHE A  83      43.577   3.946  43.340  1.00 23.55           C  
ATOM    571  CE1 PHE A  83      45.703   4.077  41.593  1.00 24.48           C  
ATOM    572  CE2 PHE A  83      43.656   3.047  42.296  1.00 22.64           C  
ATOM    573  CZ  PHE A  83      44.722   3.115  41.418  1.00 25.00           C  
ATOM    574  N   GLY A  84      46.318   6.930  47.313  1.00 22.81           N  
ATOM    575  CA  GLY A  84      46.402   8.064  48.214  1.00 23.82           C  
ATOM    576  C   GLY A  84      45.872   9.308  47.525  1.00 24.81           C  
ATOM    577  O   GLY A  84      45.857   9.387  46.293  1.00 23.80           O  
ATOM    578  N   VAL A  85      45.417  10.265  48.328  1.00 24.92           N  
ATOM    579  CA  VAL A  85      44.943  11.547  47.816  1.00 26.11           C  
ATOM    580  C   VAL A  85      45.968  12.636  48.121  1.00 27.55           C  
ATOM    581  O   VAL A  85      46.351  12.847  49.279  1.00 27.22           O  
ATOM    582  CB  VAL A  85      43.580  11.934  48.414  1.00 25.88           C  
ATOM    583  CG1 VAL A  85      43.131  13.295  47.902  1.00 26.45           C  
ATOM    584  CG2 VAL A  85      42.533  10.875  48.089  1.00 26.18           C  
ATOM    585  N   GLN A  86      46.388  13.325  47.068  1.00 27.20           N  
ATOM    586  CA  GLN A  86      47.388  14.383  47.144  1.00 29.82           C  
ATOM    587  C   GLN A  86      46.740  15.731  47.422  1.00 28.93           C  
ATOM    588  O   GLN A  86      47.309  16.590  48.097  1.00 27.93           O  
ATOM    589  CB  GLN A  86      48.120  14.423  45.809  1.00 32.82           C  
ATOM    590  CG  GLN A  86      49.258  15.401  45.692  1.00 36.17           C  
ATOM    591  CD  GLN A  86      49.742  15.495  44.264  1.00 37.87           C  
ATOM    592  OE1 GLN A  86      49.873  16.579  43.718  1.00 42.78           O  
ATOM    593  NE2 GLN A  86      49.974  14.353  43.642  1.00 39.19           N  
ATOM    594  N   GLU A  87      45.540  15.922  46.893  1.00 26.89           N  
ATOM    595  CA  GLU A  87      44.872  17.190  47.009  1.00 27.37           C  
ATOM    596  C   GLU A  87      43.371  17.032  46.903  1.00 24.90           C  
ATOM    597  O   GLU A  87      42.886  16.280  46.074  1.00 24.05           O  
ATOM    598  CB  GLU A  87      45.364  18.115  45.897  1.00 28.63           C  
ATOM    599  CG  GLU A  87      45.033  19.572  46.124  1.00 30.27           C  
ATOM    600  CD  GLU A  87      45.355  20.440  44.924  1.00 31.01           C  
ATOM    601  OE1 GLU A  87      46.129  20.005  44.046  1.00 33.17           O  
ATOM    602  OE2 GLU A  87      44.832  21.565  44.865  1.00 34.69           O  
ATOM    603  N   ILE A  88      42.650  17.747  47.762  1.00 24.03           N  
ATOM    604  CA  ILE A  88      41.210  17.891  47.645  1.00 23.72           C  
ATOM    605  C   ILE A  88      40.938  19.272  47.050  1.00 24.20           C  
ATOM    606  O   ILE A  88      41.341  20.271  47.638  1.00 24.31           O  
ATOM    607  CB  ILE A  88      40.516  17.819  49.020  1.00 23.29           C  
ATOM    608  CG1 ILE A  88      40.829  16.490  49.727  1.00 23.49           C  
ATOM    609  CG2 ILE A  88      39.008  18.022  48.867  1.00 23.87           C  
ATOM    610  CD1 ILE A  88      40.701  16.552  51.231  1.00 23.55           C  
ATOM    611  N   ILE A  89      40.250  19.335  45.910  1.00 23.47           N  
ATOM    612  CA  ILE A  89      39.858  20.626  45.308  1.00 24.04           C  
ATOM    613  C   ILE A  89      38.340  20.803  45.360  1.00 23.19           C  
ATOM    614  O   ILE A  89      37.611  20.138  44.635  1.00 23.13           O  
ATOM    615  CB  ILE A  89      40.290  20.743  43.832  1.00 24.96           C  
ATOM    616  CG1 ILE A  89      41.795  20.462  43.660  1.00 26.14           C  
ATOM    617  CG2 ILE A  89      39.927  22.115  43.293  1.00 25.03           C  
ATOM    618  CD1 ILE A  89      42.224  20.316  42.207  1.00 26.97           C  
ATOM    619  N   ILE A  90      37.867  21.709  46.209  1.00 22.85           N  
ATOM    620  CA  ILE A  90      36.434  21.964  46.336  1.00 24.30           C  
ATOM    621  C   ILE A  90      36.075  23.262  45.607  1.00 24.70           C  
ATOM    622  O   ILE A  90      36.805  24.241  45.705  1.00 24.65           O  
ATOM    623  CB  ILE A  90      36.035  22.038  47.821  1.00 26.30           C  
ATOM    624  CG1 ILE A  90      36.125  20.632  48.433  1.00 27.77           C  
ATOM    625  CG2 ILE A  90      34.628  22.609  47.994  1.00 26.05           C  
ATOM    626  CD1 ILE A  90      36.011  20.592  49.932  1.00 29.11           C  
ATOM    627  N   HIS A  91      34.958  23.260  44.886  1.00 25.52           N  
ATOM    628  CA  HIS A  91      34.495  24.440  44.153  1.00 25.60           C  
ATOM    629  C   HIS A  91      34.457  25.662  45.077  1.00 26.43           C  
ATOM    630  O   HIS A  91      33.925  25.595  46.186  1.00 24.17           O  
ATOM    631  CB  HIS A  91      33.114  24.194  43.553  1.00 25.95           C  
ATOM    632  CG  HIS A  91      32.769  25.123  42.431  1.00 26.22           C  
ATOM    633  ND1 HIS A  91      32.573  26.472  42.619  1.00 27.56           N  
ATOM    634  CD2 HIS A  91      32.587  24.899  41.106  1.00 25.99           C  
ATOM    635  CE1 HIS A  91      32.281  27.043  41.464  1.00 27.07           C  
ATOM    636  NE2 HIS A  91      32.291  26.112  40.527  1.00 27.44           N  
ATOM    637  N   ASP A  92      35.033  26.781  44.644  1.00 27.86           N  
ATOM    638  CA  ASP A  92      35.210  27.910  45.579  1.00 30.92           C  
ATOM    639  C   ASP A  92      33.889  28.600  45.972  1.00 30.05           C  
ATOM    640  O   ASP A  92      33.854  29.379  46.938  1.00 29.94           O  
ATOM    641  CB  ASP A  92      36.242  28.922  45.055  1.00 35.76           C  
ATOM    642  CG  ASP A  92      35.769  29.665  43.832  1.00 38.88           C  
ATOM    643  OD1 ASP A  92      34.566  29.609  43.531  1.00 44.84           O  
ATOM    644  OD2 ASP A  92      36.609  30.303  43.161  1.00 45.17           O  
ATOM    645  N   GLN A  93      32.820  28.304  45.234  1.00 27.22           N  
ATOM    646  CA  GLN A  93      31.476  28.817  45.526  1.00 28.22           C  
ATOM    647  C   GLN A  93      30.618  27.863  46.361  1.00 26.18           C  
ATOM    648  O   GLN A  93      29.489  28.209  46.732  1.00 25.03           O  
ATOM    649  CB  GLN A  93      30.741  29.154  44.231  1.00 30.86           C  
ATOM    650  CG  GLN A  93      31.320  30.352  43.500  1.00 32.99           C  
ATOM    651  CD  GLN A  93      30.540  30.682  42.248  1.00 35.44           C  
ATOM    652  OE1 GLN A  93      29.414  31.163  42.327  1.00 39.64           O  
ATOM    653  NE2 GLN A  93      31.130  30.423  41.082  1.00 35.26           N  
ATOM    654  N   TYR A  94      31.154  26.684  46.667  1.00 23.63           N  
ATOM    655  CA  TYR A  94      30.433  25.703  47.475  1.00 23.77           C  
ATOM    656  C   TYR A  94      30.266  26.185  48.918  1.00 23.52           C  
ATOM    657  O   TYR A  94      31.218  26.625  49.553  1.00 22.26           O  
ATOM    658  CB  TYR A  94      31.136  24.337  47.484  1.00 23.15           C  
ATOM    659  CG  TYR A  94      30.549  23.414  48.524  1.00 23.38           C  
ATOM    660  CD1 TYR A  94      29.349  22.766  48.301  1.00 23.32           C  
ATOM    661  CD2 TYR A  94      31.187  23.220  49.752  1.00 23.58           C  
ATOM    662  CE1 TYR A  94      28.798  21.936  49.264  1.00 24.17           C  
ATOM    663  CE2 TYR A  94      30.640  22.396  50.724  1.00 23.91           C  
ATOM    664  CZ  TYR A  94      29.445  21.760  50.472  1.00 23.87           C  
ATOM    665  OH  TYR A  94      28.893  20.942  51.428  1.00 24.29           O  
ATOM    666  N   LYS A  95      29.046  26.066  49.418  1.00 24.75           N  
ATOM    667  CA  LYS A  95      28.737  26.345  50.812  1.00 28.07           C  
ATOM    668  C   LYS A  95      28.089  25.129  51.461  1.00 27.56           C  
ATOM    669  O   LYS A  95      28.448  24.746  52.570  1.00 28.81           O  
ATOM    670  CB  LYS A  95      27.807  27.551  50.870  1.00 32.03           C  
ATOM    671  CG  LYS A  95      27.060  27.739  52.178  1.00 36.58           C  
ATOM    672  CD  LYS A  95      27.663  28.837  53.039  1.00 41.57           C  
ATOM    673  CE  LYS A  95      26.567  29.567  53.792  1.00 42.03           C  
ATOM    674  NZ  LYS A  95      27.160  30.622  54.642  1.00 45.57           N  
ATOM    675  N   MET A  96      27.129  24.536  50.762  1.00 28.75           N  
ATOM    676  CA  MET A  96      26.470  23.319  51.211  1.00 29.12           C  
ATOM    677  C   MET A  96      25.659  22.703  50.080  1.00 27.07           C  
ATOM    678  O   MET A  96      25.270  23.395  49.146  1.00 24.53           O  
ATOM    679  CB  MET A  96      25.557  23.629  52.368  1.00 33.10           C  
ATOM    680  CG  MET A  96      24.656  24.817  52.109  1.00 35.67           C  
ATOM    681  SD  MET A  96      23.765  25.124  53.623  1.00 45.37           S  
ATOM    682  CE  MET A  96      22.473  23.908  53.451  1.00 43.37           C  
ATOM    683  N   ALA A  97      25.392  21.404  50.199  1.00 25.77           N  
ATOM    684  CA  ALA A  97      24.821  20.617  49.107  1.00 24.35           C  
ATOM    685  C   ALA A  97      23.550  21.234  48.523  1.00 24.55           C  
ATOM    686  O   ALA A  97      23.448  21.429  47.321  1.00 20.96           O  
ATOM    687  CB  ALA A  97      24.547  19.204  49.577  1.00 25.04           C  
ATOM    688  N   GLU A  98      22.600  21.576  49.388  1.00 24.20           N  
ATOM    689  CA  GLU A  98      21.311  22.077  48.948  1.00 25.24           C  
ATOM    690  C   GLU A  98      21.367  23.428  48.234  1.00 24.51           C  
ATOM    691  O   GLU A  98      20.406  23.793  47.576  1.00 24.81           O  
ATOM    692  CB  GLU A  98      20.364  22.186  50.139  1.00 26.56           C  
ATOM    693  CG  GLU A  98      20.016  20.864  50.794  1.00 26.72           C  
ATOM    694  CD  GLU A  98      19.521  21.064  52.216  1.00 28.10           C  
ATOM    695  OE1 GLU A  98      18.346  21.432  52.404  1.00 28.46           O  
ATOM    696  OE2 GLU A  98      20.317  20.864  53.147  1.00 30.14           O  
ATOM    697  N   SER A  99      22.472  24.167  48.355  1.00 24.61           N  
ATOM    698  CA  SER A  99      22.602  25.435  47.643  1.00 25.82           C  
ATOM    699  C   SER A  99      23.495  25.325  46.407  1.00 25.76           C  
ATOM    700  O   SER A  99      23.789  26.327  45.763  1.00 26.10           O  
ATOM    701  CB  SER A  99      23.045  26.566  48.586  1.00 26.84           C  
ATOM    702  OG  SER A  99      24.263  26.285  49.225  1.00 31.29           O  
ATOM    703  N   GLY A 100      23.912  24.110  46.062  1.00 24.10           N  
ATOM    704  CA  GLY A 100      24.565  23.870  44.772  1.00 23.86           C  
ATOM    705  C   GLY A 100      26.079  23.901  44.840  1.00 22.58           C  
ATOM    706  O   GLY A 100      26.677  23.930  45.927  1.00 21.69           O  
ATOM    707  N   TYR A 101      26.709  23.877  43.665  1.00 23.08           N  
ATOM    708  CA  TYR A 101      28.171  23.816  43.569  1.00 23.04           C  
ATOM    709  C   TYR A 101      28.761  22.651  44.357  1.00 20.30           C  
ATOM    710  O   TYR A 101      29.896  22.727  44.826  1.00 19.46           O  
ATOM    711  CB  TYR A 101      28.785  25.142  44.040  1.00 26.01           C  
ATOM    712  CG  TYR A 101      28.410  26.285  43.139  1.00 28.82           C  
ATOM    713  CD1 TYR A 101      29.064  26.467  41.931  1.00 32.21           C  
ATOM    714  CD2 TYR A 101      27.381  27.160  43.470  1.00 31.97           C  
ATOM    715  CE1 TYR A 101      28.724  27.503  41.084  1.00 33.31           C  
ATOM    716  CE2 TYR A 101      27.027  28.198  42.625  1.00 34.71           C  
ATOM    717  CZ  TYR A 101      27.705  28.360  41.430  1.00 35.04           C  
ATOM    718  OH  TYR A 101      27.376  29.388  40.569  1.00 37.46           O  
ATOM    719  N   ASP A 102      28.002  21.564  44.462  1.00 19.25           N  
ATOM    720  CA  ASP A 102      28.388  20.434  45.296  1.00 19.04           C  
ATOM    721  C   ASP A 102      29.270  19.516  44.455  1.00 18.99           C  
ATOM    722  O   ASP A 102      28.826  18.496  43.955  1.00 18.91           O  
ATOM    723  CB  ASP A 102      27.157  19.687  45.798  1.00 18.54           C  
ATOM    724  CG  ASP A 102      27.489  18.681  46.909  1.00 18.32           C  
ATOM    725  OD1 ASP A 102      28.653  18.640  47.366  1.00 17.33           O  
ATOM    726  OD2 ASP A 102      26.563  17.944  47.337  1.00 19.46           O  
ATOM    727  N   ILE A 103      30.520  19.921  44.300  1.00 19.36           N  
ATOM    728  CA  ILE A 103      31.433  19.256  43.390  1.00 19.51           C  
ATOM    729  C   ILE A 103      32.854  19.436  43.885  1.00 19.36           C  
ATOM    730  O   ILE A 103      33.258  20.514  44.359  1.00 19.76           O  
ATOM    731  CB  ILE A 103      31.229  19.762  41.940  1.00 19.30           C  
ATOM    732  CG1 ILE A 103      31.974  18.884  40.937  1.00 19.35           C  
ATOM    733  CG2 ILE A 103      31.616  21.222  41.785  1.00 20.52           C  
ATOM    734  CD1 ILE A 103      31.617  19.194  39.496  1.00 19.26           C  
ATOM    735  N   ALA A 104      33.607  18.352  43.811  1.00 19.28           N  
ATOM    736  CA  ALA A 104      34.983  18.370  44.218  1.00 19.38           C  
ATOM    737  C   ALA A 104      35.809  17.392  43.387  1.00 19.25           C  
ATOM    738  O   ALA A 104      35.298  16.391  42.860  1.00 18.92           O  
ATOM    739  CB  ALA A 104      35.084  18.041  45.707  1.00 20.06           C  
ATOM    740  N   LEU A 105      37.091  17.697  43.268  1.00 19.78           N  
ATOM    741  CA  LEU A 105      38.023  16.815  42.611  1.00 20.95           C  
ATOM    742  C   LEU A 105      39.012  16.294  43.639  1.00 20.55           C  
ATOM    743  O   LEU A 105      39.439  17.042  44.542  1.00 21.45           O  
ATOM    744  CB  LEU A 105      38.776  17.574  41.531  1.00 21.30           C  
ATOM    745  CG  LEU A 105      37.994  17.945  40.288  1.00 21.95           C  
ATOM    746  CD1 LEU A 105      38.619  19.168  39.621  1.00 22.17           C  
ATOM    747  CD2 LEU A 105      37.931  16.758  39.341  1.00 21.56           C  
ATOM    748  N   LEU A 106      39.350  15.013  43.524  1.00 19.73           N  
ATOM    749  CA  LEU A 106      40.458  14.444  44.267  1.00 20.14           C  
ATOM    750  C   LEU A 106      41.580  14.183  43.291  1.00 20.02           C  
ATOM    751  O   LEU A 106      41.405  13.452  42.321  1.00 19.57           O  
ATOM    752  CB  LEU A 106      40.081  13.140  44.964  1.00 20.59           C  
ATOM    753  CG  LEU A 106      38.874  13.221  45.896  1.00 21.77           C  
ATOM    754  CD1 LEU A 106      38.623  11.853  46.501  1.00 22.72           C  
ATOM    755  CD2 LEU A 106      39.137  14.274  46.961  1.00 22.98           C  
ATOM    756  N   LYS A 107      42.720  14.803  43.548  1.00 20.42           N  
ATOM    757  CA  LYS A 107      43.930  14.510  42.804  1.00 21.28           C  
ATOM    758  C   LYS A 107      44.665  13.411  43.538  1.00 20.76           C  
ATOM    759  O   LYS A 107      45.063  13.591  44.689  1.00 21.78           O  
ATOM    760  CB  LYS A 107      44.825  15.752  42.692  1.00 23.16           C  
ATOM    761  CG  LYS A 107      45.935  15.594  41.663  1.00 25.13           C  
ATOM    762  CD  LYS A 107      46.866  16.791  41.701  1.00 28.62           C  
ATOM    763  CE  LYS A 107      47.933  16.706  40.627  1.00 30.91           C  
ATOM    764  NZ  LYS A 107      48.717  17.975  40.587  1.00 33.69           N  
ATOM    765  N   LEU A 108      44.844  12.282  42.867  1.00 21.98           N  
ATOM    766  CA  LEU A 108      45.481  11.115  43.432  1.00 23.24           C  
ATOM    767  C   LEU A 108      47.005  11.239  43.461  1.00 24.83           C  
ATOM    768  O   LEU A 108      47.606  11.949  42.656  1.00 25.25           O  
