8ZPT

Cryo-EM structure of prolactin-releasing peptide recognition with Gq

8ZPT の概要

• エントリーDOI: 10.2210/pdb8zpt/pdb
• EMDBエントリー: 60354
• 分子名称: Guanine nucleotide-binding protein G(324) subunit alpha-1,, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scfv16, ... (6 entities in total)
• 機能のキーワード: melanin-concentrating hormone receptors1, gpcr, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 159380.73

構造登録者

Zhao, L.,Li, Y.,Yuan, Q.,Xu, H.E. (登録日: 2024-05-31, 公開日: 2024-09-25)

• 主引用文献: Li, Y.,Yuan, Q.,He, X.,Zhang, Y.,You, C.,Wu, C.,Li, J.,Xu, H.E.,Zhao, L.H.; Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.; Cell Discov, 10:91-91, 2024; PubMed: 39223120; DOI: 10.1038/s41421-024-00724-6

実験手法

ELECTRON MICROSCOPY (2.96 Å)