8WQW
Cryo-EM structure of bsAb3 Fab-Gn-Gc complex
Summary for 8WQW
Entry DOI | 10.2210/pdb8wqw/pdb |
EMDB information | 37756 |
Descriptor | Glycoprotein C, bsAb3 Fab-heavy chain, bsAb3 Fab-light chain, ... (6 entities in total) |
Functional Keywords | complex, viral protein, protein binding |
Biological source | Dabie bandavirus (Severe fever with thrombocytopenia syndrome virus) More |
Total number of polymer chains | 6 |
Total formula weight | 230486.08 |
Authors | |
Primary citation | Chang, Z.,Gao, D.,Liao, L.,Sun, J.,Zhang, G.,Zhang, X.,Wang, F.,Li, C.,Oladejo, B.O.,Li, S.,Chai, Y.,Hu, Y.,Lu, X.,Xiao, H.,Qi, J.,Chen, Z.,Gao, F.,Wu, Y. Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model. Proc.Natl.Acad.Sci.USA, 121:e2400163121-e2400163121, 2024 Cited by PubMed: 38830098DOI: 10.1073/pnas.2400163121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.27 Å) |
Structure validation
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