ATOM    769  CB  LEU A 108      45.057   9.860  42.643  1.00 23.75           C  
ATOM    770  CG  LEU A 108      43.544   9.606  42.549  1.00 24.06           C  
ATOM    771  CD1 LEU A 108      43.276   8.322  41.786  1.00 24.47           C  
ATOM    772  CD2 LEU A 108      42.866   9.544  43.918  1.00 24.47           C  
ATOM    773  N   GLU A 109      47.628  10.548  44.407  1.00 26.02           N  
ATOM    774  CA  GLU A 109      49.078  10.566  44.547  1.00 28.34           C  
ATOM    775  C   GLU A 109      49.746   9.788  43.430  1.00 28.25           C  
ATOM    776  O   GLU A 109      50.875  10.078  43.042  1.00 28.55           O  
ATOM    777  CB  GLU A 109      49.500   9.987  45.903  1.00 30.89           C  
ATOM    778  CG  GLU A 109      49.469  11.006  47.026  1.00 33.83           C  
ATOM    779  CD  GLU A 109      49.725  10.403  48.398  1.00 38.33           C  
ATOM    780  OE1 GLU A 109      49.845   9.155  48.509  1.00 38.52           O  
ATOM    781  OE2 GLU A 109      49.800  11.191  49.373  1.00 39.88           O  
ATOM    782  N   THR A 110      49.054   8.774  42.942  1.00 28.87           N  
ATOM    783  CA  THR A 110      49.565   7.933  41.883  1.00 30.71           C  
ATOM    784  C   THR A 110      48.495   7.776  40.822  1.00 31.89           C  
ATOM    785  O   THR A 110      47.333   8.156  41.009  1.00 31.16           O  
ATOM    786  CB  THR A 110      49.995   6.549  42.418  1.00 32.03           C  
ATOM    787  OG1 THR A 110      48.940   5.975  43.197  1.00 31.20           O  
ATOM    788  CG2 THR A 110      51.243   6.682  43.297  1.00 32.99           C  
ATOM    789  N   THR A 111      48.897   7.206  39.703  1.00 30.80           N  
ATOM    790  CA  THR A 111      48.043   7.125  38.535  1.00 32.54           C  
ATOM    791  C   THR A 111      47.289   5.791  38.474  1.00 29.62           C  
ATOM    792  O   THR A 111      47.838   4.741  38.776  1.00 29.16           O  
ATOM    793  CB  THR A 111      48.883   7.429  37.265  1.00 35.44           C  
ATOM    794  OG1 THR A 111      48.535   8.737  36.784  1.00 37.94           O  
ATOM    795  CG2 THR A 111      48.679   6.408  36.162  1.00 37.11           C  
ATOM    796  N   VAL A 112      46.017   5.847  38.095  1.00 28.15           N  
ATOM    797  CA  VAL A 112      45.222   4.637  37.925  1.00 27.65           C  
ATOM    798  C   VAL A 112      45.637   3.964  36.622  1.00 28.81           C  
ATOM    799  O   VAL A 112      45.663   4.604  35.570  1.00 28.83           O  
ATOM    800  CB  VAL A 112      43.713   4.929  37.860  1.00 27.96           C  
ATOM    801  CG1 VAL A 112      42.918   3.654  37.631  1.00 27.88           C  
ATOM    802  CG2 VAL A 112      43.241   5.630  39.128  1.00 29.41           C  
ATOM    803  N   ASN A 113      45.961   2.678  36.696  1.00 28.81           N  
ATOM    804  CA  ASN A 113      46.191   1.877  35.493  1.00 30.20           C  
ATOM    805  C   ASN A 113      44.887   1.254  35.049  1.00 28.19           C  
ATOM    806  O   ASN A 113      44.366   0.361  35.709  1.00 28.82           O  
ATOM    807  CB  ASN A 113      47.222   0.783  35.756  1.00 33.02           C  
ATOM    808  CG  ASN A 113      48.550   1.340  36.216  1.00 36.49           C  
ATOM    809  OD1 ASN A 113      49.114   0.880  37.207  1.00 42.03           O  
ATOM    810  ND2 ASN A 113      49.050   2.349  35.514  1.00 38.89           N  
ATOM    811  N   TYR A 114      44.358   1.740  33.936  1.00 26.80           N  
ATOM    812  CA  TYR A 114      43.040   1.345  33.480  1.00 26.32           C  
ATOM    813  C   TYR A 114      42.984  -0.128  33.085  1.00 26.02           C  
ATOM    814  O   TYR A 114      43.961  -0.697  32.605  1.00 24.53           O  
ATOM    815  CB  TYR A 114      42.595   2.187  32.294  1.00 26.33           C  
ATOM    816  CG  TYR A 114      42.453   3.667  32.568  1.00 27.05           C  
ATOM    817  CD1 TYR A 114      42.073   4.144  33.823  1.00 26.51           C  
ATOM    818  CD2 TYR A 114      42.678   4.593  31.553  1.00 26.95           C  
ATOM    819  CE1 TYR A 114      41.931   5.505  34.054  1.00 27.62           C  
ATOM    820  CE2 TYR A 114      42.543   5.950  31.777  1.00 28.21           C  
ATOM    821  CZ  TYR A 114      42.176   6.400  33.029  1.00 28.10           C  
ATOM    822  OH  TYR A 114      42.032   7.749  33.233  1.00 29.95           O  
ATOM    823  N   ALA A 115      41.820  -0.717  33.300  1.00 25.08           N  
ATOM    824  CA  ALA A 115      41.576  -2.120  32.993  1.00 25.21           C  
ATOM    825  C   ALA A 115      40.075  -2.337  32.987  1.00 26.39           C  
ATOM    826  O   ALA A 115      39.310  -1.407  33.277  1.00 23.66           O  
ATOM    827  CB  ALA A 115      42.241  -3.008  34.030  1.00 24.78           C  
ATOM    828  N   ASP A 116      39.653  -3.558  32.665  1.00 26.86           N  
ATOM    829  CA  ASP A 116      38.230  -3.891  32.617  1.00 29.04           C  
ATOM    830  C   ASP A 116      37.521  -3.608  33.973  1.00 28.29           C  
ATOM    831  O   ASP A 116      36.315  -3.370  33.995  1.00 30.12           O  
ATOM    832  CB  ASP A 116      38.030  -5.360  32.178  1.00 30.85           C  
ATOM    833  CG  ASP A 116      38.369  -5.602  30.675  1.00 34.00           C  
ATOM    834  OD1 ASP A 116      37.727  -4.951  29.822  1.00 33.32           O  
ATOM    835  OD2 ASP A 116      39.261  -6.449  30.342  1.00 31.41           O  
ATOM    836  N   SER A 117      38.274  -3.622  35.080  1.00 25.68           N  
ATOM    837  CA  SER A 117      37.731  -3.352  36.428  1.00 25.70           C  
ATOM    838  C   SER A 117      37.743  -1.865  36.843  1.00 25.24           C  
ATOM    839  O   SER A 117      37.067  -1.473  37.800  1.00 23.69           O  
ATOM    840  CB  SER A 117      38.530  -4.149  37.454  1.00 25.07           C  
ATOM    841  OG  SER A 117      39.881  -3.731  37.449  1.00 26.52           O  
ATOM    842  N   GLN A 118      38.510  -1.041  36.133  1.00 23.61           N  
ATOM    843  CA  GLN A 118      38.669   0.366  36.509  1.00 23.01           C  
ATOM    844  C   GLN A 118      39.054   1.223  35.303  1.00 23.45           C  
ATOM    845  O   GLN A 118      40.140   1.071  34.727  1.00 23.25           O  
ATOM    846  CB  GLN A 118      39.694   0.510  37.642  1.00 22.58           C  
ATOM    847  CG  GLN A 118      41.052  -0.154  37.394  1.00 23.32           C  
ATOM    848  CD  GLN A 118      41.880  -0.296  38.660  1.00 23.47           C  
ATOM    849  OE1 GLN A 118      41.353  -0.649  39.711  1.00 24.14           O  
ATOM    850  NE2 GLN A 118      43.179  -0.046  38.563  1.00 23.75           N  
ATOM    851  N   ARG A 119      38.160   2.134  34.931  1.00 23.68           N  
ATOM    852  CA  ARG A 119      38.400   3.021  33.801  1.00 25.59           C  
ATOM    853  C   ARG A 119      37.530   4.279  33.911  1.00 24.12           C  
ATOM    854  O   ARG A 119      36.564   4.306  34.681  1.00 24.48           O  
ATOM    855  CB  ARG A 119      38.178   2.267  32.480  1.00 27.36           C  
ATOM    856  CG  ARG A 119      36.781   1.711  32.262  1.00 29.09           C  
ATOM    857  CD  ARG A 119      35.895   2.703  31.531  1.00 31.78           C  
ATOM    858  NE  ARG A 119      34.747   2.081  30.863  1.00 33.96           N  
ATOM    859  CZ  ARG A 119      33.710   2.755  30.361  1.00 35.88           C  
ATOM    860  NH1 ARG A 119      33.653   4.080  30.441  1.00 37.37           N  
ATOM    861  NH2 ARG A 119      32.716   2.101  29.769  1.00 39.40           N  
ATOM    862  N   PRO A 121      37.879   5.328  33.165  1.00 23.15           N  
ATOM    863  CA  PRO A 121      37.176   6.583  33.376  1.00 22.97           C  
ATOM    864  C   PRO A 121      35.836   6.625  32.685  1.00 23.22           C  
ATOM    865  O   PRO A 121      35.629   5.939  31.690  1.00 23.68           O  
ATOM    866  CB  PRO A 121      38.141   7.628  32.793  1.00 23.13           C  
ATOM    867  CG  PRO A 121      38.915   6.893  31.755  1.00 23.38           C  
ATOM    868  CD  PRO A 121      38.892   5.430  32.093  1.00 23.79           C  
ATOM    869  N   ILE A 122      34.915   7.412  33.234  1.00 22.58           N  
ATOM    870  CA  ILE A 122      33.654   7.691  32.565  1.00 22.76           C  
ATOM    871  C   ILE A 122      33.753   9.023  31.815  1.00 23.28           C  
ATOM    872  O   ILE A 122      34.378   9.972  32.289  1.00 22.83           O  
ATOM    873  CB  ILE A 122      32.455   7.678  33.548  1.00 23.22           C  
ATOM    874  CG1 ILE A 122      31.160   7.959  32.791  1.00 22.40           C  
ATOM    875  CG2 ILE A 122      32.640   8.683  34.686  1.00 22.86           C  
ATOM    876  CD1 ILE A 122      29.935   7.481  33.517  1.00 21.71           C  
ATOM    877  N   SER A 123      33.149   9.073  30.631  1.00 24.57           N  
ATOM    878  CA  SER A 123      33.133  10.272  29.811  1.00 26.79           C  
ATOM    879  C   SER A 123      32.276  11.365  30.441  1.00 25.91           C  
ATOM    880  O   SER A 123      31.154  11.115  30.851  1.00 24.13           O  
ATOM    881  CB  SER A 123      32.572   9.960  28.409  1.00 29.07           C  
ATOM    882  OG  SER A 123      33.496   9.190  27.650  1.00 31.84           O  
ATOM    883  N   LEU A 124      32.807  12.578  30.485  1.00 26.59           N  
ATOM    884  CA  LEU A 124      32.020  13.734  30.916  1.00 26.76           C  
ATOM    885  C   LEU A 124      30.995  14.045  29.822  1.00 27.27           C  
ATOM    886  O   LEU A 124      31.232  13.753  28.650  1.00 26.69           O  
ATOM    887  CB  LEU A 124      32.919  14.941  31.196  1.00 26.99           C  
ATOM    888  CG  LEU A 124      33.884  14.804  32.385  1.00 29.07           C  
ATOM    889  CD1 LEU A 124      34.898  15.935  32.387  1.00 29.81           C  
ATOM    890  CD2 LEU A 124      33.140  14.752  33.714  1.00 29.39           C  
ATOM    891  N   PRO A 125      29.849  14.631  30.197  1.00 27.23           N  
ATOM    892  CA  PRO A 125      28.867  14.975  29.177  1.00 28.38           C  
ATOM    893  C   PRO A 125      29.360  16.131  28.321  1.00 28.64           C  
ATOM    894  O   PRO A 125      30.160  16.951  28.764  1.00 26.55           O  
ATOM    895  CB  PRO A 125      27.620  15.370  29.990  1.00 29.34           C  
ATOM    896  CG  PRO A 125      28.129  15.755  31.337  1.00 28.47           C  
ATOM    897  CD  PRO A 125      29.508  15.179  31.521  1.00 28.38           C  
ATOM    898  N   SER A 126      28.899  16.167  27.083  1.00 30.81           N  
ATOM    899  CA  SER A 126      29.228  17.245  26.180  1.00 31.82           C  
ATOM    900  C   SER A 126      28.185  18.360  26.314  1.00 30.90           C  
ATOM    901  O   SER A 126      27.000  18.099  26.528  1.00 29.67           O  
ATOM    902  CB  SER A 126      29.280  16.715  24.742  1.00 33.95           C  
ATOM    903  OG  SER A 126      29.110  17.773  23.815  1.00 36.71           O  
ATOM    904  N   LYS A 127      28.627  19.604  26.176  1.00 30.89           N  
ATOM    905  CA  LYS A 127      27.703  20.734  26.186  1.00 33.05           C  
ATOM    906  C   LYS A 127      26.639  20.585  25.090  1.00 35.03           C  
ATOM    907  O   LYS A 127      25.536  21.107  25.219  1.00 37.17           O  
ATOM    908  CB  LYS A 127      28.448  22.052  26.015  1.00 32.76           C  
ATOM    909  CG  LYS A 127      29.369  22.401  27.168  1.00 32.77           C  
ATOM    910  CD  LYS A 127      29.904  23.806  27.010  1.00 32.09           C  
ATOM    911  CE  LYS A 127      30.864  24.180  28.115  1.00 31.51           C  
ATOM    912  NZ  LYS A 127      31.553  25.458  27.809  1.00 31.71           N  
ATOM    913  N   GLY A 128      26.975  19.860  24.027  1.00 35.57           N  
ATOM    914  CA  GLY A 128      26.048  19.600  22.932  1.00 38.14           C  
ATOM    915  C   GLY A 128      25.004  18.530  23.199  1.00 39.53           C  
ATOM    916  O   GLY A 128      24.124  18.311  22.368  1.00 42.72           O  
ATOM    917  N   ASP A 129      25.092  17.861  24.348  1.00 38.99           N  
ATOM    918  CA  ASP A 129      24.114  16.839  24.726  1.00 38.35           C  
ATOM    919  C   ASP A 129      23.123  17.330  25.791  1.00 41.54           C  
ATOM    920  O   ASP A 129      22.385  16.533  26.372  1.00 43.11           O  
ATOM    921  CB  ASP A 129      24.844  15.577  25.193  1.00 33.99           C  
ATOM    922  CG  ASP A 129      25.400  14.760  24.034  1.00 32.28           C  
ATOM    923  OD1 ASP A 129      25.201  15.139  22.855  1.00 32.37           O  
ATOM    924  OD2 ASP A 129      26.038  13.717  24.279  1.00 32.13           O  
ATOM    925  N   ARG A 130      23.087  18.642  26.025  1.00 45.13           N  
ATOM    926  CA  ARG A 130      22.094  19.243  26.933  1.00 47.83           C  
ATOM    927  C   ARG A 130      20.662  19.056  26.430  1.00 50.59           C  
ATOM    928  O   ARG A 130      19.710  19.061  27.209  1.00 50.23           O  
ATOM    929  CB  ARG A 130      22.376  20.728  27.108  1.00 48.09           C  
ATOM    930  CG  ARG A 130      23.600  21.003  27.948  1.00 49.72           C  
ATOM    931  CD  ARG A 130      24.096  22.412  27.722  1.00 50.23           C  
ATOM    932  NE  ARG A 130      24.702  22.973  28.920  1.00 49.14           N  
ATOM    933  CZ  ARG A 130      25.617  23.936  28.914  1.00 49.57           C  
ATOM    934  NH1 ARG A 130      26.055  24.452  27.767  1.00 49.51           N  
ATOM    935  NH2 ARG A 130      26.103  24.384  30.060  1.00 50.22           N  
ATOM    936  N   ASN A 131      20.527  18.939  25.114  1.00 55.24           N  
ATOM    937  CA  ASN A 131      19.254  18.594  24.465  1.00 57.46           C  
ATOM    938  C   ASN A 131      18.871  17.108  24.493  1.00 57.30           C  
ATOM    939  O   ASN A 131      17.691  16.773  24.365  1.00 56.54           O  
ATOM    940  CB  ASN A 131      19.202  19.148  23.022  1.00 58.45           C  
ATOM    941  CG  ASN A 131      20.181  18.470  22.048  1.00 60.91           C  
ATOM    942  OD1 ASN A 131      19.912  18.452  20.843  1.00 59.91           O  
ATOM    943  ND2 ASN A 131      21.318  17.946  22.534  1.00 60.35           N  
ATOM    944  N   VAL A 132      19.850  16.223  24.673  1.00 55.81           N  
ATOM    945  CA  VAL A 132      19.584  14.789  24.701  1.00 54.09           C  
ATOM    946  C   VAL A 132      18.617  14.461  25.832  1.00 54.39           C  
ATOM    947  O   VAL A 132      18.747  14.988  26.939  1.00 55.89           O  
ATOM    948  CB  VAL A 132      20.884  13.968  24.864  1.00 53.46           C  
ATOM    949  CG1 VAL A 132      20.594  12.551  25.342  1.00 52.84           C  
ATOM    950  CG2 VAL A 132      21.655  13.938  23.550  1.00 53.77           C  
ATOM    951  N   ILE A 132A     17.642  13.605  25.529  1.00 54.73           N  
ATOM    952  CA  ILE A 132A     16.712  13.084  26.521  1.00 54.49           C  
ATOM    953  C   ILE A 132A     17.231  11.711  26.947  1.00 51.39           C  
ATOM    954  O   ILE A 132A     17.051  10.718  26.235  1.00 52.02           O  
ATOM    955  CB  ILE A 132A     15.279  12.953  25.951  1.00 56.69           C  
ATOM    956  CG1 ILE A 132A     14.764  14.308  25.428  1.00 59.77           C  
ATOM    957  CG2 ILE A 132A     14.330  12.383  27.001  1.00 56.89           C  
ATOM    958  CD1 ILE A 132A     14.268  15.268  26.499  1.00 59.28           C  
ATOM    959  N   TYR A 133      17.895  11.662  28.099  1.00 47.73           N  
ATOM    960  CA  TYR A 133      18.443  10.413  28.603  1.00 43.81           C  
ATOM    961  C   TYR A 133      17.325   9.568  29.201  1.00 42.57           C  
ATOM    962  O   TYR A 133      16.597  10.026  30.087  1.00 43.26           O  
ATOM    963  CB  TYR A 133      19.489  10.672  29.682  1.00 44.02           C  
ATOM    964  CG  TYR A 133      20.734  11.397  29.246  1.00 43.36           C  
ATOM    965  CD1 TYR A 133      21.763  10.723  28.598  1.00 43.34           C  
ATOM    966  CD2 TYR A 133      20.914  12.744  29.537  1.00 43.18           C  
