8QJ2

Structure of active state MC4R in complex with a potent ligand mimicking nanobody

Summary for 8QJ2

• Entry DOI: 10.2210/pdb8qj2/pdb
• EMDB information: 18442
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, confobody, agonistic nanobody, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 201915.68

Authors

Busch, A.,Jaakola, V.-P.,Masiulis, S. (deposition date: 2023-09-12, release date: 2024-09-25)

• Primary citation: Busch, A.,Jaakola, V.-P.,Masiulis, S.; Structure of active state MC4R in complex with a potent ligand mimicking nanobody; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)