8VEJ

De novo designed cholic acid binder: CHD_buttress

Summary for 8VEJ

Entry DOI	10.2210/pdb8vej/pdb
Descriptor	CHD_buttress, CHOLIC ACID (2 entities in total)
Functional Keywords	de novo designed protein, cholic acid, small molecule binder, de novo protein
Biological source	synthetic construct
Total number of polymer chains	2
Total formula weight	55766.08
Authors	Bera, A.K.,Tran, L.,Kang, A.,Baker, D. (deposition date: 2023-12-19, release date: 2024-07-17, Last modification date: 2024-07-31)
Primary citation	An, L.,Said, M.,Tran, L.,Majumder, S.,Goreshnik, I.,Lee, G.R.,Juergens, D.,Dauparas, J.,Anishchenko, I.,Coventry, B.,Bera, A.K.,Kang, A.,Levine, P.M.,Alvarez, V.,Pillai, A.,Norn, C.,Feldman, D.,Zorine, D.,Hicks, D.R.,Li, X.,Sanchez, M.G.,Vafeados, D.K.,Salveson, P.J.,Vorobieva, A.A.,Baker, D. Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science, 385:276-282, 2024 Cited by PubMed: 39024436 DOI: 10.1126/science.adn3780 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.59 Å)

Structure validation