8VT3
cryo-EM structure of HMPV (MPV-2cREKR)
Summary for 8VT3
Entry DOI | 10.2210/pdb8vt3/pdb |
EMDB information | 43517 |
Descriptor | Prefusion of HMPV (MPV-2cREKR), N-fragment, Prefusion of HMPV (MPV-2cREKR), C-fragment, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | prefusion, hmpv, cryo-em, virus, viral protein |
Biological source | Human metapneumovirus More |
Total number of polymer chains | 6 |
Total formula weight | 154182.65 |
Authors | Yu, X.,Langedijk, J.P.M. (deposition date: 2024-01-25, release date: 2024-07-31, Last modification date: 2024-08-07) |
Primary citation | Bakkers, M.J.G.,Ritschel, T.,Tiemessen, M.,Dijkman, J.,Zuffiano, A.A.,Yu, X.,van Overveld, D.,Le, L.,Voorzaat, R.,van Haaren, M.M.,de Man, M.,Tamara, S.,van der Fits, L.,Zahn, R.,Juraszek, J.,Langedijk, J.P.M. Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer. Nat Commun, 15:6270-6270, 2024 Cited by PubMed: 39054318DOI: 10.1038/s41467-024-50659-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.33 Å) |
Structure validation
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