9IFH

PANDDA analysis - Crystal structure of Trypanosoma brucei trypanothione reductase in complex with Z2856434890

Summary for 9IFH

• Entry DOI: 10.2210/pdb9ifh/pdb
• Related: 9IFE
• Descriptor: Trypanothione reductase, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ... (7 entities in total)
• Functional Keywords: trypanothione reductase, oxidoreductase
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 4
• Total formula weight: 219585.94

Authors

Exertier, C.,Antonelli, L.,Ilari, A.,Fiorillo, A. (deposition date: 2025-02-18, release date: 2025-11-12)

• Primary citation: Exertier, C.,Antonelli, L.,Brufani, V.,Colotti, G.,Ilari, A.,Fiorillo, A.; Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis; Front Chem Biol, Volume 4 - 2025:-, 2025; DOI: 10.3389/fchbi.2025.1605579

Experimental method

X-RAY DIFFRACTION (1.73 Å)