9UYH

Cryo-EM structure of the G protein-coupled receptor 1 (GPR1) bound to chemerin and beta-arrestin 1 (Conformation 1)

Summary for 9UYH

• Entry DOI: 10.2210/pdb9uyh/pdb
• EMDB information: 64610
• Descriptor: Retinoic acid receptor responder protein 2, Beta-arrestin-1, Nanobody 32, ... (5 entities in total)
• Functional Keywords: g protein-coupled receptor 1, chemerin, beta-arrestin1, signaling protein, membrane protein/immune system, membrane protein-immune system complex
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 145275.65

Authors

Cai, H.,Lin, X.,Zhao, L.,He, M.,Yu, J.,Zhang, B.,Ma, Y.,Xie, C.,Shui, W.,Zhao, Q.,Zhu, Y.,Wu, B. (deposition date: 2025-05-15, release date: 2025-11-19)

• Primary citation: Cai, H.,Lin, X.,Zhao, L.,He, M.,Yu, J.,Zhang, B.,Ma, Y.,Chang, X.,Tang, Y.,Luo, T.,Jiang, J.,Ma, M.,Song, W.,Ma, L.,Chu, X.,Yi, C.,Chen, K.,Han, S.,Xie, C.,Shui, W.,Zhao, Q.,Zhu, Y.,Wu, B.; Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1; Science, 2025; DOI: 10.1126/science.adt8794

Experimental method

ELECTRON MICROSCOPY (3.3 Å)