8X94
Structure of human TRPV1 in complex with antagonist --protein purified without CHS
Summary for 8X94
Entry DOI | 10.2210/pdb8x94/pdb |
EMDB information | 38161 |
Descriptor | Transient receptor potential cation channel subfamily V member 1,Green fluorescent protein, 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile, CHOLESTEROL (3 entities in total) |
Functional Keywords | channel, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 503958.88 |
Authors | |
Primary citation | Fan, J.,Ke, H.,Lei, J.,Wang, J.,Tominaga, M.,Lei, X. Structural basis of TRPV1 inhibition by SAF312 and cholesterol. Nat Commun, 15:6689-6689, 2024 Cited by PubMed: 39107321DOI: 10.1038/s41467-024-51085-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.55 Å) |
Structure validation
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