9SFA

Cyclic nucleotide binding transcription factor Bd2879 - apo form

Summary for 9SFA

• Entry DOI: 10.2210/pdb9sfa/pdb
• Descriptor: Putative regulatory protein (1 entity in total)
• Functional Keywords: cyclic nucleotide binding, transcription factor, dimer, complex, helix-turn-helix, signaling protein
• Biological source: Bdellovibrio bacteriovorus HD100
• Total number of polymer chains: 2
• Total formula weight: 87178.40

Authors

Jenkins, M.R.,Box, H.,Caulton, S.G.,Lovering, A.L. (deposition date: 2025-08-19, release date: 2025-10-22)

Primary citation

Alexander, L.T.,Follonier, O.M.,Kryshtafovych, A.,Abesamis, K.,Bibi-Triki, S.,Box, H.G.,Breyton, C.,Bringel, F.,Carrique, L.,d'Acapito, A.,Dong, G.,DuBois, R.,Fass, D.,Fiesco, J.M.,Fox, D.R.,Grimes, J.M.,Grinter, R.,Jenkins, M.,Kamyshinsky, R.,Keown, J.R.,Lackner, G.,Lammers, M.,Liu, S.,Lovering, A.L.,Malinauskas, T.,Masquida, B.,Palm, G.J.,Siebold, C.,Su, T.,Zhang, P.,Zhou, Z.H.,Fidelis, K.,Topf, M.,Moult, J.,Schwede, T.
Protein Target Highlights in CASP16: Insights From the Structure Providers.
Proteins, 2025

PubMed Abstract: This article presents an in-depth analysis of selected CASP16 targets, with a focus on their biological and functional significance. The authors highlight the most relevant features of the target proteins and discuss how well these were reproduced in the submitted predictions. While the overall performance of structure prediction methods remains impressive, challenges persist, particularly in modeling rare structural motifs, flexible regions, small molecule interactions, posttranslational modifications, and biologically important interfaces. Addressing these limitations can strengthen the role of structure prediction in complementing experimental efforts and advancing both basic research and biomedical applications.

PubMed: 41065010
DOI: 10.1002/prot.70025

Experimental method

X-RAY DIFFRACTION (2.88 Å)