8ZPS

Cryo-EM structure of prolactin-releasing peptide recognition with Gi

Summary for 8ZPS

• Entry DOI: 10.2210/pdb8zps/pdb
• EMDB information: 60353
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, SCFV16, ... (6 entities in total)
• Functional Keywords: melanin-concentrating hormone receptors1, gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 159313.55

Authors

Zhao, L.,Li, Y.,Yuan, Q.,Xu, H.E. (deposition date: 2024-05-31, release date: 2024-09-25)

• Primary citation: Li, Y.,Yuan, Q.,He, X.,Zhang, Y.,You, C.,Wu, C.,Li, J.,Xu, H.E.,Zhao, L.H.; Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.; Cell Discov, 10:91-91, 2024; PubMed: 39223120; DOI: 10.1038/s41421-024-00724-6

Experimental method

ELECTRON MICROSCOPY (2.97 Å)