9RWD

High-resolution structure of human SHMT2 with covalently bound PLP (internal aldimine)

Summary for 9RWD

• Entry DOI: 10.2210/pdb9rwd/pdb
• Related: 8aql
• Descriptor: Serine hydroxymethyltransferase, mitochondrial, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
• Functional Keywords: tetrahydrofolate, one-carbon metabolism, cancer therapy target, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 213261.39

Authors

Warlich, A.,Ruszkowski, M.,Nawrot, D. (deposition date: 2025-07-09, release date: 2025-08-13)

• Primary citation: Warlich, A.,Ruszkowski, M.,Nawrot, D.; High-resolution structure of human SHMT2 with covalently bound PLP (internal aldimine); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.3 Å)