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8VLK

Crystal structure of the yeast cytosine deaminase containing both open and closed active sites

Summary for 8VLK
Entry DOI10.2210/pdb8vlk/pdb
DescriptorCytosine deaminase, 1,2-ETHANEDIOL, ZINC ION, ... (5 entities in total)
Functional Keywordscytosine deaminase, resistance, heterodimer, antifungal protein
Biological sourceSaccharomyces cerevisiae (brewer's yeast)
Total number of polymer chains4
Total formula weight72075.36
Authors
Picard, M.-E.,Grenier, J.,Despres, P.C.,Dube, A.K.,Landry, C.R.,Shi, R. (deposition date: 2024-01-11, release date: 2024-08-21, Last modification date: 2024-09-04)
Primary citationDespres, P.C.,Dube, A.K.,Picard, M.E.,Grenier, J.,Shi, R.,Landry, C.R.
Compensatory mutations potentiate constructive neutral evolution by gene duplication.
Science, 385:770-775, 2024
Cited by
PubMed: 39146405
DOI: 10.1126/science.ado5719
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.76 Å)
Structure validation

225399

건을2024-09-25부터공개중

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