ATOM    967  CE1 TYR A 133      22.919  11.376  28.227  1.00 42.79           C  
ATOM    968  CE2 TYR A 133      22.066  13.407  29.168  1.00 43.06           C  
ATOM    969  CZ  TYR A 133      23.064  12.720  28.515  1.00 44.35           C  
ATOM    970  OH  TYR A 133      24.206  13.384  28.153  1.00 48.45           O  
ATOM    971  N   THR A 134      17.198   8.333  28.726  1.00 40.02           N  
ATOM    972  CA  THR A 134      16.142   7.428  29.179  1.00 40.25           C  
ATOM    973  C   THR A 134      16.692   6.155  29.797  1.00 37.17           C  
ATOM    974  O   THR A 134      15.944   5.210  30.028  1.00 37.22           O  
ATOM    975  CB  THR A 134      15.232   7.016  28.003  1.00 41.62           C  
ATOM    976  OG1 THR A 134      16.009   6.297  27.039  1.00 42.59           O  
ATOM    977  CG2 THR A 134      14.610   8.231  27.347  1.00 43.67           C  
ATOM    978  N   ASP A 135      17.998   6.132  30.058  1.00 37.13           N  
ATOM    979  CA  ASP A 135      18.676   4.943  30.577  1.00 35.78           C  
ATOM    980  C   ASP A 135      19.728   5.375  31.613  1.00 33.20           C  
ATOM    981  O   ASP A 135      20.933   5.199  31.426  1.00 32.55           O  
ATOM    982  CB  ASP A 135      19.309   4.161  29.420  1.00 37.64           C  
ATOM    983  CG  ASP A 135      19.724   2.754  29.814  1.00 38.83           C  
ATOM    984  OD1 ASP A 135      19.259   2.240  30.854  1.00 40.45           O  
ATOM    985  OD2 ASP A 135      20.523   2.152  29.072  1.00 41.64           O  
ATOM    986  N   CYS A 136      19.243   5.966  32.699  1.00 30.84           N  
ATOM    987  CA  CYS A 136      20.105   6.548  33.720  1.00 29.69           C  
ATOM    988  C   CYS A 136      20.074   5.686  34.968  1.00 26.90           C  
ATOM    989  O   CYS A 136      19.011   5.202  35.355  1.00 26.22           O  
ATOM    990  CB  CYS A 136      19.668   7.981  34.036  1.00 29.66           C  
ATOM    991  SG  CYS A 136      19.862   9.134  32.658  1.00 31.68           S  
ATOM    992  N   TRP A 137      21.253   5.488  35.571  1.00 25.62           N  
ATOM    993  CA  TRP A 137      21.422   4.633  36.747  1.00 23.96           C  
ATOM    994  C   TRP A 137      22.184   5.361  37.862  1.00 23.28           C  
ATOM    995  O   TRP A 137      23.145   6.091  37.601  1.00 23.57           O  
ATOM    996  CB  TRP A 137      22.169   3.346  36.375  1.00 25.00           C  
ATOM    997  CG  TRP A 137      21.400   2.452  35.421  1.00 25.55           C  
ATOM    998  CD1 TRP A 137      21.206   2.652  34.084  1.00 26.31           C  
ATOM    999  CD2 TRP A 137      20.726   1.234  35.746  1.00 25.83           C  
ATOM   1000  NE1 TRP A 137      20.451   1.629  33.557  1.00 26.90           N  
ATOM   1001  CE2 TRP A 137      20.142   0.748  34.556  1.00 27.08           C  
ATOM   1002  CE3 TRP A 137      20.559   0.508  36.920  1.00 26.60           C  
ATOM   1003  CZ2 TRP A 137      19.409  -0.431  34.514  1.00 27.53           C  
ATOM   1004  CZ3 TRP A 137      19.831  -0.658  36.883  1.00 28.05           C  
ATOM   1005  CH2 TRP A 137      19.267  -1.120  35.684  1.00 28.81           C  
ATOM   1006  N   VAL A 138      21.724   5.184  39.099  1.00 21.99           N  
ATOM   1007  CA  VAL A 138      22.483   5.623  40.277  1.00 22.20           C  
ATOM   1008  C   VAL A 138      23.003   4.385  41.005  1.00 21.05           C  
ATOM   1009  O   VAL A 138      22.301   3.380  41.130  1.00 21.50           O  
ATOM   1010  CB  VAL A 138      21.653   6.527  41.230  1.00 22.43           C  
ATOM   1011  CG1 VAL A 138      20.456   5.786  41.799  1.00 22.71           C  
ATOM   1012  CG2 VAL A 138      22.522   7.064  42.366  1.00 22.38           C  
ATOM   1013  N   THR A 139      24.232   4.473  41.504  1.00 20.23           N  
ATOM   1014  CA  THR A 139      24.921   3.333  42.097  1.00 19.13           C  
ATOM   1015  C   THR A 139      25.617   3.731  43.393  1.00 18.39           C  
ATOM   1016  O   THR A 139      25.964   4.898  43.569  1.00 18.05           O  
ATOM   1017  CB  THR A 139      25.992   2.789  41.131  1.00 20.03           C  
ATOM   1018  OG1 THR A 139      26.814   3.867  40.637  1.00 20.09           O  
ATOM   1019  CG2 THR A 139      25.339   2.088  39.963  1.00 21.18           C  
ATOM   1020  N   GLY A 140      25.805   2.770  44.294  1.00 17.32           N  
ATOM   1021  CA  GLY A 140      26.561   3.016  45.506  1.00 17.70           C  
ATOM   1022  C   GLY A 140      26.391   1.968  46.579  1.00 18.76           C  
ATOM   1023  O   GLY A 140      25.604   1.007  46.418  1.00 20.43           O  
ATOM   1024  N   TRP A 141      27.138   2.159  47.662  1.00 18.42           N  
ATOM   1025  CA  TRP A 141      27.129   1.265  48.817  1.00 19.14           C  
ATOM   1026  C   TRP A 141      26.268   1.825  49.962  1.00 19.78           C  
ATOM   1027  O   TRP A 141      26.394   1.397  51.112  1.00 20.99           O  
ATOM   1028  CB  TRP A 141      28.558   1.018  49.299  1.00 19.59           C  
ATOM   1029  CG  TRP A 141      29.390   0.169  48.372  1.00 19.24           C  
ATOM   1030  CD1 TRP A 141      29.470  -1.184  48.369  1.00 19.52           C  
ATOM   1031  CD2 TRP A 141      30.280   0.625  47.337  1.00 19.16           C  
ATOM   1032  NE1 TRP A 141      30.343  -1.613  47.397  1.00 19.25           N  
ATOM   1033  CE2 TRP A 141      30.859  -0.521  46.750  1.00 19.13           C  
ATOM   1034  CE3 TRP A 141      30.653   1.886  46.866  1.00 18.58           C  
ATOM   1035  CZ2 TRP A 141      31.772  -0.448  45.696  1.00 19.14           C  
ATOM   1036  CZ3 TRP A 141      31.569   1.962  45.821  1.00 18.99           C  
ATOM   1037  CH2 TRP A 141      32.124   0.790  45.250  1.00 18.67           C  
ATOM   1038  N   GLY A 142      25.370   2.747  49.630  1.00 20.91           N  
ATOM   1039  CA  GLY A 142      24.601   3.470  50.640  1.00 22.02           C  
ATOM   1040  C   GLY A 142      23.470   2.644  51.224  1.00 23.70           C  
ATOM   1041  O   GLY A 142      23.225   1.514  50.819  1.00 22.87           O  
ATOM   1042  N   TYR A 143      22.777   3.241  52.186  1.00 26.51           N  
ATOM   1043  CA  TYR A 143      21.644   2.615  52.866  1.00 26.58           C  
ATOM   1044  C   TYR A 143      20.568   2.126  51.894  1.00 26.94           C  
ATOM   1045  O   TYR A 143      20.355   2.722  50.831  1.00 24.96           O  
ATOM   1046  CB  TYR A 143      20.968   3.635  53.781  1.00 27.83           C  
ATOM   1047  CG  TYR A 143      21.733   4.134  54.989  1.00 26.96           C  
ATOM   1048  CD1 TYR A 143      23.103   3.885  55.174  1.00 26.49           C  
ATOM   1049  CD2 TYR A 143      21.071   4.895  55.944  1.00 27.19           C  
ATOM   1050  CE1 TYR A 143      23.770   4.372  56.284  1.00 26.33           C  
ATOM   1051  CE2 TYR A 143      21.727   5.393  57.056  1.00 27.55           C  
ATOM   1052  CZ  TYR A 143      23.067   5.135  57.223  1.00 27.05           C  
ATOM   1053  OH  TYR A 143      23.693   5.652  58.328  1.00 26.76           O  
ATOM   1054  N   ARG A 144      19.879   1.062  52.292  1.00 29.02           N  
ATOM   1055  CA  ARG A 144      18.661   0.599  51.618  1.00 34.37           C  
ATOM   1056  C   ARG A 144      17.393   1.279  52.130  1.00 36.00           C  
ATOM   1057  O   ARG A 144      16.343   1.175  51.498  1.00 32.49           O  
ATOM   1058  CB  ARG A 144      18.484  -0.896  51.821  1.00 38.54           C  
ATOM   1059  CG  ARG A 144      19.375  -1.746  50.959  1.00 42.75           C  
ATOM   1060  CD  ARG A 144      19.330  -3.195  51.417  1.00 48.08           C  
ATOM   1061  NE  ARG A 144      20.487  -3.911  50.889  1.00 54.80           N  
ATOM   1062  CZ  ARG A 144      20.508  -4.665  49.789  1.00 57.71           C  
ATOM   1063  NH1 ARG A 144      19.413  -4.866  49.056  1.00 57.54           N  
ATOM   1064  NH2 ARG A 144      21.656  -5.240  49.430  1.00 59.96           N  
ATOM   1065  N   LYS A 145      17.484   1.941  53.278  1.00 38.69           N  
ATOM   1066  CA  LYS A 145      16.381   2.752  53.807  1.00 42.82           C  
ATOM   1067  C   LYS A 145      16.969   3.869  54.676  1.00 42.09           C  
ATOM   1068  O   LYS A 145      18.109   3.761  55.124  1.00 40.81           O  
ATOM   1069  CB  LYS A 145      15.394   1.875  54.602  1.00 43.94           C  
ATOM   1070  CG  LYS A 145      16.003   1.200  55.820  1.00 46.53           C  
ATOM   1071  CD  LYS A 145      15.116   0.126  56.432  1.00 48.67           C  
ATOM   1072  CE  LYS A 145      15.840  -0.579  57.575  1.00 51.29           C  
ATOM   1073  NZ  LYS A 145      15.111  -1.755  58.130  1.00 51.72           N  
ATOM   1074  N   LEU A 146      16.196   4.929  54.921  1.00 44.50           N  
ATOM   1075  CA  LEU A 146      16.715   6.135  55.601  1.00 45.64           C  
ATOM   1076  C   LEU A 146      17.527   5.801  56.853  1.00 45.83           C  
ATOM   1077  O   LEU A 146      18.589   6.382  57.080  1.00 45.56           O  
ATOM   1078  CB  LEU A 146      15.588   7.110  55.978  1.00 46.98           C  
ATOM   1079  CG  LEU A 146      15.891   8.617  55.941  1.00 49.04           C  
ATOM   1080  CD1 LEU A 146      14.938   9.352  56.875  1.00 50.75           C  
ATOM   1081  CD2 LEU A 146      17.328   8.995  56.284  1.00 48.78           C  
ATOM   1082  N   ARG A 147      17.027   4.868  57.657  1.00 45.23           N  
ATOM   1083  CA  ARG A 147      17.759   4.404  58.828  1.00 47.21           C  
ATOM   1084  C   ARG A 147      18.205   2.975  58.543  1.00 45.19           C  
ATOM   1085  O   ARG A 147      17.397   2.049  58.568  1.00 46.03           O  
ATOM   1086  CB  ARG A 147      16.892   4.493  60.100  1.00 51.77           C  
ATOM   1087  CG  ARG A 147      16.067   5.780  60.244  1.00 54.72           C  
ATOM   1088  CD  ARG A 147      16.927   7.036  60.378  1.00 58.42           C  
ATOM   1089  NE  ARG A 147      16.148   8.283  60.290  1.00 61.16           N  
ATOM   1090  CZ  ARG A 147      16.668   9.515  60.291  1.00 62.90           C  
ATOM   1091  NH1 ARG A 147      17.985   9.701  60.383  1.00 63.30           N  
ATOM   1092  NH2 ARG A 147      15.866  10.575  60.204  1.00 62.71           N  
ATOM   1093  N   ASP A 148      19.490   2.811  58.234  1.00 42.94           N  
ATOM   1094  CA  ASP A 148      20.041   1.525  57.802  1.00 41.66           C  
ATOM   1095  C   ASP A 148      21.552   1.569  58.007  1.00 40.62           C  
ATOM   1096  O   ASP A 148      22.016   2.175  58.969  1.00 41.90           O  
ATOM   1097  CB  ASP A 148      19.684   1.271  56.327  1.00 41.97           C  
ATOM   1098  CG  ASP A 148      19.825  -0.191  55.914  1.00 41.60           C  
ATOM   1099  OD1 ASP A 148      19.439  -1.078  56.698  1.00 40.67           O  
ATOM   1100  OD2 ASP A 148      20.315  -0.449  54.791  1.00 39.61           O  
ATOM   1101  N   LYS A 149      22.317   0.949  57.108  1.00 37.82           N  
ATOM   1102  CA  LYS A 149      23.769   0.905  57.216  1.00 36.26           C  
ATOM   1103  C   LYS A 149      24.403   0.728  55.833  1.00 31.59           C  
ATOM   1104  O   LYS A 149      23.711   0.422  54.853  1.00 27.09           O  
ATOM   1105  CB  LYS A 149      24.191  -0.246  58.125  1.00 38.90           C  
ATOM   1106  CG  LYS A 149      24.166  -1.609  57.441  1.00 41.54           C  
ATOM   1107  CD  LYS A 149      24.476  -2.740  58.405  1.00 44.68           C  
ATOM   1108  CE  LYS A 149      23.243  -3.140  59.199  1.00 46.09           C  
ATOM   1109  NZ  LYS A 149      23.535  -4.240  60.164  1.00 47.77           N  
ATOM   1110  N   ILE A 151      25.721   0.911  55.774  1.00 29.44           N  
ATOM   1111  CA  ILE A 151      26.486   0.748  54.524  1.00 27.21           C  
ATOM   1112  C   ILE A 151      26.419  -0.704  54.069  1.00 27.85           C  
ATOM   1113  O   ILE A 151      26.616  -1.614  54.860  1.00 28.49           O  
ATOM   1114  CB  ILE A 151      27.965   1.164  54.716  1.00 26.51           C  
ATOM   1115  CG1 ILE A 151      28.066   2.663  55.029  1.00 25.85           C  
ATOM   1116  CG2 ILE A 151      28.818   0.787  53.504  1.00 25.96           C  
ATOM   1117  CD1 ILE A 151      27.243   3.560  54.129  1.00 26.23           C  
ATOM   1118  N   GLN A 152      26.132  -0.906  52.790  1.00 25.59           N  
ATOM   1119  CA  GLN A 152      25.948  -2.239  52.229  1.00 26.19           C  
ATOM   1120  C   GLN A 152      27.264  -2.806  51.715  1.00 25.58           C  
ATOM   1121  O   GLN A 152      28.112  -2.075  51.254  1.00 25.07           O  
ATOM   1122  CB  GLN A 152      24.934  -2.168  51.091  1.00 27.03           C  
ATOM   1123  CG  GLN A 152      23.590  -1.643  51.553  1.00 28.59           C  
ATOM   1124  CD  GLN A 152      22.989  -2.547  52.604  1.00 29.56           C  
ATOM   1125  OE1 GLN A 152      22.840  -3.735  52.370  1.00 30.02           O  
ATOM   1126  NE2 GLN A 152      22.652  -1.998  53.762  1.00 32.08           N  
ATOM   1127  N   ASN A 153      27.427  -4.117  51.816  1.00 24.67           N  
ATOM   1128  CA  ASN A 153      28.597  -4.788  51.275  1.00 24.19           C  
ATOM   1129  C   ASN A 153      28.712  -4.654  49.750  1.00 23.82           C  
ATOM   1130  O   ASN A 153      29.727  -4.174  49.238  1.00 22.99           O  
ATOM   1131  CB  ASN A 153      28.568  -6.262  51.676  1.00 25.21           C  
ATOM   1132  CG  ASN A 153      29.830  -6.998  51.301  1.00 25.80           C  
ATOM   1133  OD1 ASN A 153      30.925  -6.436  51.330  1.00 26.78           O  
ATOM   1134  ND2 ASN A 153      29.688  -8.286  50.971  1.00 26.00           N  
ATOM   1135  N   THR A 154      27.666  -5.055  49.033  1.00 23.80           N  
ATOM   1136  CA  THR A 154      27.705  -5.116  47.558  1.00 23.56           C  
ATOM   1137  C   THR A 154      27.183  -3.859  46.869  1.00 22.65           C  
ATOM   1138  O   THR A 154      26.093  -3.373  47.196  1.00 22.15           O  
ATOM   1139  CB  THR A 154      26.896  -6.317  47.060  1.00 24.98           C  
ATOM   1140  OG1 THR A 154      27.312  -7.479  47.781  1.00 24.62           O  
ATOM   1141  CG2 THR A 154      27.112  -6.534  45.592  1.00 25.09           C  
ATOM   1142  N   LEU A 155      27.951  -3.349  45.905  1.00 20.98           N  
ATOM   1143  CA  LEU A 155      27.544  -2.179  45.121  1.00 20.72           C  
ATOM   1144  C   LEU A 155      26.162  -2.378  44.499  1.00 21.28           C  
ATOM   1145  O   LEU A 155      25.935  -3.337  43.761  1.00 22.06           O  
ATOM   1146  CB  LEU A 155      28.575  -1.888  44.022  1.00 20.33           C  
ATOM   1147  CG  LEU A 155      28.337  -0.652  43.167  1.00 20.77           C  
ATOM   1148  CD1 LEU A 155      28.549   0.638  43.952  1.00 20.54           C  
ATOM   1149  CD2 LEU A 155      29.235  -0.682  41.935  1.00 21.48           C  
ATOM   1150  N   GLN A 156      25.241  -1.471  44.824  1.00 21.56           N  
ATOM   1151  CA  GLN A 156      23.878  -1.535  44.354  1.00 22.06           C  
ATOM   1152  C   GLN A 156      23.677  -0.594  43.182  1.00 22.58           C  
ATOM   1153  O   GLN A 156      24.420   0.393  42.999  1.00 21.33           O  
ATOM   1154  CB  GLN A 156      22.896  -1.178  45.470  1.00 23.45           C  
ATOM   1155  CG  GLN A 156      22.963  -2.077  46.696  1.00 24.95           C  
ATOM   1156  CD  GLN A 156      22.325  -3.428  46.463  1.00 26.67           C  
ATOM   1157  OE1 GLN A 156      21.151  -3.509  46.102  1.00 29.74           O  
ATOM   1158  NE2 GLN A 156      23.087  -4.495  46.674  1.00 28.02           N  
ATOM   1159  N   LYS A 157      22.660  -0.906  42.385  1.00 22.27           N  
ATOM   1160  CA  LYS A 157      22.298  -0.094  41.230  1.00 22.21           C  
ATOM   1161  C   LYS A 157      20.785   0.056  41.163  1.00 22.70           C  
ATOM   1162  O   LYS A 157      20.048  -0.853  41.561  1.00 23.23           O  
ATOM   1163  CB  LYS A 157      22.789  -0.766  39.949  1.00 22.75           C  
ATOM   1164  CG  LYS A 157      22.174  -2.136  39.697  1.00 23.73           C  
ATOM   1165  CD  LYS A 157      22.700  -2.720  38.400  1.00 24.21           C  
