9B2Q

Crystal Structure of Pantothenate Synthetase from Candida albicans.

Summary for 9B2Q

• Entry DOI: 10.2210/pdb9b2q/pdb
• Descriptor: Pantoate--beta-alanine ligase, DI(HYDROXYETHYL)ETHER, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (6 entities in total)
• Functional Keywords: pantoate-beta-alanine ligase, pantothenate synthetase, apo-enzyme, dimer, ligase
• Biological source: Candida albicans
• Total number of polymer chains: 1
• Total formula weight: 37407.13

Authors

Regan, J.,Avad, K.A.,Alaidi, O.,Seetharaman, J.,Palmer, G.E.,Hevener, K.E. (deposition date: 2024-03-15, release date: 2025-03-26)

• Primary citation: Regan, J.,Reitler, P.,Tucker, K.M.,Avad, K.A.,Peters, T.,Hevener, K.E.,Palmer, G.E.; Small molecule inhibitors of fungal pantothenate synthetase can provide a valid and potentially efficacious strategy for antifungal development.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)