8BZL
Human 20S Proteasome in complex with peptide activator peptide BLM42
Summary for 8BZL
Entry DOI | 10.2210/pdb8bzl/pdb |
Related | 5LE5 |
Descriptor | Proteasome subunit beta type-3, Proteasome subunit beta type-2, Proteasome subunit beta type-5, ... (20 entities in total) |
Functional Keywords | activator peptide, 20s proteasome, protein degradation, threonine protease, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 34 |
Total formula weight | 777602.30 |
Authors | Henneberg, F.,Chari, A.,Jankowska, E.,Witkowska, J. (deposition date: 2022-12-15, release date: 2023-12-27) |
Primary citation | Gizynska, M.,Karpowicz, P.,Sowik, D.,Trepczyk, K.,Witkowska, J.,Hennenberg, F.,Chari, A.,Gieldon, A.,Pierzynowska, K.,Gaffke, L.,Wegrzyn, G.,Jankowska, E. Peptidic, Blm10-based activators of human 20S proteasome in vitro and in cellulo enhance degradation of proteins connected with neurodegeneration. To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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