ATOM   1166  CE  LYS A 157      22.064  -4.063  38.092  1.00 24.33           C  
ATOM   1167  NZ  LYS A 157      22.763  -4.654  36.910  1.00 24.75           N  
ATOM   1168  N   ALA A 158      20.333   1.191  40.654  1.00 21.62           N  
ATOM   1169  CA  ALA A 158      18.913   1.425  40.441  1.00 23.80           C  
ATOM   1170  C   ALA A 158      18.720   2.330  39.247  1.00 24.90           C  
ATOM   1171  O   ALA A 158      19.400   3.355  39.090  1.00 24.33           O  
ATOM   1172  CB  ALA A 158      18.264   2.014  41.690  1.00 23.89           C  
ATOM   1173  N   LYS A 159      17.792   1.925  38.389  1.00 25.58           N  
ATOM   1174  CA  LYS A 159      17.454   2.662  37.205  1.00 27.76           C  
ATOM   1175  C   LYS A 159      16.428   3.701  37.607  1.00 28.52           C  
ATOM   1176  O   LYS A 159      15.424   3.367  38.234  1.00 29.87           O  
ATOM   1177  CB  LYS A 159      16.853   1.719  36.169  1.00 29.64           C  
ATOM   1178  CG  LYS A 159      16.628   2.359  34.816  1.00 31.07           C  
ATOM   1179  CD  LYS A 159      15.901   1.404  33.882  1.00 33.20           C  
ATOM   1180  CE  LYS A 159      15.970   1.893  32.449  1.00 35.43           C  
ATOM   1181  NZ  LYS A 159      15.052   1.109  31.583  1.00 37.51           N  
ATOM   1182  N   ILE A 160      16.683   4.956  37.267  1.00 28.80           N  
ATOM   1183  CA  ILE A 160      15.806   6.046  37.692  1.00 30.35           C  
ATOM   1184  C   ILE A 160      15.657   7.094  36.590  1.00 30.43           C  
ATOM   1185  O   ILE A 160      16.645   7.534  36.007  1.00 29.44           O  
ATOM   1186  CB  ILE A 160      16.327   6.716  38.977  1.00 32.13           C  
ATOM   1187  CG1 ILE A 160      16.467   5.691  40.102  1.00 33.46           C  
ATOM   1188  CG2 ILE A 160      15.369   7.804  39.429  1.00 32.84           C  
ATOM   1189  CD1 ILE A 160      17.087   6.242  41.368  1.00 36.30           C  
ATOM   1190  N   PRO A 161      14.409   7.501  36.299  1.00 31.14           N  
ATOM   1191  CA  PRO A 161      14.204   8.476  35.239  1.00 31.60           C  
ATOM   1192  C   PRO A 161      14.563   9.891  35.658  1.00 31.49           C  
ATOM   1193  O   PRO A 161      14.322  10.282  36.809  1.00 32.67           O  
ATOM   1194  CB  PRO A 161      12.703   8.364  34.942  1.00 31.66           C  
ATOM   1195  CG  PRO A 161      12.099   7.861  36.195  1.00 32.65           C  
ATOM   1196  CD  PRO A 161      13.135   6.978  36.830  1.00 32.51           C  
ATOM   1197  N   LEU A 162      15.125  10.658  34.737  1.00 32.42           N  
ATOM   1198  CA  LEU A 162      15.333  12.065  34.988  1.00 34.06           C  
ATOM   1199  C   LEU A 162      13.972  12.743  35.130  1.00 36.68           C  
ATOM   1200  O   LEU A 162      12.958  12.259  34.608  1.00 36.59           O  
ATOM   1201  CB  LEU A 162      16.155  12.725  33.882  1.00 34.18           C  
ATOM   1202  CG  LEU A 162      17.581  12.204  33.661  1.00 34.09           C  
ATOM   1203  CD1 LEU A 162      18.284  13.029  32.600  1.00 32.53           C  
ATOM   1204  CD2 LEU A 162      18.390  12.190  34.954  1.00 34.20           C  
ATOM   1205  N   VAL A 163      13.974  13.844  35.874  1.00 36.52           N  
ATOM   1206  CA  VAL A 163      12.798  14.662  36.124  1.00 37.58           C  
ATOM   1207  C   VAL A 163      13.156  16.054  35.616  1.00 37.60           C  
ATOM   1208  O   VAL A 163      14.307  16.474  35.736  1.00 36.67           O  
ATOM   1209  CB  VAL A 163      12.476  14.660  37.641  1.00 39.25           C  
ATOM   1210  CG1 VAL A 163      11.879  15.975  38.106  1.00 40.74           C  
ATOM   1211  CG2 VAL A 163      11.544  13.510  37.980  1.00 40.21           C  
ATOM   1212  N   THR A 164      12.189  16.770  35.045  1.00 36.21           N  
ATOM   1213  CA  THR A 164      12.442  18.130  34.569  1.00 35.65           C  
ATOM   1214  C   THR A 164      12.690  19.049  35.765  1.00 35.19           C  
ATOM   1215  O   THR A 164      12.175  18.821  36.849  1.00 33.45           O  
ATOM   1216  CB  THR A 164      11.267  18.696  33.742  1.00 35.72           C  
ATOM   1217  OG1 THR A 164      10.113  18.814  34.571  1.00 36.21           O  
ATOM   1218  CG2 THR A 164      10.932  17.795  32.548  1.00 36.48           C  
ATOM   1219  N   ASN A 165      13.477  20.090  35.568  1.00 36.51           N  
ATOM   1220  CA  ASN A 165      13.770  21.000  36.662  1.00 39.53           C  
ATOM   1221  C   ASN A 165      12.526  21.773  37.116  1.00 40.05           C  
ATOM   1222  O   ASN A 165      12.469  22.241  38.248  1.00 37.62           O  
ATOM   1223  CB  ASN A 165      14.931  21.930  36.309  1.00 41.34           C  
ATOM   1224  CG  ASN A 165      16.293  21.296  36.602  1.00 43.39           C  
ATOM   1225  OD1 ASN A 165      17.165  21.932  37.193  1.00 44.91           O  
ATOM   1226  ND2 ASN A 165      16.470  20.035  36.213  1.00 46.12           N  
ATOM   1227  N   GLU A 166      11.522  21.873  36.248  1.00 40.79           N  
ATOM   1228  CA  GLU A 166      10.257  22.504  36.618  1.00 41.58           C  
ATOM   1229  C   GLU A 166       9.451  21.577  37.517  1.00 40.79           C  
ATOM   1230  O   GLU A 166       8.888  21.996  38.535  1.00 41.24           O  
ATOM   1231  CB  GLU A 166       9.457  22.869  35.367  1.00 44.42           C  
ATOM   1232  CG  GLU A 166       8.213  23.698  35.666  1.00 47.03           C  
ATOM   1233  CD  GLU A 166       7.790  24.563  34.491  1.00 48.90           C  
ATOM   1234  OE1 GLU A 166       8.679  25.087  33.775  1.00 50.43           O  
ATOM   1235  OE2 GLU A 166       6.569  24.716  34.281  1.00 47.56           O  
ATOM   1236  N   GLU A 167       9.411  20.307  37.138  1.00 39.60           N  
ATOM   1237  CA  GLU A 167       8.783  19.278  37.950  1.00 38.99           C  
ATOM   1238  C   GLU A 167       9.495  19.118  39.286  1.00 37.18           C  
ATOM   1239  O   GLU A 167       8.849  18.912  40.311  1.00 36.70           O  
ATOM   1240  CB  GLU A 167       8.798  17.945  37.202  1.00 42.28           C  
ATOM   1241  CG  GLU A 167       8.213  16.755  37.954  1.00 44.57           C  
ATOM   1242  CD  GLU A 167       6.753  16.942  38.326  1.00 47.24           C  
ATOM   1243  OE1 GLU A 167       6.069  17.795  37.713  1.00 50.43           O  
ATOM   1244  OE2 GLU A 167       6.287  16.231  39.240  1.00 50.11           O  
ATOM   1245  N   CYS A 168      10.825  19.192  39.264  1.00 32.98           N  
ATOM   1246  CA  CYS A 168      11.612  19.034  40.481  1.00 32.33           C  
ATOM   1247  C   CYS A 168      11.390  20.217  41.427  1.00 31.02           C  
ATOM   1248  O   CYS A 168      11.264  20.022  42.634  1.00 31.95           O  
ATOM   1249  CB  CYS A 168      13.095  18.896  40.147  1.00 30.27           C  
ATOM   1250  SG  CYS A 168      14.110  18.336  41.535  1.00 30.47           S  
ATOM   1251  N   GLN A 169      11.345  21.428  40.869  1.00 30.49           N  
ATOM   1252  CA  GLN A 169      11.113  22.645  41.655  1.00 30.78           C  
ATOM   1253  C   GLN A 169       9.771  22.631  42.403  1.00 31.96           C  
ATOM   1254  O   GLN A 169       9.685  23.154  43.514  1.00 31.78           O  
ATOM   1255  CB  GLN A 169      11.197  23.890  40.767  1.00 30.98           C  
ATOM   1256  CG  GLN A 169      11.090  25.227  41.510  1.00 30.20           C  
ATOM   1257  CD  GLN A 169      12.161  25.425  42.571  1.00 29.40           C  
ATOM   1258  OE1 GLN A 169      13.216  26.014  42.306  1.00 27.76           O  
ATOM   1259  NE2 GLN A 169      11.890  24.953  43.787  1.00 29.51           N  
ATOM   1260  N   LYS A 170       8.735  22.045  41.799  1.00 33.45           N  
ATOM   1261  CA  LYS A 170       7.436  21.869  42.489  1.00 35.01           C  
ATOM   1262  C   LYS A 170       7.502  20.916  43.674  1.00 34.11           C  
ATOM   1263  O   LYS A 170       6.677  20.998  44.585  1.00 32.73           O  
ATOM   1264  CB  LYS A 170       6.357  21.368  41.528  1.00 37.92           C  
ATOM   1265  CG  LYS A 170       5.865  22.437  40.581  1.00 41.19           C  
ATOM   1266  CD  LYS A 170       4.814  21.906  39.617  1.00 43.85           C  
ATOM   1267  CE  LYS A 170       4.302  23.035  38.736  1.00 46.54           C  
ATOM   1268  NZ  LYS A 170       3.629  22.525  37.512  1.00 48.35           N  
ATOM   1269  N   ARG A 171       8.468  20.005  43.662  1.00 31.04           N  
ATOM   1270  CA  ARG A 171       8.608  19.042  44.745  1.00 30.71           C  
ATOM   1271  C   ARG A 171       9.473  19.569  45.884  1.00 28.84           C  
ATOM   1272  O   ARG A 171       9.487  18.973  46.957  1.00 28.28           O  
ATOM   1273  CB  ARG A 171       9.217  17.744  44.228  1.00 33.03           C  
ATOM   1274  CG  ARG A 171       8.519  17.141  43.020  1.00 36.02           C  
ATOM   1275  CD  ARG A 171       7.063  16.842  43.303  1.00 39.09           C  
ATOM   1276  NE  ARG A 171       6.479  15.967  42.287  1.00 43.33           N  
ATOM   1277  CZ  ARG A 171       5.186  15.930  41.970  1.00 47.39           C  
ATOM   1278  NH1 ARG A 171       4.304  16.729  42.576  1.00 48.08           N  
ATOM   1279  NH2 ARG A 171       4.767  15.091  41.028  1.00 49.08           N  
ATOM   1280  N   TYR A 172      10.206  20.659  45.636  1.00 27.46           N  
ATOM   1281  CA  TYR A 172      11.091  21.275  46.641  1.00 26.91           C  
ATOM   1282  C   TYR A 172      10.833  22.771  46.707  1.00 26.70           C  
ATOM   1283  O   TYR A 172      11.704  23.566  46.387  1.00 27.13           O  
ATOM   1284  CB  TYR A 172      12.567  21.017  46.290  1.00 25.52           C  
ATOM   1285  CG  TYR A 172      12.967  19.602  46.527  1.00 24.43           C  
ATOM   1286  CD1 TYR A 172      13.200  19.142  47.809  1.00 24.01           C  
ATOM   1287  CD2 TYR A 172      13.097  18.702  45.474  1.00 24.24           C  
ATOM   1288  CE1 TYR A 172      13.551  17.831  48.047  1.00 23.72           C  
ATOM   1289  CE2 TYR A 172      13.447  17.380  45.701  1.00 24.02           C  
ATOM   1290  CZ  TYR A 172      13.677  16.954  46.996  1.00 23.91           C  
ATOM   1291  OH  TYR A 172      14.020  15.654  47.268  1.00 24.05           O  
ATOM   1292  N   ARG A 173       9.627  23.150  47.122  1.00 29.30           N  
ATOM   1293  CA  ARG A 173       9.239  24.572  47.158  1.00 32.09           C  
ATOM   1294  C   ARG A 173      10.009  25.426  48.179  1.00 30.93           C  
ATOM   1295  O   ARG A 173      10.026  26.651  48.065  1.00 32.61           O  
ATOM   1296  CB  ARG A 173       7.720  24.721  47.355  1.00 35.96           C  
ATOM   1297  CG  ARG A 173       6.919  23.970  46.300  1.00 41.23           C  
ATOM   1298  CD  ARG A 173       5.525  24.537  46.052  1.00 47.16           C  
ATOM   1299  NE  ARG A 173       4.844  23.816  44.965  1.00 51.09           N  
ATOM   1300  CZ  ARG A 173       3.637  24.111  44.475  1.00 55.13           C  
ATOM   1301  NH1 ARG A 173       2.924  25.123  44.962  1.00 55.37           N  
ATOM   1302  NH2 ARG A 173       3.131  23.378  43.486  1.00 56.38           N  
ATOM   1303  N   GLY A 173A     10.650  24.799  49.165  1.00 30.55           N  
ATOM   1304  CA  GLY A 173A     11.532  25.524  50.089  1.00 29.88           C  
ATOM   1305  C   GLY A 173A     12.978  25.687  49.617  1.00 29.30           C  
ATOM   1306  O   GLY A 173A     13.800  26.292  50.318  1.00 29.96           O  
ATOM   1307  N   HIS A 174      13.282  25.154  48.430  1.00 28.82           N  
ATOM   1308  CA  HIS A 174      14.617  25.249  47.829  1.00 29.07           C  
ATOM   1309  C   HIS A 174      14.597  25.930  46.464  1.00 29.64           C  
ATOM   1310  O   HIS A 174      13.562  26.061  45.825  1.00 30.09           O  
ATOM   1311  CB  HIS A 174      15.212  23.850  47.626  1.00 27.57           C  
ATOM   1312  CG  HIS A 174      15.490  23.112  48.893  1.00 27.45           C  
ATOM   1313  ND1 HIS A 174      14.536  22.364  49.545  1.00 27.39           N  
ATOM   1314  CD2 HIS A 174      16.629  22.973  49.609  1.00 26.86           C  
ATOM   1315  CE1 HIS A 174      15.065  21.829  50.630  1.00 26.25           C  
ATOM   1316  NE2 HIS A 174      16.334  22.181  50.689  1.00 26.51           N  
ATOM   1317  N   LYS A 175      15.772  26.343  46.022  1.00 30.38           N  
ATOM   1318  CA  LYS A 175      15.960  26.762  44.657  1.00 32.62           C  
ATOM   1319  C   LYS A 175      16.607  25.603  43.896  1.00 30.31           C  
ATOM   1320  O   LYS A 175      17.765  25.261  44.138  1.00 29.01           O  
ATOM   1321  CB  LYS A 175      16.825  28.023  44.609  1.00 36.47           C  
ATOM   1322  CG  LYS A 175      17.097  28.559  43.212  1.00 40.79           C  
ATOM   1323  CD  LYS A 175      15.833  28.717  42.386  1.00 43.94           C  
ATOM   1324  CE  LYS A 175      16.109  29.401  41.055  1.00 46.77           C  
ATOM   1325  NZ  LYS A 175      14.866  29.481  40.241  1.00 47.18           N  
ATOM   1326  N   ILE A 176      15.836  24.956  43.026  1.00 28.93           N  
ATOM   1327  CA  ILE A 176      16.396  23.951  42.116  1.00 29.40           C  
ATOM   1328  C   ILE A 176      16.915  24.718  40.893  1.00 29.07           C  
ATOM   1329  O   ILE A 176      16.140  25.225  40.088  1.00 29.37           O  
ATOM   1330  CB  ILE A 176      15.360  22.891  41.693  1.00 28.93           C  
ATOM   1331  CG1 ILE A 176      14.729  22.206  42.917  1.00 29.04           C  
ATOM   1332  CG2 ILE A 176      15.995  21.848  40.783  1.00 29.38           C  
ATOM   1333  CD1 ILE A 176      15.716  21.597  43.908  1.00 28.59           C  
ATOM   1334  N   THR A 177      18.228  24.827  40.786  1.00 28.95           N  
ATOM   1335  CA  THR A 177      18.854  25.630  39.740  1.00 28.38           C  
ATOM   1336  C   THR A 177      19.152  24.795  38.500  1.00 27.29           C  
ATOM   1337  O   THR A 177      19.089  23.564  38.533  1.00 25.53           O  
ATOM   1338  CB  THR A 177      20.176  26.222  40.236  1.00 28.52           C  
ATOM   1339  OG1 THR A 177      21.125  25.174  40.462  1.00 28.98           O  
ATOM   1340  CG2 THR A 177      19.966  27.006  41.529  1.00 30.02           C  
ATOM   1341  N   HIS A 178      19.521  25.472  37.416  1.00 26.79           N  
ATOM   1342  CA  HIS A 178      19.921  24.775  36.178  1.00 27.90           C  
ATOM   1343  C   HIS A 178      21.267  24.035  36.325  1.00 26.90           C  
ATOM   1344  O   HIS A 178      21.646  23.223  35.476  1.00 29.08           O  
ATOM   1345  CB  HIS A 178      19.947  25.742  34.982  1.00 27.48           C  
ATOM   1346  CG  HIS A 178      21.035  26.764  35.050  1.00 27.57           C  
ATOM   1347  ND1 HIS A 178      20.880  27.971  35.698  1.00 27.89           N  
ATOM   1348  CD2 HIS A 178      22.289  26.764  34.546  1.00 27.17           C  
ATOM   1349  CE1 HIS A 178      21.996  28.667  35.597  1.00 28.76           C  
ATOM   1350  NE2 HIS A 178      22.866  27.962  34.898  1.00 28.77           N  
ATOM   1351  N   LYS A 179      21.973  24.307  37.410  1.00 26.23           N  
ATOM   1352  CA  LYS A 179      23.200  23.589  37.751  1.00 26.26           C  
ATOM   1353  C   LYS A 179      22.928  22.356  38.616  1.00 24.42           C  
ATOM   1354  O   LYS A 179      23.858  21.710  39.117  1.00 22.24           O  
ATOM   1355  CB  LYS A 179      24.170  24.542  38.434  1.00 28.53           C  
ATOM   1356  CG  LYS A 179      24.613  25.688  37.520  1.00 30.32           C  
ATOM   1357  CD  LYS A 179      25.811  26.427  38.102  1.00 32.18           C  
ATOM   1358  CE  LYS A 179      26.223  27.639  37.266  1.00 34.00           C  
ATOM   1359  NZ  LYS A 179      26.575  27.307  35.851  1.00 36.40           N  
ATOM   1360  N   MET A 180      21.650  22.026  38.769  1.00 24.07           N  
ATOM   1361  CA  MET A 180      21.226  20.802  39.420  1.00 23.55           C  
ATOM   1362  C   MET A 180      20.434  20.000  38.419  1.00 25.43           C  
ATOM   1363  O   MET A 180      19.887  20.549  37.454  1.00 23.98           O  
ATOM   1364  CB  MET A 180      20.333  21.095  40.644  1.00 23.46           C  
