8VLK
Crystal structure of the yeast cytosine deaminase containing both open and closed active sites
Summary for 8VLK
Entry DOI | 10.2210/pdb8vlk/pdb |
Descriptor | Cytosine deaminase, 1,2-ETHANEDIOL, ZINC ION, ... (5 entities in total) |
Functional Keywords | cytosine deaminase, resistance, heterodimer, antifungal protein |
Biological source | Saccharomyces cerevisiae (brewer's yeast) |
Total number of polymer chains | 4 |
Total formula weight | 72075.36 |
Authors | Picard, M.-E.,Grenier, J.,Despres, P.C.,Dube, A.K.,Landry, C.R.,Shi, R. (deposition date: 2024-01-11, release date: 2024-08-21, Last modification date: 2024-09-04) |
Primary citation | Despres, P.C.,Dube, A.K.,Picard, M.E.,Grenier, J.,Shi, R.,Landry, C.R. Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science, 385:770-775, 2024 Cited by PubMed: 39146405DOI: 10.1126/science.ado5719 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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