8U9M

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI95

Summary for 8U9M

• Entry DOI: 10.2210/pdb8u9m/pdb
• Descriptor: 3C-like proteinase nsp5, bis(4-fluorophenyl)methyl (1R,2S,5R)-2-({(2R)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-3-carboxylate (3 entities in total)
• Functional Keywords: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34367.13

Authors

Blankenship, L.R.,Liu, W.R. (deposition date: 2023-09-19, release date: 2024-09-25)

• Primary citation: Blankenship, L.R.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)