ATOM   1365  CG  MET A 180      21.015  21.878  41.755  1.00 24.05           C  
ATOM   1366  SD  MET A 180      19.893  22.441  43.065  1.00 23.62           S  
ATOM   1367  CE  MET A 180      21.035  23.353  44.106  1.00 24.44           C  
ATOM   1368  N   ILE A 181      20.369  18.698  38.647  1.00 25.48           N  
ATOM   1369  CA  ILE A 181      19.488  17.840  37.871  1.00 27.88           C  
ATOM   1370  C   ILE A 181      18.841  16.805  38.798  1.00 28.34           C  
ATOM   1371  O   ILE A 181      19.469  16.325  39.748  1.00 26.61           O  
ATOM   1372  CB  ILE A 181      20.233  17.211  36.671  1.00 30.29           C  
ATOM   1373  CG1 ILE A 181      19.232  16.521  35.738  1.00 31.97           C  
ATOM   1374  CG2 ILE A 181      21.335  16.265  37.133  1.00 30.01           C  
ATOM   1375  CD1 ILE A 181      19.826  16.119  34.407  1.00 34.49           C  
ATOM   1376  N   CYS A 182      17.576  16.485  38.532  1.00 26.50           N  
ATOM   1377  CA  CYS A 182      16.806  15.619  39.413  1.00 26.78           C  
ATOM   1378  C   CYS A 182      16.422  14.298  38.779  1.00 27.24           C  
ATOM   1379  O   CYS A 182      16.269  14.211  37.572  1.00 26.78           O  
ATOM   1380  CB  CYS A 182      15.541  16.339  39.843  1.00 27.35           C  
ATOM   1381  SG  CYS A 182      15.895  17.900  40.662  1.00 28.31           S  
ATOM   1382  N   ALA A 183      16.225  13.282  39.608  1.00 26.91           N  
ATOM   1383  CA  ALA A 183      15.828  11.961  39.126  1.00 28.17           C  
ATOM   1384  C   ALA A 183      15.048  11.222  40.180  1.00 28.70           C  
ATOM   1385  O   ALA A 183      15.385  11.271  41.356  1.00 29.78           O  
ATOM   1386  CB  ALA A 183      17.050  11.140  38.731  1.00 28.06           C  
ATOM   1387  N   GLY A 184      14.009  10.512  39.757  1.00 29.84           N  
ATOM   1388  CA  GLY A 184      13.190   9.743  40.692  1.00 30.57           C  
ATOM   1389  C   GLY A 184      11.828   9.450  40.100  1.00 31.26           C  
ATOM   1390  O   GLY A 184      11.478  10.002  39.055  1.00 31.55           O  
ATOM   1391  N   TYR A 184A     11.080   8.587  40.779  1.00 31.76           N  
ATOM   1392  CA  TYR A 184A      9.721   8.199  40.377  1.00 34.82           C  
ATOM   1393  C   TYR A 184A      8.695   8.971  41.198  1.00 35.01           C  
ATOM   1394  O   TYR A 184A      8.876   9.142  42.405  1.00 31.64           O  
ATOM   1395  CB  TYR A 184A      9.505   6.704  40.628  1.00 34.96           C  
ATOM   1396  CG  TYR A 184A     10.387   5.777  39.806  1.00 37.66           C  
ATOM   1397  CD1 TYR A 184A     11.672   5.450  40.229  1.00 38.76           C  
ATOM   1398  CD2 TYR A 184A      9.926   5.207  38.611  1.00 39.30           C  
ATOM   1399  CE1 TYR A 184A     12.482   4.604  39.484  1.00 39.18           C  
ATOM   1400  CE2 TYR A 184A     10.730   4.353  37.862  1.00 39.81           C  
ATOM   1401  CZ  TYR A 184A     12.007   4.053  38.308  1.00 39.90           C  
ATOM   1402  OH  TYR A 184A     12.821   3.213  37.581  1.00 40.52           O  
ATOM   1403  N   ARG A 185       7.602   9.406  40.565  1.00 36.63           N  
ATOM   1404  CA  ARG A 185       6.513  10.082  41.295  1.00 38.68           C  
ATOM   1405  C   ARG A 185       6.112   9.316  42.555  1.00 35.28           C  
ATOM   1406  O   ARG A 185       5.893   9.907  43.615  1.00 34.18           O  
ATOM   1407  CB  ARG A 185       5.273  10.270  40.412  1.00 43.33           C  
ATOM   1408  CG  ARG A 185       4.022  10.580  41.230  1.00 49.86           C  
ATOM   1409  CD  ARG A 185       2.910  11.238  40.426  1.00 55.75           C  
ATOM   1410  NE  ARG A 185       2.162  12.202  41.240  1.00 60.69           N  
ATOM   1411  CZ  ARG A 185       1.072  12.858  40.835  1.00 64.63           C  
ATOM   1412  NH1 ARG A 185       0.572  12.664  39.615  1.00 65.86           N  
ATOM   1413  NH2 ARG A 185       0.474  13.715  41.659  1.00 63.69           N  
ATOM   1414  N   GLU A 186       6.007   8.000  42.423  1.00 34.36           N  
ATOM   1415  CA  GLU A 186       5.601   7.132  43.525  1.00 34.59           C  
ATOM   1416  C   GLU A 186       6.747   6.775  44.465  1.00 32.92           C  
ATOM   1417  O   GLU A 186       6.550   6.031  45.419  1.00 32.06           O  
ATOM   1418  CB  GLU A 186       4.953   5.839  42.984  1.00 36.24           C  
ATOM   1419  CG  GLU A 186       5.886   4.882  42.238  0.50 35.77           C  
ATOM   1420  CD  GLU A 186       6.028   5.170  40.747  0.50 36.65           C  
ATOM   1421  OE1 GLU A 186       5.683   6.283  40.285  0.50 35.30           O  
ATOM   1422  OE2 GLU A 186       6.503   4.266  40.024  0.50 37.04           O  
ATOM   1423  N   GLY A 187       7.948   7.284  44.197  1.00 33.35           N  
ATOM   1424  CA  GLY A 187       9.117   6.932  45.003  1.00 33.07           C  
ATOM   1425  C   GLY A 187       9.521   5.484  44.797  1.00 32.56           C  
ATOM   1426  O   GLY A 187       9.163   4.875  43.785  1.00 32.74           O  
ATOM   1427  N   GLY A 188      10.264   4.938  45.757  1.00 30.05           N  
ATOM   1428  CA  GLY A 188      10.637   3.526  45.753  1.00 30.38           C  
ATOM   1429  C   GLY A 188      12.085   3.267  45.365  1.00 28.30           C  
ATOM   1430  O   GLY A 188      12.706   2.346  45.886  1.00 28.56           O  
ATOM   1431  N   LYS A 188A     12.633   4.079  44.463  1.00 28.57           N  
ATOM   1432  CA  LYS A 188A     14.057   3.951  44.081  1.00 28.22           C  
ATOM   1433  C   LYS A 188A     14.795   5.281  44.152  1.00 27.02           C  
ATOM   1434  O   LYS A 188A     14.336   6.272  43.597  1.00 28.12           O  
ATOM   1435  CB  LYS A 188A     14.179   3.371  42.671  1.00 28.27           C  
ATOM   1436  CG  LYS A 188A     13.642   1.957  42.576  1.00 30.35           C  
ATOM   1437  CD  LYS A 188A     13.809   1.399  41.177  1.00 32.01           C  
ATOM   1438  CE  LYS A 188A     13.243  -0.002  41.080  1.00 33.27           C  
ATOM   1439  NZ  LYS A 188A     13.280  -0.480  39.677  1.00 36.21           N  
ATOM   1440  N   ASP A 189      15.950   5.295  44.816  1.00 26.55           N  
ATOM   1441  CA  ASP A 189      16.668   6.541  45.082  1.00 24.71           C  
ATOM   1442  C   ASP A 189      18.062   6.224  45.619  1.00 24.08           C  
ATOM   1443  O   ASP A 189      18.338   5.119  46.079  1.00 22.03           O  
ATOM   1444  CB  ASP A 189      15.868   7.378  46.124  1.00 26.00           C  
ATOM   1445  CG  ASP A 189      16.223   8.876  46.136  1.00 26.34           C  
ATOM   1446  OD1 ASP A 189      17.031   9.342  45.299  1.00 25.69           O  
ATOM   1447  OD2 ASP A 189      15.684   9.607  47.028  1.00 25.97           O  
ATOM   1448  N   ALA A 190      18.945   7.208  45.563  1.00 23.24           N  
ATOM   1449  CA  ALA A 190      20.130   7.182  46.408  1.00 22.55           C  
ATOM   1450  C   ALA A 190      19.714   7.362  47.873  1.00 22.73           C  
ATOM   1451  O   ALA A 190      18.605   7.832  48.167  1.00 23.05           O  
ATOM   1452  CB  ALA A 190      21.073   8.290  45.991  1.00 22.82           C  
ATOM   1453  N   CYS A 191      20.603   6.992  48.787  1.00 22.92           N  
ATOM   1454  CA  CYS A 191      20.429   7.268  50.218  1.00 23.70           C  
ATOM   1455  C   CYS A 191      21.793   7.472  50.872  1.00 23.07           C  
ATOM   1456  O   CYS A 191      22.796   7.621  50.171  1.00 21.18           O  
ATOM   1457  CB  CYS A 191      19.645   6.145  50.902  1.00 25.05           C  
ATOM   1458  SG  CYS A 191      18.844   6.634  52.461  1.00 26.62           S  
ATOM   1459  N   LYS A 192      21.841   7.464  52.206  1.00 23.84           N  
ATOM   1460  CA  LYS A 192      23.076   7.772  52.931  1.00 24.61           C  
ATOM   1461  C   LYS A 192      24.209   6.813  52.588  1.00 23.08           C  
ATOM   1462  O   LYS A 192      24.033   5.603  52.639  1.00 22.64           O  
ATOM   1463  CB  LYS A 192      22.845   7.760  54.442  1.00 27.26           C  
ATOM   1464  CG  LYS A 192      22.036   8.949  54.924  1.00 30.03           C  
ATOM   1465  CD  LYS A 192      21.963   8.986  56.448  1.00 32.41           C  
ATOM   1466  CE  LYS A 192      20.932  10.004  56.926  1.00 34.14           C  
ATOM   1467  NZ  LYS A 192      21.079  11.325  56.255  1.00 36.12           N  
ATOM   1468  N   GLY A 193      25.370   7.369  52.248  1.00 21.47           N  
ATOM   1469  CA  GLY A 193      26.518   6.573  51.819  1.00 20.25           C  
ATOM   1470  C   GLY A 193      26.696   6.560  50.308  1.00 19.54           C  
ATOM   1471  O   GLY A 193      27.760   6.171  49.814  1.00 18.62           O  
ATOM   1472  N   ASP A 194      25.667   6.974  49.565  1.00 18.39           N  
ATOM   1473  CA  ASP A 194      25.770   7.025  48.096  1.00 18.20           C  
ATOM   1474  C   ASP A 194      26.306   8.333  47.581  1.00 17.74           C  
ATOM   1475  O   ASP A 194      26.693   8.425  46.424  1.00 18.16           O  
ATOM   1476  CB  ASP A 194      24.417   6.788  47.434  1.00 18.61           C  
ATOM   1477  CG  ASP A 194      23.893   5.411  47.691  1.00 18.93           C  
ATOM   1478  OD1 ASP A 194      24.693   4.451  47.625  1.00 19.16           O  
ATOM   1479  OD2 ASP A 194      22.686   5.300  47.968  1.00 19.30           O  
ATOM   1480  N   SER A 195      26.295   9.365  48.413  1.00 18.38           N  
ATOM   1481  CA  SER A 195      26.601  10.698  47.914  1.00 17.56           C  
ATOM   1482  C   SER A 195      28.006  10.727  47.345  1.00 17.14           C  
ATOM   1483  O   SER A 195      28.883   9.973  47.766  1.00 15.91           O  
ATOM   1484  CB  SER A 195      26.392  11.758  48.987  1.00 17.95           C  
ATOM   1485  OG  SER A 195      27.433  11.772  49.931  1.00 17.80           O  
ATOM   1486  N   GLY A 196      28.206  11.589  46.360  1.00 16.17           N  
ATOM   1487  CA  GLY A 196      29.478  11.690  45.692  1.00 15.57           C  
ATOM   1488  C   GLY A 196      29.628  10.740  44.514  1.00 15.81           C  
ATOM   1489  O   GLY A 196      30.464  10.969  43.650  1.00 15.90           O  
ATOM   1490  N   GLY A 197      28.838   9.674  44.486  1.00 15.64           N  
ATOM   1491  CA  GLY A 197      28.847   8.738  43.373  1.00 16.04           C  
ATOM   1492  C   GLY A 197      28.145   9.249  42.121  1.00 16.06           C  
ATOM   1493  O   GLY A 197      27.568  10.346  42.105  1.00 15.51           O  
ATOM   1494  N   PRO A 198      28.205   8.455  41.042  1.00 16.86           N  
ATOM   1495  CA  PRO A 198      27.669   8.851  39.753  1.00 17.25           C  
ATOM   1496  C   PRO A 198      26.171   8.653  39.576  1.00 17.36           C  
ATOM   1497  O   PRO A 198      25.579   7.713  40.133  1.00 17.13           O  
ATOM   1498  CB  PRO A 198      28.395   7.913  38.782  1.00 17.35           C  
ATOM   1499  CG  PRO A 198      28.592   6.664  39.557  1.00 16.68           C  
ATOM   1500  CD  PRO A 198      28.825   7.113  40.984  1.00 17.13           C  
ATOM   1501  N   LEU A 198A     25.584   9.545  38.781  1.00 18.26           N  
ATOM   1502  CA  LEU A 198A     24.346   9.272  38.067  1.00 19.31           C  
ATOM   1503  C   LEU A 198A     24.800   9.076  36.618  1.00 20.17           C  
ATOM   1504  O   LEU A 198A     25.210  10.020  35.971  1.00 19.77           O  
ATOM   1505  CB  LEU A 198A     23.360  10.437  38.171  1.00 20.27           C  
ATOM   1506  CG  LEU A 198A     22.044  10.321  37.378  1.00 20.35           C  
ATOM   1507  CD1 LEU A 198A     21.150   9.208  37.903  1.00 20.79           C  
ATOM   1508  CD2 LEU A 198A     21.305  11.639  37.432  1.00 21.25           C  
ATOM   1509  N   SER A 198B     24.766   7.827  36.161  1.00 21.83           N  
ATOM   1510  CA  SER A 198B     25.358   7.426  34.883  1.00 23.04           C  
ATOM   1511  C   SER A 198B     24.256   7.128  33.877  1.00 24.20           C  
ATOM   1512  O   SER A 198B     23.385   6.307  34.143  1.00 24.59           O  
ATOM   1513  CB  SER A 198B     26.205   6.170  35.073  1.00 22.03           C  
ATOM   1514  OG  SER A 198B     27.201   6.359  36.066  1.00 22.66           O  
ATOM   1515  N   CYS A 201      24.326   7.795  32.727  1.00 28.30           N  
ATOM   1516  CA  CYS A 201      23.317   7.654  31.671  1.00 29.12           C  
ATOM   1517  C   CYS A 201      23.943   7.115  30.395  1.00 30.22           C  
ATOM   1518  O   CYS A 201      24.960   7.638  29.928  1.00 28.76           O  
ATOM   1519  CB  CYS A 201      22.650   8.995  31.378  1.00 29.17           C  
ATOM   1520  SG  CYS A 201      21.810   9.749  32.798  1.00 28.41           S  
ATOM   1521  N   LYS A 202      23.316   6.073  29.851  1.00 32.96           N  
ATOM   1522  CA  LYS A 202      23.783   5.413  28.634  1.00 36.45           C  
ATOM   1523  C   LYS A 202      23.094   6.021  27.426  1.00 36.64           C  
ATOM   1524  O   LYS A 202      21.870   6.059  27.359  1.00 34.68           O  
ATOM   1525  CB  LYS A 202      23.481   3.920  28.697  1.00 36.88           C  
ATOM   1526  CG  LYS A 202      24.094   3.099  27.570  1.00 38.93           C  
ATOM   1527  CD  LYS A 202      24.021   1.616  27.899  1.00 39.12           C  
ATOM   1528  CE  LYS A 202      24.484   0.748  26.747  1.00 42.34           C  
ATOM   1529  NZ  LYS A 202      24.522  -0.681  27.166  1.00 42.69           N  
ATOM   1530  N   HIS A 202A     23.890   6.512  26.486  1.00 40.51           N  
ATOM   1531  CA  HIS A 202A     23.352   7.123  25.280  1.00 44.81           C  
ATOM   1532  C   HIS A 202A     24.190   6.772  24.063  1.00 44.95           C  
ATOM   1533  O   HIS A 202A     25.388   7.065  24.027  1.00 43.95           O  
ATOM   1534  CB  HIS A 202A     23.306   8.634  25.439  1.00 46.45           C  
ATOM   1535  CG  HIS A 202A     22.525   9.317  24.366  1.00 50.01           C  
ATOM   1536  ND1 HIS A 202A     21.186   9.069  24.155  1.00 51.61           N  
ATOM   1537  CD2 HIS A 202A     22.893  10.235  23.443  1.00 51.02           C  
ATOM   1538  CE1 HIS A 202A     20.760   9.813  23.149  1.00 53.07           C  
ATOM   1539  NE2 HIS A 202A     21.775  10.530  22.700  1.00 53.64           N  
ATOM   1540  N   ASN A 202B     23.548   6.170  23.062  1.00 47.45           N  
ATOM   1541  CA  ASN A 202B     24.244   5.689  21.869  1.00 45.87           C  
ATOM   1542  C   ASN A 202B     25.446   4.839  22.244  1.00 43.92           C  
ATOM   1543  O   ASN A 202B     26.566   5.109  21.813  1.00 43.53           O  
ATOM   1544  CB  ASN A 202B     24.687   6.861  20.990  1.00 48.62           C  
ATOM   1545  CG  ASN A 202B     23.520   7.623  20.399  1.00 51.12           C  
ATOM   1546  OD1 ASN A 202B     22.400   7.108  20.306  1.00 53.09           O  
ATOM   1547  ND2 ASN A 202B     23.776   8.858  19.990  1.00 52.00           N  
ATOM   1548  N   GLU A 202C     25.201   3.825  23.068  1.00 44.95           N  
ATOM   1549  CA  GLU A 202C     26.235   2.878  23.508  1.00 46.69           C  
ATOM   1550  C   GLU A 202C     27.403   3.506  24.273  1.00 43.86           C  
ATOM   1551  O   GLU A 202C     28.459   2.893  24.382  1.00 42.65           O  
ATOM   1552  CB  GLU A 202C     26.794   2.087  22.308  1.00 49.08           C  
ATOM   1553  CG  GLU A 202C     25.755   1.630  21.292  1.00 52.32           C  
ATOM   1554  CD  GLU A 202C     24.507   1.052  21.935  1.00 56.76           C  
ATOM   1555  OE1 GLU A 202C     24.622   0.320  22.947  1.00 58.41           O  
ATOM   1556  OE2 GLU A 202C     23.402   1.332  21.420  1.00 64.07           O  
ATOM   1557  N   VAL A 202D     27.235   4.721  24.791  1.00 41.83           N  
ATOM   1558  CA  VAL A 202D     28.316   5.376  25.529  1.00 39.79           C  
ATOM   1559  C   VAL A 202D     27.765   5.928  26.841  1.00 36.63           C  
ATOM   1560  O   VAL A 202D     26.751   6.617  26.847  1.00 35.65           O  
ATOM   1561  CB  VAL A 202D     28.977   6.516  24.722  1.00 41.47           C  
ATOM   1562  CG1 VAL A 202D     30.133   7.132  25.503  1.00 41.73           C  
