8U9U

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI98

8U9U の概要

• エントリーDOI: 10.2210/pdb8u9u/pdb
• 分子名称: 3C-like proteinase nsp5, (1R,2S,5S)-3-[bis(4-chlorophenoxy)acetyl]-N-{(2S)-1-hydroxy-3-[(3R)-2-oxo-3,4-dihydro-2H-pyrrol-3-yl]propan-2-yl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide (2 entities in total)
• 機能のキーワード: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34414.03

構造登録者

Blankenship, L.R.,Liu, W.R. (登録日: 2023-09-20, 公開日: 2024-09-25)

• 主引用文献: Blankenship, L.R.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)