9RM6

Crystal Structure of ZIKV NS2B-NS3 protease in complex with ASAP-0027808

This is a non-PDB format compatible entry.

Summary for 9RM6

• Entry DOI: 10.2210/pdb9rm6/pdb
• Descriptor: Serine protease subunit NS2B,Serine protease NS3, 6-chloranyl-~{N}-(2,3-dihydro-1~{H}-isoindol-5-yl)-1~{H}-indazole-4-carboxamide, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: ns2b-ns3 protease, inhibitor, viral protein
• Biological source: Zika virus; More
• Total number of polymer chains: 2
• Total formula weight: 46821.20

Authors

Ni, X.,Marples, P.G.,Godoy, A.S.,Koekemoer, L.,Aschenbrenner, J.C.,Balcomb, B.H.,Fairhead, M.,Lithgo, R.M.,Lee, A.,Kenton, N.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Williams, E.P.,Fearon, D.,von Delft, F. (deposition date: 2025-06-17, release date: 2025-07-23)

• Primary citation: Ni, X.,Marples, P.G.,Godoy, A.S.,Koekemoer, L.,Aschenbrenner, J.C.,Balcomb, B.H.,Fairhead, M.,Lithgo, R.M.,Lee, A.,Kenton, N.,Thompson, W.,Tomlinson, C.W.E.,Wild, C.,Winokan, M.,Williams, E.P.,Fearon, D.,von Delft, F.; Crystal Structure of ZIKV NS2B-NS3 protease in complex with ASAP-0027808; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)