ATOM   1563  CG2 VAL A 202D     29.484   6.015  23.370  1.00 41.01           C  
ATOM   1564  N   TRP A 203      28.448   5.613  27.938  1.00 33.08           N  
ATOM   1565  CA  TRP A 203      28.079   6.114  29.259  1.00 29.44           C  
ATOM   1566  C   TRP A 203      28.634   7.516  29.478  1.00 28.49           C  
ATOM   1567  O   TRP A 203      29.774   7.806  29.114  1.00 28.99           O  
ATOM   1568  CB  TRP A 203      28.601   5.166  30.335  1.00 28.75           C  
ATOM   1569  CG  TRP A 203      27.881   3.856  30.402  1.00 27.74           C  
ATOM   1570  CD1 TRP A 203      28.307   2.656  29.906  1.00 27.87           C  
ATOM   1571  CD2 TRP A 203      26.614   3.608  31.019  1.00 27.42           C  
ATOM   1572  NE1 TRP A 203      27.383   1.680  30.178  1.00 27.20           N  
ATOM   1573  CE2 TRP A 203      26.332   2.238  30.859  1.00 26.80           C  
ATOM   1574  CE3 TRP A 203      25.689   4.415  31.691  1.00 27.82           C  
ATOM   1575  CZ2 TRP A 203      25.170   1.650  31.350  1.00 27.24           C  
ATOM   1576  CZ3 TRP A 203      24.527   3.834  32.176  1.00 27.44           C  
ATOM   1577  CH2 TRP A 203      24.277   2.462  32.010  1.00 27.56           C  
ATOM   1578  N   HIS A 204      27.820   8.388  30.073  1.00 27.96           N  
ATOM   1579  CA  HIS A 204      28.234   9.737  30.412  1.00 26.65           C  
ATOM   1580  C   HIS A 204      27.940  10.003  31.871  1.00 23.40           C  
ATOM   1581  O   HIS A 204      26.950   9.506  32.393  1.00 21.94           O  
ATOM   1582  CB  HIS A 204      27.478  10.753  29.563  1.00 30.68           C  
ATOM   1583  CG  HIS A 204      27.832  10.691  28.113  1.00 35.09           C  
ATOM   1584  ND1 HIS A 204      27.218   9.820  27.237  1.00 37.59           N  
ATOM   1585  CD2 HIS A 204      28.757  11.365  27.392  1.00 37.20           C  
ATOM   1586  CE1 HIS A 204      27.738   9.976  26.033  1.00 37.60           C  
ATOM   1587  NE2 HIS A 204      28.675  10.905  26.099  1.00 37.70           N  
ATOM   1588  N   LEU A 209      28.804  10.792  32.502  1.00 21.68           N  
ATOM   1589  CA  LEU A 209      28.631  11.188  33.901  1.00 20.83           C  
ATOM   1590  C   LEU A 209      27.720  12.404  33.961  1.00 20.13           C  
ATOM   1591  O   LEU A 209      28.173  13.540  33.895  1.00 21.61           O  
ATOM   1592  CB  LEU A 209      29.969  11.485  34.543  1.00 21.28           C  
ATOM   1593  CG  LEU A 209      29.953  11.779  36.040  1.00 20.91           C  
ATOM   1594  CD1 LEU A 209      29.259  10.673  36.824  1.00 20.45           C  
ATOM   1595  CD2 LEU A 209      31.380  11.991  36.496  1.00 21.28           C  
ATOM   1596  N   VAL A 210      26.431  12.140  34.082  1.00 20.90           N  
ATOM   1597  CA  VAL A 210      25.411  13.183  34.044  1.00 20.88           C  
ATOM   1598  C   VAL A 210      25.240  13.924  35.369  1.00 20.25           C  
ATOM   1599  O   VAL A 210      25.120  15.148  35.377  1.00 18.69           O  
ATOM   1600  CB  VAL A 210      24.065  12.595  33.593  1.00 22.82           C  
ATOM   1601  CG1 VAL A 210      22.911  13.557  33.868  1.00 23.76           C  
ATOM   1602  CG2 VAL A 210      24.140  12.251  32.114  1.00 23.95           C  
ATOM   1603  N   GLY A 211      25.237  13.187  36.475  1.00 20.14           N  
ATOM   1604  CA  GLY A 211      25.064  13.781  37.800  1.00 19.71           C  
ATOM   1605  C   GLY A 211      26.008  13.218  38.847  1.00 19.25           C  
ATOM   1606  O   GLY A 211      26.588  12.131  38.671  1.00 18.56           O  
ATOM   1607  N   ILE A 212      26.174  13.993  39.921  1.00 18.39           N  
ATOM   1608  CA  ILE A 212      26.805  13.557  41.160  1.00 18.38           C  
ATOM   1609  C   ILE A 212      25.740  13.559  42.262  1.00 18.28           C  
ATOM   1610  O   ILE A 212      25.122  14.591  42.537  1.00 17.65           O  
ATOM   1611  CB  ILE A 212      27.941  14.498  41.590  1.00 18.53           C  
ATOM   1612  CG1 ILE A 212      28.974  14.652  40.482  1.00 19.34           C  
ATOM   1613  CG2 ILE A 212      28.614  13.987  42.863  1.00 18.37           C  
ATOM   1614  CD1 ILE A 212      29.846  15.866  40.655  1.00 20.18           C  
ATOM   1615  N   THR A 213      25.544  12.404  42.887  1.00 17.99           N  
ATOM   1616  CA  THR A 213      24.624  12.237  44.009  1.00 17.72           C  
ATOM   1617  C   THR A 213      24.867  13.268  45.104  1.00 17.30           C  
ATOM   1618  O   THR A 213      25.953  13.348  45.678  1.00 16.68           O  
ATOM   1619  CB  THR A 213      24.711  10.806  44.557  1.00 17.98           C  
ATOM   1620  OG1 THR A 213      24.450   9.902  43.476  1.00 18.35           O  
ATOM   1621  CG2 THR A 213      23.688  10.567  45.645  1.00 17.94           C  
ATOM   1622  N   SER A 214      23.862  14.104  45.359  1.00 18.59           N  
ATOM   1623  CA  SER A 214      24.084  15.283  46.191  1.00 17.94           C  
ATOM   1624  C   SER A 214      23.170  15.350  47.419  1.00 19.61           C  
ATOM   1625  O   SER A 214      23.656  15.297  48.560  1.00 18.63           O  
ATOM   1626  CB  SER A 214      23.966  16.542  45.341  1.00 18.76           C  
ATOM   1627  OG  SER A 214      24.258  17.718  46.091  1.00 18.88           O  
ATOM   1628  N   TRP A 215      21.863  15.456  47.197  1.00 19.49           N  
ATOM   1629  CA  TRP A 215      20.913  15.577  48.318  1.00 20.49           C  
ATOM   1630  C   TRP A 215      19.482  15.221  47.930  1.00 21.05           C  
ATOM   1631  O   TRP A 215      19.139  15.131  46.756  1.00 20.80           O  
ATOM   1632  CB  TRP A 215      20.956  17.000  48.925  1.00 19.81           C  
ATOM   1633  CG  TRP A 215      20.490  18.087  47.998  1.00 20.27           C  
ATOM   1634  CD1 TRP A 215      21.227  18.707  47.029  1.00 19.73           C  
ATOM   1635  CD2 TRP A 215      19.172  18.666  47.927  1.00 20.91           C  
ATOM   1636  NE1 TRP A 215      20.462  19.627  46.376  1.00 20.87           N  
ATOM   1637  CE2 TRP A 215      19.198  19.625  46.902  1.00 20.62           C  
ATOM   1638  CE3 TRP A 215      17.980  18.475  48.649  1.00 20.92           C  
ATOM   1639  CZ2 TRP A 215      18.077  20.398  46.567  1.00 21.79           C  
ATOM   1640  CZ3 TRP A 215      16.865  19.238  48.305  1.00 21.03           C  
ATOM   1641  CH2 TRP A 215      16.925  20.180  47.281  1.00 20.91           C  
ATOM   1642  N   GLY A 216      18.642  15.067  48.946  1.00 21.36           N  
ATOM   1643  CA  GLY A 216      17.210  14.884  48.757  1.00 21.96           C  
ATOM   1644  C   GLY A 216      16.531  14.925  50.113  1.00 22.79           C  
ATOM   1645  O   GLY A 216      17.208  14.868  51.145  1.00 23.40           O  
ATOM   1646  N   GLU A 217      15.205  15.053  50.134  1.00 23.33           N  
ATOM   1647  CA  GLU A 217      14.488  14.986  51.417  1.00 24.82           C  
ATOM   1648  C   GLU A 217      14.142  13.557  51.713  1.00 24.85           C  
ATOM   1649  O   GLU A 217      13.239  13.009  51.099  1.00 24.79           O  
ATOM   1650  CB  GLU A 217      13.195  15.818  51.411  1.00 26.71           C  
ATOM   1651  CG  GLU A 217      12.483  15.808  52.764  1.00 27.32           C  
ATOM   1652  CD  GLU A 217      13.389  16.274  53.893  1.00 29.00           C  
ATOM   1653  OE1 GLU A 217      13.943  17.380  53.763  1.00 32.43           O  
ATOM   1654  OE2 GLU A 217      13.564  15.542  54.893  1.00 28.12           O  
ATOM   1655  N   GLY A 218      14.840  12.958  52.669  1.00 24.38           N  
ATOM   1656  CA  GLY A 218      14.723  11.541  52.936  1.00 25.55           C  
ATOM   1657  C   GLY A 218      15.244  10.732  51.758  1.00 26.00           C  
ATOM   1658  O   GLY A 218      15.980  11.252  50.915  1.00 26.83           O  
ATOM   1659  N   CYS A 219      14.881   9.461  51.704  1.00 26.19           N  
ATOM   1660  CA  CYS A 219      15.313   8.583  50.609  1.00 27.11           C  
ATOM   1661  C   CYS A 219      14.126   7.871  49.976  1.00 26.45           C  
ATOM   1662  O   CYS A 219      13.362   7.224  50.677  1.00 26.98           O  
ATOM   1663  CB  CYS A 219      16.288   7.529  51.137  1.00 27.31           C  
ATOM   1664  SG  CYS A 219      17.730   8.244  51.959  1.00 28.56           S  
ATOM   1665  N   ALA A 220      13.973   8.007  48.661  1.00 26.25           N  
ATOM   1666  CA  ALA A 220      12.968   7.240  47.887  1.00 27.50           C  
ATOM   1667  C   ALA A 220      11.507   7.595  48.187  1.00 27.92           C  
ATOM   1668  O   ALA A 220      10.596   6.816  47.858  1.00 26.31           O  
ATOM   1669  CB  ALA A 220      13.180   5.741  48.078  1.00 27.46           C  
ATOM   1670  N   GLN A 221      11.277   8.768  48.770  1.00 27.22           N  
ATOM   1671  CA  GLN A 221       9.935   9.166  49.139  1.00 27.47           C  
ATOM   1672  C   GLN A 221       9.131   9.597  47.934  1.00 27.87           C  
ATOM   1673  O   GLN A 221       9.663  10.118  46.963  1.00 27.76           O  
ATOM   1674  CB  GLN A 221       9.966  10.307  50.154  1.00 27.37           C  
ATOM   1675  CG  GLN A 221      10.629   9.942  51.466  1.00 27.26           C  
ATOM   1676  CD  GLN A 221      10.224  10.876  52.583  1.00 28.38           C  
ATOM   1677  OE1 GLN A 221       9.388  10.533  53.410  1.00 29.54           O  
ATOM   1678  NE2 GLN A 221      10.796  12.071  52.597  1.00 29.15           N  
ATOM   1679  N   ARG A 222       7.824   9.387  48.027  1.00 30.89           N  
ATOM   1680  CA  ARG A 222       6.866   9.876  47.049  1.00 32.33           C  
ATOM   1681  C   ARG A 222       7.086  11.360  46.730  1.00 30.04           C  
ATOM   1682  O   ARG A 222       7.252  12.170  47.627  1.00 29.70           O  
ATOM   1683  CB  ARG A 222       5.446   9.618  47.602  1.00 37.29           C  
ATOM   1684  CG  ARG A 222       4.305  10.403  46.967  1.00 43.47           C  
ATOM   1685  CD  ARG A 222       2.943   9.965  47.511  1.00 45.88           C  
ATOM   1686  NE  ARG A 222       2.898   8.516  47.713  1.00 50.70           N  
ATOM   1687  CZ  ARG A 222       2.633   7.615  46.765  1.00 53.44           C  
ATOM   1688  NH1 ARG A 222       2.352   7.992  45.519  1.00 52.21           N  
ATOM   1689  NH2 ARG A 222       2.646   6.318  47.072  1.00 54.74           N  
ATOM   1690  N   GLU A 223       7.119  11.700  45.449  1.00 29.15           N  
ATOM   1691  CA  GLU A 223       7.220  13.092  44.997  1.00 31.74           C  
ATOM   1692  C   GLU A 223       8.403  13.855  45.604  1.00 30.50           C  
ATOM   1693  O   GLU A 223       8.304  15.056  45.870  1.00 28.37           O  
ATOM   1694  CB  GLU A 223       5.917  13.840  45.298  1.00 35.70           C  
ATOM   1695  CG  GLU A 223       4.684  13.136  44.762  1.00 39.04           C  
ATOM   1696  CD  GLU A 223       3.409  13.924  44.984  1.00 42.98           C  
ATOM   1697  OE1 GLU A 223       3.193  14.437  46.102  1.00 42.96           O  
ATOM   1698  OE2 GLU A 223       2.619  14.026  44.020  1.00 49.17           O  
ATOM   1699  N   ARG A 224       9.513  13.150  45.818  1.00 27.91           N  
ATOM   1700  CA  ARG A 224      10.744  13.750  46.332  1.00 26.22           C  
ATOM   1701  C   ARG A 224      11.911  13.156  45.555  1.00 26.03           C  
ATOM   1702  O   ARG A 224      12.571  12.250  46.038  1.00 25.23           O  
ATOM   1703  CB  ARG A 224      10.909  13.460  47.829  1.00 27.05           C  
ATOM   1704  CG  ARG A 224       9.924  14.192  48.735  1.00 26.64           C  
ATOM   1705  CD  ARG A 224      10.191  15.695  48.785  1.00 26.91           C  
ATOM   1706  NE  ARG A 224       9.592  16.294  49.990  1.00 26.89           N  
ATOM   1707  CZ  ARG A 224       9.863  17.504  50.470  1.00 28.15           C  
ATOM   1708  NH1 ARG A 224      10.714  18.301  49.858  1.00 29.22           N  
ATOM   1709  NH2 ARG A 224       9.263  17.927  51.582  1.00 29.96           N  
ATOM   1710  N   PRO A 225      12.151  13.663  44.334  1.00 26.07           N  
ATOM   1711  CA  PRO A 225      13.271  13.211  43.499  1.00 25.39           C  
ATOM   1712  C   PRO A 225      14.631  13.448  44.152  1.00 24.97           C  
ATOM   1713  O   PRO A 225      14.807  14.436  44.898  1.00 24.94           O  
ATOM   1714  CB  PRO A 225      13.168  14.094  42.263  1.00 26.40           C  
ATOM   1715  CG  PRO A 225      11.782  14.635  42.265  1.00 26.61           C  
ATOM   1716  CD  PRO A 225      11.371  14.727  43.685  1.00 25.99           C  
ATOM   1717  N   GLY A 226      15.591  12.572  43.866  1.00 22.92           N  
ATOM   1718  CA  GLY A 226      16.974  12.845  44.247  1.00 22.75           C  
ATOM   1719  C   GLY A 226      17.513  14.027  43.468  1.00 21.60           C  
ATOM   1720  O   GLY A 226      17.110  14.265  42.330  1.00 23.25           O  
ATOM   1721  N   VAL A 227      18.411  14.778  44.086  1.00 20.54           N  
ATOM   1722  CA  VAL A 227      18.965  15.960  43.476  1.00 21.16           C  
ATOM   1723  C   VAL A 227      20.448  15.725  43.274  1.00 20.51           C  
ATOM   1724  O   VAL A 227      21.151  15.344  44.214  1.00 20.23           O  
ATOM   1725  CB  VAL A 227      18.719  17.232  44.320  1.00 21.00           C  
ATOM   1726  CG1 VAL A 227      19.158  18.463  43.543  1.00 21.22           C  
ATOM   1727  CG2 VAL A 227      17.252  17.342  44.695  1.00 21.11           C  
ATOM   1728  N   TYR A 228      20.892  15.957  42.038  1.00 19.78           N  
ATOM   1729  CA  TYR A 228      22.253  15.687  41.590  1.00 19.22           C  
ATOM   1730  C   TYR A 228      22.920  16.947  41.044  1.00 19.39           C  
ATOM   1731  O   TYR A 228      22.264  17.837  40.479  1.00 20.64           O  
ATOM   1732  CB  TYR A 228      22.259  14.588  40.510  1.00 18.48           C  
ATOM   1733  CG  TYR A 228      21.634  13.288  40.972  1.00 18.76           C  
ATOM   1734  CD1 TYR A 228      20.249  13.159  41.109  1.00 18.61           C  
ATOM   1735  CD2 TYR A 228      22.418  12.179  41.284  1.00 18.59           C  
ATOM   1736  CE1 TYR A 228      19.678  11.983  41.567  1.00 18.56           C  
ATOM   1737  CE2 TYR A 228      21.847  10.997  41.725  1.00 18.78           C  
ATOM   1738  CZ  TYR A 228      20.483  10.901  41.870  1.00 18.51           C  
ATOM   1739  OH  TYR A 228      19.937   9.717  42.312  1.00 18.54           O  
ATOM   1740  N   THR A 229      24.229  17.032  41.230  1.00 19.11           N  
ATOM   1741  CA  THR A 229      25.006  18.089  40.620  1.00 19.45           C  
ATOM   1742  C   THR A 229      24.959  17.842  39.107  1.00 19.84           C  
ATOM   1743  O   THR A 229      25.202  16.727  38.650  1.00 19.29           O  
ATOM   1744  CB  THR A 229      26.436  18.080  41.152  1.00 19.20           C  
ATOM   1745  OG1 THR A 229      26.407  18.321  42.573  1.00 20.26           O  
ATOM   1746  CG2 THR A 229      27.276  19.142  40.495  1.00 18.85           C  
ATOM   1747  N   ASN A 230      24.600  18.879  38.351  1.00 21.03           N  
ATOM   1748  CA  ASN A 230      24.470  18.769  36.896  1.00 21.47           C  
ATOM   1749  C   ASN A 230      25.851  18.972  36.274  1.00 21.10           C  
ATOM   1750  O   ASN A 230      26.310  20.106  36.080  1.00 21.55           O  
ATOM   1751  CB  ASN A 230      23.458  19.801  36.400  1.00 23.05           C  
ATOM   1752  CG  ASN A 230      23.132  19.637  34.932  1.00 23.76           C  
ATOM   1753  OD1 ASN A 230      23.388  18.589  34.341  1.00 23.95           O  
ATOM   1754  ND2 ASN A 230      22.565  20.678  34.338  1.00 24.54           N  
ATOM   1755  N   VAL A 231      26.528  17.858  36.012  1.00 20.93           N  
ATOM   1756  CA  VAL A 231      27.962  17.855  35.694  1.00 21.35           C  
ATOM   1757  C   VAL A 231      28.329  18.696  34.453  1.00 21.65           C  
ATOM   1758  O   VAL A 231      29.367  19.364  34.451  1.00 20.42           O  
ATOM   1759  CB  VAL A 231      28.493  16.413  35.549  1.00 20.78           C  
ATOM   1760  CG1 VAL A 231      29.964  16.386  35.121  1.00 20.93           C  
ATOM   1761  CG2 VAL A 231      28.336  15.667  36.875  1.00 20.72           C  
