8VPI
CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 462
This is a non-PDB format compatible entry.
Summary for 8VPI
Entry DOI | 10.2210/pdb8vpi/pdb |
Descriptor | Site-specific DNA-methyltransferase (adenine-specific), DNA Strand II, DNA Strand I, ... (6 entities in total) |
Functional Keywords | dna adenine methylation, protein-dna complex, transferase, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Clostridioides difficile More |
Total number of polymer chains | 9 |
Total formula weight | 232575.72 |
Authors | |
Primary citation | Zhou, J.,Chen, Q.,Ren, R.,Yang, J.,Chang, C.,Liu, B.,Horton, J.R.,Li, C.,Maksoud, L.,Yang, Y.,Rotili, D.,Jain, A.K.,Zhang, X.,Blumenthal, R.M.,Chen, T.,Gao, Y.,Valente, S.,Mai, A.,Cheng, X. Quinoline-based compounds can inhibit diverse enzymes that act on DNA Cell Chem Biol, 2024 |
Experimental method | X-RAY DIFFRACTION (2.89 Å) |
Structure validation
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