9AUC
Human Amylin1 Receptor in Complex with Gs and human Calcitonin Gene-Related Peptide
Summary for 9AUC
Entry DOI | 10.2210/pdb9auc/pdb |
EMDB information | 43877 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (11 entities in total) |
Functional Keywords | amylin receptor, gpcr, ramp3, calcitonin gene-related peptide, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 189471.23 |
Authors | Cao, J.,Belousoff, M.J.,Wootten, D.L.,Sexton, P.M. (deposition date: 2024-02-28, release date: 2024-04-24, Last modification date: 2024-05-22) |
Primary citation | Cao, J.,Belousoff, M.J.,Danev, R.,Christopoulos, A.,Wootten, D.,Sexton, P.M. Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein. Biochemistry, 63:1089-1096, 2024 Cited by PubMed: 38603770DOI: 10.1021/acs.biochem.4c00114 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.4 Å) |
Structure validation
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