ATOM   1762  N   VAL A 232      27.459  18.701  33.454  1.00 23.13           N  
ATOM   1763  CA  VAL A 232      27.710  19.457  32.211  1.00 24.83           C  
ATOM   1764  C   VAL A 232      27.957  20.935  32.501  1.00 25.42           C  
ATOM   1765  O   VAL A 232      28.764  21.578  31.816  1.00 24.54           O  
ATOM   1766  CB  VAL A 232      26.605  19.228  31.140  1.00 26.20           C  
ATOM   1767  CG1 VAL A 232      25.280  19.870  31.522  1.00 26.75           C  
ATOM   1768  CG2 VAL A 232      27.061  19.734  29.769  1.00 27.21           C  
ATOM   1769  N   GLU A 233      27.330  21.460  33.557  1.00 24.79           N  
ATOM   1770  CA  GLU A 233      27.552  22.841  33.966  1.00 26.05           C  
ATOM   1771  C   GLU A 233      28.929  23.108  34.550  1.00 25.86           C  
ATOM   1772  O   GLU A 233      29.286  24.268  34.799  1.00 26.63           O  
ATOM   1773  CB  GLU A 233      26.470  23.267  34.964  1.00 27.51           C  
ATOM   1774  CG  GLU A 233      25.113  23.430  34.298  1.00 29.39           C  
ATOM   1775  CD  GLU A 233      25.114  24.588  33.325  1.00 32.44           C  
ATOM   1776  OE1 GLU A 233      25.553  25.699  33.718  1.00 33.63           O  
ATOM   1777  OE2 GLU A 233      24.703  24.370  32.172  1.00 34.36           O  
ATOM   1778  N   TYR A 234      29.703  22.047  34.768  1.00 24.56           N  
ATOM   1779  CA  TYR A 234      31.009  22.163  35.404  1.00 23.86           C  
ATOM   1780  C   TYR A 234      32.175  21.648  34.549  1.00 23.84           C  
ATOM   1781  O   TYR A 234      33.282  21.519  35.045  1.00 23.81           O  
ATOM   1782  CB  TYR A 234      30.988  21.455  36.767  1.00 23.57           C  
ATOM   1783  CG  TYR A 234      30.005  22.079  37.732  1.00 22.75           C  
ATOM   1784  CD1 TYR A 234      30.375  23.161  38.517  1.00 22.70           C  
ATOM   1785  CD2 TYR A 234      28.699  21.617  37.819  1.00 22.98           C  
ATOM   1786  CE1 TYR A 234      29.478  23.758  39.384  1.00 22.85           C  
ATOM   1787  CE2 TYR A 234      27.786  22.208  38.681  1.00 22.66           C  
ATOM   1788  CZ  TYR A 234      28.188  23.271  39.466  1.00 22.85           C  
ATOM   1789  OH  TYR A 234      27.289  23.857  40.322  1.00 23.71           O  
ATOM   1790  N   VAL A 235      31.956  21.396  33.266  1.00 25.10           N  
ATOM   1791  CA  VAL A 235      33.066  20.905  32.445  1.00 26.11           C  
ATOM   1792  C   VAL A 235      34.176  21.951  32.314  1.00 25.17           C  
ATOM   1793  O   VAL A 235      35.358  21.619  32.392  1.00 23.93           O  
ATOM   1794  CB  VAL A 235      32.604  20.339  31.082  1.00 27.62           C  
ATOM   1795  CG1 VAL A 235      31.687  19.151  31.296  1.00 28.00           C  
ATOM   1796  CG2 VAL A 235      31.927  21.388  30.223  1.00 29.59           C  
ATOM   1797  N   ASP A 236      33.814  23.227  32.175  1.00 25.76           N  
ATOM   1798  CA  ASP A 236      34.834  24.274  32.164  1.00 26.42           C  
ATOM   1799  C   ASP A 236      35.617  24.312  33.482  1.00 25.29           C  
ATOM   1800  O   ASP A 236      36.843  24.377  33.470  1.00 24.84           O  
ATOM   1801  CB  ASP A 236      34.234  25.647  31.849  1.00 27.35           C  
ATOM   1802  CG  ASP A 236      33.646  25.724  30.439  1.00 29.51           C  
ATOM   1803  OD1 ASP A 236      34.116  25.009  29.524  1.00 30.53           O  
ATOM   1804  OD2 ASP A 236      32.685  26.500  30.242  1.00 31.90           O  
ATOM   1805  N   TRP A 237      34.917  24.261  34.613  1.00 23.69           N  
ATOM   1806  CA  TRP A 237      35.579  24.227  35.918  1.00 22.85           C  
ATOM   1807  C   TRP A 237      36.526  23.019  36.040  1.00 22.47           C  
ATOM   1808  O   TRP A 237      37.678  23.158  36.467  1.00 23.86           O  
ATOM   1809  CB  TRP A 237      34.530  24.228  37.043  1.00 23.27           C  
ATOM   1810  CG  TRP A 237      35.098  24.209  38.437  1.00 23.42           C  
ATOM   1811  CD1 TRP A 237      35.517  25.278  39.183  1.00 24.14           C  
ATOM   1812  CD2 TRP A 237      35.308  23.050  39.249  1.00 23.28           C  
ATOM   1813  NE1 TRP A 237      35.976  24.849  40.407  1.00 24.72           N  
ATOM   1814  CE2 TRP A 237      35.848  23.487  40.477  1.00 23.70           C  
ATOM   1815  CE3 TRP A 237      35.086  21.684  39.058  1.00 23.22           C  
ATOM   1816  CZ2 TRP A 237      36.184  22.604  41.501  1.00 23.58           C  
ATOM   1817  CZ3 TRP A 237      35.403  20.809  40.092  1.00 22.83           C  
ATOM   1818  CH2 TRP A 237      35.930  21.271  41.294  1.00 22.27           C  
ATOM   1819  N   ILE A 238      36.042  21.846  35.663  1.00 22.63           N  
ATOM   1820  CA  ILE A 238      36.855  20.628  35.724  1.00 22.84           C  
ATOM   1821  C   ILE A 238      38.130  20.769  34.889  1.00 24.12           C  
ATOM   1822  O   ILE A 238      39.229  20.432  35.339  1.00 23.81           O  
ATOM   1823  CB  ILE A 238      36.072  19.393  35.239  1.00 22.06           C  
ATOM   1824  CG1 ILE A 238      34.948  19.060  36.220  1.00 21.46           C  
ATOM   1825  CG2 ILE A 238      36.997  18.185  35.125  1.00 22.76           C  
ATOM   1826  CD1 ILE A 238      33.960  18.052  35.719  1.00 20.59           C  
ATOM   1827  N   LEU A 239      37.975  21.265  33.669  1.00 25.92           N  
ATOM   1828  CA  LEU A 239      39.124  21.486  32.797  1.00 27.39           C  
ATOM   1829  C   LEU A 239      40.116  22.452  33.444  1.00 27.93           C  
ATOM   1830  O   LEU A 239      41.317  22.184  33.490  1.00 27.91           O  
ATOM   1831  CB  LEU A 239      38.654  21.987  31.423  1.00 28.71           C  
ATOM   1832  CG  LEU A 239      39.754  22.314  30.395  1.00 30.19           C  
ATOM   1833  CD1 LEU A 239      40.665  21.105  30.169  1.00 29.94           C  
ATOM   1834  CD2 LEU A 239      39.117  22.795  29.093  1.00 28.76           C  
ATOM   1835  N   GLU A 240      39.620  23.559  33.989  1.00 29.63           N  
ATOM   1836  CA  GLU A 240      40.487  24.538  34.638  1.00 32.51           C  
ATOM   1837  C   GLU A 240      41.231  23.916  35.810  1.00 33.86           C  
ATOM   1838  O   GLU A 240      42.448  24.103  35.963  1.00 33.15           O  
ATOM   1839  CB  GLU A 240      39.660  25.733  35.118  1.00 36.30           C  
ATOM   1840  CG  GLU A 240      40.447  26.858  35.773  1.00 41.03           C  
ATOM   1841  CD  GLU A 240      39.533  27.891  36.419  1.00 46.70           C  
ATOM   1842  OE1 GLU A 240      38.370  28.026  35.968  1.00 50.61           O  
ATOM   1843  OE2 GLU A 240      39.969  28.556  37.387  1.00 51.54           O  
ATOM   1844  N   LYS A 241      40.497  23.168  36.632  1.00 33.40           N  
ATOM   1845  CA  LYS A 241      41.051  22.622  37.868  1.00 34.99           C  
ATOM   1846  C   LYS A 241      41.985  21.443  37.668  1.00 33.50           C  
ATOM   1847  O   LYS A 241      42.866  21.233  38.492  1.00 36.74           O  
ATOM   1848  CB  LYS A 241      39.924  22.259  38.848  1.00 34.29           C  
ATOM   1849  CG  LYS A 241      39.205  23.470  39.429  1.00 34.70           C  
ATOM   1850  CD  LYS A 241      40.162  24.419  40.139  1.00 35.46           C  
ATOM   1851  CE  LYS A 241      39.450  25.588  40.788  1.00 36.84           C  
ATOM   1852  NZ  LYS A 241      40.424  26.563  41.375  1.00 37.03           N  
ATOM   1853  N   THR A 242      41.807  20.680  36.592  1.00 33.70           N  
ATOM   1854  CA  THR A 242      42.678  19.528  36.328  1.00 35.12           C  
ATOM   1855  C   THR A 242      43.952  19.890  35.525  1.00 40.57           C  
ATOM   1856  O   THR A 242      44.721  19.000  35.157  1.00 38.40           O  
ATOM   1857  CB  THR A 242      41.917  18.365  35.652  1.00 33.10           C  
ATOM   1858  OG1 THR A 242      41.243  18.820  34.475  1.00 32.48           O  
ATOM   1859  CG2 THR A 242      40.880  17.790  36.598  1.00 32.86           C  
ATOM   1860  N   GLN A 243      44.183  21.186  35.286  1.00 46.72           N  
ATOM   1861  CA  GLN A 243      45.435  21.656  34.652  1.00 50.22           C  
ATOM   1862  C   GLN A 243      46.596  21.666  35.629  1.00 53.98           C  
ATOM   1863  O   GLN A 243      46.444  22.054  36.792  1.00 54.45           O  
ATOM   1864  CB  GLN A 243      45.288  23.074  34.098  1.00 51.56           C  
ATOM   1865  CG  GLN A 243      44.255  23.239  33.000  1.00 52.79           C  
ATOM   1866  CD  GLN A 243      44.371  22.189  31.909  1.00 55.29           C  
ATOM   1867  OE1 GLN A 243      44.873  22.468  30.820  1.00 58.51           O  
ATOM   1868  NE2 GLN A 243      43.907  20.973  32.196  1.00 55.57           N  
ATOM   1869  N   ALA A 244      47.765  21.263  35.140  1.00 55.38           N  
ATOM   1870  CA  ALA A 244      48.985  21.335  35.930  1.00 56.98           C  
ATOM   1871  C   ALA A 244      49.308  22.794  36.276  1.00 57.64           C  
ATOM   1872  O   ALA A 244      48.827  23.720  35.611  1.00 57.16           O  
ATOM   1873  CB  ALA A 244      50.145  20.691  35.180  1.00 57.00           C  
ATOM   1874  N   VAL A 245      50.098  22.961  37.339  1.00 59.47           N  
ATOM   1875  CA  VAL A 245      50.628  24.258  37.815  1.00 60.13           C  
ATOM   1876  C   VAL A 245      50.066  25.482  37.082  1.00 63.99           C  
ATOM   1877  O   VAL A 245      49.019  26.017  37.462  1.00 68.77           O  
ATOM   1878  CB  VAL A 245      52.183  24.253  37.777  1.00 60.09           C  
ATOM   1879  CG1 VAL A 245      52.770  25.570  38.288  1.00 58.54           C  
ATOM   1880  CG2 VAL A 245      52.706  23.075  38.596  1.00 59.30           C  
ATOM   1881  OXT VAL A 245      50.627  25.972  36.101  1.00 66.59           O  
TER    1882      VAL A 245                                                      
HETATM 1883  C1  GOL A1483      31.371   8.554  57.641  1.00 50.80           C  
HETATM 1884  O1  GOL A1483      32.655   8.347  58.227  1.00 48.93           O  
HETATM 1885  C2  GOL A1483      30.393   9.270  58.576  1.00 52.90           C  
HETATM 1886  O2  GOL A1483      29.575  10.151  57.792  1.00 52.33           O  
HETATM 1887  C3  GOL A1483      29.544   8.252  59.340  1.00 52.64           C  
HETATM 1888  O3  GOL A1483      30.182   7.917  60.573  1.00 56.17           O  
HETATM 1889  C1  GOL A1484      24.327  15.901  51.667  1.00 27.30           C  
HETATM 1890  O1  GOL A1484      23.030  15.735  51.104  1.00 25.21           O  
HETATM 1891  C2  GOL A1484      24.224  16.763  52.915  1.00 28.56           C  
HETATM 1892  O2  GOL A1484      23.366  16.095  53.845  1.00 30.34           O  
HETATM 1893  C3  GOL A1484      25.592  16.973  53.549  1.00 30.37           C  
HETATM 1894  O3  GOL A1484      25.852  15.978  54.550  1.00 31.55           O  
HETATM 1895  C20 7P0 A1485      26.200   9.537  55.011  1.00 23.76           C  
HETATM 1896  O22 7P0 A1485      25.357   9.908  55.824  1.00 23.63           O  
HETATM 1897  C21 7P0 A1485      27.174   8.473  55.367  1.00 23.65           C  
HETATM 1898  C23 7P0 A1485      28.386   8.375  54.705  1.00 22.94           C  
HETATM 1899  C24 7P0 A1485      29.270   7.379  55.066  1.00 23.29           C  
HETATM 1900  C27 7P0 A1485      28.945   6.494  56.084  1.00 25.00           C  
HETATM 1901  C26 7P0 A1485      27.743   6.593  56.740  1.00 24.36           C  
HETATM 1902  C25 7P0 A1485      26.857   7.588  56.381  1.00 24.78           C  
HETATM 1903  C31 7P0 A1485      27.461   5.635  57.818  1.00 25.75           C  
HETATM 1904  C30 7P0 A1485      28.319   4.672  58.180  1.00 24.07           C  
HETATM 1905  C29 7P0 A1485      29.609   4.556  57.478  1.00 25.32           C  
HETATM 1906  O32 7P0 A1485      30.406   3.678  57.801  1.00 25.28           O  
HETATM 1907  N28 7P0 A1485      29.840   5.480  56.471  1.00 24.37           N  
HETATM 1908  O40 7P0 A1485      26.258   5.778  58.440  1.00 24.52           O  
HETATM 1909  N19 7P0 A1485      26.340  10.095  53.754  1.00 22.92           N  
HETATM 1910  C17 7P0 A1485      25.606  11.279  53.379  1.00 23.80           C  
HETATM 1911  C16 7P0 A1485      24.857  10.883  52.129  1.00 23.43           C  
HETATM 1912  O39 7P0 A1485      25.239  10.002  51.377  1.00 23.29           O  
HETATM 1913  C18 7P0 A1485      26.566  12.395  53.001  1.00 24.90           C  
HETATM 1914  C33 7P0 A1485      27.582  12.714  54.059  1.00 29.71           C  
HETATM 1915  C34 7P0 A1485      27.184  13.218  55.281  1.00 33.09           C  
HETATM 1916  C38 7P0 A1485      28.921  12.515  53.812  1.00 30.23           C  
HETATM 1917  C35 7P0 A1485      28.110  13.521  56.253  1.00 35.15           C  
HETATM 1918  C37 7P0 A1485      29.853  12.810  54.786  1.00 35.22           C  
HETATM 1919  C36 7P0 A1485      29.449  13.314  56.004  1.00 34.77           C  
HETATM 1920  C1  7P0 A1485      18.660  11.217  48.985  1.00 25.05           C  
HETATM 1921  C2  7P0 A1485      18.870  11.394  47.623  1.00 22.51           C  
HETATM 1922  C3  7P0 A1485      20.079  11.894  47.184  1.00 22.74           C  
HETATM 1923  C4  7P0 A1485      21.063  12.214  48.102  1.00 21.97           C  
HETATM 1924  C5  7P0 A1485      20.872  12.050  49.464  1.00 23.06           C  
HETATM 1925  C6  7P0 A1485      19.654  11.546  49.897  1.00 24.39           C  
HETATM 1926 CL7  7P0 A1485      20.365  12.135  45.471  1.00 23.48          CL  
HETATM 1927  N8  7P0 A1485      19.402  11.372  51.276  1.00 25.72           N  
HETATM 1928  C9  7P0 A1485      19.917  10.429  52.124  1.00 26.00           C  
HETATM 1929  N10 7P0 A1485      19.375  10.576  53.320  1.00 26.45           N  
HETATM 1930  N11 7P0 A1485      18.508  11.631  53.191  1.00 26.58           N  
HETATM 1931  N12 7P0 A1485      18.517  12.124  51.957  1.00 26.69           N  
HETATM 1932  C13 7P0 A1485      21.977  12.432  50.406  1.00 22.57           C  
HETATM 1933  C14 7P0 A1485      22.847  11.263  50.797  1.00 23.66           C  
HETATM 1934  N15 7P0 A1485      23.703  11.605  51.914  1.00 22.38           N  
HETATM 1935  S   SO4 A1486      20.004  -8.283  45.418  1.00 53.82           S  
HETATM 1936  O1  SO4 A1486      19.580  -7.069  46.146  1.00 55.38           O  
HETATM 1937  O2  SO4 A1486      21.463  -8.452  45.538  1.00 55.54           O  
HETATM 1938  O3  SO4 A1486      19.397  -9.479  46.042  1.00 53.69           O  
HETATM 1939  O4  SO4 A1486      19.605  -8.167  43.995  1.00 49.58           O  
HETATM 1940  S   SO4 A1487      26.375  -2.225  30.002  0.50 36.62           S  
HETATM 1941  O1  SO4 A1487      26.786  -1.693  31.310  0.50 36.38           O  
HETATM 1942  O2  SO4 A1487      27.146  -1.513  28.961  0.50 35.96           O  
HETATM 1943  O3  SO4 A1487      26.662  -3.677  29.947  0.50 37.00           O  
HETATM 1944  O4  SO4 A1487      24.925  -1.995  29.803  0.50 37.05           O  
HETATM 1945  S   SO4 A1488      27.700  27.703  27.703  0.33 78.34           S  
HETATM 1946  O1  SO4 A1488      28.562  28.553  28.553  0.33 78.64           O  
HETATM 1947  O2  SO4 A1488      28.236  27.697  26.323  0.33 77.00           O  
HETATM 1948  O3  SO4 A1488      27.692  26.326  28.245  0.33 76.48           O  
HETATM 1949  O4  SO4 A1488      26.326  28.254  27.705  0.33 77.01           O  
HETATM 1950  S   SO4 A1489       6.624   7.649  37.283  0.50 48.87           S  
HETATM 1951  O1  SO4 A1489       7.126   8.580  38.309  0.50 46.62           O  
HETATM 1952  O2  SO4 A1489       7.511   7.736  36.100  0.50 49.06           O  
HETATM 1953  O3  SO4 A1489       5.241   8.020  36.904  0.50 48.28           O  
HETATM 1954  O4  SO4 A1489       6.619   6.273  37.823  0.50 46.54           O  
HETATM 1955  O   HOH A2001      23.422   0.495  48.360  1.00 20.33           O  
HETATM 1956  O   HOH A2002      19.105  -1.455  46.819  1.00 30.75           O  
HETATM 1957  O   HOH A2003      15.809  -1.088  49.501  1.00 29.74           O  
HETATM 1958  O   HOH A2004      16.017  -2.177  41.038  1.00 38.46           O  
HETATM 1959  O   HOH A2005      15.475  -3.782  46.168  1.00 40.62           O  
