8D86
Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence co-crystallized with a guest small molecule, netropsin.
Summary for 8D86
Entry DOI | 10.2210/pdb8d86/pdb |
Related | 7u6k |
Descriptor | DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3'), DNA (5'-D(A*GP*GP*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*G)-3'), Replication initiation protein, ... (6 entities in total) |
Functional Keywords | replication initiator repe complex co-crystal, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Escherichia coli K-12 More |
Total number of polymer chains | 3 |
Total formula weight | 50995.70 |
Authors | Orun, A.R.,Snow, C.D. (deposition date: 2022-06-07, release date: 2023-06-28, Last modification date: 2023-11-01) |
Primary citation | Orun, A.R.,Shields, E.T.,Dmytriw, S.,Vajapayajula, A.,Slaughter, C.K.,Snow, C.D. Modular Protein-DNA Cocrystals as Precise, Programmable Assembly Scaffolds. Acs Nano, 17:13110-13120, 2023 Cited by PubMed: 37407546DOI: 10.1021/acsnano.2c07282 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.12 Å) |
Structure validation
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