9KN5

Structure of the human 40S ribosome complexed with HCV IRES, eIF1A and eIF3

This is a non-PDB format compatible entry.

Summary for 9KN5

• Entry DOI: 10.2210/pdb9kn5/pdb
• EMDB information: 62453
• Descriptor: Eukaryotic translation initiation factor 1A, X-chromosomal, 40S ribosomal protein S8, 40S ribosomal protein S9, ... (48 entities in total)
• Functional Keywords: hcv ires, ribosome
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 46
• Total formula weight: 1950041.40

Authors

Iwasaki, W.,Kashiwagi, K.,Sakamoto, A.,Nishimoto, M.,Takahashi, M.,Machida, K.,Imataka, H.,Matsumoto, A.,Shichino, Y.,Iwasaki, S.,Imami, K.,Ito, T. (deposition date: 2024-11-18, release date: 2025-12-03)

• Primary citation: Iwasaki, W.,Kashiwagi, K.,Sakamoto, A.,Nishimoto, M.,Takahashi, M.,Machida, K.,Imataka, H.,Matsumoto, A.,Shichino, Y.,Iwasaki, S.,Imami, K.,Ito, T.; Structural Insights into the Role of eIF3 in Translation Mediated by the HCV IRES; Proc.Natl.Acad.Sci.USA, 2025; DOI: 10.1073/pnas.2505538122

Experimental method

ELECTRON MICROSCOPY (3.2 Å)