HETATM 1960  O   HOH A2006      26.791  -9.101  42.400  1.00 33.36           O  
HETATM 1961  O   HOH A2007      31.941  -9.579  35.968  1.00 28.14           O  
HETATM 1962  O   HOH A2008      32.658  -3.564  40.494  1.00 28.63           O  
HETATM 1963  O   HOH A2009      31.471  -1.856  39.256  1.00 42.09           O  
HETATM 1964  O   HOH A2010      26.577  -0.881  33.577  1.00 42.47           O  
HETATM 1965  O   HOH A2011      29.930  -2.171  31.924  1.00 48.42           O  
HETATM 1966  O   HOH A2012      33.540  -0.467  40.992  1.00 38.60           O  
HETATM 1967  O   HOH A2013      36.553   1.450  39.890  1.00 26.22           O  
HETATM 1968  O   HOH A2014      38.309  13.722  60.130  1.00 41.78           O  
HETATM 1969  O   HOH A2015      33.613  12.314  57.892  1.00 37.88           O  
HETATM 1970  O   HOH A2016      35.435   0.583  43.359  1.00 27.44           O  
HETATM 1971  O   HOH A2017      27.974   6.113  45.282  1.00 15.40           O  
HETATM 1972  O   HOH A2018      37.820  10.184  29.453  1.00 46.38           O  
HETATM 1973  O   HOH A2019      38.855  17.699  31.751  1.00 46.99           O  
HETATM 1974  O   HOH A2020      36.791  11.416  58.555  1.00 36.44           O  
HETATM 1975  O   HOH A2021      40.962   1.135  60.903  1.00 30.26           O  
HETATM 1976  O   HOH A2022      43.772   2.400  57.550  1.00 37.53           O  
HETATM 1977  O   HOH A2023      33.827   5.410  65.580  1.00 37.60           O  
HETATM 1978  O   HOH A2024      43.486  14.952  59.983  1.00 55.00           O  
HETATM 1979  O   HOH A2025      31.837   1.868  56.060  1.00 31.96           O  
HETATM 1980  O   HOH A2026      28.593   4.711  47.605  1.00 17.60           O  
HETATM 1981  O   HOH A2027      28.191   9.392  51.603  1.00 20.72           O  
HETATM 1982  O   HOH A2028      41.332  24.945  46.045  1.00 51.32           O  
HETATM 1983  O   HOH A2029      30.926  11.109  40.831  1.00 16.81           O  
HETATM 1984  O   HOH A2030      36.409  11.551  31.613  1.00 27.80           O  
HETATM 1985  O   HOH A2031      40.022  14.699  33.213  1.00 56.11           O  
HETATM 1986  O   HOH A2032      45.269  12.478  34.983  1.00 34.79           O  
HETATM 1987  O   HOH A2033      42.171   9.433  31.116  1.00 37.90           O  
HETATM 1988  O   HOH A2034      33.056  20.081  52.749  1.00 31.15           O  
HETATM 1989  O   HOH A2035      28.524  16.478  54.845  1.00 27.43           O  
HETATM 1990  O   HOH A2036      33.008  14.154  56.050  1.00 20.49           O  
HETATM 1991  O   HOH A2037      40.612  15.625  59.653  1.00 38.77           O  
HETATM 1992  O   HOH A2038      45.608   9.954  51.117  1.00 22.23           O  
HETATM 1993  O   HOH A2039      43.803  -0.991  52.348  1.00 23.79           O  
HETATM 1994  O   HOH A2040      46.165  -0.656  55.300  1.00 35.36           O  
HETATM 1995  O   HOH A2041      30.718 -11.534  52.936  1.00 37.13           O  
HETATM 1996  O   HOH A2042      42.111   0.287  44.456  1.00 30.79           O  
HETATM 1997  O   HOH A2043      39.269  -5.830  44.057  1.00 37.29           O  
HETATM 1998  O   HOH A2044      36.120  -3.859  54.700  1.00 26.41           O  
HETATM 1999  O   HOH A2045      34.776  -1.287  54.014  1.00 30.87           O  
HETATM 2000  O   HOH A2046      47.893  -4.994  47.798  1.00 28.10           O  
HETATM 2001  O   HOH A2047      48.216  -9.969  53.611  1.00 32.70           O  
HETATM 2002  O   HOH A2048      47.387   1.658  44.272  1.00 34.57           O  
HETATM 2003  O   HOH A2049      49.098   3.633  47.929  1.00 39.68           O  
HETATM 2004  O   HOH A2050      48.671   6.001  45.869  1.00 28.40           O  
HETATM 2005  O   HOH A2051      48.722  19.135  44.108  1.00 37.48           O  
HETATM 2006  O   HOH A2052      46.412  21.352  41.648  1.00 44.35           O  
HETATM 2007  O   HOH A2053      42.935  22.612  47.024  1.00 38.56           O  
HETATM 2008  O   HOH A2054      44.087  19.251  50.015  1.00 28.96           O  
HETATM 2009  O   HOH A2055      39.556  23.397  47.621  1.00 35.22           O  
HETATM 2010  O   HOH A2056      38.871  25.483  44.387  1.00 41.45           O  
HETATM 2011  O   HOH A2057      37.228  26.163  47.872  1.00 44.58           O  
HETATM 2012  O   HOH A2058      34.066  26.459  48.810  1.00 34.89           O  
HETATM 2013  O   HOH A2059      32.362  27.448  37.577  1.00 31.56           O  
HETATM 2014  O   HOH A2060      26.499  28.384  46.970  1.00 32.95           O  
HETATM 2015  O   HOH A2061      25.926  20.065  52.976  1.00 26.56           O  
HETATM 2016  O   HOH A2062      26.701  25.877  48.012  1.00 22.71           O  
HETATM 2017  O   HOH A2063      22.868  21.054  52.242  1.00 25.84           O  
HETATM 2018  O   HOH A2064      23.408  20.216  44.948  1.00 24.18           O  
HETATM 2019  O   HOH A2065      25.324  20.723  43.284  1.00 18.76           O  
HETATM 2020  O   HOH A2066      25.247  22.595  41.252  1.00 21.24           O  
HETATM 2021  O   HOH A2067      49.059   3.295  42.746  1.00 38.71           O  
HETATM 2022  O   HOH A2068      51.569   6.943  39.569  1.00 50.51           O  
HETATM 2023  O   HOH A2069      48.547   2.279  40.154  1.00 41.47           O  
HETATM 2024  O   HOH A2070      46.267   0.783  39.394  1.00 43.23           O  
HETATM 2025  O   HOH A2071      45.046  -2.194  36.432  1.00 41.95           O  
HETATM 2026  O   HOH A2072      49.040   1.859  32.065  1.00 46.64           O  
HETATM 2027  O   HOH A2073      41.151  -5.761  32.115  1.00 24.82           O  
HETATM 2028  O   HOH A2074      34.775  -2.146  39.048  1.00 33.86           O  
HETATM 2029  O   HOH A2075      34.399  -0.567  30.542  1.00 42.98           O  
HETATM 2030  O   HOH A2076      31.304   3.946  27.656  1.00 28.95           O  
HETATM 2031  O   HOH A2077      32.201   6.497  29.336  1.00 28.64           O  
HETATM 2032  O   HOH A2078      35.329  13.157  29.395  1.00 36.64           O  
HETATM 2033  O   HOH A2079      32.504  18.315  27.845  1.00 34.50           O  
HETATM 2034  O   HOH A2080      15.597   9.204  32.457  1.00 36.11           O  
HETATM 2035  O   HOH A2081      16.481   6.355  33.382  1.00 31.27           O  
HETATM 2036  O   HOH A2082      25.865   4.977  38.084  1.00 24.50           O  
HETATM 2037  O   HOH A2083      25.793   7.621  42.987  1.00 16.74           O  
HETATM 2038  O   HOH A2084      19.573   8.058  58.884  1.00 41.43           O  
HETATM 2039  O   HOH A2085      27.650   0.839  58.178  1.00 42.10           O  
HETATM 2040  O   HOH A2086      25.193  -6.170  50.090  1.00 32.57           O  
HETATM 2041  O   HOH A2087      26.505  -9.386  50.124  1.00 48.19           O  
HETATM 2042  O   HOH A2088      31.401 -10.461  50.279  1.00 34.02           O  
HETATM 2043  O   HOH A2089      22.073  -3.102  34.200  1.00 44.85           O  
HETATM 2044  O   HOH A2090      16.258  -0.488  38.605  1.00 32.38           O  
HETATM 2045  O   HOH A2091      10.033  11.306  34.569  1.00 46.38           O  
HETATM 2046  O   HOH A2092       7.575  20.929  48.321  1.00 40.79           O  
HETATM 2047  O   HOH A2093      11.542  21.964  49.840  1.00 21.08           O  
HETATM 2048  O   HOH A2094      23.138  25.731  41.925  1.00 41.07           O  
HETATM 2049  O   HOH A2095      18.094  29.236  34.972  1.00 34.66           O  
HETATM 2050  O   HOH A2096      29.194  26.307  36.914  1.00 34.45           O  
HETATM 2051  O   HOH A2097      17.364   9.534  42.695  1.00 26.01           O  
HETATM 2052  O   HOH A2098       9.701  10.276  36.897  1.00 35.10           O  
HETATM 2053  O   HOH A2099      12.080   7.639  43.346  1.00 32.54           O  
HETATM 2054  O   HOH A2100      11.759   0.681  47.437  1.00 39.76           O  
HETATM 2055  O   HOH A2101      11.801  -2.816  39.932  1.00 56.87           O  
HETATM 2056  O   HOH A2102      13.160  10.924  49.197  1.00 27.42           O  
HETATM 2057  O   HOH A2103      15.097  12.099  47.572  1.00 30.19           O  
HETATM 2058  O   HOH A2104      22.669  13.308  53.904  1.00 30.59           O  
HETATM 2059  O   HOH A2105      20.478  11.730  20.027  1.00 53.42           O  
HETATM 2060  O   HOH A2106      22.838   3.265  24.006  1.00 47.13           O  
HETATM 2061  O   HOH A2107      25.161  16.833  33.190  1.00 26.36           O  
HETATM 2062  O   HOH A2108      20.322  15.197  51.752  1.00 23.57           O  
HETATM 2063  O   HOH A2109      16.667  17.932  52.230  1.00 43.08           O  
HETATM 2064  O   HOH A2110      12.990   8.702  53.748  1.00 35.55           O  
HETATM 2065  O   HOH A2111      11.973   9.682  45.577  1.00 31.43           O  
HETATM 2066  O   HOH A2112       6.196  10.396  52.068  1.00 43.41           O  
HETATM 2067  O   HOH A2113       6.729   8.086  50.269  1.00 34.65           O  
HETATM 2068  O   HOH A2114       8.537  20.854  51.459  1.00 34.75           O  
HETATM 2069  O   HOH A2115      31.168  24.260  31.952  1.00 31.61           O  
HETATM 2070  O   HOH A2116      32.249  25.239  34.803  1.00 25.97           O  
HETATM 2071  O   HOH A2117      35.871  19.083  31.463  1.00 30.04           O  
HETATM 2072  O   HOH A2118      42.253  25.257  43.389  1.00 41.57           O  
HETATM 2073  O   HOH A2119      27.305  10.179  58.782  1.00 42.93           O  
HETATM 2074  O   HOH A2120      31.542  10.872  62.249  1.00 41.46           O  
HETATM 2075  O   HOH A2121      25.059   9.642  58.779  1.00 44.08           O  
HETATM 2076  O   HOH A2122      29.847  29.847  29.847  0.33 47.51           O  
CONECT  226  340                                                                
CONECT  340  226                                                                
CONECT  991 1520                                                                
CONECT 1250 1381                                                                
CONECT 1381 1250                                                                
CONECT 1458 1664                                                                
CONECT 1520  991                                                                
CONECT 1664 1458                                                                
CONECT 1883 1884 1885                                                           
CONECT 1884 1883                                                                
CONECT 1885 1883 1886 1887                                                      
CONECT 1886 1885                                                                
CONECT 1887 1885 1888                                                           
CONECT 1888 1887                                                                
CONECT 1889 1890 1891                                                           
CONECT 1890 1889                                                                
CONECT 1891 1889 1892 1893                                                      
CONECT 1892 1891                                                                
CONECT 1893 1891 1894                                                           
CONECT 1894 1893                                                                
CONECT 1895 1896 1897 1909                                                      
CONECT 1896 1895                                                                
CONECT 1897 1895 1898 1902                                                      
CONECT 1898 1897 1899                                                           
CONECT 1899 1898 1900                                                           
CONECT 1900 1899 1901 1907                                                      
CONECT 1901 1900 1902 1903                                                      
CONECT 1902 1897 1901                                                           
CONECT 1903 1901 1904 1908                                                      
CONECT 1904 1903 1905                                                           
CONECT 1905 1904 1906 1907                                                      
CONECT 1906 1905                                                                
CONECT 1907 1900 1905                                                           
CONECT 1908 1903                                                                
CONECT 1909 1895 1910                                                           
CONECT 1910 1909 1911 1913                                                      
CONECT 1911 1910 1912 1934                                                      
CONECT 1912 1911                                                                
CONECT 1913 1910 1914                                                           
CONECT 1914 1913 1915 1916                                                      
CONECT 1915 1914 1917                                                           
CONECT 1916 1914 1918                                                           
CONECT 1917 1915 1919                                                           
CONECT 1918 1916 1919                                                           
CONECT 1919 1917 1918                                                           
CONECT 1920 1921 1925                                                           
CONECT 1921 1920 1922                                                           
CONECT 1922 1921 1923 1926                                                      
CONECT 1923 1922 1924                                                           
CONECT 1924 1923 1925 1932                                                      
CONECT 1925 1920 1924 1927                                                      
CONECT 1926 1922                                                                
CONECT 1927 1925 1928 1931                                                      
CONECT 1928 1927 1929                                                           
CONECT 1929 1928 1930                                                           
CONECT 1930 1929 1931                                                           
CONECT 1931 1927 1930                                                           
CONECT 1932 1924 1933                                                           
CONECT 1933 1932 1934                                                           
CONECT 1934 1911 1933                                                           
CONECT 1935 1936 1937 1938 1939                                                 
CONECT 1936 1935                                                                
CONECT 1937 1935                                                                
CONECT 1938 1935                                                                
CONECT 1939 1935                                                                
CONECT 1940 1941 1942 1943 1944                                                 
CONECT 1941 1940                                                                
CONECT 1942 1940                                                                
CONECT 1943 1940                                                                
CONECT 1944 1940                                                                
CONECT 1945 1946 1947 1948 1949                                                 
CONECT 1946 1945                                                                
CONECT 1947 1945                                                                
CONECT 1948 1945                                                                
CONECT 1949 1945                                                                
CONECT 1950 1951 1952 1953 1954                                                 
CONECT 1951 1950                                                                
CONECT 1952 1950                                                                
CONECT 1953 1950                                                                
CONECT 1954 1950                                                                
MASTER      432    0    7    7   15    0   15    6 2075    1   80   19          
END                                                                             
