8UV1

Structure of TDP1 complexed with compound IB01

Summary for 8UV1

• Entry DOI: 10.2210/pdb8uv1/pdb
• Descriptor: Tyrosyl-DNA phosphodiesterase 1, 8-(fluorosulfonyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: phosphodiesterase, drug target, cancer, dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 106275.36

Authors

Lountos, G.T.,Zhao, X.Z.,Barakat, I.,Wang, W.,Agama, K.,Al Mahmud, M.R.,Pommier, Y.,Burke, T.R. (deposition date: 2023-11-02, release date: 2024-09-25)

• Primary citation: Lountos, G.T.,Zhao, X.Z.,Barakat, I.,Wang, W.,Agama, K.,Al Mahmud, M.R.,Pommier, Y.,Burke, T.R.; Structure of TDP1 complexed with compound IB01; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.83 Å)